公开(公告)号：US20080027520A1

公开(公告)日：2008-01-31

申请号：US11750873

申请日：2007-05-18

申请人： George Choi ,  Kasey Li

发明人： George Choi ,  Kasey Li

IPC分类号： A61N5/067 ,  A61N7/02

CPC分类号： A61B18/24 ,  A61B17/1688 ,  A61B2018/00029 ,  A61B2018/2005 ,  A61N5/0603 ,  A61N7/022 ,  A61N2005/0607

摘要： Laser treatment of tissue, particularly the tissues in or around the nasal and oral cavities, are described herein. One method for reducing the size of the tissue being treated is to apply laser energy to the underlying tissue. One instrument may be used to deliver laser energy and to optionally provide an infusion or injection of a fluid directly into the tissue as well as optionally provide for ultrasound energy application as well. One or more optical fibers which may extend through needles inserted into the tissue may be utilized to deliver the laser energy.

摘要翻译： 本文描述了组织，特别是鼻腔和口腔内或周围的组织的激光治疗。 一种减少正在治疗的组织的尺寸的方法是将激光能量施加到下面的组织。 一种仪器可用于提供激光能量，并且可选地提供将液体直接注入或注射到组织中，并且还可选地提供超声能量应用。 可以通过插入到组织中的针延伸的一根或多根光纤来传送激光能量。

公开(公告)号：US07306588B2

公开(公告)日：2007-12-11

申请号：US10963213

申请日：2004-10-12

申请人： Marvin P. Loeb ,  L. Dean Crawford ,  James W. Pergl ,  Randy P. Graham

发明人： Marvin P. Loeb ,  L. Dean Crawford ,  James W. Pergl ,  Randy P. Graham

IPC分类号： A61B18/20

CPC分类号： A61B18/24 ,  A61B2018/00023 ,  A61B2018/2005 ,  A61B2018/2277

摘要： The invention relates to a catheter device including an optical fiber whose distal end is disposed within a hollow tube with a sharp or needle shaped distal end, which can penetrate tissue. The distal end of the optical fiber and the hollow tube are configured so as to emit, by refraction (total internal reflection) or reflection from a metal surface, laser energy at an angle of about 80° to about 90° relative to the longitudinal axis of the optical fiber and hollow tube. The hollow tube is mounted to a housing and may be surrounded by a sheath.

摘要翻译： 本发明涉及一种导管装置，其包括光纤，其远端设置在具有尖锐或针状远端的中空管中，该远端可穿透组织。 光纤的远端和中空管被配置为通过折射（全内反射）或来自金属表面的反射而发射相对于纵向轴线大约80°至大约90°的角度的激光能量 的光纤和中空管。 中空管安装到壳体上并且可以被护套包围。

公开(公告)号：US20070179485A1

公开(公告)日：2007-08-02

申请号：US11641155

申请日：2006-12-19

申请人： Glenn Yeik ,  L. Crawford

发明人： Glenn Yeik ,  L. Crawford

IPC分类号： A61B18/18

CPC分类号： A61B18/24 ,  A61B2018/2005 ,  A61B2018/2272

摘要： Improved laser energy delivery devices, providing greater transmission efficiency, longevity of use and safety are described. In one embodiment, a device for delivering laser energy includes a conventional optical fiber within a metal or plastic cannula provided with a laser energy emission window. A reflective material is disposed in a space between the distal end portion of a metal or plastic sheath and the optical fiber, as well as about any extension or endpiece of the distal end of the sheath. The reflective material reflects aberrant emissions of laser energy from the optical fiber as it erodes, and laser energy backscattered from the target tissue away from the distal end of the sheath back into the optical fiber or out of the distal end of the sheath, thereby preventing damage due to overheating. Other embodiments include devices that transmit laser energy more safely, efficiently and durably laterally from the axis of the optical fiber.

摘要翻译： 描述了改进的激光能量传递装置，提供更大的传输效率，使用寿命和安全性。 在一个实施例中，用于传送激光能量的装置包括设置有激光能量发射窗口的金属或塑料插管内的常规光纤。 反射材料设置在金属或塑料护套的远端部分与光纤之间的空间中，以及围绕护套远端的任何延伸部分或末端部分。 反射材料反射来自光纤的激光能量的异常发射，并且激光能量从目标组织远离护套的远端向后退回到光纤中或者脱离护套的远端，从而防止 由于过热造成的损坏 其他实施例包括从光纤的轴线更安全，有效和持久地横向地传输激光能量的装置。

公开(公告)号：US20070088218A1

公开(公告)日：2007-04-19

申请号：US11543505

申请日：2006-10-05

申请人： John McIntyre ,  Elbert Tzeng

发明人： John McIntyre ,  Elbert Tzeng

IPC分类号： A61B8/14

CPC分类号： A61B17/3478 ,  A61B18/1477 ,  A61B18/24 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2018/00166 ,  A61B2018/00392 ,  A61B2018/1425 ,  A61B2018/2005

摘要： The present invention contemplates a surgical device for both ablating a channel in a patient's tissue and also delivering a therapeutic agent. The device includes an elongated multi-lumen tube, an elongated tissue ablating assembly, and a therapeutic agent delivery assembly. The therapeutic agent is capable of being delivered into the channel and/or to the surrounding tissue. The device may further include a second multi-lumen tube also capable of delivering therapeutic agents. Although suitable for many operations, the device is particularly well suited for transmyocardial revascularization operations. The present invention also contemplates a procedure for using such a surgical device to ablate a channel in a patient's tissue and also deliver a therapeutic agent.

摘要翻译： 本发明考虑了用于消融患者组织中的通道并且还递送治疗剂的手术装置。 该装置包括细长多腔管，细长组织消融组件和治疗剂递送组件。 治疗剂能够被输送到通道和/或周围组织中。 该装置还可以包括还能够递送治疗剂的第二多腔管。 尽管适用于许多操作，该装置特别适用于经心肌血运重建操作。 本发明还考虑了使用这种外科装置消融患者组织中的通道并递送治疗剂的程序。

公开(公告)号：US07167741B2

公开(公告)日：2007-01-23

申请号：US10014846

申请日：2001-12-14

申请人： Mark G. Torchia ,  Richard Tyc ,  John S. Pacak

发明人： Mark G. Torchia ,  Richard Tyc ,  John S. Pacak

IPC分类号： A61B5/00

CPC分类号： A61B18/24 ,  A61B5/055 ,  A61B18/20 ,  A61B90/36 ,  A61B2018/00023 ,  A61B2018/00196 ,  A61B2018/00636 ,  A61B2018/1861 ,  A61B2018/2005 ,  A61B2018/2277 ,  A61B2090/374

摘要： This surgical device uses a laser beam to coagulate tissue. The elongate device carries the beam through an optical fiber that has a chamfered end for deflecting the beam out of a distal end of the device at an angle. Tissue coagulation is monitored using a magnetic resonance imaging system that provides periodic tissue temperature data. A small fluid supply duct provides cooling fluid that expands to a gas near the distal end of the device, thereby cooling the tip.

摘要翻译： 该手术装置使用激光束凝固组织。 细长装置通过具有倒角端的光纤携带光束，用于以一定角度将光束偏离装置的远端。 使用提供周期性组织温度数据的磁共振成像系统监测组织凝血。 小的流体供应管道提供冷却流体，其膨胀到靠近设备的远端的气体，从而冷却尖端。

公开(公告)号：US20060241727A1

公开(公告)日：2006-10-26

申请号：US11381950

申请日：2006-05-05

申请人： Kambiz Dowlatshahi

发明人： Kambiz Dowlatshahi

IPC分类号： A61N5/06

CPC分类号： A61B6/0414 ,  A61B6/502 ,  A61B10/02 ,  A61B18/20 ,  A61B50/20 ,  A61B2018/2005 ,  A61B2090/376 ,  A61N5/0601

摘要： Apparatus and method for performing interstitial laser therapy and adjunctive therapy on a patient are revealed. The apparatus employs a combination of a mammography unit, an interstitial laser treatment device attached to the mammography unit and a treatment platform positioned relative to the mammography unit to enable the interstitial laser therapy to be performed. The use of the treatment platform with the mammography unit enables the interstitial laser therapy to be performed and, if necessary, adjunctive therapy to be performed in the same treatment room without transferring the patient to a new platform.

摘要翻译： 揭示了对患者进行间质激光治疗和辅助治疗的装置和方法。 该装置使用乳房X线照相术单元，连接到乳房X线照相术单元的间质激光治疗装置和相对于乳房X线照相术装置定位的治疗平台的组合，以实现间质激光治疗。 使用具有乳房X线照相术单元的治疗平台能够执行间质激光治疗，并且如果需要，在相同治疗室中进行辅助治疗而不将患者转移到新平台。

公开(公告)号：US20060095095A1

公开(公告)日：2006-05-04

申请号：US11210276

申请日：2005-08-23

申请人： Densen Cao

发明人： Densen Cao

IPC分类号： A61N5/06 ,  A61B18/18

CPC分类号： A61B18/22 ,  A61B2018/2005 ,  A61B2018/208 ,  A61N5/06 ,  A61N5/0601

摘要： A method for killing cancer cells, including placing fiber needles into a human body adjacent cancerous cells, and exposing the cancerous cells to laser light emitted through the fiber needles so that the laser light tends to cause death of the cancer cells.

摘要翻译： 一种用于杀死癌细胞的方法，包括将纤维针放置在与癌细胞相邻的人体内，并将癌细胞暴露于通过纤维针发射的激光，使得激光趋于导致癌细胞死亡。

公开(公告)号：US06865412B2

公开(公告)日：2005-03-08

申请号：US10754827

申请日：2004-01-09

申请人： Kambiz Dowlatshahi

发明人： Kambiz Dowlatshahi

IPC分类号： A61B5/01 ,  A61B5/00 ,  A61B5/05 ,  A61B5/06 ,  A61B6/00 ,  A61B6/04 ,  A61B8/06 ,  A61B17/00 ,  A61B18/00 ,  A61B18/20 ,  A61B18/24 ,  A61B19/00 ,  A61N5/06

CPC分类号： A61B5/06 ,  A61B5/01 ,  A61B5/064 ,  A61B6/0414 ,  A61B6/502 ,  A61B8/06 ,  A61B18/20 ,  A61B2017/00084 ,  A61B2018/00011 ,  A61B2018/2005 ,  A61B2018/206 ,  A61B2090/063 ,  A61N5/0601

摘要： An apparatus and method for determining a volume of tumor mass destroyed. The present invention includes a temperature probe and a laser probe having a temperature sensor. The laser probe and temperature probe are inserted to measure a temperature of the tumor mass and a temperature of tissue mass surrounding the tumor mass. By determining the volume of tumor mass destroyed, a graphical representation of the volume of tumor mass destroyed is provided whereby real-time visual monitoring of the destruction of the tumor mass is achieved.

公开(公告)号：US20030191449A1

公开(公告)日：2003-10-09

申请号：US10405394

申请日：2003-04-02

申请人： Kensey Nash Corporation

发明人： John E. Nash ,  Douglas G. Evans ,  David M. Hoganson

IPC分类号： A61M025/00

CPC分类号： A61B17/32037 ,  A61B17/320758 ,  A61B17/3478 ,  A61B18/14 ,  A61B18/1492 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/22038 ,  A61B2018/00208 ,  A61B2018/00291 ,  A61B2018/00392 ,  A61B2018/00839 ,  A61B2018/1861 ,  A61B2018/2005

摘要： A system for accessing targeted tissue within the living being and introduction of particles at select locations into the myocardium and other select tissues. The system includes an instrument and a plurality of flowable particles to be delivered by the instrument via an externally applied force. The particles to the tissue may include one or more of pharmaceuticals, biologically active agents, radiopaque materials, etc.

摘要翻译： 用于获取生物体内目标组织的系统，以及将选定位置处的颗粒引入心肌和其它选择组织。 该系统包括一个仪器和多个可流动的颗粒，由仪器通过外部施加的力传递。 组织中的颗粒可以包括药物，生物活性剂，不透射线材料等中的一种或多种。

公开(公告)号：US20020193781A1

公开(公告)日：2002-12-19

申请号：US09881190

申请日：2001-06-14

发明人： Marvin P. Loeb

IPC分类号： A61B018/04 ,  A61B018/14 ,  A61B018/20

CPC分类号： A61B18/22 ,  A61B18/1402 ,  A61B18/1477 ,  A61B18/1492 ,  A61B2017/00274 ,  A61B2017/00867 ,  A61B2018/00547 ,  A61B2018/00982 ,  A61B2018/1425 ,  A61B2018/2005 ,  A61B2090/3937 ,  A61N7/02

摘要： A device is provided for interstitial delivery of thermal energy and/or a biologically compatible bulking material into tissues in a confined space. The device include means for delivering laser, radio-frequency, electrical, microwave, ultrasound or other thermal energy, as well as a port and channel for concomitant or subsequent injection of a bulking agent. The method of use of the device in the treatment of female stress incontinence (FSI), gastro-esophageal reflex disease (GERD), benign prostate hyperplasia (BPH) and other conditions is described.

摘要翻译： 提供了用于将热能和/或生物相容的填充材料间隙传送到密闭空间中的组织的装置。 该装置包括用于传送激光，射频，电，微波，超声波或其他热能的装置，以及用于伴随或随后注射填充剂的端口和通道。 描述了该装置在治疗女性压力性尿失禁（FSI），胃食管反射疾病（GERD），良性前列腺增生症（BPH）等情况下的使用方法。