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    Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof
    31.
    发明授权
    Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof 有权
    包含至少一种恶唑啉以抑制朗格汉斯细胞迁移的组合物及其用途

    公开(公告)号：US08653117B2

    公开(公告)日：2014-02-18

    申请号：US12352973

    申请日：2009-01-13

    Applicant: Philippe Msika ,  Nathalie Piccardi ,  Antoine Piccirilli

    Inventor： Philippe Msika ,  Nathalie Piccardi ,  Antoine Piccirilli

    IPC: A61K31/421 ,  A61K38/02 ,  A61P35/00

    CPC classification number: A61K31/42 ,  A61K8/49 ,  A61K2800/51 ,  A61K2800/70 ,  A61K2800/75 ,  A61K2800/782 ,  A61Q19/00 ,  A61Q19/005 ,  A61Q19/08 ,  Y10S514/861

    Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.

    Abstract translation: 本发明涉及至少含有恶唑啉的组合物，任选地与至少一种化合物如金属蛋白酶抑制剂，PKC抑制剂，抗炎剂，舒缓剂，免疫抑制剂，离子螯合剂，链烷醇酰胺， 恶唑烷酮和氨基甲酸衍生物。 本发明还涉及使用这种组合物作为药物，特别是用于预防或治疗过敏和/或炎性和/或刺激性起源或由危险信号引起的皮肤病理学。 本发明还涉及一种用于美容治疗敏感的，刺激的，不耐受的，过敏倾向的，老化的皮肤和/或表现皮肤屏障障碍的皮肤或/或表现出非病理性免疫不平衡的皮肤和/或粘膜的方法，其包括在皮肤和/ 或粘膜。

    EXTRACT OF THE ABOVE-GROUND PORTIONS OF GYNANDROPSIS GYNANDRA OR CLEOME GYNANDRA, AND COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS INCLUDING SAME
    33.
    发明申请
    EXTRACT OF THE ABOVE-GROUND PORTIONS OF GYNANDROPSIS GYNANDRA OR CLEOME GYNANDRA, AND COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS INCLUDING SAME 有权
    提取GYNANDROPSIS GYNANDRA或CLEOME GYNANDRA的上述部分，以及包括其中的化妆品，皮肤或药物组合物

    公开(公告)号：US20130171082A1

    公开(公告)日：2013-07-04

    申请号：US13824187

    申请日：2011-12-22

    Applicant: Philippe Msika ,  Alex Saunois ,  Caroline Baudouin ,  Sophie Leclere-Bienfait ,  Sebastien Debrock

    Inventor： Philippe Msika ,  Alex Saunois ,  Caroline Baudouin ,  Sophie Leclere-Bienfait ,  Sebastien Debrock

    IPC: A61K36/185 ,  A61K8/97 ,  A61K45/00

    CPC classification number: A61K36/185 ,  A61K8/602 ,  A61K8/97 ,  A61K45/00 ,  A61K2800/805 ,  A61Q19/06 ,  A61Q19/08

    Abstract: The invention relates to a composition, such as a cosmetic, dermatological, or pharmaceutical composition, including an extract of the above-ground portions of Gynandropsis gynandra, advantageously the leaves and, optionally, a suitable carrier. The invention also relates to such a composition or such an extract to be used in the prevention or treatment of disorders or diseases of the skin, mucous membranes, or nails and hair, to be used in the prevention or treatment of vascular disorders and/or problems linked to hyperseborrhea, or further to be used as an anti-ageing, healing, moisturising, slimming and/or anti-cellulite, anti-allergy and pro-pigmenting product. Finally, the invention relates to a cosmetic care method for the skin, nails and hair, or mucous membranes, with a view to improving the condition or appearance thereof, consisting of administering such a composition or such an extract.

    Abstract translation: 本发明涉及一种组合物，例如化妆品，皮肤病学或药物组合物，包括Gynandropsis gynandra的地上部分的提取物，有利地是叶和任选的合适的载体。 本发明还涉及这种用于预防或治疗皮肤，粘膜或指甲和毛发的疾病或疾病的组合物或提取物，其用于预防或治疗血管疾病和/或 与高脂血症相关的问题，或进一步用作抗衰老，愈合，保湿，减肥和/或抗脂肪团，抗过敏和促色素产品。 最后，本发明涉及一种用于皮肤，指甲和头发或粘膜的美容护理方法，以改善其状况或外观，包括施用这种组合物或这种提取物。

    Use of a rice protein hydrolysate as pigmenting active principle
    36.
    发明授权
    Use of a rice protein hydrolysate as pigmenting active principle 有权
    使用大米蛋白水解产物作为着色剂的活性成分

    公开(公告)号：US08231916B2

    公开(公告)日：2012-07-31

    申请号：US12299009

    申请日：2007-07-18

    Applicant: Philippe Msika ,  Dalale Naaïmi

    Inventor： Philippe Msika ,  Dalale Naaïmi

    IPC: A61K36/89 ,  A61K36/00 ,  A61K38/00 ,  A61Q17/04 ,  A01N65/00 ,  A61P17/00

    CPC classification number: A61K8/645 ,  A61Q5/10 ,  A61Q17/04 ,  A61Q19/04

    Abstract: The present invention concerns the use of a rice protein hydrolysate in order to pigment the skin and skin appendages. Thus, it is possible to intensify the normal pigmentation of the skin without sunlight. Preferred areas of applications are repigmentation of white patches of the skin, repigmentation of white patches of the skin as a consequence of pityriasis or due to the use of dermocorticoids; acceleration and intensification of the tanning process, stimulation of the constitutive photoprotection and improvement of the phototype, prevention of skin photocarcinogenesis. Advantageously, the rice protein hydrolysate comprises peptides of which at least 50% have a molecular mass in the range of between 300 and 3,500 Da.

    Abstract translation: 本发明涉及使用大米蛋白水解产物以使皮肤和皮肤附着物着色。 因此，可以在没有阳光的情况下加强皮肤的正常色素沉积。 优选的应用领域是由于糠疹或由于使用皮肤激素而导致的皮肤白色斑块的染色，皮肤白色斑块的分解， 加速和加强鞣制过程，刺激组成型光保护和改善光型，防止皮肤光致癌。 有利地，大米蛋白水解产物包含其中至少50％的分子量在300和3,500Da之间的肽。

    COSMETIC COMPOSITION FOR THE TREATMENT OF ACNE COMPRISING A PEPTIDE EXTRACT OF SCHIZANDRA
    37.
    发明申请
    COSMETIC COMPOSITION FOR THE TREATMENT OF ACNE COMPRISING A PEPTIDE EXTRACT OF SCHIZANDRA 有权
    化疗组合物治疗胃酸肽提取物

    公开(公告)号：US20120121725A1

    公开(公告)日：2012-05-17

    申请号：US13387518

    申请日：2010-07-27

    Applicant: Sebastien Garnier ,  Dalale Naaimi ,  Caroline Baudouin

    Inventor： Sebastien Garnier ,  Dalale Naaimi ,  Caroline Baudouin

    IPC: A61K38/02 ,  A61K8/27 ,  A61K33/30 ,  A61Q19/00 ,  A61K8/19 ,  A61K36/28 ,  A61K8/97 ,  A61P17/10 ,  A61K8/64 ,  A61K33/34

    CPC classification number: A61K8/602 ,  A61K8/645 ,  A61K8/97 ,  A61K36/79 ,  A61Q19/00

    Abstract: The present invention relates to a cosmetic, nutraceutical or dermatological composition for treating or preventing acne, comprising a peptide and oside extract of Schizandra fruit and a suitable excipient. Preferably, the extract is obtained from Schizandra sphenanthera. The composition may also comprise at least one anti-acne agent selected from a sebum-regulating agent, an antibacterial and/or antifungal agent, a keratolytic agent and/or a keratoregulating agent, an astringent, an anti-inflammatory and/or anti-irritant, an antioxidant and/or a free-radical scavenger, a cicatrizing agent, an anti-ageing agent and a moisturizing agent. The invention also relates to a method for cosmetic treatment of acne, characterized in that a cosmetic composition according to the invention is applied to the affected areas of the skin, or in that the affected individual takes a nutraceutical composition according to the invention orally.

    Abstract translation: 本发明涉及用于治疗或预防痤疮的化妆品，保健品或皮肤病学组合物，其包含五味子果实的肽和盎司提取物以及合适的赋形剂。 优选地，提取物是从五味子（Schisandra sphenanthera）获得的。 组合物还可以包含至少一种选自皮脂调节剂，抗菌剂和/或抗真菌剂，角质分解剂和/或角质调节剂，收敛剂，抗炎剂和/或抗真菌剂的抗痤疮剂。 刺激物，抗氧化剂和/或自由基清除剂，c zing剂，抗老化剂和保湿剂。 本发明还涉及一种美容治疗痤疮的方法，其特征在于将根据本发明的化妆品组合物应用于皮肤的受影响区域，或者受影响的个体口服本发明的营养组合物。

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