Derivatives of isoindigo, indigo and indirubin and methods of treating cancer
    31.
    发明授权
    Derivatives of isoindigo, indigo and indirubin and methods of treating cancer 有权
    异靛素,靛蓝和靛玉红的衍生物和治疗癌症的方法

    公开(公告)号:US06933315B2

    公开(公告)日:2005-08-23

    申请号:US10864458

    申请日:2004-06-10

    CPC分类号: C07H19/23 C07D209/34

    摘要: A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Methods of synthesizing these derivatives is also taught. In addition, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal having solid tumor cancer. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.

    摘要翻译: 称为NATURA的化合物是Isoindigo的衍生物,可用于帮助患者的一般健康,具体有益于预防或治疗癌症。 该化合物和其它相关的Isoindigo,Indigo和Indirubin衍生物被设计成使得化合物的生物活性或生物利用度增加。 还教导了合成这些衍生物的方法。 另外,包括治疗有效量的这些衍生物和药学上可接受的载体中的至少一种的药物组合物。 教导了使用这些药物组合物和化合物的方法,其中向具有实体肿瘤癌症的动物施用治疗有效量。 药物组合物或化合物可以重新施用于动物直到达到所需的治疗或结果。

    Near real time delivery of variable bit rate media streams
    32.
    发明授权
    Near real time delivery of variable bit rate media streams 有权
    可实时传送可变比特率媒体流

    公开(公告)号:US08474001B2

    公开(公告)日:2013-06-25

    申请号:US12368782

    申请日:2009-02-10

    IPC分类号: H04N7/173

    摘要: A method of delivering a variable bit rate (VBR) media stream in near real time includes identifying a selected media asset to be streamed to a media receiver, receiving an available access bandwidth at which the media receiver can receive data, and initiating a session setup for delivery of the selected media asset. The method further includes calculating a delay in decoding a media stream associated with the selected media asset at the media receiver based on the available access bandwidth, and a calculated required minimum transmission rate of a VBR media stream representative of the selected media asset. The method further includes transmitting the selected media asset at the required minimum transmission rate of the VBR media stream and providing the calculated delay to the media receiver such that the media receiver begins decoding the media stream in accordance with the calculated delay.

    摘要翻译: 一种在近实时传送可变比特率(VBR)媒体流的方法包括识别要流媒体接收器的所选择的媒体资产,接收媒体接收者可以在其接收数据的可用接入带宽,以及发起会话建立 用于传送所选媒体资产。 该方法还包括基于可用的访问带宽以及代表所选择的媒体资产的VBR媒体流的计算所需的最小传输速率来计​​算在媒体接收器处解码与所选择的媒体资产相关联的媒体流的延迟。 该方法还包括以所需的VBR媒体流的最小传输速率发送所选择的媒体资产,并将所计算的延迟提供给媒体接收机,使得媒体接收机根据所计算的延迟开始解码媒体流。

    Removing jitter in RTP streaming media streams
    34.
    发明授权
    Removing jitter in RTP streaming media streams 有权
    消除RTP流媒体流中的抖动

    公开(公告)号:US07499446B1

    公开(公告)日:2009-03-03

    申请号:US10135223

    申请日:2002-04-29

    IPC分类号: H04L12/28

    摘要: The present invention addresses the issue of jitter and clock drifting in streaming media applications. The present invention utilizes the Real Time Transaction Protocol (RTP) to embed MPEG packets within RTP packets in a Multiple Program Transport Stream (MPTS). Each MPEG packet in an MPTS stream is tagged at a gateway with: an arrival timestamp, a per-flow index and internal index to identify where the packet resides in an RTP packet and within a stream. After demultiplexing, this information is utilized in conjunction with the sending timestamp of each RTP packet to create a sending time for each MPEG packet to aid in the reduction of jitter and clock drifting.

    摘要翻译: 本发明解决了流媒体应用中抖动和时钟漂移的问题。 本发明利用实时事务协议(RTP)将多个节目传输流(MPTS)中的RTP分组中的MPEG分组嵌入到RTP分组中。 MPTS流中的每个MPEG分组在网关处被标记为:到达时间戳,每流索引和内部索引,以标识分组驻留在RTP分组中以及流内的哪里。 解复用后,该信息与每个RTP分组的发送时间戳一起使用,以创建每个MPEG分组的发送时间,以帮助减少抖动和时钟漂移。

    Efficient available bandwidth usage in transmission of compressed video data
    35.
    发明授权
    Efficient available bandwidth usage in transmission of compressed video data 有权
    压缩视频数据传输中的有效可用带宽使用

    公开(公告)号:US07292602B1

    公开(公告)日:2007-11-06

    申请号:US10034057

    申请日:2001-12-27

    IPC分类号: H04J3/16

    摘要: Described herein are systems and methods for multiplexing and transmitting video data. The systems and methods use excess bandwidth in a channel available after meeting minimum transmission requirements for all bitstreams. A network device of the invention flexibly allocates this available bandwidth to minimize further rate reduction. More specifically, the network device periodically determines the available bandwidth, and divides the available bandwidth among multiple incoming bitstreams being multiplexed in order to increase downstream decoder buffer levels. By maintaining increased decoder buffer levels, future rate reduction of the video data may be avoided or applied to a lesser degree. Minimizing rate reduction in this manner improves bandwidth usage efficiency, and thus improves video data transmission and end-user output video quality.

    摘要翻译: 这里描述了用于复用和传输视频数据的系统和方法。 在满足所有比特流的最小传输要求之后,系统和方法在可用信道中使用超额带宽。 本发明的网络设备灵活地分配该可用带宽以最小化进一步的速率降低。 更具体地,网络设备周期性地确定可用带宽,并且将被复用的多个输入比特流之间的可用带宽划分,以便增加下行译码器缓冲器电平。 通过维持增加的解码器缓冲器电平,视频数据的未来速率降低可以在较小程度上被避免或应用。 以这种方式降低速率降低了带宽使用效率,从而改善了视频数据传输和终端用户输出视频质量。

    IPTV off-path admission control signaling in the presence of network address translation
    36.
    发明授权
    IPTV off-path admission control signaling in the presence of network address translation 有权
    IPTV在路由接纳控制信令中存在网络地址转换

    公开(公告)号:US08973065B2

    公开(公告)日:2015-03-03

    申请号:US12504982

    申请日:2009-07-17

    摘要: Off-path admission control signaling in the presence of a network address translation (NAT) device may be provided. In response to a request for a content asset, a placeholder classifier may be created. The placeholder classifier may be used to allocate resources for providing the content asset to the client from a content server. The content server may communicate with the client, traversing the NAT device to identify a destination address and port for the client to which the content will be provided. The placeholder classifier may then be updated with the destination address and port.

    摘要翻译: 可以提供在存在网络地址转换(NAT)设备的情况下的非路径准入控制信令。 响应于对内容资产的请求,可以创建占位符分类器。 占位符分类器可以用于从内容服务器分配用于向客户端提供内容资源的资源。 内容服务器可以与客户端进行通信,遍历NAT设备以识别要提供内容的客户端的目的地地址和端口。 然后可以使用目标地址和端口更新占位符分类器。

    Efficiently Delivering Time-Shifted Media Content via Content Delivery Networks (CDNs)
    37.
    发明申请
    Efficiently Delivering Time-Shifted Media Content via Content Delivery Networks (CDNs) 审中-公开
    通过内容交付网络(CDN)有效地提供时间偏移的媒体内容

    公开(公告)号:US20140074961A1

    公开(公告)日:2014-03-13

    申请号:US13612425

    申请日:2012-09-12

    IPC分类号: G06F15/167

    摘要: Example embodiments herein provide for efficient distribution of content in a content distribution network (CDN) by a CDN server. The content is efficiently distributed by associating live content and time-shifted content with a common resource identifier, which may (in some instances) avoid re-transporting content across the network. To facilitate this, an entry point CDN server is configured to map the common resource identifier to a permanent storage location (that is itself associated with a different resource identifier) after expiration of the live viewing period.

    摘要翻译: 这里的示例性实施例提供了由CDN服务器在内容分发网络(CDN)中有效地分发内容。 通过将实况内容和时间偏移的内容与公共资源标识符相关联来有效地分发内容,其可以(在某些情况下)避免在整个网络上重新传输内容。 为了便于此,入口点CDN服务器被配置为在实时观看期间到期之后将公共资源标识符映射到永久存储位置(其本身与不同的资源标识符相关联)。

    Distributing digital video content to multiple end-user devices
    38.
    发明授权
    Distributing digital video content to multiple end-user devices 有权
    将数字视频内容分发到多个最终用户设备

    公开(公告)号:US08468572B2

    公开(公告)日:2013-06-18

    申请号:US12055772

    申请日:2008-03-26

    IPC分类号: H04N7/58 H04N7/24 H04L12/56

    摘要: A technique for managing the distribution of digital video content to multiple end-user devices is disclosed. The technique involves statistically multiplexing multiple VBR encoded video streams into an access channel, such as a data over cable service interface specifications (DOCSIS) bonded group, and utilizing quality of service capabilities of an edge device, such as a cable modem termination system (CMTS) or an edge quadrature amplitude modulation (QAM) device, to buffer and schedule IP packets, which carry the VBR encoded video streams, so that packets are not dropped during periods of congestion. Utilizing the quality of service capabilities of an edge device makes it possible to statistically multiplex VBR encoded video streams in a narrowcast application such as Video on Demand (VOD) or Switched Digital Video (SDV) while eliminating the need for process intensive transrating/transcoding operations.

    摘要翻译: 公开了一种用于管理数字视频内容到多个终端用户设备的分发的技术。 该技术涉及将多个VBR编码视频流统计复用为接入信道,诸如通过电缆业务接口规范(DOCSIS)绑定组的数据,并且利用诸如电缆调制解调器终端系统(CMTS)之类的边缘设备的服务质量 )或边缘正交幅度调制(QAM)设备,以缓冲和调度携带VBR编码视频流的IP分组,使得在拥塞期间分组不被丢弃。 利用边缘设备的服务质量使得可以在诸如视频点播(VOD)或交换数字视频(SDV)之类的窄播应用中对VBR编码视频流进行统计复用,同时消除对进程密集型转换/转码操作的需要 。

    Dynamic video-on-demand navigation and on demand ingest
    39.
    发明授权
    Dynamic video-on-demand navigation and on demand ingest 有权
    动态视频点播导航和按需摄取

    公开(公告)号:US08056105B2

    公开(公告)日:2011-11-08

    申请号:US12138233

    申请日:2008-06-12

    申请人: Xiaomei Liu Gil Cruz

    发明人: Xiaomei Liu Gil Cruz

    IPC分类号: H04N7/173

    摘要: A technique for supporting over-the-top video-on-demand separates metadata ingest and real content ingest such that navigation needs only the metadata ingest to have been completed. The real content ingest can occur later if the navigation results in the real content being selected and if the selected content has not been ingested already. Additionally, content identifiers with limited range are used over and over to identify a practically unlimited range of available over-the-top content by mapping virtual content identifiers to dynamic content. The content metadata and real content ingest are synchronized on a video-on-demand system using the dynamically allocated content identifiers. Playlists can be virtualized with a logical content identifier which maps to a list of virtual content identifiers. Existing video-on-demand infrastructures can simultaneously support both static and dynamic content with preexisting video-on-demand back offices and video-on-demand clients.

    摘要翻译: 用于支持顶级视频点播的技术分离元数据摄取和实际内容摄取,使得导航仅需要元数据摄取才能完成。 如果导航导致选择真实内容并且所选择的内容已经没有被摄取,则真实的内容摄取可以发生。 此外,通过将虚拟内容标识符映射到动态内容,一次又一次地使用具有有限范围的内容标识符来标识实际上无限范围的可用顶层内容。 使用动态分配的内容标识符,在视频点播系统上同步内容元数据和实际内容摄取。 可以使用映射到虚拟内容标识符列表的逻辑内容标识符虚拟化播放列表。 现有的视频点播基础设施可以同时支持既有的视频点播后台和视频点播客户端的静态和动态内容。

    Switched Unicast in an Internet Protocol Television Environment
    40.
    发明申请
    Switched Unicast in an Internet Protocol Television Environment 有权
    互联网协议电视环境中的交换单播

    公开(公告)号:US20100238924A1

    公开(公告)日:2010-09-23

    申请号:US12408335

    申请日:2009-03-20

    申请人: Xiaomei Liu

    发明人: Xiaomei Liu

    IPC分类号: H04L12/56 H04N7/173

    摘要: In one embodiment, a processing device is coupled between at least one content source and at least one subscriber device within an Internet Protocol television (IPTV) system in order to receive a plurality of service flows from the at least one content source and to process multicast service flow requests from the at least one subscriber device. The processing device includes a map module to map a service flow from a content source to a multicast service flow based on a multicast service flow request from a particular subscriber device and a unicast module to assign a unique identifier to the mapped multicast service flow to convert the mapped multicast service flow to a unicast delivery of the mapped multicast service flow to the particular subscriber device.

    摘要翻译: 在一个实施例中,处理设备耦合在互联网协议电视(IPTV)系统内的至少一个内容源与至少一个用户设备之间,以便从至少一个内容源接收多个服务流并处理多播 来自至少一个订户设备的服务流请求。 所述处理装置包括映射模块,用于基于来自特定用户设备的多播服务流请求将映射服务流从多播服务流映射到单播模块,以向所映射的多播服务流分配唯一标识符以转换 映射的多播服务流到映射的多播服务流的单播传递流向特定订户设备。