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    Anti-2-O-desulfated acharan sulfate antibody and its application
    32.
    发明授权
    Anti-2-O-desulfated acharan sulfate antibody and its application 有权
    抗-2-O-脱硫酸阿卡拉酸硫酸抗体及其应用

    公开(公告)号：US08158365B2

    公开(公告)日：2012-04-17

    申请号：US12297047

    申请日：2007-04-27

    Applicant: Kiyoshi Suzuki ,  Takeshi Ishimaru ,  Koji Yamamoto ,  Yeong Shik Kim

    Inventor： Kiyoshi Suzuki ,  Takeshi Ishimaru ,  Koji Yamamoto ,  Yeong Shik Kim

    IPC: G01N33/53 ,  C07K16/18 ,  C07K16/44 ,  C12P21/08

    CPC classification number: C07K16/44

    Abstract: An antibody that reacts with 2-O-desulfated acharan sulfate, a hybridoma that produces the antibody, a detection method and a detection kit to which the antibody is applied are disclosed. The antibody that reacts with 2-O-desulfated acharan sulfate can be produced by immunizing a mammal using as an antigen a substance obtained by chemically bonding a protein to 2-O-desulfated acharan sulfate.

    Abstract translation: 公开了与2-O-脱硫酸阿卡拉酸硫酸反应的抗体，产生抗体的杂交瘤，检测方法和应用抗体的检测试剂盒。 与2-O-脱硫酸阿沙拉硫酸盐反应的抗体可以通过使用通过化学键合蛋白质获得的物质作为抗原免疫哺乳动物来制备，所述物质通过将化学键合到2-O-脱硫酸阿卡拉酸硫酸酯。

    METHOD FOR ASSAYING KERATAN SULFATE, ASSAY KIT THEREFOR AND METHOD FOR DETECTING JOINT DISEASE BY USING THE SAME
    33.
    发明申请
    METHOD FOR ASSAYING KERATAN SULFATE, ASSAY KIT THEREFOR AND METHOD FOR DETECTING JOINT DISEASE BY USING THE SAME 有权
    用于测定硫酸钙的方法，其测定工具及其使用方法检测联合疾病

    公开(公告)号：US20110318759A1

    公开(公告)日：2011-12-29

    申请号：US13142262

    申请日：2009-12-24

    Applicant: Shigeyuki Wakitani ,  Hiroshi Fujita ,  Takeshi Ishimaru ,  Koji Yamamoto ,  Yasuhiro Kurahashi ,  Junichi Onaya ,  Hiroyuki Masuda

    Inventor： Shigeyuki Wakitani ,  Hiroshi Fujita ,  Takeshi Ishimaru ,  Koji Yamamoto ,  Yasuhiro Kurahashi ,  Junichi Onaya ,  Hiroyuki Masuda

    IPC: G01N33/577 ,  C07K16/18

    CPC classification number: G01N33/53 ,  G01N2400/40 ,  G01N2800/102

    Abstract: The inventions provides a method for immunologically determining a keratan sulfate level which method includes bringing an anti-keratan sulfate monoclonal antibody into contact with a biological sample, the anti-keratan sulfate monoclonal antibody exhibiting a relative reaction specificity between keratan sulfate-I and keratan sulfate-II represented by IC50KS-I/KS-II of 0.4 to 5, to thereby provide a signal; and detecting keratan sulfate contained in the biological sample from the signal. On the basis of the method, the invention also provides a joint disease detection method and a method for assessing the effect of a remedy for a joint disease and a candidate substance therefor. Through these methods, a very small amount of keratan sulfate contained in a sample, can be determined. Particularly, these methods can determine, at high-sensitivity and high-specificity, the total keratan sulfate including keratan sulfate-I, which have been difficult to determine through a conventional technique. The methods also enables detect a joint disease and assess the effect of a remedy for a joint disease or a candidate substance therefor.

    Abstract translation: 本发明提供了一种免疫测定硫酸角质素水平的方法，该方法包括使硫酸角质素硫酸单克隆抗体与生物样品接触，硫酸角质素-I与硫酸角质素之间呈现相对反应特异性的硫酸角质素单体抗体 -II由IC50KS-I / KS-II表示，为0.4〜5，从而提供信号; 并从信号中检测生物样品中所含的硫酸角质素。 在该方法的基础上，本发明还提供了关于联合疾病的检测方法和评估对于关节疾病及其候选物质的补救效果的方法。 通过这些方法，可以测定样品中所含的极少量硫酸角质素。 特别地，这些方法可以高灵敏度和高特异性地确定通过常规技术难以确定的总硫酸角质素，包括硫酸角质素-I。 该方法还能够检测关节疾病并评估对于关节疾病或候选物质的补救的效果。

    PARTICULATE SUBSTANCE FOR FILLING ARTIFICIAL TURF AND ARTIFICIAL TURF STRUCTURE FILLED WITH THE PARTICULATE SUBSTANCE FOR FILLING ARTIFICIAL TURF
    34.
    发明申请
    PARTICULATE SUBSTANCE FOR FILLING ARTIFICIAL TURF AND ARTIFICIAL TURF STRUCTURE FILLED WITH THE PARTICULATE SUBSTANCE FOR FILLING ARTIFICIAL TURF 审中-公开
    用于填充人造血液的人造血液和人造血液结构的颗粒物质填充与颗粒物质填充人造血液

    公开(公告)号：US20110189408A1

    公开(公告)日：2011-08-04

    申请号：US12808352

    申请日：2008-11-28

    Applicant: Takeshi Ishimaru ,  Hideyuki Okuyama

    Inventor： Takeshi Ishimaru ,  Hideyuki Okuyama

    IPC: A41G1/00 ,  B32B5/16

    CPC classification number: E01C13/08 ,  Y10T428/2982

    Abstract: A recycling technique for long-pile artificial turfs is provided in which a spent artificial turf is recycled and formed into an elastic particulate substance suitable for use as a filler for long-pile artificial turfs. The particulate substance (5), with which the space among the piles (4) of an artificial turf (3) is filled, is obtained by using as a raw material an artificial turf comprising at least 50 wt. % thermoplastic resin, adding an elastomer to the raw material, and forming the resultant mixture into particles. The particulate substance (5) has a specific gravity regulated to 1.10 or higher and is used for the filling.

    Abstract translation: 提供了长桩人造草皮的回收技术，其中废弃的人造草被再循环并形成为适合用作长桩人造草皮填料的弹性颗粒物质。 通过使用包含至少50重量％的人造草皮作为原料，获得填充人造草皮（3）的桩（4）之间的空间的颗粒物质（5）。 ％热塑性树脂，向原料中加入弹性体，并将所得混合物形成颗粒。 颗粒物质（5）的比重为1.10以上，用于填充。

    Light guide having reflective protruding portion, and lighting devices including such light guide
    35.
    发明授权
    Light guide having reflective protruding portion, and lighting devices including such light guide 失效
    具有反射性突出部的导光体以及包含该导光体的照明装置

    公开(公告)号：US07942561B2

    公开(公告)日：2011-05-17

    申请号：US12087549

    申请日：2006-12-27

    Applicant: Takeshi Ishimaru ,  Takashi Kishimoto ,  Hidemitsu Takeuchi ,  Tomihisa Saito ,  Hideki Azuma ,  Takahiro Hashimoto

    Inventor： Takeshi Ishimaru ,  Takashi Kishimoto ,  Hidemitsu Takeuchi ,  Tomihisa Saito ,  Hideki Azuma ,  Takahiro Hashimoto

    IPC: F21V7/04

    CPC classification number: G02B6/0055 ,  G03B27/54 ,  H04N1/02815 ,  H04N1/02835 ,  H04N1/0289 ,  H04N2201/02487 ,  H04N2201/02493

    Abstract: A rod- or plate-shaped light guide includes a first end that receives illuminating light incident thereon, a bottom surface having a reflecting portion thereon for reflecting the light, an emitting face which emits the reflected light, and a protruding portion protruding longitudinally and continuously from the light guide at a second end thereof. The protruding portion has a reduced peripheral dimension compared to a peripheral dimension of an adjacent portion of the light guide, and a reflective body is provided on the protruding portion and covers a longitudinal end face of the protruding portion extending perpendicular to the emitting face. When viewed along an axial direction of the light guide, the reflective body does not jut out from an end face of the light guide even when the body wraps on to a side surface of the protruding portion or expansion occurs.

    Abstract translation: 棒状或板状的导光体包括：第一端，其接收入射的照明光;底面，其上具有用于反射光的反射部，发射反射光的发射面;以及突出部， 在其第二端处的光导。 与导光体的相邻部分的周边尺寸相比，突出部分具有减小的外围尺寸，并且反射体设置在突出部分上并且覆盖垂直于发射面延伸的突出部分的纵向端面。 当沿着导光体的轴向方向观察时，即使当身体卷绕到突出部分的侧表面或发生膨胀时，反射体也不会从光导的端面突出。

    Light guide and image reader
    38.
    发明申请
    Light guide and image reader 有权
    光导和图像阅读器

    公开(公告)号：US20090218525A1

    公开(公告)日：2009-09-03

    申请号：US11920302

    申请日：2006-04-28

    Applicant: Makoto Ikeda ,  Hiroyuki Nemoto ,  Takashi Kishimoto ,  Takeshi Ishimaru ,  Hirohiko Iwase ,  Hidemitsu Takeuchi ,  Tomihisa Saito

    Inventor： Makoto Ikeda ,  Hiroyuki Nemoto ,  Takashi Kishimoto ,  Takeshi Ishimaru ,  Hirohiko Iwase ,  Hidemitsu Takeuchi ,  Tomihisa Saito

    IPC: H04N1/04 ,  F21V8/00

    CPC classification number: G03B27/54 ,  G02B6/0036 ,  G02B6/0038 ,  H04N1/02815 ,  H04N1/02835 ,  H04N1/02885 ,  H04N1/0289 ,  H04N1/0318 ,  H04N2201/02487 ,  H04N2201/03112 ,  H04N2201/03125 ,  H04N2201/03129 ,  H04N2201/03141 ,  H04N2201/03145 ,  H04N2201/03183

    Abstract: A rod-shaped light guide which does not cause unevenness in color at the portion near an incident face is produced by injection-molding transparent resin such as acryl and its surfaces include a light-emitting surface, a bottom face, left and right sides and end faces. One end face opposes a light emitting unit, and light scattering patterns for scattering light incident from the end face are formed on the bottom face. The light scattering patterns are different in shape between a portion near the end face as the incident face and a portion away from the end face. The light scattering patterns formed at the portion near the incident face are composed of a large number of fine hemispherical concaves, whereas the light scattering patterns at the portion away from the incident face are composed of triangular grooves or half cylindrical grooves, and the axial direction of these triangular grooves or half cylindrical grooves is equal to coincides with the width direction (sub-scanning direction) of the bottom face on which the patterns are formed.

    Abstract translation: 在入射面附近部分不会引起颜色不均的棒状导光体是通过注射成型的透明树脂如丙烯酸而形成的，其表面包括发光面，底面，左右两侧， 端面。 一个端面与发光单元相对，并且在底面上形成用于散射从端面入射的光的光散射图案。 光散射图案在作为入射面的端面附近的部分和远离端面的部分之间的形状不同。 在入射面附近形成的光散射图案由大量的细半球形凹部构成，而远离入射面的部分的光散射图案由三角形槽或半圆柱形槽构成，轴向方向 这些三角形槽或半圆柱形槽的长度方向与形成有图案的底面的宽度方向（副扫描方向）一致。

    Line Lighting Device and Image Reading Device
    40.
    发明申请
    Line Lighting Device and Image Reading Device 有权
    线路照明设备和图像读取设备

    公开(公告)号：US20090003000A1

    公开(公告)日：2009-01-01

    申请号：US12087403

    申请日：2006-12-22

    Applicant: Tomihisa Saito ,  Hidemitsu Takeuchi ,  Takeshi Ishimaru

    Inventor： Tomihisa Saito ,  Hidemitsu Takeuchi ,  Takeshi Ishimaru

    IPC: F21V3/00

    CPC classification number: H04N1/02815 ,  G02B6/003 ,  G02B6/0088 ,  G03B27/54 ,  H04N1/02835 ,  H04N1/0284 ,  H04N1/1017 ,  H04N1/193 ,  H04N2201/02462 ,  H04N2201/02474 ,  H04N2201/02481 ,  H04N2201/02485 ,  H04N2201/03112 ,  H04N2201/03125 ,  H04N2201/03141 ,  H04N2201/03145

    Abstract: A structure of a line lighting device permits a rod-like light guide to be attached to a case without rubbing against the case. An end portion of the rod-like light guide provided with a pin is inserted into an opening in a case main body and pushed down, thus making the pin engage with a recess in the case main body. At this time, a distal end of the rod-like light guide is inserted, to some extent, into an opening in a light emitting unit fixing portion. Subsequently, the rod-like light guide is pushed down and pivoted around the pin so as to be completely contained within the case main body. In this state, the distal end of the rod-like light guide is fitted into the opening and the end face of the rod-like light guide is flush with the outer side face of the light emitting unit fixing portion.

    Abstract translation: 线照明装置的结构允许棒状光导被附着到壳体而不会碰到外壳。 设置有销的棒状光导体的端部插入到壳体主体的开口中并向下推动，从而使销与壳体主体中的凹部接合。 此时，杆状导光体的远端在一定程度上插入发光单元固定部的开口部。 随后，杆状光导被推下并围绕销枢转，以便完全容纳在壳体主体内。 在该状态下，棒状导光体的前端嵌入开口部，杆状导光体的端面与发光单元固定部的外侧面齐平。

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