公开(公告)号：US10603020B2

公开(公告)日：2020-03-31

申请号：US15358753

申请日：2016-11-22

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Barry Rudman ,  Jan Weber ,  Torsten Scheuermann ,  Stephen Ruble

IPC: A61B17/00 ,  A61F2/24 ,  A61M29/02 ,  A61F2/01 ,  A61B17/12

Abstract: A medical device for reducing the volume of a left atrial appendage (LAA) may include an elongate shaft having a distal portion, and a volume-reducing means expandable from a collapsed to an expanded state, the volume-reducing means being releasably attached to the distal portion. The volume-reducing means may include an actuatable frame and an impermeable covering disposed over the frame. The volume-reducing means may be sized to fit within the LAA in the expanded state while maintaining an open fluid flow path from a distal region through the ostium of the LAA. A medical device may include a second volume-reducing means to be placed within and substantially occlude a distalmost region of the LAA. A method may include inserting a volume-reducing means into the LAA, expanding the volume-reducing means, and positioning the volume-reducing means such that an open fluid flow path is maintained through an entire cycle of the heart.

公开(公告)号：US20200068876A1

公开(公告)日：2020-03-05

申请号：US16551998

申请日：2019-08-27

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  Megan Chrobak ,  Carolina Villarreal

IPC: A01N1/02

Abstract: Embodiments herein relate to systems and methods for thawing cells using magnetic particles, such as Curie-magnetic or Néel-magnetic particles. In an embodiment, a cell storage medium for cryopreservation is included. The cell storage medium can include a cryoprotective agent; and a plurality of particles comprising a magnetic material. In an embodiment, a method for thawing a frozen cell sample is included. The method can include obtaining a frozen cell sample comprising particles, the particles comprising a magnetic material and applying an alternating electromagnetic field to the frozen cell sample to induce heating of the magnetic material. Other embodiments are also included herein.

公开(公告)号：US10426920B2

公开(公告)日：2019-10-01

申请号：US14575675

申请日：2014-12-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Derek C. Sutermeister ,  James M. Anderson ,  Timothy A. Ostroot ,  Cass A. Hanson ,  Anthony F. Tassoni, Jr. ,  Timothy L. Rubesch ,  Jan Weber

IPC: A61M25/00 ,  A61M25/01

Abstract: A guide catheter may include a tubular member having an inner layer defining a lumen extending therethrough, a reinforcing braid disposed about the inner layer, a plurality of steering wires interwoven through the reinforcing braid, and an outer layer disposed about the reinforcing braid. At least a portion of the reinforcing braid may be embedded within the outer layer. An introducer sleeve may be slidably disposed over the tubular member. A flush port element may be operably connected to the introducer sleeve.

公开(公告)号：US20190091024A1

公开(公告)日：2019-03-28

申请号：US16139760

申请日：2018-09-24

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Jan Weber ,  Patricia McAfee ,  Tim O'Connor ,  Aiden Flanagan ,  Omar Jarral

IPC: A61F2/24

Abstract: Device sand methods for improving cardiac function are provided. The device includes a dome structure having a top end with an engagement element disposed thereon. The dome structure is moveable from a first inside out configuration to a second deployed configuration, and the dome structure is biased in the second deployed configuration. The dome structure includes a plurality of anchor members disposed around a bottom open end of the dome structure.

公开(公告)号：US20170333185A1

公开(公告)日：2017-11-23

申请号：US15595176

申请日：2017-05-15

Applicant: Boston Scientific Scimed Inc.

Inventor： Jan Weber ,  Haiying Zhou ,  Bruce R. Forsyth

IPC: A61F2/24 ,  C08K3/22 ,  B32B27/02

CPC classification number: A61F2/2415 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2210/0076 ,  A61F2250/0017 ,  A61F2250/0023 ,  A61F2250/0028 ,  A61F2250/0036 ,  A61F2250/0076 ,  A61L27/14 ,  A61L27/306 ,  B32B27/02 ,  C08K3/22 ,  C08K2003/2227 ,  C08K2003/2241 ,  C08K2003/2255 ,  D01F8/00 ,  D04H1/541 ,  D04H3/147

Abstract: Examples herein include prosthetic valves, valve leaflets and related methods. In an example, a prosthetic valve is included having a plurality of leaflets. The leaflets can each have a root portion and an edge portion substantially opposite the root portion and movable relative to the root portion. The leaflets can include a fibrous matrix including polymeric fibers having an average diameter of about 10 nanometers to about 10 micrometers. A coating can surround the polymeric fibers within the fibrous matrix. The coating can have a thickness of about 3 to about 30 nanometers. The coating can be formed of a material selected from the group consisting of a metal oxide, a nitride, a carbide, a sulfide, or fluoride. In an example, a method of making a valve is included. Other examples are also included herein.

公开(公告)号：US09420955B2

公开(公告)日：2016-08-23

申请号：US13647163

申请日：2012-10-08

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber

IPC: A61B5/01 ,  A61B5/02 ,  A61B18/14 ,  A61B5/00 ,  A61B18/00

CPC classification number: A61B5/01 ,  A61B5/02007 ,  A61B5/4836 ,  A61B5/6857 ,  A61B18/1492 ,  A61B2018/00196 ,  A61B2018/00214 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00702 ,  A61B2018/00797

Abstract: A system for monitoring one or more temperatures at a vessel wall of a vessel of a patient includes an optical fiber, an optical read-out mechanism, and a therapeutic device. The optical fiber may be deployed along an extent of the vessel and may include one or more fiber Bragg grating (FBG) temperature sensors disposed at one or more corresponding sensor locations along a length of the optical fiber. The optical read-out mechanism may be optically coupled to the optical fiber, and it may be configured to transmit light into the optical fiber and detect light reflected from the one or more FBG temperature sensors. The detected light reflected from the one or more FBG temperature sensors may encode local temperatures at each of the one or more corresponding sensor locations. The therapeutic device may be configured for performing a therapeutic procedure to or through the vessel wall.

Abstract translation: 用于监测患者血管壁的一个或多个温度的系统包括光纤，光学读出机构和治疗装置。 光纤可以沿着容器的一部分展开，并且可以包括沿着光纤的长度设置在一个或多个对应的传感器位置处的一个或多个光纤布拉格光栅（FBG）温度传感器。 光学读出机构可以光耦合到光纤，并且其可以被配置为将光透射到光纤中并且检测从一个或多个FBG温度传感器反射的光。 从一个或多个FBG温度传感器反射的检测光可以在一个或多个相应的传感器位置的每一个处编码局部温度。 治疗装置可以被配置用于对血管壁进行治疗或通过血管壁。

公开(公告)号：US09308078B2

公开(公告)日：2016-04-12

申请号：US14255586

申请日：2014-04-17

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  Aiden Flanagan ,  Torsten Scheuermann

IPC: A61F2/04

CPC classification number: A61F2/04 ,  A61F2002/043 ,  A61F2002/046

Abstract: A medical device for regulating fluid flow within one or more lungs of a patient is disclosed. The medical device includes an elongate tubular member, a first extension, a second extension, and a valve member. The elongate tubular member includes a first plurality of channels extending between a proximal and distal ends. The first and second extensions defines a second and third plurality of channels, respectively, each extending from the distal end of the elongate tubular member and configured for placement in a first and second passageway of a lung. The valve member operably couples to the elongate tubular member and is configured to transition between a first position and a second position. The valve member prevents fluid flow to first set of the first plurality of channels in the first position and prevents fluid flow to second set of the first plurality of channels in the second position.

Abstract translation: 公开了一种用于调节患者的一个或多个肺内的流体流动的医疗装置。 医疗装置包括细长管状构件，第一延伸部，第二延伸部和阀构件。 细长管状构件包括在近端和远端之间延伸的第一多个通道。 第一和第二延伸部分别限定第二和第三多个通道，每个通道从细长管状构件的远端延伸并且构造成用于放置在肺的第一和第二通道中。 阀构件可操作地连接到细长管状构件并且构造成在第一位置和第二位置之间转变。 阀构件防止流体在第一位置中首先设置第一多个通道，并防止在第二位置中流体流向第一组多个通道的第二组。

公开(公告)号：US20160089128A1

公开(公告)日：2016-03-31

申请号：US14965162

申请日：2015-12-10

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Jan Weber ,  Aiden Flanagan

IPC: A61B17/00 ,  A61M25/00

CPC classification number: A61B17/00234 ,  A61B17/3431 ,  A61B2017/00336 ,  A61B2017/00783 ,  A61B2090/08021 ,  A61L29/14 ,  A61M25/0023 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0054 ,  A61M2025/0047 ,  A61M2025/0063

Abstract: A medical device assembly may include an elongated guidewire, an elongated flexible tubular membrane disposed about the guidewire, and a percutaneous medical device, wherein the membrane is configured to permit the percutaneous medical device to pass through the lumen. A method of advancing a medical device through a vessel may include advancing an elongated flexible tubular membrane through the vessel to a treatment site, inserting the medical device into the membrane, and advancing the medical device through the membrane while maintaining the membrane in an axially stationary position relative to the vessel.

公开(公告)号：US20150342718A1

公开(公告)日：2015-12-03

申请号：US14824385

申请日：2015-08-12

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Jan Weber ,  James M. Anderson

IPC: A61F2/01 ,  A61F2/958 ,  A61M25/00

CPC classification number: A61F2/958 ,  A61F2/013 ,  A61F2/2433 ,  A61F2230/0006 ,  A61F2230/001 ,  A61F2230/005 ,  A61M25/0067 ,  A61M25/0074 ,  F04C2270/041

Abstract: A medical device may include an elongate shaft having a distal end portion and a balloon disposed at least partially within the distal end portion. The distal end portion may be configured to selectively expand from a collapsed delivery configuration to a distally-opening expanded filtering configuration. A method of deploying a medical device may include obtaining an elongate shaft having a distal end portion and a balloon disposed at least partially within the distal end portion, advancing the elongate shaft through a vessel to a treatment site, disposing at least a portion of the balloon within the treatment site with the distal end of the elongate shaft positioned adjacent the treatment site, at least partially inflating the balloon, thereby expanding the distal end portion, and deflating the balloon and subsequently performing a procedure with the distal end of the elongate shaft positioned within the vessel adjacent to the treatment site.

Abstract translation: 医疗装置可以包括具有至少部分地设置在远端部分内的远端部分和气囊的细长轴。 远端部分可以被构造成选择性地从折叠的输送构型扩展到远端开放的扩张过滤构型。 部署医疗装置的方法可以包括获得细长轴，其具有至少部分地设置在远端部分内的远端部分和气囊，并且将细长轴通过血管推进到治疗部位，将至少一部分 在处理部位内气囊，其中细长轴的远端定位成邻近治疗部位，至少部分地使气囊膨胀，从而使远端部分膨胀，并且使气囊放气并随后执行与细长轴的远端的过程 位于与处理部位相邻的容器内。

公开(公告)号：US09186486B2

公开(公告)日：2015-11-17

申请号：US13721847

申请日：2012-12-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  John M. Hokanson ,  John J. Chen

IPC: A61B18/14 ,  A61M25/10 ,  A61L29/12 ,  B82Y30/00 ,  A61F7/12 ,  B82Y5/00

CPC classification number: A61M25/104 ,  A61F7/123 ,  A61L29/126 ,  A61M25/10 ,  B82Y5/00 ,  B82Y30/00

Abstract: Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C.

Abstract translation: 公开了包括具有纳米管的气球的医疗系统和方法。 在一些实施例中，医疗系统包括细长轴和由轴承载并包括纳米管的可膨胀气囊。 医疗系统能够将球囊冷却到小于约37℃。在一些实施例中，一种方法包括提供具有细长轴的医疗装置和由细长轴承载并包括纳米管的可膨胀气囊; 并将气球冷却至小于约37℃。