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    THE USE OF MECHANICAL (ACOUSTIC/SUBSONIC) VIBRATION FOR A NOVEL PARADIGM IN REGENERATIVE MEDICINE AND HUMAN WELL BEING
    41.
    发明申请
    THE USE OF MECHANICAL (ACOUSTIC/SUBSONIC) VIBRATION FOR A NOVEL PARADIGM IN REGENERATIVE MEDICINE AND HUMAN WELL BEING 审中-公开

    公开(公告)号：US20200181576A1

    公开(公告)日：2020-06-11

    申请号：US16315978

    申请日：2017-07-07

    申请人： James Ryan ,  Carlo Ventura

    发明人： James Ryan ,  Carlo Ventura

    IPC分类号： C12N5/077 ,  G01Q60/38 ,  G01J3/28

    摘要： Methods of acquiring cellular and tissue vibrational patterning to identify signatures capable to induce pluripotency and commitment towards defined lineages, as well as survival under hostile conditions (i.e. oxidative stress) in both human adult stem cells and human adult somatic cells are described. Specifically, the invention relates to the delivery of such signatures to human adult stem cells or human adult somatic cells to induce specific differentiation processes and promote survival to hostile environmental conditions. Further methods are described of targeting tissue resident in vivo to retrieve their ability to sustain self-healing process, therefore affording a Regenerative Medicine executed without the needs for (stem) cell or tissue transplantation.

    Player controls
    42.
    发明授权
    Player controls 有权
    玩家控制

    公开(公告)号：US09311770B2

    公开(公告)日：2016-04-12

    申请号：US13506254

    申请日：2012-04-06

    申请人： Phillip James Ryan

    发明人： Phillip James Ryan

    IPC分类号： G07F17/32

    CPC分类号： G07F17/3206 ,  G07F17/32 ,  G07F17/3237 ,  G07F17/3239

    摘要： The patent involves the use of a portable device with a universal serial bus connector and memory which can store the unique biometrics of its registered owner for the purposes of identification; record the biometrics of any person attempting to use the device; confirm whether the user is the registered owner of the device; control access to electronic devices; monitor and record the operational activity of its user; store pre-defined value, duration and budgetary constraints; compare activity to pre-defined values, durations and budgetary constraints; store monetary value; visually indicate when operative; be electronically locked and de-activated; and connect and communicate directly or remotely to other electronic devices.The device can be used for example in the identification and elimination of problem gamblers from gambling devices/services while either physically present at a gambling venue or through remote access via the internet, interactive television, intranets, extranets, telephones or other digital communication services.

    摘要翻译： 该专利涉及使用具有通用串行总线连接器和存储器的便携式设备，其可以存储其注册所有者的唯一生物特征以用于识别; 记录任何试图使用该设备的人的生物特征; 确认用户是否是设备的注册所有者; 控制电子设备的访问; 监控和记录其用户的操作活动; 存储预定价值，期限和预算限制; 将活动与预定义的价值观，持续时间和预算约束进行比较; 储存货币价值; 视觉上表明手术时间; 电子锁定和停用; 并直接或远程连接和通信到其他电子设备。 该设备可以用于例如在赌博设备/服务中识别和消除问题赌徒，或者通过互联网，互动电视，内联网，外联网，电话或其他数字通信服务实时存在于赌场或通过远程访问。

    Social network system and method of operation
    43.
    发明授权
    Social network system and method of operation 有权
    社会网络系统和操作方法

    公开(公告)号：US09305318B2

    公开(公告)日：2016-04-05

    申请号：US13009819

    申请日：2011-01-19

    申请人： Grant James Ryan ,  Gary Lee Franklin ,  Julian Malcolm Cone ,  William Ferguson Stalker ,  Derick Ian Robinson

    发明人： Grant James Ryan ,  Gary Lee Franklin ,  Julian Malcolm Cone ,  William Ferguson Stalker ,  Derick Ian Robinson

    IPC分类号： G06F15/16 ,  G06Q50/00 ,  H04L12/58 ,  G06Q99/00 ,  G06Q10/10

    CPC分类号： G06Q50/01 ,  G06Q10/1053 ,  G06Q30/0214 ,  G06Q99/00 ,  H04L51/20 ,  H04L51/32 ,  H04L63/08

    摘要： A method of forming unique, private, personal, virtual social networks on a social network system that includes a database storing data relating to corresponding user entities. The method includes: a first user entity sending an invitation to a second user entity, recording in the database the second user entity as a direct contact of the first user entity and determining that third user entities, directly connected to the second user entity, are indirect contacts. A unique, personal, social network formed from direct and indirect contacts is thereby created for each user entity. Each user entity is able to control privacy of its data with respect to other user entities depending on the connection factor to that other entity and/or that other entity's attributes.

    摘要翻译： 一种在社交网络系统上形成唯一的，私人的，个人的，虚拟的社交网络的方法，其包括存储与相应用户实体有关的数据的数据库。 该方法包括：向第二用户实体发送邀请的第一用户实体，在数据库中记录第二用户实体作为第一用户实体的直接联系，并确定直接连接到第二用户实体的第三用户实体是 间接联系 因此，为每个用户实体创建由直接和间接联系形成的独特的个人社交网络。 每个用户实体能够根据与该另一实体的连接因素和/或该其他实体的属性来控制其数据相对于其他用户实体的隐私。

    Method and system for sealing a dovetail
    44.
    发明授权
    Method and system for sealing a dovetail 有权
    用于密封燕尾榫的方法和系统

    公开(公告)号：US08985960B2

    公开(公告)日：2015-03-24

    申请号：US13075999

    申请日：2011-03-30

    申请人： James Ryan Connor ,  Mark Steven Honkomp

    发明人： James Ryan Connor ,  Mark Steven Honkomp

    IPC分类号： F01D5/30 ,  F01D11/00 ,  F16J15/08

    CPC分类号： F01D5/3007 ,  F01D11/006 ,  F05D2250/71 ,  F16J15/0887

    摘要： A method and system for sealing a gap between a bucket dovetail and a rotor is provided. The dovetail seal includes a first end portion extending from a first extent of the first end portion a predetermined distance along a length of the dovetail seal, a second end portion extending from a first extent of the second end portion a predetermined distance along a length of the dovetail seal towards the first end portion, and a body extending between the first and second end portions. The body includes a U-shaped bend complementary to a sealing groove in a dovetail of a turbine blade. The first end portion includes a converging flared cross-section from the first extent of the first end portion toward the second end portion and the second end portion includes a converging flared cross-section from the first extent of the second end portion toward the first end portion.

    摘要翻译： 提供了一种用于密封桶形燕尾榫和转子之间的间隙的方法和系统。 燕尾形密封件包括第一端部部分，该第一端部部分从第一端部的第一部分沿着燕尾形密封件的长度延伸预定距离，第二端部部分从第二端部的第一部分延伸一段预定距离， 朝向第一端部的燕尾形密封件，以及在第一和第二端部之间延伸的本体。 主体包括与涡轮叶片的燕尾榫中的密封槽互补的U形弯曲。 第一端部包括从第一端部的第一部分朝向第二端部的会聚的喇叭形横截面，并且第二端部包括从第二端部的第一部分朝向第一端部的会聚的展开的横截面 一部分。

    Using non-public shipper records to facilitate rating an entity based on public records of supply transactions
    45.
    发明授权
    Using non-public shipper records to facilitate rating an entity based on public records of supply transactions 有权
    使用非公开托运人记录，以便根据供应交易的公开记录对实体进行评级

    公开(公告)号：US08626618B2

    公开(公告)日：2014-01-07

    申请号：US13343354

    申请日：2012-01-04

    申请人： James Ryan Psota ,  Joshua Green

    发明人： James Ryan Psota ,  Joshua Green

    IPC分类号： G06Q30/00

    CPC分类号： G06Q50/28 ,  G06Q10/10 ,  G06Q30/02 ,  G06Q30/06

    摘要： A platform facilitates buyers, sellers, and third parties in obtaining information related to each other's transaction histories, such as a supplier's shipment history, the types of materials typically shipped, a supplier's customers, a supplier's expertise, what materials and how much a buyer purchases, buyer and shipper reliability, similarity between buyers, similarity between suppliers, and the like. The platform aggregates data from a variety of sources, including, without limitation, customs data associated with actual import/export transactions, non-public shipper records, and facilitates the generation of reports as to the quality of buyers and suppliers, the reports relating to a variety of parameters that are associated with buyer and supplier quality.

    摘要翻译： 一个平台便于买方，卖方和第三方获取与彼此的交易历史相关的信息，例如供应商的出货历史，通常运送的材料类型，供应商的客户，供应商的专业知识，什么材料以及买方购买的数量 ，买方和托运人的可靠性，买方之间的相似性，供应商之间的相似性等。 该平台汇集了各种来源的数据，包括但不限于与实际进出口交易相关的海关数据，非公开托运人记录，并有助于生成有关买方和供应商质量的报告。 与买方和供应商质量相关的各种参数。

    Linear motion delivery system for female sterilization device
    47.
    发明授权
    Linear motion delivery system for female sterilization device 失效
    用于女性消毒装置的直线运动传送系统

    公开(公告)号：US08562628B2

    公开(公告)日：2013-10-22

    申请号：US11695887

    申请日：2007-04-03

    申请人： James Ryan Mujwid ,  Kevin R. Arnal

    发明人： James Ryan Mujwid ,  Kevin R. Arnal

    IPC分类号： A61D1/06 ,  A61M29/00 ,  A61F2/06

    CPC分类号： A61F6/06 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12172 ,  A61B17/12177 ,  A61B2017/1205 ,  A61F6/225

    摘要： A delivery system for deploying an occlusion device comprises a piston having a threaded proximal end, an elongated delivery catheter having a proximal end, a distal end, and an inner lumen extending between the proximal and distal ends of the delivery catheter, and a drive mechanism comprising an internally threaded nut member and a spring member. The piston is moveable between a first axial position and a second axial position. The internally threaded nut member receives the threaded proximal end of the piston. The spring member, which is coupled to the internally threaded nut member, rotates the nut member to drive the piston from the first axial position toward the nut member to the second axial position. Driving the piston toward the nut member retracts the attached delivery catheter and deploys an occlusion device from within the inner lumen and through the distal end of the delivery catheter.

    摘要翻译： 用于展开闭塞装置的输送系统包括具有螺纹近端的活塞，具有近端，远端以及在输送导管的近端和远端之间延伸的内腔的细长输送导管，以及驱动机构 包括内螺纹螺母构件和弹簧构件。 活塞可在第一轴向位置和第二轴向位置之间移动。 内螺纹螺母构件接收活塞的螺纹近端。 联接到内螺纹螺母构件的弹簧构件使螺母构件旋转，以将活塞从第一轴向位置朝向螺母构件驱动到第二轴向位置。 将活塞向着螺母部件驱动缩回所附接的输送导管，并从内腔内部和穿过输送导管的远端部署闭塞装置。

    Isolated SNARE YKT6 genomic polynucleotide fragments from chromosome 7 and their uses
    50.
    发明授权
    Isolated SNARE YKT6 genomic polynucleotide fragments from chromosome 7 and their uses 有权
    来自染色体7的分离的SNARE YKT6基因组多核苷酸片段及其用途

    公开(公告)号：US08323884B2

    公开(公告)日：2012-12-04

    申请号：US12533130

    申请日：2009-07-31

    申请人： James Ryan

    发明人： James Ryan

    IPC分类号： C12Q1/68 ,  C12P21/06 ,  C07H21/00 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C12Q1/6876 ,  A61K38/00 ,  C07K14/705 ,  C12N9/1205 ,  C12N9/1241 ,  C12N9/48 ,  Y10T436/143333

    摘要： The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

    摘要翻译： 本发明涉及编码人类SNARE YKT6，人类葡萄糖激酶，人类脂肪细胞增强子结合蛋白（AEBP1）和定向的50kD调节亚基（POLD2）的DNA的分离的基因组多核苷酸片段，含有这些片段的载体和宿主以及与非编码区杂交的片段 以及这些片段的反义寡核苷酸。 本发明进一步涉及使用这些片段获得SNARE YKT6，人类葡萄糖激酶，AEBP1蛋白和POLD2并诊断，治疗，预防和/或改善病理性疾病的方法。