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    Mask-free photolithography using metastable undercooled metal particles
    41.
    发明授权
    Mask-free photolithography using metastable undercooled metal particles 有权

    公开(公告)号：US11633807B2

    公开(公告)日：2023-04-25

    申请号：US17092735

    申请日：2020-11-09

    Applicant: Iowa State University Research Foundation, Inc.

    Inventor： Martin Thuo ,  Peter C. Collins ,  Andrew Martin

    IPC: B23K26/342 ,  B33Y10/00 ,  B33Y80/00 ,  B33Y30/00 ,  B23K26/352 ,  B33Y70/00 ,  B23K26/00 ,  B23K26/08 ,  B23K26/06 ,  B33Y50/02

    Abstract: Various embodiments relate to forming particles using undercooled metal particles in response to focused low power laser light. Particle growth can be initiated by utilizing the metastable and liquid nature of the particles, allowing for surface instability promoted by the laser light to induce liquid flow to translate to a neighboring particle. This event can cascade radially leading to accumulation of the liquid metal at the epicenter. The grown solidified particle size can be varied by using different power, exposure time, or working distance. Once the liquid has accumulated into a single region, it eventually solidifies either through homogeneous or heterogeneous nucleation to give a solid particle of larger size than the original. Such a method can be used to print patterns on a surface in four dimensions, where the fourth dimension (4D) is attained through gradient in size of the particles made. Additional systems and methods are disclosed.

    USE OF DOPAMINE PRODUCING PRODUCTS TO INCREASE VACCINE EFFICACY
    42.
    发明申请
    USE OF DOPAMINE PRODUCING PRODUCTS TO INCREASE VACCINE EFFICACY 有权

    公开(公告)号：US20230111960A1

    公开(公告)日：2023-04-13

    申请号：US18045264

    申请日：2022-10-10

    Applicant: Iowa State University Research Foundation, Inc.

    Inventor： Mark Lyte

    IPC: A61K35/744 ,  A61K31/198 ,  A61K36/48 ,  A61K36/81 ,  A61P37/04

    Abstract: The present disclosure is directed to dopamine producing probiotics to increase immune responses to vaccination and to provide increased immune protection. The present disclosure is further directed to dopamine producing synbiotic compositions, formulations, plants, and synthetic compounds and their use for targeted clinical and veterinary applications, for example, in promoting health and well-being and enhancing vaccine efficacy. The present disclosure also provides an approach for optimization of synbiotic delivery of a probiotic or other dopamine producing product with a dopamine precursor to beneficially aid in the use of such products for a variety of conditions and diseases, and particularly in the field of vaccines, whether prophylactic or therapeutic.

    POSITION INDEPENDENT AND LONG READ RANGE RESONANT SENSOR
    43.
    发明申请
    POSITION INDEPENDENT AND LONG READ RANGE RESONANT SENSOR 有权

    公开(公告)号：US20230075934A1

    公开(公告)日：2023-03-09

    申请号：US17820753

    申请日：2022-08-18

    Applicant: Iowa State University Research Foundation, Inc.

    Inventor： Yee Jher Chan ,  Adam Russell Carr ,  Nigel Forest Reuel

    IPC: G01N27/22 ,  G01N33/24 ,  G01N27/02

    Abstract: An inductive-capacitive resonant sensor architecture includes an inductively-coupled extender (ICE) that can both increase read range and lessen the effects of reader/sensor misalignment. The ICE can include a first coil configured with respect to a resonant sensor and a second coil separated from the first coil and coupled to the first coil by electrical wires. An external reader can be arranged with respect to the second coil. This architecture can nearly eliminate misalignment issues between the external reader and the resonant sensor. The ICE can be implemented with a closed circuit design. Additional apparatus, systems, and methods are disclosed.

    Modification of transcriptional repressor binding site in NF-YC4 promoter for increased protein content and resistance to stress
    47.
    发明授权
    Modification of transcriptional repressor binding site in NF-YC4 promoter for increased protein content and resistance to stress 有权

    公开(公告)号：US11542520B2

    公开(公告)日：2023-01-03

    申请号：US16840354

    申请日：2020-04-04

    Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.

    Inventor： Ling Li ,  Eve Syrkin Wurtele

    IPC: C12N15/82 ,  C07K14/415 ,  A01H1/02

    Abstract: Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant cell or plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant cell or plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism, such as a plant, in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; plants and hybrids thereof; and seeds.

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