公开(公告)号：US5926357A

公开(公告)日：1999-07-20

申请号：US876274

申请日：1997-06-16

申请人： William H. Elias ,  Timothy A. Fayram

发明人： William H. Elias ,  Timothy A. Fayram

IPC分类号： H01G9/00 ,  H01G9/008 ,  H01G9/10 ,  H01G4/35

CPC分类号： H01G9/008 ,  H01G9/00 ,  H01G9/10 ,  Y10T29/417

摘要： An aluminum electrolytic capacitor with an aluminum housing defining a chamber, and having a feed-through aperture providing communication with the chamber from outside of the housing. A number of aluminum anode layers are positioned within the chamber, and a feed-through member formed of a first conductive material occupies the feed-through aperture. The feed-through member has an inner end extending into the chamber, an outer end extending externally from the housing, and an insulative sleeve encompassing an intermediate portion of the feed-through member and directly contacting the housing at the feed-through aperture to prevent electrical contact between the feed-through member and the housing. A connection element formed of a second different conductive material is attached to the inner end of feed-through member and spaced apart from the housing. A compressible insulative gasket may be positioned between the housing and the connection element to provide insulation and a fluid seal.

摘要翻译： 一种铝电解电容器，其具有限定腔室的铝壳体，并且具有馈通孔，所述馈通孔与所述壳体的外部连通。 多个铝阳极层被定位在腔室内，并且由第一导电材料形成的馈通构件占据馈通孔。 馈通构件具有延伸到室中的内端，从壳体向外延伸的外端，以及包围馈通构件的中间部分并且在馈通孔处直接接触壳体的绝缘套筒，以防止 馈通构件和壳体之间的电接触。 由第二不同的导电材料形成的连接元件附接到馈通件的内端并与壳体隔开。 可压缩绝缘垫圈可以定位在壳体和连接元件之间，以提供绝缘和流体密封。

公开(公告)号：US20120108987A1

公开(公告)日：2012-05-03

申请号：US13342864

申请日：2012-01-03

申请人： Timothy A. Fayram ,  Eric S. Fain ,  Paul A. Levine ,  Anders Björling

发明人： Timothy A. Fayram ,  Eric S. Fain ,  Paul A. Levine ,  Anders Björling

IPC分类号： A61B5/0215

CPC分类号： A61B5/0215 ,  A61B5/02108 ,  A61B5/02116 ,  A61B5/02125 ,  A61B5/0285 ,  A61B5/0295 ,  A61B5/0452 ,  A61B5/6846 ,  A61B2562/0219 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/36585

摘要： Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure.

摘要翻译： 本文提供了可植入系统及其使用方法，用于长期监测动脉血压。 使用植入电极和植入的传感器获得指示患者心脏的电活动的第一信号和指示患者心脏的机械活动的第二信号。 通过测量第一信号的各个特征相对于第二信号的特征之间的时间，可以确定指示收缩压和舒张压的值。 在具体实施例中，这些特征用于确定峰值脉冲到达时间（PPAT），其用于确定指示收缩压的值。 此外，可以使用在第二信号的最大峰值处的峰 - 峰幅度和指示收缩压的值来确定指示舒张压的值。

公开(公告)号：US20090062667A1

公开(公告)日：2009-03-05

申请号：US11848586

申请日：2007-08-31

申请人： Timothy A. Fayram ,  Eric S. Fain ,  Paul A. Levine

发明人： Timothy A. Fayram ,  Eric S. Fain ,  Paul A. Levine

IPC分类号： A61B5/0215

CPC分类号： A61B5/0215 ,  A61B5/02108 ,  A61B5/02116 ,  A61B5/02125 ,  A61B5/0285 ,  A61B5/0295 ,  A61B5/0452 ,  A61B5/6846 ,  A61B2562/0219 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/36585

摘要： Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure.

摘要翻译： 本文提供了可植入系统及其使用方法，用于长期监测动脉血压。 使用植入电极和植入的传感器获得指示患者心脏的电活动的第一信号和指示患者心脏的机械活动的第二信号。 通过测量第一信号的各个特征相对于第二信号的特征之间的时间，可以确定指示收缩压和舒张压的值。 在具体实施例中，这些特征用于确定峰值脉冲到达时间（PPAT），其用于确定指示收缩压的值。 此外，可以使用在第二信号的最大峰值处的峰 - 峰幅度和指示收缩压的值来确定指示舒张压的值。

公开(公告)号：US07181276B1

公开(公告)日：2007-02-20

申请号：US10901403

申请日：2004-07-27

申请人： Rose Province ,  Timothy A. Fayram

发明人： Rose Province ,  Timothy A. Fayram

IPC分类号： A61N1/38

CPC分类号： A61N1/3956 ,  A61N1/3962 ,  A61N1/3987

摘要： An exemplary method includes detecting ventricular fibrillation, delivering a low voltage cardiac stimulus, determining whether the low voltage cardiac stimulus terminated the ventricular fibrillation, and delivering a higher voltage cardiac stimulus if the low voltage cardiac stimulus did not terminate the ventricular fibrillation. In one example, the delivering the low voltage cardiac stimulus occurs within approximately 10 event intervals from the detected onset of ventricular fibrillation; otherwise, delivery of an appropriate higher voltage cardiac stimulus occurs. Other exemplary methods, devices, systems, etc., are also disclosed.

摘要翻译： 示例性方法包括检测心室颤动，递送低电压心脏刺激，确定低电压心脏刺激是否终止心室颤动，以及如果低电压心脏刺激未终止心室颤动则递送较高电压的心脏刺激。 在一个示例中，递送低电压心脏刺激发生在从检测到的心室颤动起始的大约10个事件间隔内; 否则，发生适当的较高电压心脏刺激的传递。 还公开了其它示例性方法，装置，系统等。

公开(公告)号：US07130183B1

公开(公告)日：2006-10-31

申请号：US11346664

申请日：2006-02-03

申请人： Timothy A. Fayram

发明人： Timothy A. Fayram

IPC分类号： H01G2/10 ,  A61N1/18

CPC分类号： H01G9/008 ,  A61N1/3975 ,  A61N1/3981

摘要： An implantable cardioverter-defibrillator has a housing containing cardioverter-defibrillator circuitry and a capacitor assembly. The capacitor assembly includes at least two flat capacitors each having opposed major surfaces. Each capacitor has an anode contact at one major surface, and a cathode contact at the opposite major surface. The anode contact of one of the capacitors contacts the cathode contact of the other. Each capacitor contact may be a thin metal plate covering the entire surface of the capacitor, with each plate connected to corresponding interleaved cathode or anode flat sheets between the plates. A non-conductive perimeter may enclose the sheets and connect the plates to each other.

公开(公告)号：US5792199A

公开(公告)日：1998-08-11

申请号：US900083

申请日：1997-07-24

申请人： Timothy A. Fayram ,  Bruce Kirkpatrick

发明人： Timothy A. Fayram ,  Bruce Kirkpatrick

IPC分类号： A61N1/365

CPC分类号： A61N1/36542

摘要： An implantable cardiac pacemaker having a housing containing pacing circuitry, a signal generator, and an electromagnetic transducer. The transducer has an electrical input line connected to the signal generator, and an electrical output line connected to the pacing circuitry. Consequently, a forcing motion on the transducer sends an electrical signal to the pacing circuitry, and operation of the signal generator causes the transducer to vibrate. The pacemaker may also include a disablement switch connected to the signal generator, with the signal generator operating in response to activation of the switch to cause the transducer to generate an audible warning tone while the pacemaker is disabled.

摘要翻译： 一种可植入心脏起搏器，其具有包含起搏电路的壳体，信号发生器和电磁换能器。 换能器具有连接到信号发生器的电输入线和连接到起搏电路的电输出线。 因此，换能器上的强制运动将电信号发送到起搏电路，并且信号发生器的操作导致换能器振动。 起搏器还可以包括连接到信号发生器的禁用开关，信号发生器响应于开关的激活而操作，以使得在起搏器被禁用时，换能器产生可听见的警告音。

公开(公告)号：US07725186B1

公开(公告)日：2010-05-25

申请号：US11565348

申请日：2006-11-30

申请人： Timothy A. Fayram

发明人： Timothy A. Fayram

IPC分类号： A61N1/37 ,  A61B5/0205

CPC分类号： A61B5/1118 ,  A61B5/1123 ,  A61B5/145 ,  A61B2560/0209 ,  A61B2562/0219 ,  A61N1/3627 ,  A61N1/36585

摘要： Energy efficient methods and systems for using multi-dimensional activity sensors with implantable cardiac devices are provided. In certain embodiments the output of a passive activity sensor (used for rate responsive pacing) is used to trigger temporary use of a relatively high power multi-dimensional activity sensor. In other embodiments, the output of a relatively low power oxygen saturation sensor is used to trigger temporary use of a relatively high power multi-dimensional activity sensor. This description is not intended to be a complete description of, or limit the scope of, the invention.

摘要翻译： 提供了使用具有可植入心脏装置的多维活动传感器的节能方法和系统。 在某些实施例中，被动活动传感器（用于速率响应起搏）的输出用于触发临时使用相对高功率的多维活动传感器。 在其他实施例中，相对较低功率的氧饱和度传感器的输出用于触发临时使用较高功率的多维活动传感器。 本说明书不是对本发明的完整描述或限制本发明的范围。

公开(公告)号：US07653434B1

公开(公告)日：2010-01-26

申请号：US10913942

申请日：2004-08-05

申请人： Robert G. Turcott ,  Michael K. Fang ,  Timothy A. Fayram

发明人： Robert G. Turcott ,  Michael K. Fang ,  Timothy A. Fayram

IPC分类号： A61N1/39

CPC分类号： A61N1/375 ,  A61B5/0031 ,  A61N1/025 ,  A61N1/36514 ,  A61N1/3702 ,  A61N1/3962

摘要： Embodiments of the present invention relate to implantable sensors for obtaining hemodynamic data and/or physiologic data. More specifically, embodiments of the present invention enable additional sensing hardware to be added into implantable devices more quickly and less expensively. Additionally, embodiments of the present invention enable such adding of additional sensing hardware with little or no effect on the conventional functions of the implantable device to which the sensor hardware is being added.

摘要翻译： 本发明的实施例涉及用于获得血液动力学数据和/或生理数据的可植入传感器。 更具体地，本发明的实施例使得能够更快速且更低成本地将附加感测硬件添加到可植入设备中。 此外，本发明的实施例使得能够对附加传感器硬件的可植入装置的常规功能几乎没有或没有影响的附加感测硬件的添加。

公开(公告)号：US5983472A

公开(公告)日：1999-11-16

申请号：US969074

申请日：1997-11-12

申请人： Timothy A. Fayram ,  Benjamin D. Pless ,  Scott McCall ,  Craig Mar

发明人： Timothy A. Fayram ,  Benjamin D. Pless ,  Scott McCall ,  Craig Mar

IPC分类号： A61N1/39 ,  H01G7/00 ,  H01G4/38

CPC分类号： A61N1/3956 ,  H01G9/008 ,  H01G9/08 ,  Y10T29/417 ,  Y10T29/43 ,  Y10T29/435 ,  Y10T29/49789

摘要： A method of manufacturing a capacitor for use in an implantable cardiac defibrillator by forming a set of conductive sheets with the same profile having a sacrificial portion. An alignment figure is formed in each sheet, and the sheets are stacked and aligned by registering the alignment figures with each other. The sacrificial portions are removed from each of the sheets, which are secured together and positioned in a capacitor housing. Each sheet may include two major portions joined by the sacrificial portion, so that each major portion may become part of a separate capacitor stack after the sacrificial portion is removed, doubling manufacturing throughput.

摘要翻译： 一种用于制造用于可植入心脏除颤器的电容器的方法，通过形成具有相同轮廓的一组导电片材具有牺牲部分。 在每个片材中形成对准图，并且通过将对准图彼此对准来堆叠和对准片材。 牺牲部分从固定在一起并定位在电容器壳体中的每个片材中移除。 每个片材可以包括由牺牲部分连接的两个主要部分，使得在牺牲部分被去除之后，每个主要部分可以成为单独的电容器堆叠的一部分，使制造生产量翻倍。

公开(公告)号：US5522851A

公开(公告)日：1996-06-04

申请号：US350853

申请日：1994-12-06

申请人： Timothy A. Fayram

发明人： Timothy A. Fayram

IPC分类号： A61N1/39

CPC分类号： A61N1/3956

摘要： A capacitor having a housing defining a chamber, and having at least two internal alignment elements in the chamber. A plurality of capacitor layers, each having alignment holes formed therein to precisely fit the housing's alignment elements, is positioned within the chamber, with the alignment holes mating with the alignment elements. The housing may be electrically conductive and used to connect some capacitor elements, in which case the alignment elements include non conductive spacers that contact the alignment holes of the sheets. The housing may also include external index elements for precisely positioning the housing in registration with fixtures used for manufacturing processes requiring precise alignment.

摘要翻译： 一种电容器，其具有限定腔室的壳体，并且在腔室中具有至少两个内部对准元件。 每个具有形成在其中以精确配合壳体对准元件的对准孔的电容器层定位在腔室内，其中对准孔与对准元件配合。 壳体可以是导电的并且用于连接一些电容器元件，在这种情况下，对准元件包括接触片材对准孔的非导电间隔物。 壳体还可以包括外部指标元件，用于将壳体精确地定位成与用于需要精确对准的制造过程的夹具对准。