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公开(公告)号：US08318761B2
公开(公告)日：2012-11-27
申请号：US12203793
申请日：2008-09-03
Applicant: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
Inventor： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC: A01N43/40 , A61K31/435 , A61K31/44
CPC classification number: C07D413/04 , C07D213/73
Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
Abstract translation: 本发明涉及式（I）的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20110172207A1
公开(公告)日：2011-07-14
申请号：US12884113
申请日：2010-09-16
Applicant: Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
Inventor： Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
IPC: A61K31/4155 , C07D413/06 , C07D403/06 , C07D417/06 , A61K31/5377 , A61K31/553 , A61K31/427 , A61K31/5386 , A61K31/541 , A61K31/496 , A61P31/12 , A61P31/18
CPC classification number: C07D231/14 , A61K31/4155 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D451/06 , C07D491/08 , C07D498/08
Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
Abstract translation: 本发明涉及新型取代的吡唑啉酰胺，其制备方法，其用于治疗和/或预防疾病的用途，以及其用于制备用于治疗和/或预防疾病尤其是逆转录病毒疾病的药物的用途 ，在人类和/或动物中。
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公开(公告)号：US20090176842A1
公开(公告)日：2009-07-09
申请号：US12203793
申请日：2008-09-03
Applicant: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
Inventor： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC: A61K31/4439 , C07D413/04 , C07D213/73 , A61P31/12
CPC classification number: C07D413/04 , C07D213/73
Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
Abstract translation: 本发明涉及式（I）的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20070293478A1
公开(公告)日：2007-12-20
申请号：US11655589
申请日：2007-01-19
Applicant: Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
Inventor： Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
IPC: A61K31/497 , A61K31/5377 , A61K31/5513 , A61P31/22 , C07D243/08 , C07D401/02 , C07D413/14
CPC classification number: C07D215/56 , C07D401/04
Abstract: The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
Abstract translation: 本发明涉及取代的喹诺酮及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20070099929A1
公开(公告)日：2007-05-03
申请号：US11455253
申请日：2006-06-16
Applicant: Kai Thede , Tobias Wunberg , Timothy Lowinger , Diana Koletzki , Andreas Urban , Judith Baumeister , Kerstin Henninger
Inventor： Kai Thede , Tobias Wunberg , Timothy Lowinger , Diana Koletzki , Andreas Urban , Judith Baumeister , Kerstin Henninger
IPC: A61K31/496 , A61K31/453 , A61K31/4436 , A61K31/4025 , A61K31/381 , C07D409/02
CPC classification number: C07D409/04 , C07D333/38 , C07D409/12 , C07D409/14 , C07D417/04
Abstract: The invention relates to substituted thiophenes and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular for hepatitis C viruses.
Abstract translation: 本发明涉及取代的噻吩及其制备方法，其用于治疗和/或预防疾病的用途及其用于生产用于治疗和/或预防疾病，特别是用作抗病毒剂的药物的用途 特别适用于丙型肝炎病毒。
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Patent Agency Ranking
公开(公告)号：US07196086B2
公开(公告)日：2007-03-27
申请号：US10832109
申请日：2004-04-26
Applicant: Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jürgen Reefschläger , Rudolf Schohe-Loop , Frank Süssmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jörg Keldenich , Dieter Lang , Peter Nell
Inventor： Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jürgen Reefschläger , Rudolf Schohe-Loop , Frank Süssmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jörg Keldenich , Dieter Lang , Peter Nell
IPC: A61K31/517 , C07D43/04
CPC classification number: C07D239/84
Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
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47.发明申请2-(3-Phenyl-2-piperazinyl-3,4-dihydroquinazolin-4-yl)acetic acids as antiviral agents, especially against cytomegaloviruses 有权2-（3-苯基-2-哌嗪基-3,4-二氢喹唑啉-4-基）乙酸作为抗病毒剂，特别是针对巨细胞病毒公开(公告)号：US20070066622A1
公开(公告)日：2007-03-22
申请号：US10545453
申请日：2004-01-29
Applicant: Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefshlager , Rudolf Schohe-Loop , Frank Submeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Thomas Kramer , Peter Nell , Tse-I Lin
Inventor： Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefshlager , Rudolf Schohe-Loop , Frank Submeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Thomas Kramer , Peter Nell , Tse-I Lin
IPC: A61K31/517 , C07D405/14 , C07D403/02
CPC classification number: C07D239/84
Abstract: The invention relates to dihydroquinazolines and methods for the production thereof, the use thereof in the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments in the treatment and/or prophylaxis of diseases, especially for use as anti-viral agents, especially against cytomegalo viruses.
Abstract translation: 本发明涉及二氢喹唑啉及其制备方法，其用于治疗和/或预防疾病的用途，除了在制备药物中用于治疗和/或预防疾病，特别是用作 抗病毒剂，特别是针对巨细胞病毒。
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48.发明申请Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same 审中-公开取代的2-硫代-3,5-二氰基-4-苯基-6-氨基吡啶并使用它们公开(公告)号：US20060217373A1
公开(公告)日：2006-09-28
申请号：US11443693
申请日：2006-05-30
Applicant: Ulrich Rosentreter , Thomas Kramer , Mitsuyuki Shimada , Walter Hubsch , Nicole Diedrichs , Thomas Krahn , Kerstin Henninger , Johannes-Peter Stasch , Ralf Wischnat
Inventor： Ulrich Rosentreter , Thomas Kramer , Mitsuyuki Shimada , Walter Hubsch , Nicole Diedrichs , Thomas Krahn , Kerstin Henninger , Johannes-Peter Stasch , Ralf Wischnat
IPC: A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/497 , A61K31/4439 , A61K31/44
CPC classification number: C07D417/12 , C07D213/85 , C07D417/14
Abstract: Compounds of the formula (I) a process for their preparation and their use as medicaments are described.
Abstract translation: 描述了式（I）化合物的制备方法及其作为药物的用途。
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公开(公告)号：US20050107288A1
公开(公告)日：2005-05-19
申请号：US10490192
申请日：2002-09-06
Applicant: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
Inventor： Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
Abstract translation: 本发明涉及通式（I）的化合物，其制备方法，包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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公开(公告)号：US20050065160A1
公开(公告)日：2005-03-24
申请号：US10832109
申请日：2004-04-26
Applicant: Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Rudolf Schohe-Loop , Frank Sussmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Dieter Lang , Peter Nell
Inventor： Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Rudolf Schohe-Loop , Frank Sussmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Dieter Lang , Peter Nell
IPC: A61P31/22 , C07D239/84 , A61K31/517 , C07D43/04
CPC classification number: C07D239/84
Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
Abstract translation: 本发明涉及取代的二氢喹唑啉及其制备方法，也涉及其用于制备用于治疗和/或预防疾病，特别是用作抗病毒剂，特别是针对巨细胞病毒的药物的用途。
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