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公开(公告)号:US20240042104A1
公开(公告)日:2024-02-08
申请号:US18368332
申请日:2023-09-14
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Eldad TZAHOR , Elad BASSAT
CPC classification number: A61L27/54 , C12N5/0657 , A61K38/1709 , A61P9/10 , C07K14/4725 , A61L2300/252 , C12N2501/998
Abstract: An Agrin peptide which induces proliferation of cardiomyocytes for treating a heart disease is provided.
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32.
公开(公告)号:US11856379B2
公开(公告)日:2023-12-26
申请号:US17434208
申请日:2019-11-27
Inventor: Changbao Zhu
CPC classification number: H04R3/12 , G10L15/25 , G10L15/30 , H04S7/302 , H04R2420/03
Abstract: Disclosed are a method, an apparatus and an electronic device for controlling audio playback of multiple loudspeakers, wherein the method comprises: determining the location information of each speaker and voice signals issued by each speaker; determining the area where each speaker is located according to the location information of each speaker; determining voice instruction corresponding to each voice signal; and controlling the multiple loudspeakers to play the audio indicated by the corresponding voice instruction respectively for the area where the speaker of each voice instruction is located. According to the method and apparatus and/or the electronic device in an embodiment of the present disclosure, different audios can be played for different areas in a preset space.
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33.
公开(公告)号:US20230409886A1
公开(公告)日:2023-12-21
申请号:US18247408
申请日:2022-02-10
Inventor: Zhuoran ZHAO , Kai YU , Chang HUANG , Zhenjiang WANG , Jianjun LI , Delin LI , Yinan ZHANG
IPC: G06N3/0464
CPC classification number: G06N3/0464
Abstract: The present disclosure provides a method and apparatus for deconvolving feature data using convolution hardware. The method includes: reading a feature map and deconvolution kernel into on-chip memory, and padding zeroes to the feature map; determining convolution kernels based on the deconvolution kernel; removing a row and/or column of each convolution kernel whose elements all are invalid weights, to obtain an optimized convolution kernel, and removing a corresponding row and/or column in the zero-padded feature map to obtain an corresponding optimized feature map; convolving each optimized convolution kernel with corresponding optimized feature map using the multiply-add array, to obtain convolutional outputs; and interleaving and synthesizing the convolutional outputs to obtain an interleaving synthetic output including at least a deconvolutional output corresponding to the feature map and deconvolution kernel. The method reduces hardware complexity, chip area and power consumption, and many invalid operations, improving operating efficiency of convolution hardware.
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公开(公告)号:US11847535B2
公开(公告)日:2023-12-19
申请号:US18300584
申请日:2023-04-14
Inventor: Gil Semo , Ziv Aqua , Oded Melamed , Dan Charash , Serge Rosenblum , Barak Dayan
IPC: G06N10/40
CPC classification number: G06N10/40
Abstract: A quantum computing system includes a first silicon nitride resonator couplable to a first alkali atom, a second silicon resonator couplable to a second alkali atom, and a plurality of lasers for trapping, cooling, and manipulating the first alkali atom and the second alkali atom. Detectors detect a presence of the trapped first alkali atom and the trapped second alkali atom, and a processor is configured to receive at least one input signal from at least one of the detectors, the input signal indicating a presence of the trapped first alkali atom and the trapped second alkali atom, and, based on the received input, control at least some of the plurality of lasers to manipulate at least one of the trapped first alkali atom and the trapped second alkali atom to thereby generate photonic qubits using the trapped first alkali atom or generate entanglement between photonic qubits transmitted to the trapped second alkali atom.
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公开(公告)号:US11846636B2
公开(公告)日:2023-12-19
申请号:US16751831
申请日:2020-01-24
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Irun R. Cohen , Eytan Domany , Noam Shental , Ittai Fattal
IPC: G01N33/53 , G01N33/564 , C12Q1/6883 , A61K31/711
CPC classification number: G01N33/564 , A61K31/711 , C12Q1/6883 , C12Q2600/158 , C12Q2600/16 , G01N33/5308 , G01N2800/104
Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.
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36.
公开(公告)号:US11844827B2
公开(公告)日:2023-12-19
申请号:US17531897
申请日:2021-11-22
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yair Reisner , Noga Or-Geva , Eran Ophir , Yaki Eidelstein , Rotem Gidron Budovsky
IPC: A61K39/00 , A61K35/17 , C12N5/078 , C12N5/0783 , A61P31/00 , A61P35/04 , A61K39/395 , C07K16/28 , A61K35/12
CPC classification number: A61K39/001 , A61K35/17 , A61K39/39566 , A61P31/00 , A61P35/04 , C07K16/2896 , C12N5/0636 , C12N5/0637 , C12N5/0648 , A61K2035/122 , A61K2039/5158 , C12N2501/2307 , C12N2501/2315 , C12N2501/2321 , Y02A50/30
Abstract: An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes following transplantation, the cell being transduced to express a cell surface receptor comprising a T cell receptor signaling module is disclosed. Methods of generating same and using same are also disclosed.
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公开(公告)号:US20230383254A1
公开(公告)日:2023-11-30
申请号:US18232437
申请日:2023-08-10
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yair REISNER , Noga OR-GEVA , Rotem GIDRON BUDOVSKY , Esther BACHAR-LUSTIG , Assaf LASK , Sivan KAGAN
IPC: C12N5/0783 , A61K35/17 , A61K39/00 , C12N5/00
CPC classification number: C12N5/0637 , A61K35/17 , A61K39/001 , C12N5/0087 , A61K2035/122
Abstract: A method of generating an isolated population of non graft versus host disease (GvHD) inducing cells comprising a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and/or endowed with anti-disease activity, and capable of homing to the lymph nodes following transplantation is disclosed. The method comprising: (a) providing a population of at least 70% memory T cells; (b) contacting the population of memory T cells with an antigen or antigens so as to allow enrichment of antigen reactive cells; and (c) culturing the cells resulting from step (b) in the presence of cytokines so as to allow proliferation of cells comprising the Tcm phenotype. Cells generated by the method, pharmaceutical compositions and methods of treatment are also disclosed.
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38.
公开(公告)号:US20230366885A1
公开(公告)日:2023-11-16
申请号:US18350066
申请日:2023-07-11
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: David MARGULIES , Leila Motiei , Naama Lahav , Pragati Prasad
IPC: G01N33/58 , G01N33/574
CPC classification number: G01N33/582 , G01N33/574
Abstract: The disclosure presented herein provides DNA constructs, recombinant cells comprising thereof, system comprising thereof, bacterial probes, and/or a recombinant cell decorated with various labels and/or synthetic agents, wherein said labels and/or synthetic agents can be reversibly modified or removed from the cells. Also disclosed herein are methods for decorating and/or modifying cells, preferably bacteria cells, and methods for using thereof.
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公开(公告)号:US11786640B2
公开(公告)日:2023-10-17
申请号:US16746878
申请日:2020-01-19
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Eldad Tzahor , Elad Bassat
CPC classification number: A61L27/54 , A61K38/1709 , A61P9/10 , C07K14/4725 , C12N5/0657 , A61L2300/252 , C12N2501/998
Abstract: An Agrin peptide which induces proliferation of cardiomyocytes for treating a heart disease is provided.
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公开(公告)号:US20230321235A1
公开(公告)日:2023-10-12
申请号:US18020441
申请日:2021-08-11
Applicant: Yeda Research and Development Co. Ltd. , Ichilov Tech Ltd.
Inventor: Yair REISNER , Anat GLOBERSON LEVIN , Esther BACHAR-LUSTIG , Assaf LASK , Bar NATHANSOHN-LEVI , Tova WAKS , Galit HORN , Zelig ESHHAR
IPC: A61P35/00 , C12N5/0783 , A61K39/00
CPC classification number: A61K39/4611 , A61K39/4631 , A61P35/00 , C12N5/0636 , A61K2239/22 , C12N2510/00
Abstract: A method of generating a population of genetically modified veto cells is disclosed. The method comprising: (a) providing a population of cells comprising T cells, the T cells comprising at least 40% memory CD8+ T cells; (b) culturing the population of cells comprising T cells with an antigen or antigens under conditions which allow enrichment of tolerance-inducing antigen-specific cells having a central memory T-lymphocyte (Tcm) phenotype, the cells being depleted of graft versus host (GVH) reactivity; and (c) transducing the cells with a polynucleotide encoding a heterologous cell surface receptor comprising a T cell receptor signaling module, thereby generating the population of genetically modified veto cells.
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