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公开(公告)号:US4450159A
公开(公告)日:1984-05-22
申请号:US64783
申请日:1979-08-08
IPC分类号: C07D279/06 , A61K31/54 , A61K31/425
CPC分类号: C07D279/06
摘要: Novel cyclized .omega.-carboxyethyl mono or dithiocarbanilic acids are disclosed as immunoregulatory agents, useful in the treatment of organ transplant reject phenomenon and autoimmune diseases particularly where a delayed hypersensitivity component has been established, such as multiple sclerosis.Additionally described is the use of certain cyclized .omega.-carboxyalkyl mono- or dithiocarbamic acids and certain cyclized .omega.-carboxyalkyl mono- or dithiocarbamic acids.
摘要翻译: 公开了新的环化的ω-羧乙基单或二硫代氨基苯甲酸作为免疫调节剂,可用于治疗器官移植排斥现象和自身免疫性疾病,特别是已经建立延迟超敏反应成分的多发性硬化症。 另外描述了某些环化的ω-羧甲基单或二硫代氨基甲酸和某些环化的ω-羧甲基烷基单或二硫代氨基甲酸的用途。
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公开(公告)号:US09014348B2
公开(公告)日:2015-04-21
申请号:US13554545
申请日:2012-07-20
申请人: David J. Anderson
发明人: David J. Anderson
CPC分类号: H04M3/5307 , G06F17/279 , H04M1/64 , H04M3/53333
摘要: Embodiments are provided for utilizing speech analytics for automatically managing messages in a communications network. A message from a calling party to an unavailable called party is recorded in a messaging management module. The messaging management module automatically identifies a category for assigning to the content of the message based on information associated with the unavailable called party or a calling party and associates a language model with the message content based on the category. An analysis module utilizes the language model to identify grammar making up the message content. The messaging management module automatically performs a messaging management function on the message content based on a set of rules. The messaging management function may include automatically determining a priority for the message (enabling the message to be retrieved out of order) or automatically triggering an action in response to the message which is directed to the unavailable called party.
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公开(公告)号:US08997626B2
公开(公告)日:2015-04-07
申请号:US13079968
申请日:2011-04-05
申请人: David J. Anderson
发明人: David J. Anderson
CPC分类号: F16K17/0406 , F15B15/18 , F15B2211/20515 , F15B2211/20561 , F15B2211/3051 , F15B2211/50527 , F15B2211/785 , F16K15/044 , F16K17/08
摘要: A manual release valve is provided for a electro-hydraulic actuator of the type including a piston movable in a cylinder and defining a piston side chamber and a rod side chamber, the valve threadedly attached to the housing of the actuator and extending at least partially within the fluid housing conduits, the valve moveable from a closed position fully seated in the housing to an open position for fluidly connecting both the piston side chamber and the rod side chamber to the reservoir, the valve further including a pressure relief portion that is operable when the valve is in the closed position for relieving pressure from at least one of the piston side chamber or the rod side chamber.
摘要翻译: 提供了一种用于电动液压致动器的手动释放阀,其包括可在气缸中移动并限定活塞侧室和杆侧室的活塞,所述活塞螺纹连接到致动器的壳体并且至少部分地延伸 所述流体壳体导管,所述阀可以从完全安置在所述壳体中的关闭位置移动到用于将所述活塞侧室和所述杆侧室两者流体连接到所述储存器的打开位置,所述阀还包括压力释放部分, 阀处于关闭位置,用于从活塞侧室或杆侧室中的至少一个释放压力。
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公开(公告)号:US08916355B2
公开(公告)日:2014-12-23
申请号:US11703062
申请日:2007-02-05
申请人: David J. Anderson , Xinzhong Dong , Mark Zylka , Sang-kyou Han , Melvin I. Simon
发明人: David J. Anderson , Xinzhong Dong , Mark Zylka , Sang-kyou Han , Melvin I. Simon
IPC分类号: G01N33/567 , G01N33/50 , G01N33/543 , C07K14/705 , A61K38/00
CPC分类号: C07K14/70571 , A61K38/00 , C07K14/705 , G01N33/5041 , G01N33/5058 , G01N33/5082 , G01N33/54366 , G01N2333/726 , G01N2500/02
摘要: The invention relates generally to novel genes expressed in normal but not Neurogenin-1-deficient animals. The invention relates specifically to a novel family of G protein-coupled receptors and a novel family of two-transmembrane segment proteins that are expressed in dorsal root ganglia, and a method of screening for genes specifically expressed in nociceptive sensory neurons.
摘要翻译: 本发明一般涉及在正常但不是神经元素-1缺陷的动物中表达的新基因。 本发明具体涉及G蛋白偶联受体的新家族和在背根神经节中表达的双跨膜区段蛋白质的新家族,以及筛选在伤害性感觉神经元中特异性表达的基因的方法。
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公开(公告)号:US08914524B1
公开(公告)日:2014-12-16
申请号:US13048941
申请日:2011-03-16
IPC分类号: G06F15/16
CPC分类号: H04L67/02 , G06F17/30283 , G06F17/30289 , G06F17/30899 , G06Q30/06 , H04L67/1095
摘要: Disclosed are various embodiments for generating a network page having a data density that corresponds to a network page load time for a client in communication with an electronic commerce system. In one embodiment, the electronic commerce system determines a network page load time for a client and draws an association between the client and a data density based at least in part on the network page load time. The electronic commerce system generates a network page having the data density and serves the network page for the client.
摘要翻译: 公开了用于生成具有对应于与电子商务系统通信的客户端的网页加载时间的数据密度的网页的各种实施例。 在一个实施例中,电子商务系统至少部分地基于网页加载时间来确定客户端的网页加载时间并且在客户端和数据密度之间绘制关联。 电子商务系统生成具有数据密度的网页,并为客户端提供网页。
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公开(公告)号:US20130165385A1
公开(公告)日:2013-06-27
申请号:US13533279
申请日:2012-06-26
申请人: David J. Anderson , Qiufu Ma , Lukas Sommer
发明人: David J. Anderson , Qiufu Ma , Lukas Sommer
IPC分类号: C07K14/47
CPC分类号: C07K14/475
摘要: The invention relates to novel neurogenin proteins, nucleic acids and antibodies.
摘要翻译: 本发明涉及新型神经元蛋白,核酸和抗体。
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公开(公告)号:US08345831B2
公开(公告)日:2013-01-01
申请号:US11881564
申请日:2007-07-27
申请人: David J. Anderson
发明人: David J. Anderson
IPC分类号: H04M1/64
CPC分类号: H04M3/42221 , G10L15/26 , G10L15/265 , H04M1/656 , H04M3/51 , H04M3/5175 , H04M3/5183 , H04M2201/40 , H04M2203/301 , H04M2203/303 , H04M2203/5018
摘要: Embodiments are provided for the automatic real-time recording and processing of media in a communications network based on the context of the media. In one embodiment, a media stream is received in an analysis module in a service platform in the communications network. The media stream may represent a communication session between a calling party and a call center in the network. The incoming media steam is analyzed to identify words comprising a context of the communication session. A determination is then made as to whether the context of the communication session is related to a set of business rules associated with the service platform which may automatically trigger the retention of a recording of the communication session. If the context of the communication session is related to the set of business rules, the retention of the communication session is automatically triggered in real-time at a recording module.
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公开(公告)号:US08232076B2
公开(公告)日:2012-07-31
申请号:US12941936
申请日:2010-11-08
申请人: David J. Anderson , Qiufa Ma , Lukas Sommer
发明人: David J. Anderson , Qiufa Ma , Lukas Sommer
IPC分类号: C12P21/061 , C12P21/02 , C12N15/12
CPC分类号: C07K14/475
摘要: The invention relates to novel neurogenin proteins, nucleic acids and antibodies.
摘要翻译: 本发明涉及新型神经元蛋白,核酸和抗体。
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公开(公告)号:US08161742B2
公开(公告)日:2012-04-24
申请号:US12186215
申请日:2008-08-05
IPC分类号: F16D31/02
CPC分类号: F04B35/045
摘要: An electro-hydraulic actuator includes a hydraulic pump, an electric motor operatively connected to the hydraulic pump and operable for driving the pump, an actuator moveable in response to fluid flow from the pump, and a housing for the pump, electric motor and actuator. The housing has a base member that is adapted to be modified into various configurations for forming an attachment interface for mounting of the electro-hydraulic actuator.
摘要翻译: 电动液压致动器包括液压泵,可操作地连接到液压泵并可用于驱动泵的电动马达,响应于来自泵的流体流动而可移动的致动器以及用于泵,电动马达和致动器的壳体。 壳体具有适于被修改成各种构造的基部构件,用于形成用于安装电动液压致动器的附接界面。
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公开(公告)号:US20110195901A1
公开(公告)日:2011-08-11
申请号:US13078150
申请日:2011-04-01
申请人: Hai U. Wang , Zhoufeng Chen , David J. Anderson
发明人: Hai U. Wang , Zhoufeng Chen , David J. Anderson
IPC分类号: A61K38/00 , A01K67/033 , G01N33/00 , A61P9/00 , B65D90/00
CPC分类号: C12N15/8509 , A01K67/0275 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0375 , A61K39/3955 , A61K49/00 , A61K49/0002 , A61K49/0008 , C07K14/705 , C07K16/2866 , C07K16/30 , C07K2317/76 , C12N5/0691 , C12N2503/02 , G01N33/573 , G01N33/6863 , G01N2333/52
摘要: Arterial and venous endothelial cells are molecularly distinct from the earliest stages of angiogenesis. This distinction is revealed by expression on arterial cells of a transmembrane ligand, called EphrinB2 whose receptor EphB4 is expressed on venous cells. Targeted disruption of the EphrinB2 gene prevents the remodeling of veins from a capillary plexus into properly branched structures. Moreover, it also disrupts the remodeling of arteries, suggesting that reciprocal interactions between pre-specified arterial and venous endothelial cells are necessary for angiogenesis. This distinction can be used to advantage in methods to alter angiogenesis, methods to assess the effect of drugs on artery cells and vein cells, and methods to identify and isolate artery cells and vein cells, for example.
摘要翻译: 动脉和静脉内皮细胞与血管生成的最早阶段分子截然不同。 通过在受体EphB4在静脉细胞上表达的称为EphrinB2的跨膜配体的动脉细胞上的表达来揭示这种区别。 EphrinB2基因的靶向破坏阻止了从毛细血管丛将静脉重构成适当的分支结构。 此外,它还破坏动脉重塑,这表明预先规定的动脉和静脉内皮细胞之间的相互作用对于血管发生是必需的。 这种区别可用于改变血管生成的方法,评估药物对动脉细胞和静脉细胞的作用的方法,以及鉴定和分离动脉细胞和静脉细胞的方法。
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