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    Methods, devices, and systems for hemodilution
    4.
    发明授权
    Methods, devices, and systems for hemodilution 有权
    用于血液稀释的方法，装置和系统

    公开(公告)号：US07776219B2

    公开(公告)日：2010-08-17

    申请号：US12015420

    申请日：2008-01-16

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Martin Stillig

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Martin Stillig

    IPC分类号： B01D61/00 ,  B01D61/14 ,  B01D61/24 ,  B01D61/28 ,  A61M1/18 ,  A61M1/34

    CPC分类号： B01D63/02 ,  A61M1/342 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3672 ,  B01D61/20 ,  B01D61/30 ,  B01D2313/21

    摘要： Devices, methods, and system that prevent clotting of blood during blood-processing procedures such as hemofiltration, hemodialysis, and hemodiafiltration are described. A filter with a cap has a housing that is shaped to receive a blood filter. The housing has an inlet for blood and may have an outlet for waste and ultrafiltrate. The cap is attached to the housing. The cap has an outlet for blood and a port adjacent the outlet for receiving dilution fluid. Methods of use during blood-processing procedures to provide immediate hemodilution to blood exiting entering and/or exiting a filter are also described.

    摘要翻译： 描述了在血液过滤，血液透析和血液透析过滤等血液处理过程中防止血液凝结的装置，方法和系统。 具有帽的过滤器具有被成形为接收血液过滤器的壳体。 外壳有血液入口，可能有废物和超滤的出口。 盖子连接到外壳。 盖具有用于血液的出口和邻近出口的用于接收稀释液的口。 还描述了在血液处理过程中为进入和/或离开过滤器的血液立即进行血液稀释的使用方法。

    WASTE BALANCING FOR EXTRACORPOREAL BLOOD TREATMENT SYSTEMS
    5.
    发明申请
    WASTE BALANCING FOR EXTRACORPOREAL BLOOD TREATMENT SYSTEMS 有权
    用于超临界血液治疗系统的废物平衡

    公开(公告)号：US20100016777A1

    公开(公告)日：2010-01-21

    申请号：US12536412

    申请日：2009-08-05

    申请人： Jeffrey H. Burbank ,  James M. Brugger

    发明人： Jeffrey H. Burbank ,  James M. Brugger

    IPC分类号： A61M1/14

    CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M1/1611 ,  A61M1/1643 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3382 ,  A61M2205/3386 ,  A61M2205/50 ,  A61M2205/52

    摘要： One or more waste balancing systems may be used in a fluid circulating system for medical use. The fluid circulating system may be part of a blood treatment system for a patient suffering renal failure. A waste balancing system may include a pressure element operable to maintain a constant fluid pressure created by the combined weight of waste removed from a patient and replacement fluid for providing to a patient. Multiple evaluation characteristics or control parameters may be evaluated or controlled for safety and accuracy. At least part of the waste balancing system may be incorporated into a disposable cartridge.

    摘要翻译： 在用于医疗用途的流体循环系统中可以使用一个或多个废物平衡系统。 流体循环系统可以是患有肾衰竭的患者的血液处理系统的一部分。 废物平衡系统可以包括压力元件，其可操作以保持由从患者移除的废物的组合重量产生的恒定的流体压力和用于提供给患者的替换流体。 可以评估或控制多个评估特性或控制参数的安全性和准确性。 废物平衡系统的至少一部分可以结合到一次性盒中。

    Batch Filtration System for Preparation of Sterile Fluid for Renal Replacement Therapy
    6.
    发明申请
    Batch Filtration System for Preparation of Sterile Fluid for Renal Replacement Therapy 有权
    用于肾脏替代治疗的无菌液的制备过滤系统

    公开(公告)号：US20090211975A1

    公开(公告)日：2009-08-27

    申请号：US12434246

    申请日：2009-05-01

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    IPC分类号： B01D61/30 ,  B01D61/24 ,  B01D61/26

    CPC分类号： A61M1/1656 ,  A61M1/14 ,  A61M1/166 ,  A61M1/167 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/28 ,  A61M1/288 ,  A61M1/3462 ,  A61M2205/12 ,  C02F1/44

    摘要： A method and device for blood treatments that use fluids such as dialysate and replacement fluid for renal replacement therapy. In an embodiment, fluid is passed either by pump or passively by gravity feed, through a microporous sterilization filter from a fluid source to a replacement fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment. As a result, the sterilization filter can have a small capacity. In another embodiment, a filter is placed immediately prior to the point at which the sterile fluid is consumed by the treatment process. The latter may be used in combination with the former embodiment as a last-chance guarantee of sterility and/or that the fluid is free of air bubbles. It may also be used as the primary means of sterile-filtration.

    摘要翻译： 用于血液处理的方法和装置，其使用诸如透析液和替代液的流体用于肾替代治疗。 在一个实施例中，流体通过泵或被动地通过重力进料通过微孔灭菌过滤器从流体源传递到替换流体容器。 后者形成可在治疗期间使用的批次。 在处理之前形成批次的优点是过滤速率与处理过程中的消耗速率不一致。 结果，灭菌过滤器可以具有小容量。 在另一个实施方案中，过滤器被立即放置在无菌流体被处理过程消耗的点之前。 后者可以与前一个实施方案组合使用，作为不育的最后机会保证和/或流体没有气泡。 它也可以用作无菌过滤的主要手段。

    Batch filtration system for preparation of sterile fluid for renal replacement therapy
    8.
    发明授权
    Batch filtration system for preparation of sterile fluid for renal replacement therapy 有权
    用于制备用于肾替代治疗的无菌液体的分批过滤系统

    公开(公告)号：US07544300B2

    公开(公告)日：2009-06-09

    申请号：US11160764

    申请日：2005-07-07

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    IPC分类号： B01D61/30 ,  B01D61/00

    CPC分类号： A61M1/1656 ,  A61M1/14 ,  A61M1/166 ,  A61M1/167 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/28 ,  A61M1/288 ,  A61M1/3462 ,  A61M2205/12 ,  C02F1/44

    摘要： A method and device for blood treatments that use fluids such as dialysate and replacement fluid for renal replacement therapy. In an embodiment, fluid is passed either by pump or passively by gravity feed, through a microporous sterilization filter from a fluid source to a replacement fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment. As a result, the sterilization filter can have a small capacity. In another embodiment, a filter is placed immediately prior to the point at which the sterile fluid is consumed by the treatment process. The latter may be used in combination with the former embodiment as a last-chance guarantee of sterility and/or that the fluid is free of air bubbles. It may also be used as the primary means of sterile-filtration.

    摘要翻译： 用于血液处理的方法和装置，其使用诸如透析液和替代液的流体用于肾替代治疗。 在一个实施例中，流体通过泵或被动地通过重力进料通过微孔灭菌过滤器从流体源传递到替换流体容器。 后者形成可在治疗期间使用的批次。 在处理之前形成批次的优点是过滤速率与处理过程中的消耗速率不一致。 结果，灭菌过滤器可以具有小容量。 在另一个实施方案中，过滤器被立即放置在无菌流体被处理过程消耗的点之前。 后者可以与前一个实施方案组合使用，作为不育的最后机会保证和/或流体没有气泡。 它也可以用作无菌过滤的主要手段。

    Pressure detector for fluid circuits
    9.
    发明授权
    Pressure detector for fluid circuits 有权
    流体回路压力检测器

    公开(公告)号：US07337674B2

    公开(公告)日：2008-03-04

    申请号：US11160586

    申请日：2005-06-29

    申请人： Jeffrey H. Burbank ,  James M. Brugger ,  Dennis M. Treu ,  Christopher McDowell

    发明人： Jeffrey H. Burbank ,  James M. Brugger ,  Dennis M. Treu ,  Christopher McDowell

    IPC分类号： G01L7/00

    CPC分类号： G01L7/024 ,  A61M1/3639

    摘要： A pressure measurement device usable for monitoring pressure of fluids such as blood, waste, and replacement fluid in a blood treatment system provides a reliable signal and other benefits by virtue of a number of features of the various embodiments disclosed. The pressure of fluid carried by a vessel or tube is measured by measuring a change in shape of the vessel or tube via a sensor element contacting it. Materials, shape, and mechanical support cooperatively ensure that the little inelastic strain occurs and pressure measurements are repeatable. The embodiments are compatible with the use of disposable vessels and tubes.

    摘要翻译： 可用于监测血液处理系统中的血液，废物和置换液体等流体的压力的压力测量装置由于所公开的各种实施方式的许多特征而提供可靠的信号和其他益处。 容器或管所携带的流体的压力通过经由与其接触的传感器元件测量容器或管的形状的变化来测量。 材料，形状和机械支撑协调地确保发生小的非弹性应变，压力测量可重复。 这些实施例与一次性容器和管的使用兼容。