摘要:
A composition for intranasal delivery of a drug comprising: includes: (i) the drug; and (ii) a non-aqueous vehicle containing (a) propylene glycol and at least one additional solvent selected from N-methylpyrrolidone, propylene carbonate, dimethyl sulfoxide and at least one propylene glycol fatty acid ester; (b) from about 40 to 100% by volume of N-methylpyrrolidone; or (c) from about 40 to 100% by volume of dimethyl sulfoxide (DMSO).
摘要:
A technique comprising: securing a device substrate (8) to a carrier (1) using one or more adhesive elements (6); forming electronic elements (10) on the device substrate with the device substrate thus secured to the carrier; and thereafter reducing the adhesion strength of at least one of the one or more adhesive elements to facilitate the release of the substrate from the carrier.
摘要:
A technique comprising: assembling together a front plane (1) comprising a first flexible substrate (4) supporting a display medium (6a) and a backplane (2) comprising a second flexible substrate (8) supporting an array of electronic elements (9) for controlling said display medium; and creating an electrically conductive connection between first and second conductive elements (5 10) on opposing faces of the frontplane and backplane by sandwiching an electrically conductive structure (3) between the frontplane and backplane in the region of the first and second conductive elements, wherein the conductive structure is at least more flexible than the least flexible one of the front plane and backplane.
摘要:
A composition for the intranasal delivery of fentanyl or a pharmaceutically acceptable salt thereof to an animal includes an aqueous solution of fentanyl or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable additive selected from (i) a pectin and (ii) a poloxamer and chitosan or a salt or derivative thereof; provided that when the composition comprises a pectin it is substantially free of divalent metal ions; and which, in comparison to a simple aqueous solution of fentanyl administered intranasally at the same dose, provides a peak plasma concentration of fentanyl (Cmax) that is from 10 to 80% of that achieved using a simple aqueous solution of fentanyl administered intranasally at an identical fentanyl dose. A method for treating or managing pain by intranasally administering the composition is also disclosed.
摘要:
A cutting platform for use with an agricultural harvesting machine includes at least one platform section having a frame, a plurality of float arms movably coupled with the frame, an endless belt carried by the plurality of float arms, a cutterbar assembly carried by the plurality of float arms, and a plurality of crop ramps extending from the cutterbar assembly. The plurality of crop ramps are movable relative to each other and overly a leading edge of the endless belt. The endless belt and the cutterbar assembly are movable in a localized manner across the cutting platform in upwards and downwards directions.
摘要:
A composition for intranasal delivery of a drug comprising: includes: (i) the drug; and (ii) a non-aqueous vehicle containing (a) propylene glycol and at least one additional solvent selected from N-methylpyrrolidone, propylene carbonate, dimethyl sulfoxide and at least one propylene glycol fatty acid ester; (b) from about 40 to 100% by volume of N-methylpyrrolidone; or (c) from about 40 to 100% by volume of dimethyl sulfoxide (DMSO).
摘要:
A cutting platform for use with an agricultural harvesting machine includes a plurality of platform sections positioned in end-to-end juxtaposed relation to each other. At least one platform section includes a frame, a plurality of float arms movably coupled with the frame, an endless belt carried by the plurality of float arms, and a cutterbar assembly carried by the plurality of float arms and movable in a localized manner in upwards and downwards directions.
摘要:
A method for electroless plating of metal on a laser-patterned substrate. A substrate is provided on which both a thermal imaging layer and catalytic layer are deposited. On exposure to a laser beam, sufficient levels of radiation are converted to heat in the thermal imaging layer to render the exposed regions of the adjacent catalytic layer inactive. The laser-patterned substrate is then exposed to a reaction solution which initiates the growth of a metal film on the unexposed regions of the catalytic layer.
摘要:
An implement, such as a header for a combine, having an integral transport system with a pair of ground engaging wheels that are moved between transport positions used in transporting the implement and stowed positions on the implement during use of the implement. The wheels may be used as gauge wheels during use to support the ends of the implement. A trailer tongue is retractable and stowed onboard the implement during use, as is a tongue jack. Lights are provided at the end of the implement for visibility during transport. The lights are stowed beneath a cover on the end of the implement to protect the lights from damage during use. All components of the transport system are carried on the implement during use to ensure that they are with the implement when needed to transport the implement. All components are mounted with pins, enabling the implement to be converted between transport and use configurations without the use of hand tools.