公开(公告)号：US08701512B2

公开(公告)日：2014-04-22

申请号：US12965420

申请日：2010-12-10

申请人： Naohisa Sakamoto ,  Noriyuki Kishii ,  Kazumine Ito

发明人： Naohisa Sakamoto ,  Noriyuki Kishii ,  Kazumine Ito

IPC分类号： B01L3/00 ,  G01N15/14 ,  G01N33/58

CPC分类号： B01L3/502761 ,  B01L3/502753 ,  B01L2200/0668 ,  B01L2300/0681 ,  B01L2300/0822 ,  B01L2300/0877 ,  B01L2400/0487 ,  G01N15/1463 ,  G01N33/582

摘要： Disclosed herein is a cell for testing microbeads, used for testing microbeads each formed in a cylindrical shape having an upper surface and a lower surface opposite to and substantially parallel to each other and a side surface continuous with the upper and lower surfaces, at least one of the upper surface and the lower surface being provided with an identification pattern, the cell including: a support substrate; and a cover disposed opposite to the support substrate, wherein a space between the support substrate and the cover forms a containing space in which to dispose the microbeads, and the distance between the support substrate and the cover is greater than the thickness of the microbeads and smaller than twice the thickness of the microbeads.

摘要翻译： 本文公开了一种用于测试微珠的细胞，用于测试各自形成为具有上表面和与彼此相对并基本平行的上表面和下表面以及与上表面和下表面连续的侧表面的圆柱形形状的微珠，至少一个 的上表面和下表面设置有识别图案，所述单元包括：支撑基板; 以及与所述支撑基板相对设置的盖，其中所述支撑基板和所述盖之间的空间形成容纳微珠的容纳空间，并且所述支撑基板和所述盖之间的距离大于所述微珠的厚度， 小于微珠厚度的两倍。

公开(公告)号：US08546068B2

公开(公告)日：2013-10-01

申请号：US13120967

申请日：2009-09-04

申请人： Mari Ichimura ,  Kenzo Machida ,  Noriyuki Kishii ,  Masanobu Tanaka

发明人： Mari Ichimura ,  Kenzo Machida ,  Noriyuki Kishii ,  Masanobu Tanaka

IPC分类号： G03F7/26

CPC分类号： G01N33/54313 ,  B01J2219/00432 ,  B01J2219/005 ,  B01J2219/00502 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00677 ,  B01J2219/00722

摘要： In one example embodiment, a method fabricates microbeads, which can supply a bead set containing a various types of microbeads and having distinct populations of the respective types of microbeads. In one example embodiment, the method includes forming a hydrophilic layer made of a hydrophilic organic material on a substrate. In one example embodiment, the method includes laminating on the hydrophilic layer a thin film capable of being peeled off in the form of microbeads. In one example embodiment, the method includes forming the thin film in a given configuration by photolithography. In one example embodiment, the method includes solid-phasing a given substance on the post-formed thin films. In one example embodiment, the method includes peeling off the post-formed thin films, which have been solid-phased with the substance, from the substrate along with at least a part of the hydrophilic layer to obtain microbeads.

摘要翻译： 在一个示例性实施例中，一种制造微珠的方法，其可以提供包含各种类型的微珠并且具有各种类型的微珠的不同种群的珠粒组。 在一个示例性实施例中，该方法包括在基底上形成由亲水性有机材料制成的亲水层。 在一个示例性实施例中，该方法包括在亲水层上层叠能够以微珠形式剥离的薄膜。 在一个示例性实施例中，该方法包括通过光刻法以给定的配置形成薄膜。 在一个示例性实施例中，该方法包括将定影物质固定在后成形薄膜上。 在一个示例性实施例中，该方法包括将已经与物质固相化的后成形薄膜与至少一部分亲水层一起从衬底剥离以获得微珠。

公开(公告)号：US20090274908A1

公开(公告)日：2009-11-05

申请号：US12432108

申请日：2009-04-29

申请人： Kenzo Machida ,  Noriyuki Kishii ,  Mari Ichimura ,  Masanobu Tanaka

发明人： Kenzo Machida ,  Noriyuki Kishii ,  Mari Ichimura ,  Masanobu Tanaka

IPC分类号： B32B1/00 ,  G03F7/20

CPC分类号： B01J19/0046 ,  B01J2219/00432 ,  B01J2219/00459 ,  B01J2219/00466 ,  B01J2219/005 ,  B01J2219/00502 ,  B01J2219/00542 ,  B01J2219/00547 ,  B01J2219/00556 ,  B01J2219/00558 ,  B01J2219/0056 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00617 ,  B01J2219/00619 ,  B01J2219/00626 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00722 ,  Y10T428/2991

摘要： The present application provides a process for the preparation of microbeads, including the steps of: patterning a thin film, which has been formed on a substrate, into microbead regions of at least one predetermined shape by photolithography; immobilizing a predetermined substance on the thus-patterned microbead regions; and stripping off, from the substrate, the thus-patterned microbead regions with the substance immobilized thereon.

摘要翻译： 本申请提供了一种制备微珠的方法，包括以下步骤：通过光刻将形成在基材上的薄膜图案化成至少一个预定形状的微珠区域; 将预定物质固定在如此构图的微珠区域上; 并从基材上剥离固定有物质的如此图案化的微珠区域。

公开(公告)号：US20060276335A1

公开(公告)日：2006-12-07

申请号：US10565918

申请日：2004-08-16

申请人： Hisanori Tsuboi ,  Kenichi Kurihara ,  Noriyuki Kishii

发明人： Hisanori Tsuboi ,  Kenichi Kurihara ,  Noriyuki Kishii

IPC分类号： B05D5/12 ,  B05D3/00 ,  B41M5/24

CPC分类号： B41M5/34 ,  B41M5/305 ,  C09B11/24 ,  C09B23/0016 ,  C09B23/0033 ,  C09B23/0066 ,  C09B23/086 ,  C09B23/105 ,  C09B49/128 ,  C09B57/008

摘要： A reversible multicolor thermal recording medium capable of recording and erasing repeatedly high-contrast clear images free of color fogging without causing color deterioration and a method for recording on the recording medium. The reversible multicolor recording medium includes recording layers numbered from the first to the nth, which are formed on a supporting substrate separately and independently in sequential order, the recording layers each containing a reversible thermal color developing composition differing from one another in the hue of the developed color and further containing a light-heat converting composition which generates heat upon absorption of near infrared rays with a wavelength in different ranges, and the recording layers having respectively the absorption peak wavelengths λ max 1, λ max 2, . . . , λ max n, in the near infrared region such that 1500 nm>λ max 1>λ max 2> . . . >λ max n>750 nm.

摘要翻译： 一种可反复多色热记录介质，能够记录和擦除重复的高对比度清晰图像而不产生着色，而不引起颜色劣化，以及记录在记录介质上的方法。 可逆式多色记录介质包括从第一至第n编号的记录层，它们以顺序分开独立地形成在支撑基板上，记录层各自包含彼此不同的可逆热色彩显影组合物 显影的颜色，并且还含有在吸收波长在不同范围内的近红外线时产生热的光热转换组合物，并且记录层分别具有吸收峰值波长λmax 1，λmax 2。 。 。 ，λmax n，在近红外区域，使得1500nm>λmax 1>λmax 2>。 。 。 >λmax n> 750nm。

公开(公告)号：US06989356B2

公开(公告)日：2006-01-24

申请号：US10408904

申请日：2003-04-08

申请人： Ken Kobayashi ,  Takahiro Kamei ,  Noriyuki Kishii ,  Kenichi Kurihara ,  Yutaka Iwamoto ,  Hisanori Tsuboi

发明人： Ken Kobayashi ,  Takahiro Kamei ,  Noriyuki Kishii ,  Kenichi Kurihara ,  Yutaka Iwamoto ,  Hisanori Tsuboi

IPC分类号： C10M105/50 ,  C07C69/62 ,  G11B5/725

CPC分类号： C07C69/63 ,  Y10S428/90

摘要： To provide a lubricant for recording medium, which is advantageous not only in that it maintains excellent lubricity under various conditions for use and excellent lubricating effect over a long time, but also in that it can impart excellent transport properties and excellent abrasion resistance as well as excellent durability. For example, when C18H37—CH(CH2COOC10H6OH)COORf (wherein Rf represents a saturated or unsaturated partially-fluorinated-alkyl group) is used as a lubricant for magnetic recording medium, there can be obtained a magnetic recording medium having excellent transport properties and excellent abrasion resistance as well as excellent durability.

摘要翻译： 为了提供用于记录介质的润滑剂，这不仅有利于其在各种使用条件下保持优异的润滑性并且在长时间内保持优异的润滑效果，而且还可以赋予优异的输送性能和优异的耐磨性，以及 优良的耐用性。 例如，当C 18 H 30 -CH（CH 2 CH 2 CH 3）H 6时， （其中R f表示饱和或不饱和的部分氟化的烷基）用作磁记录介质的润滑剂，可以获得具有优异的输送性能和优异的耐磨性以及优异的耐磁性的磁记录介质 耐久性

公开(公告)号：US5153099A

公开(公告)日：1992-10-06

申请号：US500239

申请日：1990-03-26

申请人： Noriyuki Kishii ,  Shinichiro Tamura ,  Nobutoshi Asai ,  Koichi Kawasumi ,  Junetsu Seto

发明人： Noriyuki Kishii ,  Shinichiro Tamura ,  Nobutoshi Asai ,  Koichi Kawasumi ,  Junetsu Seto

IPC分类号： C07D487/22 ,  G11B7/248

CPC分类号： C07D487/22 ,  G11B7/248 ,  Y10S430/146

摘要： A wavelength multiplexed optical recording material is disclosed wherein a photosensitive material including substituted porphine, such as tetra(pentafluorophenyl) porphine or tetra(4-methoxyphenyl) porphine, is uniformly dispersed into an optically transparent dispersion medium. When such wavelength multiplexed optical recording material is cooled to a temperature of liquid helium and irradiated with a laser beam, a large number of holes of narrow width are formed in an inhomogenous absorption band under the phenomenon of photochemical hole burning. As compared to unsubstituted porphine, the above porphine derivatives give an improved recording sensitivity and narrow hole width.

摘要翻译： 公开了一种波长复合光学记录材料，其中包括取代的卟吩如四（五氟苯基）卟吩或四（4-甲氧基苯基）卟吩的光敏材料均匀地分散在光学透明的分散介质中。 当这种波长多路复用光学记录材料被冷却到液氦温度并用激光照射时，在光化学孔燃烧现象下，大量的宽度窄的孔形成为不均匀的吸收带。 与未取代的卟吩相比，上述卟吩衍生物具有改善的记录灵敏度和窄孔宽度。

公开(公告)号：US20110183272A1

公开(公告)日：2011-07-28

申请号：US13120967

申请日：2009-09-04

申请人： Mari Ichimura ,  Kenzo Machida ,  Noriyuki Kishii ,  Masannobu Tanaka

发明人： Mari Ichimura ,  Kenzo Machida ,  Noriyuki Kishii ,  Masannobu Tanaka

IPC分类号： G03F7/20

CPC分类号： G01N33/54313 ,  B01J2219/00432 ,  B01J2219/005 ,  B01J2219/00502 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00677 ,  B01J2219/00722

摘要： In one example embodiment, a method fabricates microbeads, which can supply a bead set containing a various types of microbeads and having distinct populations of the respective types of microbeads. In one example embodiment, the method includes forming a hydrophilic layer made of a hydrophilic organic material on a substrate. In one example embodiment, the method includes laminating on the hydrophilic layer a thin film capable of being peeled off in the form of microbeads. In one example embodiment, the method includes forming the thin film in a given configuration by photolithography. In one example embodiment, the method includes solid-phasing a given substance on the post-formed thin films. In one example embodiment, the method includes peeling off the post-formed thin films, which have been solid-phased with the substance, from the substrate along with at least a part of the hydrophilic layer to obtain microbeads.

摘要翻译： 在一个示例性实施例中，一种制造微珠的方法，其可以提供包含各种类型的微珠并且具有各种类型的微珠的不同种群的珠粒组。 在一个示例性实施例中，该方法包括在基底上形成由亲水性有机材料制成的亲水层。 在一个示例性实施例中，该方法包括在亲水层上层叠能够以微珠形式剥离的薄膜。 在一个示例性实施例中，该方法包括通过光刻法以给定的配置形成薄膜。 在一个示例性实施例中，该方法包括将定影物质固定在后成形薄膜上。 在一个示例性实施例中，该方法包括将已经与物质固相化的后成形薄膜与至少一部分亲水层一起从衬底剥离以获得微珠。

公开(公告)号：US20090279787A1

公开(公告)日：2009-11-12

申请号：US12432121

申请日：2009-04-29

申请人： Noriyuki Kishii ,  Mari Ichimura ,  Kenzo Machida

发明人： Noriyuki Kishii ,  Mari Ichimura ,  Kenzo Machida

IPC分类号： G06K9/46 ,  B32B1/00

CPC分类号： G06K19/06037 ,  G06T7/74 ,  G06T2207/30072 ,  G06T2207/30208 ,  Y10T428/2991

摘要： A microbead automatic recognition method includes the steps of: acquiring an image of a circular surface of a cylindrical microbead having a recognition pattern created on the circular surface and a plurality of reference points also created on the circular surface; and acquiring information on the rear/front and/or orientation of the cylindrical microbead from the acquired image on the basis of the positions of the reference points.

摘要翻译： 微珠自动识别方法包括以下步骤：获取具有在圆形表面上产生的识别图案的圆柱形微珠的圆形表面的图像和在圆形表面上也产生的多个参考点; 并且根据参考点的位置从获取的图像获取关于圆柱形微珠的后/前和/或取向的信息。

公开(公告)号：US20090275743A1

公开(公告)日：2009-11-05

申请号：US12432078

申请日：2009-04-29

申请人： Michihiro Ohnishi ,  Noriyuki Kishii ,  Takuya Kishimoto ,  Naoyuki Sasaki ,  Hidetoshi Watanabe

发明人： Michihiro Ohnishi ,  Noriyuki Kishii ,  Takuya Kishimoto ,  Naoyuki Sasaki ,  Hidetoshi Watanabe

IPC分类号： C07H1/00 ,  B01J19/00 ,  B05D3/00

CPC分类号： C12N15/1006

摘要： The present invention provides a method for producing a carrier for nucleic acid separation, the method including a step of: immobilizing capturing chains onto a porous carrier having cation-exchangeable groups thereon by ion exchange bonding, the capturing chains having a base sequence complementary to target nucleic acid chains and being modified with functional groups having positive charges.

摘要翻译： 本发明提供了一种核酸分离用载体的制造方法，该方法包括以下步骤：通过离子交换键将捕获链固定在其上具有阳离子交换基团的多孔载体上，捕获链具有与靶相互补充的碱基序列 核酸链，并用具有正电荷的官能团修饰。