摘要:
A roller conveyor is disclosed that constitutes a conveying path with plural rollers arranged in parallel. The roller conveyor includes the plural rollers in alignment with one another on both sides of the conveying path, and a roller driving motor provided to each of the rollers. In the roller conveyor, the rollers are directly linked to rotary shafts of the corresponding roller driving motors.
摘要:
This invention provides a compound of the formula (I): wherein R1 represents a (C1–C6)alkyl group; R2 represents a hydrogen atom, a halogen atom, a hydroxy group, a (C1–C6)alkyl group or a (C1–C6)alkoxy group; R3, R4, R5 and R6 each independently represents a hydrogen atom, a (C1–C6)alkyl, or a halogen atom; R7 represents a hydrogen atom, a halogen atom, a hydroxy group, a (C1–C6)alkyl group optionally substituted with a piperidino group, a (C1–C6)alkoxy group optionally substituted with a 3–7 membered cycloalkyl ring, a hydroxy(C1–C6)alkoxy group, a (C1–C6)alkoxy-(C1–C6)alkyl group, a (C1–C6)alkoxy-(C1–C6)alkoxy group, a halo (C1–C6)alkyl group, a (C1–C6)alkylthio group, a (C1–C6)alkylsulfinyl group or a (C1–C6)alkylsulfonyl group; R8 represents a (C1–C6)alkyl group, a halo(C1–C6)alkyl group, a (C1–C6)alkoxy group, a hydroxy(C1–C6)alkoxy group, a (C1–C6)alkoxy-(C1–C6)alkyl group or a (C1–C6)alkoxy-(C1–C6)alkoxy group; or R7 and R8, when adjacent to each other, taken together with the carbon atoms to which they are attached form a 5–8 membered carbocyclic or heterocyclic ring, wherein the carbocyclic ring or the heterocyclic ring is unsubstituted or substituted with one or more substituents selected from the group consisting of a hydroxy group, a (C1–C6)alkyl group, a (C1–C6)alkoxy group and a hydroxy(C1–C6)alkyl group; and R9 represents a hydrogen atom or a halogen atom; or a pharmaceutically acceptable salt or solvate thereof. These compounds are useful for the treatment of disease conditions caused by overactivation of VR1 receptor, such as pain or the like in mammalian. The present invention also provides a pharmaceutical composition comprising the compound of formula(I).
摘要:
A clamp device includes a base, a X direction positioning pin positioning a work piece in a X direction, and a Y direction positioning pin positioning the work piece in a Y direction. A X direction arm moves the work piece toward the X direction positioning pin. A Y direction arm moves the work piece toward the Y direction positioning pin. An arm drive mechanism performs moving actuation of the X direction arm and moving actuation of the Y direction arm. The X direction arm and the Y direction arm are constructed such that the arm drive mechanism performs the moving actuation of the Y direction arm and the moving actuation of the X direction arm with a time difference being provided between the pressing of the work piece against the Y direction positioning pin and the pressing of the work piece against the X direction positioning pin.
摘要:
This invention provides a compound of the formula (I): wherein R1 represents (C1-C6)alkyl; R2 represents a hydrogen atom, a halogen atom, a hydroxy group, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkyl or halo(C1-C6)alkyl; R3 represents a halogen atom, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, halo(C1-C6)alkyl, (C1-C6)alkylthio, (C1-C6)alkylsulfinyl, (C1-C6)alkylsulfonyl, [(C1-C6)alkyl]NH—, or [(C1-C6)alkyl]2N—; R4 represents a halogen atom, (C1-C6)alkyl, halo(C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, [(C1-C6)alkyl]NH—, or [(C1-C6)alkyl]2N—; R5 represents a halogen atom, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, halo(C1-C6)alkyl, (C1-C6)alkylthio, (C1-C6)alkylsulfinyl, (C1-C6)alkylsulfonyl, [(C1-C6)alkyl]NH—, [(C1-C6)alkyl]2N—, H2N—(C1-C6)alkoxy, (C1-C6)alkyl-NH—(C1-C6)alkoxy, [(C1-C6)alkyl]2N(C1-C6)alkoxy, H2N—(C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkyl-NH—(C1-C6)alkoxy-(C1-C6)alkyl, or [(C1-C6)alkyl]2N(C1-C6)alkoxy-(C1-C6)alkyl; and * indicates a chiral centre; or a pharmaceutically acceptable salt or solvate thereof. These compounds are useful for the treatment of disease conditions caused by overactivation of VR1 receptor such of pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.
摘要:
A mechanism deck provided with a turntable for rotating a disk and movable upward or downward as coupled to a slide member comprises a subchassis having the turntable mounted thereon, and a frame fitting to the slide member and supporting the subchassis. The chassis is provided with a holding mechanism for upwardly or downwardly pivotally movably supporting the frame as fitted to the slide member through a space between the clamp support plate and the chassis. The frame is provided with a pin projecting outward therefrom and supported by the holding mechanism for restraining the frame from backlashing upward or downward, and the projecting pin has a projection for preventing the frame from backlashing laterally.
摘要:
An injection vessel including a glass cartridge; a rubber stopper (front stopper) and a rubber stopper (end stopper) respectively fitted to a front side and a rear side of the glass cartridge slidably in an axial direction of the glass cartridge in close contact with an inner face of the glass cartridge; a luer lock hub attached to the front end side of the glass cartridge in which a nozzle thereof is protruded outwardly; a finger grip attached to the rear end side of the glass cartridge; a plungerrod for pressing the rubber stopper (end stopper); a nozzle cap covering the nozzle; and wherein a collar consisting of a separate member is protruded equivalently or more than the nozzle or a collar portion with an elevated height attached directly to the luer lock hub is provided at a surrounding of the nozzle of the luer lock hub whereby a front end height of the collar portion is equivalent to or higher than a height of the nozzle.
摘要:
A Ni--Fe magnetic alloy consists essentially of:77 to 80 wt. % Ni, 3.5 to 5 wt. % Mo, 1.5 to 3 wt. % Cu, 0.1 to 1.1 wt. % Mn, 0.1 wt. % or less Cr, 0.003 wt. % or less S, 0.01 wt. % or less P, 0.005 wt. % or less O, 0.003 wt. % or less N, 0.02 wt. % or less C, 0.001 to 0.05 wt. % Al, 1 wt. % or less Si, 2.6-6 of the weight ratio of Ca to S, (Ca/S), and the balance being Fe and inevitable impurities, satisfies an equation of 3.2.ltoreq.(2.02.times.[Ni]-11.13.times.[Mo]-1.25.times.[Cu]-5.03.times.[Mn])/(2.13.times.[Fe]).ltoreq.3.8; and has a Mo segregation ratio defined by a seregration equation satisfying 5% or less, the seregration equation being .vertline.(Mo content in a segregation region-Mo average content)/(Mo average content).vertline..times.100%.A method for producing a magnetic Ni--Fe alloy comprises the steps of: a first heating step of heating an alloy ingot to 1200.degree. to 1300.degree. C. for 10 to 30 hrs; slabbing the heated ingot at a finishing temperature of 950.degree. C. or more to produce a slab; a second heating step of heating the slab at 1150.degree. to 1270.degree. C. for 1 to 5 hrs; and hot rolling the heated slab at a finishing temperature 950.degree. C. or more.
摘要:
A thin Fe--Ni alloy sheet for shadow mask consists essentially of Ni of 34 to 38 wt. %, Si of 0.05 wt. % or less, B of 0.0005 wt. % or less, O of 0.002 wt. % or less and N of 0.0015% or less, the balance being Fe and inevitable impurities; said alloy sheet after annealing before press-forming having 0.2% proof stress of 28.5 kgf/mm.sup.2 or less; and a degree of {211} plane on a surface of said alloy sheet being 16% or less. And further modified similar alloy sheets are also provided.Further, a method for producing a thin Fe--Ni alloy sheet for shadow mask comprises the steps of: (a) hot-rolling of a slab into a hot-rolled alloy strip; (b) hot-rolled sheet annealing of the hot-rolled strip at 910.degree. to 990.degree. C.; (c) cold-rolling of the annealed hot-rolled strip into a cold-rolled strip; (d) recrystallization annealing of the cold-rolled strip; (e) finish cold-rolling of the recrystallization annealed strip at a finish cold reduction ratio in response to austenite grain size D(D.mu.m) yielded by the recrystallization annealing, the finish cold reducration ratio(R) being within a region enclosed by a range of R of 16 to 75 and a range of D of 6.38D-133.9.ltoreq.R.ltoreq.6.38D-51.0 and (f) annealing of the finish cold-rolled strip on conditions of a temperature of 720.degree. to 790.degree. C., a time of 2 to 40 min. and T.gtoreq.-53.8 logt+806, where T(.degree.C.) is the temperature of the annealing. And further modified similar methods are also provided.
摘要:
A thin Fe--Ni alloy sheet for shadow mask consists essentially of Ni of 34 to 38 wt. %, Si of 0.05 wt. % or less, B of 0.0005 wt. % or less, O of 0.002 wt. % or less and N of 0.0015% or less, the balance being Fe and inevitable impurities; said alloy sheet after annealing before press-forming having 0.2% proof stress of 28.5 kgf/mm or less; and a degree of {211 } plane on a surface of said alloy sheet being 16% or less. And further modified similar alloy sheets are also provided.Further, a method for producing a thin Fe--Ni alloy sheet for shadow mask comprises the steps of: (a) hot-rolling of a slab into a hot-rolled alloy strip; (b) hot-rolled sheet annealing of the hot-rolled strip at 910.degree. to 990.degree. C.; (c) cold-rolling of the annealed hot-rolled strip into a cold-rolled strip; (d) recrystallization annealing of the cold-rolled strip; (e) finish cold-rolling of the recrystallization annealed strip at a finish cold reduction ratio in response to austenite grain size D(D .mu.m) yieleded by the recrystallization annealing, the finish cold reducration ratio(R) being within a region enclosed by a range of R of 16 to 75 and a range of D of 6.38D-133.9.ltoreq.R.ltoreq.6.38D-51.0 and (f) annealing of the finish cold-rolled strip on conditions of a temperature of 720.degree. to 790.degree. C., a time of 2 to 40 min. and T.ltoreq.-53.8 logt+806, where T(.degree.C.) is the temperature of the annealing. And further modified similar methods are also provided.
摘要:
A continuous mixer system for controlling the saccharide concentration of a sweetened liquid product mixture, which has (i) an undiluted sweetened solution input, (ii) a water input, (iii) a mixer having a product output, (iv) a first positive displacement rotary pump having a speed of rotation for feeding an undiluted sweetened solution through the undiluted sweetened solution input, (v) a second positive displacement rotary pump having a speed of rotation for feeding water through the water input, (vi) a continuous saccharometer for detecting the saccharide concentration of the product mixture discharged through the product output, (vii) a first speed adjuster for adjusting the rotational speed of said first rotary pump, (viii) a second speed adjuster for adjusting the rotational speed of the second rotary pump; and (ix) a controller, wherein a target value SB.sub.x of the saccharide concentration at the product output is preset in the controller and an actual value XB.sub.x detected by the saccharometer at the product output is compared in the controller with the target value SB.sub.x, the first and second speed adjusters can change the speeds of rotation of the first and the second pumps to reduce any difference found between SB.sub.x and XG.sub.x.