公开(公告)号：US09782742B2

公开(公告)日：2017-10-10

申请号：US15107064

申请日：2015-03-26

申请人： Jiangnan University

发明人： Xueming Xu ,  Na Yang ,  Yamei Jin ,  Nannan Zhang ,  Dandan Li ,  Fengfeng Wu ,  Zhengyu Jin ,  Yisheng Chen ,  Xing Zhou ,  Aiquan Jiao ,  Jie Ren

IPC分类号： C12M1/42 ,  B01J19/08 ,  C12N13/00 ,  B01D11/04 ,  H01F7/06 ,  H01F7/02 ,  H02P31/00 ,  H01F27/28 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P7/58 ,  C12M1/00

CPC分类号： B01J19/087 ,  B01D11/0419 ,  B01J2219/0801 ,  B01J2219/0854 ,  B01J2219/0871 ,  C12M21/18 ,  C12M29/18 ,  C12M35/02 ,  C12M35/06 ,  C12N13/00 ,  C12P7/58 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  H01F7/0205 ,  H01F7/0294 ,  H01F7/064 ,  H01F27/2823 ,  H02P31/00

摘要： An inductive magnetoelectric biochemical reaction system includes a reaction unit which includes a reaction chamber, which includes a reactant container and is disposed in a rotatable perpendicular magnetic field; a primary coil, which is wound around one side of a closed-loop iron core and is connected to a control unit; a secondary coil, which is wound around the other side of the closed-loop iron core and includes an insulating tube which allows a reaction solution acting as a conductor, two ends of the insulating tube being communicated with the reactant container; a rotating magnetic field unit, which is configured to generate the rotatable perpendicular magnetic field; and a control unit, which is at least configured to adjust an excitation voltage and a signal type applied on the primary coil.

公开(公告)号：US20170137788A1

公开(公告)日：2017-05-18

申请号：US15412757

申请日：2017-01-23

申请人： AMANO ENZYME INC.

发明人： Miho NAGAYA ,  Akiko SUGITA ,  Naoki MATSUMOTO ,  Masamichi OKADA

IPC分类号： C12N9/04 ,  A23L15/00 ,  A21D8/04 ,  C12N15/52

CPC分类号： C12N9/0006 ,  A21D8/042 ,  A23J1/008 ,  A23J3/04 ,  A23L1/3208 ,  A23L5/00 ,  A23L15/25 ,  A23L29/06 ,  A23V2002/00 ,  C12N15/52 ,  C12P7/44 ,  C12P7/58 ,  C12P17/04 ,  C12P19/12 ,  C12Y101/03004

摘要： A protein having a novel saccharide oxidase activity capable of being subjected to various uses is provided. The present invention provides a protein having the following physicochemical characteristics: (1) effect: oxidizing a saccharide to produce a saccharic acid; (2) substrate specificity: acting on glucose, maltotriose, maltose, galactose, maltotetraose, lactose, and cellobiose; and, (3) [Km value of glucose]/[Km value of maltose]≦1.

公开(公告)号：US09493796B2

公开(公告)日：2016-11-15

申请号：US15047118

申请日：2016-02-18

申请人： XYLECO, INC.

发明人： Marshall Medoff ,  Thomas Craig Masterman

IPC分类号： C12N11/02 ,  C12P7/10 ,  C07H3/02 ,  C07H3/04 ,  C12N1/20 ,  C12P7/06 ,  C12P5/02 ,  C12P7/04 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/52 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P7/64 ,  C12P19/02 ,  C12N1/38

CPC分类号： C12P7/10 ,  C07H3/02 ,  C07H3/04 ,  C12N1/20 ,  C12N1/38 ,  C12P5/02 ,  C12P7/04 ,  C12P7/06 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/52 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P7/6409 ,  C12P19/02 ,  C12P2201/00 ,  C12P2203/00 ,  Y02E50/16 ,  Y02E50/17 ,  Y02E50/343

摘要： Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to proceed ethanol and/or butanol, e.g., by fermentation.

公开(公告)号：US09260705B2

公开(公告)日：2016-02-16

申请号：US14588231

申请日：2014-12-31

申请人： Codexis, Inc.

发明人： Dipnath Baidyaroy ,  Louis Clark ,  David Elgart ,  Rama Voladri ,  Xiyun Zhang

IPC分类号： C12N9/42 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04 ,  C12P19/14 ,  C12P19/02 ,  C12N15/80 ,  C12P7/14 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P13/14

CPC分类号： C12N9/2437 ,  C12N15/80 ,  C12P7/14 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P13/14 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01091 ,  Y02E50/16

摘要： The present invention relates to cellobiohydrolase variants having improved thermostability in comparison to wild-type CBH2a.

公开(公告)号：US20150291947A1

公开(公告)日：2015-10-15

申请号：US14437760

申请日：2013-10-22

申请人： NOVOZYMES A/S

发明人： Peter WESTH ,  Jeppe KARI ,  Johan OLSEN ,  Kim BORCH ,  Kenneth JENSEN ,  Kristian B. R. M. KROGH

IPC分类号： C12N9/42 ,  C12P19/12 ,  C12P7/02 ,  C12P7/18 ,  C12P7/16 ,  C12P7/10 ,  C12P7/20 ,  C12P7/04 ,  C12P5/02 ,  C12P5/00 ,  C12P13/20 ,  C12P13/14 ,  C12P13/00 ,  C12P13/08 ,  C12P13/06 ,  C12P3/00 ,  C12P7/26 ,  C12P7/28 ,  C12P7/40 ,  C12P7/54 ,  C12P7/44 ,  C12P17/04 ,  C12P7/48 ,  C12P7/58 ,  C12P7/42 ,  C12P7/56 ,  C12P7/52 ,  C12P7/46 ,  C12P19/14

CPC分类号： C12N9/2437 ,  C12P3/00 ,  C12P5/002 ,  C12P5/007 ,  C12P5/02 ,  C12P5/023 ,  C12P5/026 ,  C12P7/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/26 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/44 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P13/005 ,  C12P13/06 ,  C12P13/08 ,  C12P13/14 ,  C12P13/20 ,  C12P17/04 ,  C12P19/12 ,  C12P19/14 ,  C12Y302/01091 ,  C12Y302/01176 ,  Y02E50/16

摘要： The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

摘要翻译： 本发明涉及纤维二糖水解酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US09045789B2

公开(公告)日：2015-06-02

申请号：US13914872

申请日：2013-06-11

申请人： AJINOMOTO CO., INC.

发明人： Yousuke Nishio ,  Youko Yamamoto ,  Kazuteru Yamada ,  Kosuke Yokota

IPC分类号： C12P13/14 ,  C12P7/50 ,  C12N15/52 ,  C12N9/04 ,  C12N9/02 ,  C12N9/16 ,  C12N9/88 ,  C12P7/58 ,  C12P13/00 ,  C12P13/04 ,  C12P13/10 ,  C12P13/24

CPC分类号： C12P13/14 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/16 ,  C12N9/88 ,  C12N15/52 ,  C12P7/50 ,  C12P7/58 ,  C12P13/001 ,  C12P13/04 ,  C12P13/10 ,  C12P13/24 ,  C12Y101/01113 ,  C12Y102/01026 ,  C12Y103/05001 ,  C12Y301/01068 ,  C12Y402/01082

摘要： A target substance can be produced by culturing a bacterium having an ability to produce 2-ketoglutaric acid or a derivative thereof, and an ability to produce xylonic acid from xylose, which is imparted with xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities are enhanced, in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium.

摘要翻译： 目标物质可以通过培养具有生产2-酮戊二酸或其衍生物的能力的细菌和从赋予木糖酸脱水酶活性的木糖中产生木糖酸的能力，2-酮-3-脱氧木糖酸脱水酶 活性和2-酮戊二醛半醛脱氢酶活性，或其中这些活性增强的培养基，在含有木糖作为碳源的培养基中培养和累积目标物质，并从培养基中收集目标物质。

公开(公告)号：US08975048B2

公开(公告)日：2015-03-10

申请号：US14076945

申请日：2013-11-11

申请人： Danisco US Inc.

发明人： Robert M. Caldwell ,  M. Harunur Rashid ,  Fernando Valle

IPC分类号： C12P7/58 ,  C12P7/00 ,  C12N9/02 ,  C12N15/00 ,  C12N1/20 ,  C07H21/04 ,  C12N15/78 ,  C12N15/74 ,  C12N9/06 ,  C12P7/60

CPC分类号： C12P7/58 ,  C12N9/0004 ,  C12N9/002 ,  C12N15/74 ,  C12N15/78 ,  C12P7/60

摘要： Described herein are multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate. The complexes comprise a dehydrogenase subunit and a cytochrome C subunit. Also described are polynucleotides coding for the multimeric complexes and methods of use thereof.

摘要翻译： 本文描述的是在碳底物的酶转化中起作用的多聚体氧化还原酶复合物。 复合物包含脱氢酶亚基和细胞色素C亚基。 还描述了编码多聚体复合物的多核苷酸及其使用方法。

公开(公告)号：US08835147B2

公开(公告)日：2014-09-16

申请号：US12935983

申请日：2009-04-03

申请人： Tae Seok Moon ,  Sang-Hwal Yoon ,  Kristala Lanett Jones Prather

发明人： Tae Seok Moon ,  Sang-Hwal Yoon ,  Kristala Lanett Jones Prather

IPC分类号： C12N9/04 ,  C12N15/63 ,  C12N1/20 ,  C12P33/02 ,  C12P21/00 ,  C12N15/82 ,  C12P7/58 ,  C12N9/90 ,  C12P19/02 ,  C12P19/00 ,  C12N9/02

CPC分类号： C12P7/58 ,  C12N9/0006 ,  C12N9/0069 ,  C12N9/90 ,  C12N15/8243 ,  C12N15/8245 ,  C12P19/00 ,  C12P19/02 ,  C12Y101/01203 ,  C12Y113/99001 ,  C12Y505/01004

摘要： The invention relates to the production of glucuronic and glucaric acid in cells through recombinant expression of myo-inositol 1-phosphate synthase, myo-inositol oxygenase and uronate dehydrogenase. Cloning and characterization of the gene encoding uronate dehydrogenase is also disclosed.

摘要翻译： 本发明涉及通过肌醇-1-磷酸合酶，肌醇加氧酶和糖醛酸脱氢酶的重组表达在细胞中生产葡萄糖醛酸和葡糖二酸。 还公开了编码糖醛酸脱氢酶的基因的克隆和表征。

公开(公告)号：US20140193870A1

公开(公告)日：2014-07-10

申请号：US14201733

申请日：2014-03-07

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： William T. BEESON, IV ,  James H. DOUDNA CATE ,  Michael A. MARLETTA

IPC分类号： C12P7/58

CPC分类号： C12P19/02 ,  A23K10/14 ,  A23K50/30 ,  A23K50/75 ,  C11D3/386 ,  C12N9/18 ,  C12P7/58 ,  C12P2201/00 ,  C12Y101/03004 ,  C12Y101/99018 ,  C12Y301/01017 ,  D21C5/00 ,  D21C5/005

摘要： The present disclosure relates to hydrolysis of hexose-δ-lactones by use of an S. thermophile extracellular aldonolactonase. In particular the present disclosure relates to compositions including a S. thermophile extracellular aldonolactonase and methods of use thereof.

摘要翻译： 本公开内容涉及通过使用嗜热脂肪酶胞外aldonolactonase水解己糖-δ-内酯。 特别地，本公开涉及包含嗜热链球菌细胞外α-淀粉酶的组合物及其使用方法。

公开(公告)号：US20140147907A1

公开(公告)日：2014-05-29

申请号：US14169174

申请日：2014-01-31

申请人： XYLECO, INC.

发明人： Marshall Medoff ,  Thomas Craig Masterman

IPC分类号： C12P19/02

CPC分类号： C12P7/10 ,  C07H3/02 ,  C07H3/04 ,  C12N1/20 ,  C12N1/38 ,  C12P5/02 ,  C12P7/04 ,  C12P7/06 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/52 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P7/6409 ,  C12P19/02 ,  C12P2201/00 ,  C12P2203/00 ,  Y02E50/16 ,  Y02E50/17 ,  Y02E50/343

摘要： Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to proceed ethanol and/or butanol, e.g., by fermentation.

摘要翻译： 加工生物质（例如，植物生物量，动物生物质和城市废物生物质）以产生有用的产物，例如燃料。 例如，系统可以使用原料，例如纤维素和/或木质纤维素材料，例如通过发酵来进行乙醇和/或丁醇。