公开(公告)号：US09180236B2

公开(公告)日：2015-11-10

申请号：US13872984

申请日：2013-04-29

Applicant: ZOLL Circulation, Inc.

Inventor： Michael W. Dae ,  Timothy R. Machold

IPC: A61F7/00 ,  A61M1/10 ,  A61F7/12 ,  A61F7/10 ,  A61M19/00

CPC classification number: A61M1/1086 ,  A61F7/10 ,  A61F7/123 ,  A61F2007/0056 ,  A61F2007/0095 ,  A61F2007/126 ,  A61M1/106 ,  A61M1/107 ,  A61M1/1072 ,  A61M1/1074 ,  A61M1/125 ,  A61M19/00 ,  A61M2205/3606 ,  A61M2230/04

Abstract: Devices, systems and methods for treating disorders characterized by low cardiac output. The devices, systems and methods use intra-aortic balloon counterpulsation in combination with hypothermia of all or a portion of a human or veterinary patient's body to improve coronary perfusion and cardiac output. To effect the hypothermia, a heat exchange catheter may be positioned in the a patient's vasculature separately from the intra-aortic balloon counterpulsation catheter. Alternatively, a combination Intra-aortic balloon counterpulsation/heat exchange catheter may be utilized. Such combination catheter comprises a) a catheter sized for insertion into the aorta, b) a counterpulsation balloon and c) a heat exchanger. A drive/control system receives temperature and electrocardiograph signals and drives the inflation/deflation of the counterpulsation balloon as well as the heating/cooling of the heat exchanger.

Abstract translation: 用于治疗以低心输出量为特征的疾病的装置，系统和方法。 装置，系统和方法使用主动脉内气囊反搏与人或兽医患者身体的全部或一部分的低体温结合以改善冠状动脉灌注和心输出量。 为了降低体温，可以将热交换导管与主动脉内气囊反搏导管分开设置在患者的脉管系统中。 或者，可以使用主动脉内球囊反搏/热交换导管的组合。 这种组合导管包括a）尺寸适于插入主动脉的导管，b）反力气囊和c）热交换器。 驱动/控制系统接收温度和心电图仪信号并驱动反力气囊的充气/放气以及热交换器的加热/冷却。

公开(公告)号：US20150272777A1

公开(公告)日：2015-10-01

申请号：US14739906

申请日：2015-06-15

Applicant: ZOLL Circulation Inc.

Inventor： Robert Ginsburg ,  Timothy R. Machold ,  Michael T. Dineen

IPC: A61F7/12 ,  A61F7/00

CPC classification number: A61F7/12 ,  A61B18/00 ,  A61B18/082 ,  A61B18/245 ,  A61B2017/00084 ,  A61B2017/22051 ,  A61B2018/00095 ,  A61F7/007 ,  A61F7/0097 ,  A61F7/10 ,  A61F7/123 ,  A61F2007/0054 ,  A61F2007/0056 ,  A61F2007/0086 ,  A61F2007/0093 ,  A61F2007/0095 ,  A61F2007/0096 ,  A61F2007/126 ,  A61M25/00 ,  A61M25/1011 ,  A61M2025/0078 ,  A61M2025/1072 ,  A61M2025/1086 ,  A61M2205/366 ,  A61M2206/10 ,  A61M2230/50

Abstract: Devices and methods for controlling the operation of endovascular heat exchange devices and/or body surface heat exchange devices such as blankets.

Abstract translation: 用于控制血管内热交换装置和/或身体表面热交换装置如毛毯的操作的装置和方法。

公开(公告)号：US20150257926A1

公开(公告)日：2015-09-17

申请号：US14571044

申请日：2014-12-15

Applicant: ZOLL Circulation, Inc.

Inventor： Ben F. Brian, III ,  Scott D. Wilson

IPC: A61F7/12 ,  A61M25/10

CPC classification number: A61F7/12 ,  A61F2007/0056 ,  A61F2007/126 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/1072 ,  A61M2205/36 ,  A61M2205/3606 ,  A61M2205/366

Abstract: Devices and methods for warming or cooling blood flowing through the vasculature of a human or animal subject so as to alter or control the temperature of all or part of the subject's body. Heat exchangers are positioned within the subject's vasculature and heated or cooled heat exchange fluid is circulated through the heat exchanger. For certain therapeutic applications, the heat exchanger and associated elements of the system have sufficient power to lower the subject's body temperature by at least 3 degrees C. in less than 30 minutes.

Abstract translation: 用于升温或冷却血液流过人或动物受试者的脉管系统以改变或控制受试者身体全部或部分的温度的装置和方法。 热交换器位于受试者的脉管系统内，并且加热或冷却的热交换流体循环通过热交换器。 对于某些治疗应用，该系统的热交换器和相关元件具有足够的功率，可在不到30分钟内将受试者的体温降低至少3摄氏度。

公开(公告)号：US20150230975A1

公开(公告)日：2015-08-20

申请号：US14180719

申请日：2014-02-14

Applicant: Zoll Circulation, Inc.

Inventor： JEREMY THOMAS DABROWIAK ,  Craig Wendell Pendry ,  Christoph Matthias Pistor

IPC: A61F7/00 ,  A61F7/12

Abstract: A heat exchange system for exchanging heat with working fluid from an intravascular heat exchange catheter or an external heat exchange pad includes a working fluid that circulates between the catheter or pad and a fluid cassette, and a refrigerant system that flows against the outer sides of cold plates between which the cassette is disposed.

Abstract translation: 用于与来自血管内热交换导管或外部热交换垫的工作流体进行热交换的热交换系统包括在导管或垫与流体盒之间循环的工作流体，以及流过冷的外侧的制冷剂系统 在其间设置盒的板。

公开(公告)号：US20150182377A1

公开(公告)日：2015-07-02

申请号：US14656915

申请日：2015-03-13

Applicant: ZOLL CIRCULATION, INC.

Inventor： Jeremy T. Dabrowiak ,  Alex L. Lim ,  Venkata Vishnu Gurukula ,  Richard A. Helkowski ,  Masoumeh Mafi

IPC: A61F7/12

CPC classification number: A61F7/12 ,  A61F2007/0054 ,  A61F2007/126

Abstract: A catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. Plural wires arranged in a mesh are located longitudinally along the catheter and engaged therewith. The mesh can be moved between a radially expanded configuration, in which the mesh circumscribes an inner wall of a vessel in which the catheter is disposed and in which blood flowing through the vessel is not significantly impeded from flowing within the mesh past the catheter, and a radially collapsed configuration, in which the mesh lies against the catheter or is closely spaced therefrom to facilitate advancement and retraction of the catheter from the vessel.

Abstract translation: 导管包括工作流体供应和返回内腔，工作流体通过该内腔循环以与导管所位于的患者交换热量。 布置在网中的多根线沿着导管纵向定位并与其接合。 网状物可以在径向扩张的构型之间移动，其中网状物围绕其中布置导管的血管的内壁，并且流过血管的血液没有被显着阻止在网内超过导管的流动;以及 径向折叠的构造，其中网格抵靠导管或与其紧密地间隔开，以促进导管从血管的前进和缩回。

公开(公告)号：US20140324110A1

公开(公告)日：2014-10-30

申请号：US14307137

申请日：2014-06-17

Applicant: ZOLL Circulation Inc.

Inventor： Steven R. Bystrom ,  Darren R. Sherman

IPC: A61N1/39

CPC classification number: A61N1/3987 ,  A61H31/005 ,  A61H31/006 ,  A61H31/008 ,  A61H2031/003 ,  A61H2201/5007 ,  A61H2201/501 ,  A61H2201/5041 ,  A61H2201/5097 ,  A61H2230/04 ,  A61H2230/06 ,  A61H2230/42 ,  A61H2230/50 ,  A61N1/046 ,  A61N1/0472 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/39 ,  A61N1/3931 ,  A61N1/3993 ,  G06F21/34 ,  Y10S601/08

Abstract: A system for resuscitation of a heart attack victim. The system includes CPR device which compresses the victim's chest, a defibrillator which may be used to defibrillate the patient, and an identification system for identifying the person operating the system. Depending on the identity of the operator, the system permits varying degrees of access to components and enablement of the functions of the various subsystems.

Abstract translation: 复苏心脏病发作受害者的系统。 该系统包括压缩受害者胸部的CPR装置，可用于除颤患者的除颤器，以及用于识别操作系统的人的识别系统。 根据操作员的身份，系统允许对组件的访问程度不同，并且能够实现各种子系统的功能。

公开(公告)号：US20140288468A1

公开(公告)日：2014-09-25

申请号：US14294995

申请日：2014-06-03

Applicant: ZOLL CIRCULATION, INC.

Inventor： Reynaldo J. Quintana ,  Paul Q. Escudero ,  Charles E. Swinehart

IPC: A61H31/00

CPC classification number: A61H31/00 ,  A61H31/005 ,  A61H31/006 ,  A61H31/008 ,  A61H2201/5007 ,  A61H2201/5048 ,  Y10S601/06

Abstract: Devices and methods for attaching a belt cartridge to a belt drive platform. A clip attached to the belt is inserted into a slot in the drive spool of the belt drive platform. The cover plate of the belt cartridge fits into a channel beam in the housing of the belt drive platform, thereby securing the cartridge to the housing. Belt guards, for protecting the cartridge, belt drive platform, patient and rescuer, are rotatably attached to the cover plate and are secured around spindles disposed on the sides of the housing.

Abstract translation: 用于将带盒附接到皮带驱动平台的装置和方法。 附接到皮带的夹子插入皮带驱动平台的驱动卷轴中的槽中。 带盒的盖板装配在带驱动平台的壳体中的通道梁中，从而将盒固定到壳体。 用于保护盒，皮带驱动平台，患者和救生器的皮带护罩可旋转地附接到盖板并且被固定在设置在壳体的侧面上的主轴周围。

公开(公告)号：US20140172050A1

公开(公告)日：2014-06-19

申请号：US13715701

申请日：2012-12-14

Applicant: ZOLL CIRCULATION, INC.

Inventor： Jeremy Dabrowiak

IPC: A61F7/12

CPC classification number: A61F7/12 ,  A61F7/007 ,  A61F7/0085 ,  A61F2007/0076 ,  A61F2007/0095 ,  A61F2007/0295 ,  A61F2007/126

Abstract: A system and method for adding or removing heat from a heat exchange fluid circulating between an external heat exchanger and an intravascular heat exchange catheter is described. The system includes a two stage cooling system providing for a high rate of cooling in one stage and a lower rate of cooling in a second stage. Both stages may be used to provide maximal cooling while the second stage is used to provide improved control of the cooling rate as a target temperature is approached. The second stage may also be used to provide heat to the heat exchange fluid.

Abstract translation: 描述了一种用于从在外部热交换器和血管内热交换导管之间循环的热交换流体添加或除去热量的系统和方法。 该系统包括两级冷却系统，其在一个阶段提供高的冷却速率，在第二阶段提供较低的冷却速度。 可以使用两个阶段来提供最大的冷却，而第二阶段用于在接近目标温度时提供对冷却速度的改进的控制。 第二阶段也可用于向热交换流体提供热量。

公开(公告)号：US20140094883A1

公开(公告)日：2014-04-03

申请号：US13675241

申请日：2012-11-13

Applicant: ZOLL CIRCULATION, INC.

Inventor： Alex L. Lim ,  MASOUNEH MAFI ,  Venkata Vishnu Gurukula ,  Richard A. Helkowski

IPC: A61F7/12

CPC classification number: A61F7/12 ,  A61F2007/126

Abstract: An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated.

Abstract translation: 血管内热交换导管具有蛇形状供应和返回导管，循环工作流体与热交换系统以加热或冷却导管被插管的患者。

公开(公告)号：US20140067027A1

公开(公告)日：2014-03-06

申请号：US14071248

申请日：2013-11-04

Applicant: Zoll Circulation, Inc.

Inventor： Wayne Noda ,  Stelica Stelea

IPC: A61F7/12 ,  A61F7/00

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

Abstract translation: 用于留置热交换导管的冷却系统包括热交换浴，其被配置为接收将导管和/或从该导管携带的导管。 加热/冷却液在浴中，与盐水交换热量。 加热/冷却流体流过包括制冷剂的热交换器和用于从制冷剂中除去热量的两个变速直流压缩机。 齿轮泵将工作流体循环到导管和从导管流出并且可移除地与泵支撑平台接合。