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公开(公告)号:US2771396A
公开(公告)日:1956-11-20
申请号:US55198755
申请日:1955-12-09
申请人: PFIZER & CO C
IPC分类号: C07C227/16 , C12P13/04 , C12P13/08
CPC分类号: C12P13/04 , C07C227/16 , C12P13/08 , Y10S435/823 , Y10S435/849
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公开(公告)号:US1908225A
公开(公告)日:1933-05-09
申请号:US51377331
申请日:1931-02-05
申请人: PFIZER CHARLES & CO
发明人: CURRIE JAMES N , ALEXANDER FINLAY
CPC分类号: C12N1/34 , C12P7/58 , Y10S435/823
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公开(公告)号:US20120129272A1
公开(公告)日:2012-05-24
申请号:US13360081
申请日:2012-01-27
IPC分类号: G01N33/543
CPC分类号: G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要: In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements.
摘要翻译: 一方面,诊断测试系统包括壳体,读取器和数据分析器。 壳体包括用于接收测试条的端口。 读取器从暴露于光学检查的检测区域的区域的局部区域获得可分离的光强度测量值,其中每个局部区域的特征在于至少一个小于第一维度的表面尺寸。 数据分析器识别从至少一个测试区域获得的光强度测量结果中的一个,并从所识别的光强测量中计算至少一个参数。 在另一方面,读取器从检测区域的暴露表面区域的多个对应区域中的每一个获得相应的一组光强度测量值,并且数据分析器从至少一个光强度测量集合中计算至少一个参数 。
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公开(公告)号:US20090180925A1
公开(公告)日:2009-07-16
申请号:US12409861
申请日:2009-03-24
申请人: Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人: Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号: G01N31/22
CPC分类号: G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
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公开(公告)号:US20090106865A1
公开(公告)日:2009-04-23
申请号:US12313592
申请日:2008-11-21
IPC分类号: A01H5/10
CPC分类号: A01H17/00 , Y10S435/822 , Y10S435/823
摘要: Non-leguminous crops, e.g. wheat, maize and rice, do not form nodules and are dependant for their nutrition on fixed nitrogen from the soil, or from chemical/nitrogenous fertilizers. The present invention provides non-leguminous plants and leguminous plants, including legumes that fail to nodulate with Rhizobia, with bacteria that enable them to fix nitrogen endophytically. Therefore, the plants contain nitrogen fixing bacteria the bacteria being located intracellularly in living plant cells.
摘要翻译: 非豆科作物,例如 小麦,玉米和大米不会形成结节,并且依赖于在土壤或化学/氮肥肥料固定氮素上的营养。 本发明提供非豆科植物和豆科植物,包括不能根瘤菌结瘤的豆类,以及能够内生固氮的细菌。 因此,植物含有固氮细菌,细菌位于活细胞内细胞。
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公开(公告)号:US07521260B2
公开(公告)日:2009-04-21
申请号:US11280640
申请日:2005-11-16
申请人: Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人: Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号: G01N33/533
CPC分类号: G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
摘要翻译: 测定试片包括流路,样品接收区,标签,包括感兴趣区域的检测区和至少一个位置标记。 所述至少一个位置标记相对于所述感兴趣区域对齐,使得所述至少一个位置标记的位置指示所述感兴趣区域的位置。 诊断测试系统包括从测试条的暴露区域获得光强度测量的读取器,以及数据分析器,其执行以下至少一个:(a)基于至少一个(a)识别从测试区域获得的光强度测量中的一个 测量从所述至少一个参考特征获得的,以及(b)基于从所述至少一个参考特征获得的至少一个测量值生成修改所述读取器的至少一个操作参数的控制信号。
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公开(公告)号:US20060240568A1
公开(公告)日:2006-10-26
申请号:US11280640
申请日:2005-11-16
申请人: Patrick Petruno , John Petrilla , Michael Brosnan , Rong Zhou , Daniel Roitman , Bo Curry
发明人: Patrick Petruno , John Petrilla , Michael Brosnan , Rong Zhou , Daniel Roitman , Bo Curry
IPC分类号: G01N33/558
CPC分类号: G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
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公开(公告)号:US20050227371A1
公开(公告)日:2005-10-13
申请号:US11088579
申请日:2005-03-23
申请人: Cem Gokhan
发明人: Cem Gokhan
IPC分类号: G01N33/543 , G01N33/558
CPC分类号: G01N33/558 , G01N33/54386 , G01N2500/10 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/823 , Y10T436/25125
摘要: The invention relates to devices for performing single step assays for the determination of the presence or absence of an analyte in a liquid sample, and methods of determining the presence or absence of such analytes using such devices. Devices disclosed comprise a labeled analyte-binding reagent reversibly-immobilized on a non-porous solid material, which solid material is in physical contact with a dry porous carrier bearing an immobilized analyte-binding reagent. Also provided are quantitative assay devices.
摘要翻译: 本发明涉及用于执行用于确定液体样品中分析物的存在或不存在的单步测定的装置,以及使用这种装置确定这种分析物的存在或不存在的方法。 所公开的装置包括可逆地固定在无孔固体材料上的标记的分析物结合试剂,该固体材料与带有固定的分析物结合试剂的干燥多孔载体物理接触。 还提供定量测定装置。
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39.
公开(公告)号:US06855561B2
公开(公告)日:2005-02-15
申请号:US09950366
申请日:2001-09-10
申请人: Jeremy Jerome , Mark Daquipa , Bruce Jacono , Hans Boehringer
发明人: Jeremy Jerome , Mark Daquipa , Bruce Jacono , Hans Boehringer
IPC分类号: G01N21/86 , G01N33/543 , G01N33/558 , G01N33/53
CPC分类号: G01N21/8483 , B01L3/5023 , G01N33/54386 , G01N33/558 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要: A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.
摘要翻译: 一种用于确定流体样品中分析物的存在或不存在的测试装置和方法,所述测试装置包括在其上具有标记的支撑件和限定轴向流动路径的矩阵。 在操作中,测试装置中的观察区域变得透明,从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常,底层支持上的标记被配置为减号( - )。 在样品中没有分析物的情况下,测试装置呈负值(-1)信号。 然而,在样品中存在分析物的情况下,标记与观察区域上的垂直测试线一致,以将正的结果呈现为使用者可见的加号(+)信号。
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公开(公告)号:US06818434B2
公开(公告)日:2004-11-16
申请号:US10162073
申请日:2002-06-05
申请人: Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
发明人: Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
IPC分类号: C12P1904
CPC分类号: C12R1/02 , C12P19/04 , C12R1/01 , Y10S435/823
摘要: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
摘要翻译: 新型的纤维素生成菌,包括能够生产聚苯乙烯换算重量平均聚合度为1.6×10 4以上的细菌纤维素的纤维素生产菌,能够生产含有少量馏分的细菌纤维素的细菌纤维素, 低聚合度,一种生产宾汉多糖作为副产物,一种产生少量水溶性多糖; 一种生产细菌纤维素的方法,包括培养这些纤维素生产菌; 和由此获得的细菌纤维素。
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