Chalaropsis Lysozyme Protein and its Method of Use in Anti-Bacterial Applications
    42.
    发明申请
    Chalaropsis Lysozyme Protein and its Method of Use in Anti-Bacterial Applications 失效
    Chalaropsis溶菌酶蛋白及其在抗细菌应用中的应用方法

    公开(公告)号:US20070253945A1

    公开(公告)日:2007-11-01

    申请号:US10566243

    申请日:2004-07-30

    Abstract: A Chalaropsis lysozyme (Lysozyme Ch) is provided which has a corrected amino acid sequence and which can be utilized to prepare recombinant proteins having higher activity than those proteins prepared using the incorrect sequence. Methods are also provided to reduce immunogenicity or increase half-life of the lysozyme. The lysozyme Ch of the present invention will be extremely useful in killing bacteria, particularly resistance strains such as MRSA and VISA, and the enzyme can be utilized in a variety of settings wherein bacterial infection has been a particular problem such as the hospital setting or in veterinary applications, and can also be used as an effective means of combating bioterror agents.

    Abstract translation: 提供了具有校正的氨基酸序列并可用于制备比使用不正确序列制备的蛋白质具有更高活性的重组蛋白质的拟南芥溶菌酶(溶菌酶Ch)。 还提供了降低免疫原性或增加溶菌酶半衰期的方法。 本发明的溶菌酶Ch对于杀灭细菌,特别是抗性菌株如MRSA和VISA是非常有用的,并且该酶可用于多种情况,其中细菌感染已经是特定的问题,例如医院环境或 兽医应用,也可用作打击生物恐怖剂的有效手段。

    Centrifugal pump with hydrodynamic bearing and double involute
    43.
    发明申请
    Centrifugal pump with hydrodynamic bearing and double involute 审中-公开
    离心泵带流体动力轴承和双渐开线

    公开(公告)号:US20070077155A1

    公开(公告)日:2007-04-05

    申请号:US11241624

    申请日:2005-09-30

    CPC classification number: F04D29/047 F04D13/0646

    Abstract: A centrifugal pump with a hydrodynamic bearing and a double involute is disclosed. Some embodiments may include an impeller housing comprising a fluid entrance to allow fluid to enter and an impeller located within the impeller housing, the impeller comprising a plurality of impeller blades, a plurality of fluid channels between the impeller blades, and a motor magnet. The impeller may rotate within the impeller housing about a pump centerline in response to an electromagnetic field and the fluid channels may each allow fluid to pass through when the impeller rotates. Embodiments may also include one or more hydrodynamic bearings positioned between the impeller and the impeller housing to support generated loads and a double involute coupled with the impeller housing and positioned to receive fluid exiting the plurality of fluid channels. Further embodiments may include a motor stator to generate the electromagnetic field. Other embodiments are disclosed and claimed.

    Abstract translation: 公开了一种具有流体动力轴承和双渐开线的离心泵。 一些实施例可以包括叶轮壳体,其包括允许流体进入的流体入口和位于叶轮壳体内的叶轮,叶轮包括多个叶轮叶片,叶轮叶片之间的多个流体通道和马达磁体。 叶轮可以响应于电磁场而围绕泵中心线在叶轮壳体内旋转,并且当叶轮旋转时,流体通道可以允许流体通过。 实施例还可以包括定位在叶轮和叶轮壳体之间的一个或多个流体动力轴承,以支撑所产生的负载,以及与叶轮壳体联接并定位成接收离开多个流体通道的流体的双渐开线。 另外的实施例可以包括用于产生电磁场的电动机定子。 公开和要求保护其他实施例。

    Media timing based on stack height for use within an image forming device
    45.
    发明申请
    Media timing based on stack height for use within an image forming device 有权
    基于在图像形成装置内使用的堆叠高度的介质定时

    公开(公告)号:US20070052155A1

    公开(公告)日:2007-03-08

    申请号:US11221459

    申请日:2005-09-08

    Abstract: Methods and devices for moving media sheets through an image forming device. A sensor is positioned within an input area to determine a height of a media stack. When the media stack is full, a top-most sheet of the media stack is physically closer to the beginning point of the media path. When the media stack is depleted, the top-most sheet is positioned a further distance away from the beginning point. Movement of the media sheet is determined based on the height of the media stack. When the media stack is above a predetermined amount, the media sheet is moved according to a first algorithm. When the media stack is below the predetermined amount, the media sheet is moved according to a second algorithm.

    Abstract translation: 用于通过图像形成装置移动介质片的方法和装置。 传感器位于输入区域内以确定介质堆的高度。 当媒体堆栈已满时,媒体堆栈的最顶层物理距离媒体路径的起点更接近。 当媒体堆栈耗尽时,最顶层的纸张距离起点更远一些。 基于介质堆的高度确定介质片的移动。 当介质堆叠高于预定量时,根据第一算法移动介质片。 当介质堆叠低于预定量时,根据第二算法移动介质片。

    Image Forming Device with Multimode Duplexer
    46.
    发明申请
    Image Forming Device with Multimode Duplexer 有权
    具有多模双工器的图像形成装置

    公开(公告)号:US20070014610A1

    公开(公告)日:2007-01-18

    申请号:US11532931

    申请日:2006-09-19

    CPC classification number: G03G15/234 G03G2215/00586 G03G2215/0119

    Abstract: An image forming device in a color printer or the like includes duplex printing. Multiple media sheets are moved through a media path which includes a primary path and a duplex path. Various parameters of the image forming device control the interpage gap between sheets. Parameters include peek-a-boo duplexing, sharing of motors within the drive rollers, and sharing of power supplies.

    Abstract translation: 彩色打印机等中的图像形成装置包括双面打印。 通过包括主路径和双工路径的媒体路径移动多个媒体片。 图像形成装置的各种参数控制片材之间的间隙。 参数包括窥视双工,驱动辊内的电机共享,以及电源的共享。

    Systems for integrated pump and reservoir
    47.
    发明申请
    Systems for integrated pump and reservoir 有权
    集成泵和水库系统

    公开(公告)号:US20070000268A1

    公开(公告)日:2007-01-04

    申请号:US11170427

    申请日:2005-06-29

    CPC classification number: H01L23/473 F04D29/588 H01L2924/0002 H01L2924/00

    Abstract: According to some embodiments, systems for an integrated pump and reservoir may be provided. In some embodiments, a pump may comprise a housing defining an inlet to accept a fluid and an outlet to evacuate the fluid, an impeller disposed within the housing, wherein the impeller is to move the fluid toward the outlet, a motor to power the impeller, a reservoir hydraulically coupled to the inlet, and a cold plate disposed at least partially within the housing.

    Abstract translation: 根据一些实施例,可以提供用于集成泵和储存器的系统。 在一些实施例中,泵可以包括限定入口以接收流体的外壳和排出流体的出口,设置在壳体内的叶轮,其中叶轮将流体朝向出口移动,电动机为叶轮供电 液压耦合到入口的储液器,以及至少部分地设置在壳体内的冷板。

    Systems for low cost liquid cooling
    48.
    发明申请
    Systems for low cost liquid cooling 有权
    低成本液体冷却系统

    公开(公告)号:US20060144570A1

    公开(公告)日:2006-07-06

    申请号:US11027417

    申请日:2004-12-31

    Abstract: According to some embodiments, systems for low cost liquid cooling may be provided. In some embodiments, a system may comprise a core having a first end and a second end, wherein the core defines a cavity extending between the first and second ends, a plurality of fins extending outwardly from the core between the first and second ends, an inlet to accept a fluid, an outlet to evacuate the fluid, and a shaped element disposed within the cavity of the core, wherein the shaped element is to direct the fluid within the cavity. According to some embodiments, the system may further comprise a pump that may comprise a housing defining an inlet to accept the fluid and an outlet to evacuate the fluid, an impeller disposed within the housing, wherein the impeller is to move the fluid toward the outlet, a motor to power the impeller, and a cold plate disposed at least partially within the housing.

    Abstract translation: 根据一些实施例,可以提供用于低成本液体冷却的系统。 在一些实施例中,系统可以包括具有第一端和第二端的芯,其中所述芯限定在第一和第二端之间延伸的空腔,在第一和第二端之间从芯向外延伸的多个翅片, 入口以接收流体,排出流体的出口以及设置在芯的空腔内的成形元件,其中成形元件将流体引导到空腔内。 根据一些实施例,系统还可以包括泵,其可以包括限定入口以容纳流体的壳体和排出流体的出口,设置在壳体内的叶轮,其中叶轮将流体朝向出口 ,用于驱动叶轮的马达以及至少部分地设置在壳体内的冷板。

    Compliant media stack height limiter
    49.
    发明申请
    Compliant media stack height limiter 有权
    符合媒体堆栈高度限制器

    公开(公告)号:US20060043665A1

    公开(公告)日:2006-03-02

    申请号:US10925523

    申请日:2004-08-25

    CPC classification number: B65H1/04 B65H2301/4228 B65H2511/152 B65H2511/22

    Abstract: A method and apparatus for limiting the height of media inserted into a media tray of an image forming apparatus 10 while also allowing for the inserted media to expand due to changing environmental conditions is described herein. An exemplary stack height limiting system comprises an elongated arm with a striking end spaced from a control end, where the arm is movable between first and second positions. A limiter positioned relative to the arm defines the first position, where the striking end is spaced from the bottom surface of the tray by a first gap. As media disposed in the tray expands beyond the first gap, the expanding media moves the arm to form a second, greater distance between the striking end and the bottom surface of the tray. As a result, pinch points between the first end and the media are avoided.

    Abstract translation: 本文描述了一种用于限制插入图像形成装置10的介质托盘中的介质的高度的方法和装置,同时还允许插入的介质由于环境条件的变化而膨胀。 示例性堆叠高度限制系统包括细长臂,其具有与控制端间隔开的击打端,其中臂可在第一和第二位置之间移动。 相对于臂定位的限制器限定第一位置,其中击打端与托盘的底表面间隔开第一间隙。 当设置在托盘中的介质膨胀超过第一间隙时,膨胀介质移动臂以在打击端和托盘的底表面之间形成第二更大的距离。 结果,避免了第一端和介质之间的夹点。

    Human albumin animal models for drug evaluation, Toxicology and immunogenicity studies
    50.
    发明申请
    Human albumin animal models for drug evaluation, Toxicology and immunogenicity studies 审中-公开
    人白蛋白药物评价动物模型,毒理学和免疫原性研究

    公开(公告)号:US20060026701A1

    公开(公告)日:2006-02-02

    申请号:US11232989

    申请日:2005-09-23

    Applicant: Daniel Carter

    Inventor: Daniel Carter

    Abstract: An animal model is provided which is genetically engineered to express human serum albumin, and such animals may be advantageously used in assessing drugs, vaccines or other therapeutic compounds that may be used in humans. In addition, an animal model is provided which does not manufacture its own albumin and which has been injected with human serum albumin. Through the use of these animal models, drugs and other chemicals can be more accurately assessed in physiological environments that reflect the conditions to be expected in humans, and such models will be useful in assessing new drugs and evaluating toxic substances for potential dangers as carcinogens, mutagens, etc. Other applications include evaluating immunological properties of various albumin-engineered proteins which might be administered to humans as therapeutics or vaccines, and research of disease states, such as genetic diseases, to provide further insight in treating these diseases.

    Abstract translation: 提供了基因工程化以表达人血清白蛋白的动物模型,并且这样的动物可以有利地用于评估可用于人类的药物,疫苗或其它治疗化合物。 另外,提供了不生产自己的白蛋白并且已经注射人血清白蛋白的动物模型。 通过使用这些动物模型,可以在反映人类预期条件的生理环境中更准确地评估药物和其他化学品,并且这些模型将有助于评估新药物和评估有毒物质作为致癌物质的潜在危险, 诱变剂等。其他应用包括评估可能作为治疗剂或疫苗施用于人的各种白蛋白工程蛋白质的免疫学性质,以及疾病状态如遗传性疾病的研究,以提供治疗这些疾病的进一步洞察。

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