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公开(公告)号：US09717088B2
公开(公告)日：2017-07-25
申请号：US14852461
申请日：2015-09-11
Inventor： Martin Reisslein , Frank James
IPC: H04W40/24 , H04W72/04 , H04L12/721 , H04L12/741 , H04W84/12
CPC classification number: H04W72/0453 , H04L45/66 , H04L45/74 , H04W40/24 , H04W84/12
Abstract: A multi-nodal wireless communication system comprises a system controller configured to create a link layer communication network. The system controller comprises a set of hardware finite state machines configured to receive a frame from a device associated with the link layer communication network as a request for data transmission, identify that the frame includes a unique ID value, transmit the unique ID value to an associated hardware queue, the hardware queue configured to construct at least one frame header associated with a base station to facilitate data transmission between the base station and the first device or between the first device and the network using one frame header, and process the frame in the link layer communication network by facilitating communication between the first device and the base station using the at least one frame header or between the first device and the network using one frame header.
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42.发明授权Reducing short-chain fatty acids and energy uptake in obese humans by managing their intestinal microbial communities 有权通过管理肠道微生物群落，减少肥胖人群的短链脂肪酸和能量摄入公开(公告)号：US09549955B2
公开(公告)日：2017-01-24
申请号：US14204757
申请日：2014-03-11
Inventor： Bruce Edward Rittmann , Rosa Krajmalnik-Brown , Husen Zhang , John Dibaise , Michael Crowell
IPC: A61K35/74 , A61K35/741 , A61K31/135 , A61K31/185 , A61K31/405 , A61K45/00
CPC classification number: A61K35/741 , A61K31/135 , A61K31/185 , A61K31/405 , A61K35/74 , A61K45/00 , A61K2300/00
Abstract: The present invention provides for microbial compositions and methods for reducing the concentration of short-chain fatty acids in the gut as a way to reduce energy uptake and manage obesity. More specifically, the invention provides for decreasing short-chain fatty acids available for absorption in the human gut, such as acetate, using one or more of: a probiotic including a homo-acetogenic, acetate oxidizing bacterium that converts acetate to H2; a probiotic including an acetoclastic methanogen; a microbial electrolysis cell comprising a homo-acetogenic bacterium and/or an acetoclastic methanogen; a prebiotic that enhances the growth or function of acetate-scavenging microbiota; or a highly selective antibiotic that targets H2-oxidizing methanogens.
Abstract translation: 本发明提供了减少肠道中短链脂肪酸浓度的微生物组合物和方法，作为减少能量吸收和控制肥胖症的一种方法。 更具体地，本发明提供了使用以下一种或多种方法减少可用于人类肠道例如乙酸盐的吸收的短链脂肪酸：益生菌，其包括将乙酸酯转化为H 2的同型乙酰乙酸氧化细菌; 益生菌，包括乙酰丙酸甲酯菌; 微生物电解池，包含同型乙型肝炎细菌和/或乙酰丙酸菌产甲烷菌; 提高乙酸盐清除微生物的生长或功能的益生元; 或靶向H2-氧化产甲烷菌的高选择性抗生素。
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43.发明申请公开(公告)号：US20160362384A1
公开(公告)日：2016-12-15
申请号：US15121669
申请日：2015-02-27
Inventor： Peiming ZHANG , Stuart LINDSAY , Sovan BISWAS , Suman SEN
IPC: C07D249/10 , G01N27/327 , C07C319/12
CPC classification number: C07D249/10 , C07C319/12 , G01N27/3276
Abstract: Triazole-based molecules, methods of making and using the same are provided. Triazole-based molecules may be used as reading molecules and incorporated into or operatively-linked with electrodes, for example, and used in recognition tunneling systems to identify individual and/or sequences of molecules (e.g., DNA bases, carbohydrates, proteins, peptides, and/or amino-acids).
Abstract translation: 提供了基于三唑的分子，制备和使用它们的方法。 三唑基分子可以用作阅读分子并且被掺入或与电极有电连接，并且用于识别隧道系统以识别分子的个体和/或序列（例如，DNA碱基，碳水化合物，蛋白质，肽， 和/或氨基酸）。
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公开(公告)号：US09413269B2
公开(公告)日：2016-08-09
申请号：US14410617
申请日：2013-06-25
Inventor： Rajapandian Ayyanar
CPC classification number: H02M7/537 , H02J3/383 , H02J3/385 , H02M1/15 , H02M7/48 , H02M7/487 , Y02E10/563 , Y02E10/58
Abstract: Circuits and methods for photovoltaic inverters are provided. In some embodiments, a power inverter circuit is provided, the inverter comprising: an input terminal for a direct current source coupled to a first conductor; a first side of a capacitor coupled to the input terminal; a second input terminal for the direct current source coupled to first sides of a first switch and second switch; a second side of the capacitor coupled to first sides of a third switch and fourth switch; a first side of a first inductor coupled to the first input terminal, the first side of the capacitor and the first conductor; a second side of the first inductor coupled to second sides of the first switch and third switch; and a first side of a second inductor coupled to a second conductor, and second sides of the second switch and fourth switch.
Abstract translation: 提供光伏逆变器的电路和方法。 在一些实施例中，提供了一种功率逆变器电路，所述逆变器包括：用于耦合到第一导体的直流电源的输入端子; 耦合到所述输入端子的电容器的第一侧; 用于直流电源的第二输入端，耦合到第一开关和第二开关的第一侧; 电容器的第二侧耦合到第三开关和第四开关的第一侧; 耦合到第一输入端子的第一电感器的第一侧，电容器的第一侧和第一导体; 所述第一电感器的第二侧耦合到所述第一开关和第三开关的第二侧; 以及耦合到第二导体的第二电感器的第一侧和第二开关和第四开关的第二侧。
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公开(公告)号：US20160038615A1
公开(公告)日：2016-02-11
申请号：US14776578
申请日：2014-03-14
Inventor： Sidney Hecht , Manikandadas Mathilakathu Madathil , Chandrabali Bhattacharya , Trevor Bozeman , Rakesh Paul , Zhiqiang Yu , Michael J. Rishel
CPC classification number: A61K49/0052 , A61B5/0071 , A61K47/545 , A61K47/6925 , A61K49/0002 , A61K49/0032 , A61K49/0054 , A61K49/223 , A61K51/0497 , A61K51/065
Abstract: This invention relates to compounds comprising a saccharide conjugated to an imaging agent or a reporter group, compositions comprising them and methods of using them. Specifically BLM-disaccharide and BLM-monosaccharide conjugates containing different linker groups and an imaging agent or a reporter group are provided for the targeting and imaging of tumors.
Abstract translation: 本发明涉及包含与成像剂或报告基团共轭的糖的化合物，包含它们的组合物和使用它们的方法。 具体地提供含有不同接头基团的BLM-二糖和BLM-单糖共轭物，以及成像剂或报告基团用于肿瘤的靶向和成像。
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Patent Agency Ranking
46.发明授权Longest prefix match internet protocol content addressable memories and related methods 有权最长的前缀匹配互联网协议内容可寻址的记忆和相关方法公开(公告)号：US09159421B2
公开(公告)日：2015-10-13
申请号：US14219787
申请日：2014-03-19
Inventor： Satendra Kumar Maurya , Lawrence T. Clark
IPC: G11C15/04 , G11C15/00 , H04L12/743 , H04L12/745 , G06F7/74
CPC classification number: G11C15/046 , G06F7/74 , G06F2213/0038 , G11C15/00 , G11C15/04 , H04L45/7457 , H04L45/748
Abstract: Embodiments of content addressable memories for internet protocol devices and operations are described herein. Other examples and related methods are also disclosed herein.
Abstract translation: 本文描述了用于因特网协议设备和操作的内容可寻址存储器的实施例。 本文还公开了其它实例和相关方法。
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公开(公告)号：US09152926B2
公开(公告)日：2015-10-06
申请号：US14376181
申请日：2013-02-04
Inventor： Jianming Liang , Hong Wu , Wenzhe Xue , Nima Tajbakhsh
CPC classification number: G06N99/005 , G06F19/321 , G06K9/6256 , G06K9/6267 , G06N5/043 , G06N5/046 , G16H50/20
Abstract: Systems, methods, and media for updating a classifier are provided, in some embodiments, systems for updating a classifier are provided, the systems comprising: a hardware processor that is configured to: receive a sample; for each of a first plurality of weak learners, classify the sample using the weak learner, determine an outcome of the classification, and determine an up-dated error rate of the weak learner based on the outcome of the classification and at least one of: (i) a count of positive samples used to update the classifier, and (ii) a count of negative samples used to update the classifier; select a first weak learner from the first plurality of weak learners based on the updated error rate of the first weak learner; and update tire classifier based on the first weak learner.
Abstract translation: 提供了用于更新分类器的系统，方法和媒体，在一些实施例中，提供了用于更新分类器的系统，所述系统包括：硬件处理器，其被配置为：接收样本; 对于第一多个弱学习者中的每一个，使用弱学习者对样本进行分类，确定分类的结果，并且基于分类结果确定弱学习者的更新错误率，并且至少以下之一： （i）用于更新分类器的正样本的计数，以及（ii）用于更新分类器的负样本的计数; 基于第一弱势学习者的更新错误率，从第一批弱势学习者中选出第一位弱势学习者; 并基于第一个弱学习者更新轮胎分选机。
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公开(公告)号：US20150209109A1
公开(公告)日：2015-07-30
申请号：US14413822
申请日：2013-08-09
Inventor： Kaushal Rege , Huang-Chiao Huang
CPC classification number: A61B18/203 , A61B18/14 , A61B18/18 , A61B18/20 , A61B2018/00404 , A61B2018/00452 , A61B2018/00494 , A61B2018/00505 , A61B2018/0063 , A61B2018/1807 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1841 , A61K38/19 , A61K38/39 , A61K41/0052 , A61L24/0005 , A61L24/0015 , A61L24/0089 , A61L24/108 , A61L2300/404 , A61L2300/414 , A61L2400/12 , A61N5/062 , A61N2005/067 , A61K2300/00 , C08L89/00
Abstract: Disclosed herein are methods of connecting disrupted tissue, tissue repair, treating colorectal disorder and tissue welding. The methods comprise using a bioadhesive composition comprising ELP and light absorbing chromophores and irradiating the bioadhesive tissue.
Abstract translation: 本文公开了连接破裂的组织，组织修复，治疗结肠直肠疾病和组织焊接的方法。 所述方法包括使用包含ELP和光吸收发色团并照射生物粘附组织的生物粘合剂组合物。
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49.发明申请PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING DRUG ADDICTION AND PREVENTING A DRUG RELAPSE 审中-公开药物组合物和治疗药物滥用和预防药物相关的方法公开(公告)号：US20150141462A1
公开(公告)日：2015-05-21
申请号：US14407650
申请日：2013-06-11
Inventor： M. Foster Olive
IPC: A61K31/444 , A61K45/06 , A61K31/415
CPC classification number: A61K31/444 , A61K31/415 , A61K45/06 , A61K2300/00
Abstract: The present invention relates to pharmaceutical compositions comprising (a) a pharmaceutically effective amount of an mGluR5 positive allosteric modulator, derivative, prodrug or a pharmaceutically acceptable salt thereof; (b) a pharmaceutically effective amount of an agent selected from an NMDA partial agonist or a GlyT1 inhibitor, derivative, prodrug or a pharmaceutically acceptable salt thereof; and (c) a pharmaceutically acceptable carrier. The present invention also relates to methods for treating drug addiction and preventing a drug relapse in a patient. The methods comprise (a) administering to the patient a pharmaceutically effective amount of an mGluR5 positive allosteric modulator, derivative, prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof; (b) administering to the patient a pharmaceutically effective amount of an agent selected from an NMDA partial agonist or a GlyT1 inhibitor, derivative, prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof.
Abstract translation: 本发明涉及药物组合物，其包含（a）药学有效量的mGluR5阳性变构调节剂，其衍生物，前药或其药学上可接受的盐; （b）药学有效量的选自NMDA部分激动剂或GlyT1抑制剂，衍生物，前药或其药学上可接受的盐的药剂; 和（c）药学上可接受的载体。 本发明还涉及治疗药物成瘾和预防患者药物复发的方法。 所述方法包括（a）向患者施用药学有效量的mGluR5阳性变构调节剂，其衍生物，前药或其药学上可接受的盐或其药物组合物; （b）向患者施用药学有效量的选自NMDA部分激动剂或GlyT1抑制剂，衍生物，前药或其药学上可接受的盐或其药物组合物。
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公开(公告)号：US08858440B2
公开(公告)日：2014-10-14
申请号：US14025586
申请日：2013-09-12
Inventor： William James P. Tyler
CPC classification number: A61N7/00 , A61B5/0476 , A61B5/4836 , A61N5/0613 , A61N5/062 , A61N5/0622 , A61N2005/0651 , A61N2005/0652 , A61N2005/0653 , A61N2005/067 , A61N2007/0021 , A61N2007/0026 , A61N2007/0073 , A61N2007/0078 , C12N5/0619 , C12N13/00
Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.
Abstract translation: 本发明包括用于调节活细胞的活性或活性的方法和装置，例如在人，动物，植物，昆虫，微生物和其他生物体中发现或衍生的细胞。 本发明的方法包括使用超声波（例如低强度，低频超声波）对活细胞的应用来影响细胞并调节细胞的活性。 本发明的装置包括用于产生超声波的一个或多个部件，例如超声波发射器，换能器或压电换能器，复合换能器，CMUT，并且其可被提供为单个或多个换能器或阵列配置。 超声波可以是任何形状，并且可以被聚焦或未被聚焦。
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