公开(公告)号：USD841813S1

公开(公告)日：2019-02-26

申请号：US29635661

申请日：2018-02-01

Applicant: CARDIOVALVE LTD.

Designer： Ilia Hariton ,  Boaz Harari ,  Meni Iamberger ,  Aviram Baum

公开(公告)号：US11980547B2

公开(公告)日：2024-05-14

申请号：US18135436

申请日：2023-04-17

Applicant: CARDIOVALVE LTD.

Inventor： Boaz Harari ,  Ilia Hariton

IPC: A61F2/24 ,  A61F2/76 ,  G01B11/02 ,  G01B11/14 ,  G01L1/24 ,  G01N3/04 ,  H04N7/18

CPC classification number: A61F2/2472 ,  G01L1/24 ,  G01N3/04 ,  A61F2002/7635 ,  G01B11/02 ,  G01B11/14 ,  H04N7/18

Abstract: A method for testing a prosthetic heart valve leaflet is provided. The method includes using a vertical post having a longitudinal axis and a horizontal bar having a bar-axis that lies on a vertical bar-plane. The bar supports the leaflet along the bar-axis such that the leaflet drapes over the bar. A linear actuator movably couples the bar to the post, and actuation of the actuator moves the bar vertically in the bar-plane. A light source emits a beam of light and is oriented to direct the beam through the bar-plane. A gauge measures an elevation of the bar above the beam. A detector is positioned to detect the beam and generates a detection-signal indicative of detection of the beam. Other applications are also described.

公开(公告)号：US20230346549A1

公开(公告)日：2023-11-02

申请号：US18216391

申请日：2023-06-29

Applicant: Cardiovalve Ltd.

Inventor： Ilia HARITON ,  Meni Iamberger ,  Boaz Harari ,  Aviram Baum

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2220/0075 ,  A61F2/2427 ,  A61F2250/0003 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2/2436 ,  A61F2250/0039

Abstract: A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Each of the four sides of each of the four-sided closed cells is double-strutted. Other embodiments are also described.

公开(公告)号：US11337803B2

公开(公告)日：2022-05-24

申请号：US16135505

申请日：2018-09-19

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

IPC: A61F2/24

Abstract: A prosthetic heart valve, which may include an expandable annular outer frame having a tubular portion and at least one tissue anchor portion configured to extend from the tubular portion, may be provided. The at least one tissue anchor portion may have a plurality of attachment locations. The prosthetic heart valve may also include an expandable inner frame configured at least partially within the expandable annular outer frame. The expandable inner frame may be connected to the expandable annular outer frame solely at one or more of the plurality of attachment locations of the at least one tissue anchor portion.

公开(公告)号：US11337802B2

公开(公告)日：2022-05-24

申请号：US16135447

申请日：2018-09-19

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

IPC: A61F2/24

Abstract: A heart valve delivery system may be provided. The heart valve delivery system may include at least a first catheter movable relative to second and third catheters, arranged in a telescoping configuration. The second catheter may be movable relative to and extend from the distal end of the third catheter. The delivery system may include a first adjustable flexure radius associated with the second catheter, and a second flexure radius. The delivery system may include at one control handle assembly configured to permit the catheters to rotate together, independently adjust the first and second flexure radii, cause relative axial movement between the catheters, and permit the ejector to cause relative movement between a heart valve and a capsule connected to the first catheter.

公开(公告)号：US10918481B2

公开(公告)日：2021-02-16

申请号：US15668659

申请日：2017-08-03

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Boaz Harari ,  Maxim Karalnik ,  Meni Iamberger

IPC: A61F2/24 ,  A61F2/95 ,  A61F2/915

Abstract: A delivery tool includes a delivery capsule, disposed at a distal portion of the tool. The delivery capsule includes a proximal capsule-portion dimensioned to house a first part of an implant, and a distal capsule-portion dimensioned to house a second part of the implant; and an extracorporeal control portion, disposed at a proximal portion of the tool, the control portion including one or more controllers and one or more locks. The controllers are operatively coupled to the proximal and distal capsule-portions such that the proximal and distal capsule-portions are movable with respect to the implant via actuation of the controllers. The tool has sequential states in which movement of the proximal and distal capsule-portions is variously inhibited or facilitated.

公开(公告)号：US10905549B2

公开(公告)日：2021-02-02

申请号：US16136123

申请日：2018-09-19

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

IPC: A61F2/24

Abstract: A prosthetic valve for implantation within a native heart valve may be provided. The prosthetic valve may include an annular outer frame having a plurality of ventricular anchoring legs extending therefrom, as well as an inner frame having a plurality of atrial anchoring arms extending therefrom. A portion of each ventricular anchoring leg may be configured to overlap with a portion of each atrial anchoring arm in a common lateral plane. As a result, a prosthetic valve with a reduced axial length may be provided.

公开(公告)号：US10856975B2

公开(公告)日：2020-12-08

申请号：US16324339

申请日：2017-08-08

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Boaz Harari ,  Meni Iamberger ,  Aviram Baum

IPC: A61F2/24 ,  B23P15/00

Abstract: Apparatus is provided for use with a heart of a subject, the apparatus including an inner stent frame defining a tubular portion, and an outer stent frame. The apparatus has a relaxed expanded state in which an outer-stent-frame relaxed expanded diameter defined by the outer slept frame is smaller than an inner-stent-frame expanded diameter defined by the tubular portion. Together, the inner stent frame and the outer stent frame define a frame assembly in which outer-frame coupling elements are fixed to inner-frame coupling elements. The frame assembly is expandable into an expanded state in which the tubular portion defines an inner-stent-frame constrained expanded diameter that is smaller than the inner-stent-frame relaxed expanded diameter. The frame assembly includes prosthetic leaflets secured to, and disposed within, the tubular portion, and has a compressed state in which the frame assembly is transluminally advanceable to the heart. Other embodiments are also described.

公开(公告)号：US10667908B2

公开(公告)日：2020-06-02

申请号：US16041208

申请日：2018-07-20

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Boaz Harari

IPC: A61F2/24 ,  A61F2/915 ,  A61F2/95

Abstract: Embodiments of the present disclosure are directed to prosthetic valves and methods of use thereof. In one implementation, a prosthetic valve may include an annular valve body and a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. At least one ventricular anchoring leg may include a first concave portion situated between the valve body and a terminal end of the leg, and a second concave portion situated between the first concave portion and the terminal end of the leg. The first concave portion may face radially outward, while the second concave portion may face radially inward. At least one of the first concave portion and the second concave portion may be angularly aligned with a point of connection between the at least one leg and the valve body.

公开(公告)号：US20200038181A1

公开(公告)日：2020-02-06

申请号：US16591330

申请日：2019-10-02

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Boaz Harari

IPC: A61F2/24

Abstract: A valve frame is shaped to define a plurality of atrial arms, and a tubular portion that defines a lumen along a longitudinal axis of the valve frame. Prosthetic leaflets within the lumen are coupled to the frame. An outer frame defines a ring and a plurality of ventricular legs coupled to the ring. The ring circumscribes the tubular portion, and is defined by a pattern of alternating peaks and troughs. The tubular portion defines a row of upstream cells, and a row of downstream cells that is tessellated with the row of upstream cells. Each of the atrial arms is attached to, and extends from, a respective connection site at which adjacent upstream cells are connected to each other. Other embodiments are also described.