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    Cardiac mapping instrument with shapeable electrode
    32.
    发明授权
    Cardiac mapping instrument with shapeable electrode 有权
    具有可塑电极的心脏测绘仪

    公开(公告)号：US08623010B2

    公开(公告)日：2014-01-07

    申请号：US12480926

    申请日：2009-06-09

    申请人： Jon M. Ocel ,  Roderick E. Briscoe ,  David E. Francischelli ,  Scott E. Jahns ,  James R. Keogh ,  Katherine S. Jolly ,  Matthew D. Bonner

    发明人： Jon M. Ocel ,  Roderick E. Briscoe ,  David E. Francischelli ,  Scott E. Jahns ,  James R. Keogh ,  Katherine S. Jolly ,  Matthew D. Bonner

    IPC分类号： A61B18/14

    CPC分类号： A61B5/042 ,  A61B5/7475 ,  A61B18/14 ,  A61B2017/2927 ,  A61B2018/1472 ,  A61N1/056

    摘要： An instrument including an elongated shaft and a non-conductive handle is disclosed. The shaft defines a proximal section and a distal section. The distal section forms an electrically conductive tip. Further, the shaft is adapted to be transitionable from a straight state to a first bent state. The shaft is capable of independently maintaining the distinct shapes associated with the straight state and the first bent state. The handle is rigidly coupled to the proximal section of the shaft. The instrument is useful for epicardial pacing and/or mapping of the heart for temporary pacing on a beating heart, for optimizing the placement of ventricular leads for the treatment of patients with congestive heart failure and ventricular dysynchrony and/or for use in surgical ablation procedures.

    摘要翻译： 公开了一种包括细长轴和非导电手柄的仪器。 轴限定近端部分和远端部分。 远侧部分形成导电尖端。 此外，轴适于从直状态转变到第一弯曲状态。 轴能够独立地保持与直线状态和第一弯曲状态相关联的不同形状。 手柄刚性地联接到轴的近端部分。 该仪器可用于心脏起搏和/或心脏在心脏跳动中临时起搏的作用，以优化用于治疗患有充血性心力衰竭和心室异常不适和/或用于外科手术切除手术的患者的心室导线的放置 。

    DEVICES AND METHODS FOR INTERSTITIAL INJECTION OF BIOLOGIC AGENTS INTO TISSUE
    35.
    发明申请
    DEVICES AND METHODS FOR INTERSTITIAL INJECTION OF BIOLOGIC AGENTS INTO TISSUE 有权
    用于生物组织的内部注射用于组织的装置和方法

    公开(公告)号：US20100063475A1

    公开(公告)日：2010-03-11

    申请号：US12621037

    申请日：2009-11-18

    申请人： Scott E. Jahns ,  Gary S. Oehme ,  Matthew D. Bonner ,  James R. Keogh

    发明人： Scott E. Jahns ,  Gary S. Oehme ,  Matthew D. Bonner ,  James R. Keogh

    IPC分类号： A61M31/00 ,  A61M5/32

    CPC分类号： A61B17/3478 ,  A61B17/00234 ,  A61B17/205 ,  A61B2017/00247 ,  A61B2017/00876 ,  A61B2017/2936 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2018/00392 ,  A61B2090/034 ,  A61M5/32 ,  A61M2025/0086 ,  A61M2025/0087

    摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for transversely driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force transverse to the shaft. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.

    摘要翻译： 将生物制剂注入组织的装置和方法。 设备具有细长的轴和远端注射头，用于将针横向驱动到组织中，并通过针将药剂注射到组织中。 沿着轴引导的纵向力可以平移到与轴垂直的针驱动力​​。 一些装置提供可控的可变针穿透深度。 设备包括利用四个连杆缩放仪，齿条和小齿轮的机械针驱动器和用于将第一滚针轴承体朝向第二组织接触体驱动的驱动轭。 其他装置包括用于驱动和缩回针的可充气构件。 还有其它装置包括用于在延伸和/或缩回位置偏置针的磁体。 本发明包括用心外膜将心脏细胞前体细胞注入梗死心肌组织的微创方法。

    Methods and Apparatus for Locating Body Vessels and Occlusions in Body Vessels
    36.
    发明申请
    Methods and Apparatus for Locating Body Vessels and Occlusions in Body Vessels 审中-公开
    用于定位体内血管和闭塞的方法和装置

    公开(公告)号：US20090137900A1

    公开(公告)日：2009-05-28

    申请号：US12362658

    申请日：2009-01-30

    申请人： Mathew D. Bonner ,  Cynthia T. Clague ,  Scott E. Jahns ,  James R. Keogh

    发明人： Mathew D. Bonner ,  Cynthia T. Clague ,  Scott E. Jahns ,  James R. Keogh

    IPC分类号： A61B5/05

    CPC分类号： A61B5/06 ,  A61B5/062 ,  A61B2017/00022 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/22001 ,  A61B2090/061

    摘要： Methods and apparatus employed to locate body vessels and occlusions in body vessels finding particular utility in cardiac surgery, particularly minimally invasive cardiac surgery to locate cardiac arteries and occlusions in cardiac arteries are disclosed. An elongated vessel lumen probe incorporating a lumen probe element at or near the elongated vessel lumen probe distal end is advanced into the vessel lumen. A vessel surface probe manipulated by the surgeon and having a surface probe element sensor is employed to detect the lumen probe element and to follow the progress of the vessel lumen probe element as it approaches and is advanced through or is blocked by an occlusion. In the location of a coronary artery, the surface probe element sensor is moved about against the epicardium over the suspected location of the artery of interest until a surface probe element sensor of the present invention at the surface probe distal end interacts with the lumen probe element of the vessel lumen probe.

    摘要翻译： 公开了用于定位身体血管和身体血管闭塞的方法和装置，其在心脏手术中特别有用，特别是在心脏动脉中定位心脏动脉和闭塞的微创心脏手术。 在细长血管腔探针末端处或其附近并入管腔探针元件的细长血管腔探针被推入血管内腔。 由外科医生操作并具有表面探针元件传感器的血管表面探针被用于检测内窥镜元件，并且随着血管腔探针元件的进入而进入并被阻塞阻塞。 在冠状动脉的位置，表面探针元件传感器在目标动脉的疑似位置上靠近心外膜移动，直到本发明的表面探针元件传感器在表面探针远端与内腔探针元件相互作用 的血管腔探针。