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123 条记录 (耗时 0.032 秒)

    Method and systems for establishing vascular access
    31.
    发明授权
    Method and systems for establishing vascular access 失效
    建立血管通路的方法和系统

    公开(公告)号：US06258079B1

    公开(公告)日：2001-07-10

    申请号：US09333828

    申请日：1999-06-15

    申请人： Jeffrey H. Burbank ,  James M. Brugger ,  Charles D. Finch ,  Gerald Beathard ,  George W. Buffaloe

    发明人： Jeffrey H. Burbank ,  James M. Brugger ,  Charles D. Finch ,  Gerald Beathard ,  George W. Buffaloe

    IPC分类号： A61M3100

    CPC分类号： A61M1/3653 ,  A61M1/3659 ,  A61M5/158 ,  A61M25/0023 ,  A61M39/0208 ,  A61M2005/1581 ,  A61M2205/195

    摘要： A body lumen access system comprises a distal access cannula and a proximal access cannula. The distal access cannula is attached to or within the body lumen and the proximal access cannula is attached to an implantable port or is transcutaneously positioned and attached to a luer or other external connector. The distal and proximal access cannulas are usually implanted separately, cut to length, and attached at a subcutaneous junction location. Preferably, the proximal access cannula has a larger lumen diameter than that of the distal access cannula in order to reduce flow resistance within the cannula system. In some cases the distal and proximal access cannulas may be formed integrally. Replacement of a proximal portion or distal end may be performed by accessing the cannula, removing either the proximal portion or distal end, and reattaching a replacement portion of the cannula.

    摘要翻译： 体腔通道系统包括远端进入插管和近端通路套管。 远端进入插管附接到体腔内或体腔内，并且近侧进入插管附接到可植入端口，或经皮定位并附接到鲁尔或其它外部连接器。 远端和近端通道插管通常单独植入，切割长度，并连接在皮下接合处。 优选地，近侧通路插管具有比远侧进入插管更大的内腔直径，以便减小套管系统内的流动阻力。 在一些情况下，远端和近侧通路插管可以一体形成。 近端部分或远端的替换可以通过进入插管，移除近端部分或远端以及重新附接插管的置换部分来执行。

    Device for percutaneous peritoneal dialysis
    32.
    发明授权
    Device for percutaneous peritoneal dialysis 失效
    用于经皮腹膜透析的装置

    公开(公告)号：US06193684B1

    公开(公告)日：2001-02-27

    申请号：US08896791

    申请日：1997-07-18

    申请人： Jeffrey H. Burbank ,  James M. Brugger

    发明人： Jeffrey H. Burbank ,  James M. Brugger

    IPC分类号： A61M100

    CPC分类号： A61M1/3653 ,  A61M1/28 ,  A61M1/285 ,  A61M1/3659 ,  A61M1/3661 ,  A61M25/0023 ,  A61M39/0208 ,  A61M39/26 ,  A61M2205/195

    摘要： The present invention is generally directed to delivering liquid compositions to an interior site in the body. More particularly, the present invention provides devices, systems, and methods for facilitating percutaneous access to an implantable port for performing peritoneal dialysis in a sterile condition. In one aspect, the present invention provides an apparatus for use in peritoneal dialysis comprising a first container and a second container, wherein at least one of the containers is filled with unused dialysis fluid. The first and second containers are fluidly coupled by a first tube and a second tube to a junction, respectively. A single common tube fluidly coupled to the junction provides a fluid pathway to a percutaneous access member connected to the end of the single common tube. The access member has a minimum bore diameter of 1.16 mm capable of providing high volumetric flow rates.

    摘要翻译： 本发明一般涉及将液体组合物输送到体内的内部部位。 更具体地，本发明提供了用于促进经皮进入可植入端口以用于在无菌状况下进行腹膜透析的装置，系统和方法。 一方面，本发明提供了一种用于腹膜透析的装置，其包括第一容器和第二容器，其中至少一个容器填充有未使用的透析液。 第一和第二容器分别通过第一管和第二管流体连接到结。 流体耦合到连接处的单个公共管提供到连接到单个公共管的端部的经皮进入构件的流体路径。 进入构件的最小孔径为1.16mm，能够提供高体积流量。

    Dialysis blood tubing set
    33.
    发明授权
    Dialysis blood tubing set 失效
    透析血管套装

    公开(公告)号：US5693008A

    公开(公告)日：1997-12-02

    申请号：US480856

    申请日：1995-06-07

    申请人： James M. Brugger ,  Keith J. Manica ,  William G. Palsulich

    发明人： James M. Brugger ,  Keith J. Manica ,  William G. Palsulich

    IPC分类号： A61M1/14 ,  A61M1/36 ,  A61M37/00

    CPC分类号： A61M1/3639 ,  A61M1/3641

    摘要： A combination pressure pod and access site apparatus is suitable for use in a medical tubing set. The combination pressure pod and access site comprises a pressure sensing chamber and a measured fluid chamber separated by a pressure transmissive diaphragm. An access site having a needle or needle-less septum is in fluid communication with the measured fluid chamber and permits and withdrawing fluids from, the measured fluid chamber through the access site. One or more of the combination pressure sites and access sites may be provided in a simplified blood tubing set for an extracorporeal blood treatment apparatus, such as a hemodialysis apparatus.

    摘要翻译： 组合压力舱和进入现场设备适用于医疗管道组。 组合压力舱和进入位置包括压力感测室和由压力传递隔膜隔开的测量流体室。 具有针或无针孔隔膜的进入位置与所测量的流体室流体连通，并且允许通过进入位置从所测量的流体室排出流体。 组合压力部位和进入部位中的一个或多个可以在诸如血液透析装置的体外血液处理装置的简化血管组中提供。

    Differential conductivity hemodynamic monitor
    34.
    发明授权
    Differential conductivity hemodynamic monitor 失效
    差分电导率血液动力学监测仪

    公开(公告)号：US5644240A

    公开(公告)日：1997-07-01

    申请号：US486982

    申请日：1995-06-07

    申请人： James M. Brugger

    发明人： James M. Brugger

    IPC分类号： A61M1/16 ,  A61M1/36 ,  G01F1/704 ,  G01F1/708 ,  G01N27/02 ,  G01N33/487 ,  G01N27/08 ,  G01P5/08

    CPC分类号： A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3658 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

    摘要： A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it take to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.

    摘要翻译： 在管中流动的流体的流速通过注射大量盐水改变流体的电导率而定量地确定。 在改变的导电流体通过电导率测量位置的时间内测量改变的导电性的导电性。 测量的电导率在通过电导率测量位置所需的时间内积分。 积分被解释为确定流量。

    Hemodynamic monitor for detecting air bubbles
    35.
    发明授权
    Hemodynamic monitor for detecting air bubbles 失效
    用于检测气泡的血液动力学监测器

    公开(公告)号：US5631552A

    公开(公告)日：1997-05-20

    申请号：US472268

    申请日：1995-06-07

    申请人： Francis T. Ogawa ,  James M. Brugger

    发明人： Francis T. Ogawa ,  James M. Brugger

    IPC分类号： A61M1/16 ,  A61M1/36 ,  G01F1/704 ,  G01F1/708 ,  G01N27/02 ,  G01N33/487 ,  G01N27/06

    CPC分类号： G01F1/7088 ,  A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3658 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708

    摘要： The presence of air bubbles entrained in a liquid flowing through a tube is detected flowing the liquid through a conduit which comprises a conductivity cell with a continuous path configuration. An electrical current is induced in the liquid in the conductivity cell. The electrical current in the liquid in the conductivity cell is sensed and interpreted, a decrease in the electrical current being indicative of the presence of an air bubble in the liquid. The conductivity cell comprises an upstream connection, a downstream connection, and two branches connecting the upstream connection to the downstream connection with a continuous path configuration from the upstream connection to the downstream connection through one of the two branches and returning to the upstream connection through the other one of the two branches.

    摘要翻译： 检测到夹带在流过管的液体中的气泡的存在使液体流过包括具有连续路径构造的电导池的导管。 在电导池中的液体中产生电流。 感测和解释导电池中的液体中的电流，电流的减小表示液体中存在气泡。 电导率单元包括上游连接，下游连接以及将上游连接与下游连接相连接的两个分支，其具有从上游连接到通过两个分支之一的下游连接的连续路径配置，并返回到上游连接 另外两个分支之一。

    Side flow bubble trap apparatus and method
    36.
    发明授权
    Side flow bubble trap apparatus and method 失效
    侧流式气泡捕集装置及方法

    公开(公告)号：US5591251A

    公开(公告)日：1997-01-07

    申请号：US362262

    申请日：1994-12-22

    申请人： James M. Brugger

    发明人： James M. Brugger

    IPC分类号： A61M1/36 ,  B01D9/00 ,  A61M1/14 ,  A61M3/00

    CPC分类号： A61M1/3627 ,  A61M2205/7545

    摘要： An apparatus for trapping bubbles in blood flowing in a circuit, such as an extracorporeal circuit, includes a housing which defines a substantially vertical chamber having an upper subchamber and a lower subchamber. Blood flowing in a substantially downward direction is introduced into the upper subchamber chamber through a delivery port in a direction substantially transverse to a longitudinal axis of the upper subchamber. A substantially frustoconical deflector is positioned in the chamber opposite and spaced apart from the delivery port. The deflector deflects at least a portion of the blood into the upper subchamber above the deflector. Thereafter, the blood is removed from the chamber out an exit port of the chamber. The deflection and redirection of blood within the chamber provide an opportunity for gases in the blood to separate from the blood in the chamber and also helps prevent stagnation of blood in the chamber which might lead to clotting of the blood. A method of removing bubbles from blood flowing in a circuit involves introducing blood into a substantially vertical chamber at an angle substantially transverse to a longitudinal vertical axis of the chamber. At least a portion of the blood is deflected upward in the chamber by contact with a frustoconical deflector to allow gases to separate from the blood. The blood is then removed from the chamber.

    摘要翻译： 用于在诸如体外电路的电路中流动的血液中捕获气泡的装置包括限定具有上部副室和下部子室的基本上垂直的室的壳体。 以基本上向下的方向流动的血液通过输送口沿基本上横向于上部副室的纵向轴线的方向被引入上部空间室。 大致截头圆锥形偏转器位于腔室中，与输送口相对并间隔开。 偏转器将至少一部分血液偏转到偏转器上方的上部子室中。 此后，血液从腔室的出口移出。 血液在腔室内的偏转和重定向提供了血液中的气体与腔室中的血液分离的机会，并且还有助于防止腔室中的血液停滞，这可能导致血液凝结。 从在血液循环中流动的血液中除去气泡的方法包括将血液以基本上横向于腔室的纵向垂直轴线的角度引入基本垂直的腔室。 至少一部分血液通过与截头圆锥形偏转器接触而在腔室中向上偏转，以允许气体与血液分离。 然后将血液从腔室中取出。

    Altered fluid conductivity monitor
    37.
    发明授权
    Altered fluid conductivity monitor 失效
    改变流体电导率监测器

    公开(公告)号：US5570026A

    公开(公告)日：1996-10-29

    申请号：US455349

    申请日：1995-05-31

    申请人： George W. Buffaloe, IV ,  Francis T. Ogawa ,  James M. Brugger

    发明人： George W. Buffaloe, IV ,  Francis T. Ogawa ,  James M. Brugger

    IPC分类号： G01N27/06 ,  A61M1/14 ,  A61M1/16 ,  A61M1/36 ,  G01F1/704 ,  G01F1/708 ,  G01N27/02 ,  G01N33/487 ,  G01R27/02 ,  G01N27/08

    CPC分类号： G01F1/7088 ,  A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3658 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708

    摘要： A differential conductivity recirculation monitor quantitatively determines the degree of recirculation in a fistula by comparing the conductivity of blood entering the fistula to the conductivity of blood being withdrawn from the fistula. A discrete quantity of a high conductivity marker fluid is injected into the blood entering the fistula, altering the conductivity of the blood entering the fistula. The altered conductivity blood enters the fistula and, if recirculation is present, co-mingles with blood in the fistula, altering the conductivity of the blood in the fistula in proportion to the degree of recirculation. Blood withdrawn from the fistula has an altered conductivity related to the degree of recirculation. Quantitative values of the conductivity of the altered conductivity blood entering the fistula and the conductivity of the blood being withdrawn from the fistula are measured and a difference determined. The determined difference between the conductivities is used to determine a quantitative measurement of the degree of recirculation in the fistula.

    摘要翻译： 差分电导率再循环监测器通过比较进入瘘的血液的电导率与从瘘管抽取的血液的电导率来定量地确定瘘管中的再循环程度。 将离散量的高电导率标记液注入进入瘘管的血液中，改变进入瘘管的血液的电导率。 改变的电导率血液进入瘘管，如果存在再循环，则与瘘管中的血液共混，根据再循环程度改变瘘管中的血液的电导率。 从瘘管中取出的血液与再循环程度相关的导电性改变。 测量进入瘘的改变的导电性血液的导电性的定量值和从瘘管取出的血液的电导率，并确定差异。 电导率之间的确定差异用于确定瘘管再循环程度的定量测量。