公开(公告)号：US07244397B2

公开(公告)日：2007-07-17

申请号：US10470943

申请日：2002-01-10

申请人： Hans Jürgen Bigus

发明人： Hans Jürgen Bigus

IPC分类号： B01L3/02 ,  G05D9/00 ,  G01N1/14

CPC分类号： B01L3/0203 ,  B01L3/0227 ,  Y10T436/2575

摘要： The invention relates to a digital burette having a manual drive for suctioning and applying an adjustable dose volume, a gear unit connected downstream and a digital display device controlled thereby for setting the dose volume. The control comprises an incremental encoder which is functionally connected to the gear unit, at least one sensor for detecting the signals produced by the incremental encoder and a processor connected to the sensor and the display device for calculating the dose volume corresponding to the number of signals. The incremental encoder is, in particular, a sector disc with two groups of sectors of different magnetic field strength disposed alternately in the peripheral direction of the sector disc. A sensor detects the number of turns of the sector disc. To save energy, the power supply of the burette is ensured by a solar cell and two spaced sensors are provided for detecting the number of turns of the sector disc to reduce the clock frequency of the processor for a same measuring accuracy. The invention also relates to a method for displaying the dose volume of such a digital burette.

摘要翻译： 本发明涉及一种具有用于抽吸和施加可调节剂量的手动驱动器的数字滴定管，连接在下游的齿轮单元和由此控制的数字显示装置，用于设定剂量体积。 控制器包括功能上连接到减速器的增量式编码器，用于检测由增量式编码器产生的信号的至少一个传感器和连接到传感器的处理器和显示装置，用于计算与信号数量对应的剂量量 。 特别地，增量式编码器是具有不同磁场强度的两组扇区的扇形盘在扇形盘的圆周方向交替设置。 传感器检测扇区盘的匝数。 为了节省能源，通过太阳能电池确保滴定管的电源，并且提供两个间隔的传感器用于检测扇形盘的匝数，以便以相同的测量精度降低处理器的时钟频率。 本发明还涉及一种用于显示这种数字滴定管的剂量体积的方法。

公开(公告)号：US20060039824A1

公开(公告)日：2006-02-23

申请号：US11257152

申请日：2005-10-25

申请人： Takehiko Onuma

发明人： Takehiko Onuma

IPC分类号： B01L3/00 ,  G01N35/00

CPC分类号： B01L3/021 ,  B01L3/0227 ,  B01L2200/143 ,  G01N35/1002 ,  G01N35/1016 ,  G01N2035/00673 ,  Y10T137/0324 ,  Y10T137/0329 ,  Y10T137/0335 ,  Y10T137/034 ,  Y10T137/0346 ,  Y10T137/0352 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/2575

摘要： An automatic analyzer analyzes a measurement item by making a sample and reagent react with each other and measuring the reaction result. This apparatus allows parameters associated with reagent dispensing executed by a reagent dispensing mechanism to be set as a dispensing condition for each measurement item or each type of reagent, and controls the reagent dispensing mechanism on the basis of the dispensing condition.

公开(公告)号：US20040223888A1

公开(公告)日：2004-11-11

申请号：US10874021

申请日：2004-06-21

发明人： Felix H. Yiu

IPC分类号： B01L003/02

CPC分类号： G01N35/1074 ,  B01L3/022 ,  B01L3/0227 ,  B01L3/0279 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2300/0838

摘要： A pipettor uses no pistons in order to provide highly automated, precise and accurate pipetting operations. Additionally, a self-aligning pipette tip enables better engagement of such pipette tips by the pipettor. The pipette tips may be automatically engaged and locked into place by the pipettor and may be automatically disengaged to enable highly-automated pipetting processes for industrial and laboratory purposes. Open proximal ends of the pipette tips are engaged by a pipette block, which then forms a temporary seal with the individual pipette tips. Displacement of the pipette block with respect to the pipette tips increased or decreases the effective volume of the pipette tip allowing it to aspirate or expel fluids in a precise, accurate, and predictable way. Additionally, seals may be seated in grooves engraved in either the pipette tip or the pipette block to provide a sliding seal between the pipette block and pipette tip.

公开(公告)号：US06778917B1

公开(公告)日：2004-08-17

申请号：US09431457

申请日：1999-11-01

申请人： Dirk Jansen

发明人： Dirk Jansen

IPC分类号： G01R2106

CPC分类号： B01L3/0227 ,  B01L2300/027

摘要： A method for operating an electronic metering system with an electronic hand metering device which includes an electrical drive, at least one displacement device such as a piston drivable by the drive, a program-controlled electronic control, at least one non-volatile write-read memory, an electrical voltage source and a data interface connected to the electronic control, with a computer and a data transfer device. The data transfer device includes a data interface for connecting the data interface of the metering device to the computer such that parameters specific to the apparatus type, apparatus, user parameters, routines for carrying out operating procedures, the program and at least one programming part may be written into and read from the write-read memory and read from the hand metering device can be remote controlled.

摘要翻译： 一种用于操作具有电子手动计量装置的电子计量系统的方法，该电子手动计量装置包括电驱动器，至少一个位移装置，例如由驱动器驱动的活塞，程序控制的电子控制，至少一个非易失性写入读取 存储器，电压源和连接到电子控制的数据接口，与计算机和数据传输装置。 数据传送装置包括用于将计量装置的数据接口连接到计算机的数据接口，使得特定于装置类型，装置，用户参数，用于执行操作程序的程序，程序和至少一个编程部分的参数可以 写入读取存储器并从读取记录仪上读取可以进行远程控制。

公开(公告)号：US06739478B2

公开(公告)日：2004-05-25

申请号：US10180710

申请日：2002-06-25

申请人： David T. Bach ,  Muniswamappa Anjanappa ,  Gayathri S. Ragavan ,  Tao Song

发明人： David T. Bach ,  Muniswamappa Anjanappa ,  Gayathri S. Ragavan ,  Tao Song

IPC分类号： G01F1106

CPC分类号： B01L3/0206 ,  B01F5/12 ,  B01L3/0227 ,  B01L2400/0622 ,  F04B7/04 ,  F04B13/00

摘要： A precision fluid dispensing system containing at least one two-piece pump and a precision closed loop controller drive system to address the small volume precision dispensing requirements of bioscience applications. A multiple diameter pump can be combined with a pump having multiple inlet and outlet ports to allow for precision multiple outlet dispenses in a single pump that finds use with microtiter plate pipetting and other precision dispensing. Inlet ports can be located on the smaller diameter of the cylinder with outlet ports on the larger diameter of the cylinder. A micro-controller with closed loop feedback provides exact linear positioning and motion of the pump piston as well as optional control of a nozzle to provide exact micro-dispensing of fluids.

摘要翻译： 精密流体分配系统，包含至少一个两件式泵和精密闭环控制器驱动系统，以解决生物科学应用的小体积精密分配要求。 多直径泵可以与具有多个入口和出口的泵组合，以允许精确的多个出口分配在单个泵中，其可用于微量滴定板移液和其它精确分配。 入口端口可以位于气缸的较小直径上，出口端口在气缸的较大直径上。 具有闭环反馈的微控制器提供了泵活塞的精确线性定位和运动，以及喷嘴的可选控制，以提供精确的微分配流体。

公开(公告)号：US20030190263A1

公开(公告)日：2003-10-09

申请号：US10119100

申请日：2002-04-08

发明人： Felix H. Yiu

IPC分类号： B01L003/02

CPC分类号： B01L3/0227 ,  B01L3/0279 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2300/0838 ,  G01N35/1074

摘要： A pipettor uses no pistons in order to provide highly automated, precise and accurate pipetting operations. Additionally, a self-aligning pipette tip enables better engagement of such pipette tips by the pipettor. The pipette tips may be automatically engaged and locked into place by the pipettor and may be automatically disengaged to enable highly-automated pipetting processes for industrial and laboratory purposes. Open proximal ends of the pipette tips are engaged by a pipette block, which then forms a temporary seal with the individual pipette tips. Displacement of the pipette block with respect to the pipette tips increased or decreases the effective volume of the pipette tip allowing it to aspirate or expel fluids in a precise, accurate, and predictable way.

摘要翻译： 移液器不使用活塞，以提供高度自动化，精确和精确的移液操作。 此外，自动对准移液器吸头可以通过移液器更好地接合这种吸头。 移液管吸头可以通过移液器自动接合并锁定就位，并且可以自动脱开以实现用于工业和实验室目的的高度自动化的移液过程。 打开移液管尖端的近端由移液管块接合，然后移液管块与单独的移液管尖端形成临时密封。 移液管块相对于移液管尖端的位移增加或减少移液管尖端的有效体积，使其能够以精确，准确和可预测的方式吸入或排出流体。

公开(公告)号：US20030099578A1

公开(公告)日：2003-05-29

申请号：US10271867

申请日：2002-10-16

发明人： Richard Cote ,  Robert Henry Zier

IPC分类号： B01L003/02

CPC分类号： B01L3/0224 ,  B01L3/0227 ,  B01L3/0279 ,  G10L15/26

摘要： A hand-held pipettor comprising a piston received in one end of a cylinder, a pipettor tip removably secured to an opposite end of said cylinder, means for reciprocating said piston through a selected stroke to aspirate fluid into and to expel the thus aspirated fluid from said pipettor tip, mutually spaced stop members operatively associated with said manually driven means for defining the range of said stroke and motor driven means for varying the spacing between said stop members to thereby vary the volume of fluid being aspirated into and expelled from said pipettor tip.

摘要翻译： 一种手持移液器，包括容纳在气缸的一端的活塞，可移除地固定到所述气缸的相对端的移液器吸头，用于使所述活塞通过选定行程往复运动的装置，以将流体吸入并排出由此吸出的流体 所述移液器末端，与所述手动驱动装置可操作地相关联的相互间隔开的止动构件，用于限定所述冲程和马达驱动装置的范围，用于改变所述止动构件之间的间隔，从而改变被吸入和从所述移液器吸头排出的流体体积 。

公开(公告)号：US20020022802A1

公开(公告)日：2002-02-21

申请号：US09880602

申请日：2001-06-13

发明人： Frank B. Simpson

IPC分类号： A61M005/178

CPC分类号： B01L3/0227 ,  G01N1/38

摘要： A wrap spring clutch syringe ram pushes one or more syringes precisely, rapidly, reproducibly, and reliably, with virtually instantaneous starting and stopping, and with constant motion at a defined velocity during the intervening push. The wrap spring clutch syringe ram includes an electric motor, a computer, a flywheel, a wrap spring clutch, a precision lead screw, a slide platform, and syringe reservoirs, a mixing chamber, and a reaction incubation tube. The electric motor drives a flywheel and the wrap spring clutch couples the precision lead screw to the flywheel when a computer enables a solenoid of the wrap spring clutch. The precision lead screw drives a precision slide which causes syringes to supply a portion of solution into the mixing chamber and the incubation tube. The wrap spring clutch syringe ram is designed to enable the quantitative study of solution phase chemical and biochemical reactions, particularly those reactions that occur on the subsecond time scale.

摘要翻译： 包裹弹簧离合器注射器柱塞可以精确，快速，可再现和可靠地推动一个或多个注射器，几乎瞬时启动和停止，并且在中间推动期间以限定的速度恒定运动。 卷簧弹簧离合器注射器柱塞包括电动机，计算机，飞轮，卷簧弹簧离合器，精密丝杠，滑动平台和注射器容器，混合室和反应孵育管。 电动机驱动飞轮并且当计算机启用卷簧弹簧离合器的螺线管时，卷簧弹簧离合器将精密丝杠耦合到飞轮。 精密导螺杆驱动精密滑动件，使得注射器将一部分溶液供应到混合室和孵育管中。 封闭弹簧离合器注射器柱塞设计用于定量研究溶液相化学和生化反应，特别是在次级时间尺度上发生的那些反应。

公开(公告)号：US06299841B1

公开(公告)日：2001-10-09

申请号：US09263131

申请日：1999-03-05

申请人： Kenneth Rainin ,  Christopher Kelly ,  James S. Petrek

发明人： Kenneth Rainin ,  Christopher Kelly ,  James S. Petrek

IPC分类号： B01L302

CPC分类号： B01L3/0227 ,  B01L3/0286 ,  B01L2200/087 ,  B01L2300/027 ,  Y10T436/2575

摘要： A bilaterally symmetrical lightweight hand holdable battery powered microprocessor controlled electronic pipette including an axially elongated hollow housing having a vertically extending longitudinal axis. An upper portion of the housing includes a forward compartment containing a forwardly facing alpha-numeric display, a plurality of columns of forwardly facing control keys and plurality of forwardly facing trigger switches arranged in a vertically spaced pattern such that a user in gripping a lower handle portion of the housing in either his or her right or left hand can easily reach with his thumb the control keys, trigger switches as well as a push button of a pipette tip ejector.

摘要翻译： 一种双向对称的轻量级可手持电池供电的微处理器控制电子移液器，其包括具有垂直延伸的纵向轴线的轴向细长的中空壳体。 壳体的上部包括一个前部隔间，它包含一个向前面对的字母数字显示器，多个向前面对的控制键列和多个向前的触发开关，以垂直间隔的图案布置，使得使用者抓住一个下手柄 外壳的右侧或左侧的部分可以用拇指轻松到达控制键，触发开关以及移液器顶端喷射器的按钮。

公开(公告)号：US5567122A

公开(公告)日：1996-10-22

申请号：US322214

申请日：1994-10-13

申请人： Harvey Schulte

发明人： Harvey Schulte

IPC分类号： B01L3/02 ,  F04B9/02 ,  F04B23/06 ,  F04B49/00 ,  A61M5/20

CPC分类号： F04B23/06 ,  B01L3/0227 ,  F04B9/02 ,  Y10S128/01

摘要： A cylinder pump having a controllable piston/drive detachment is disclosed that can engage or disengage a piston rod using a solenoid. Most any type of drive can be used. The cylinder pump could have one or more cylinders. Each cylinder and piston rod has quick connect and disconnect mountings. The cylinder pump could be a syringe pump or drive.

摘要翻译： 公开了一种具有可控制的活塞/驱动器分离的气缸泵，其可以使用螺线管接合或分离活塞杆。 大多数任何类型的驱动器都可以使用。 气缸泵可以具有一个或多个气缸。 每个气缸和活塞杆均具有快速连接和拆卸安装。 气缸泵可以是注射泵或驱动器。