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    Prosthetic heart valve and delivery apparatus
    43.
    发明授权
    Prosthetic heart valve and delivery apparatus 有权

    公开(公告)号：US10238487B2

    公开(公告)日：2019-03-26

    申请号：US15181243

    申请日：2016-06-13

    Applicant: Edwards Lifesciences Corporation

    Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

    IPC: A61F2/24 ,  A61F2/95

    Abstract: Embodiments of the present disclosure provide a prosthetic heart valve and a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. A delivery apparatus for delivering s self-expanding prosthetic valve can be configured to allow controlled and precise deployment of the valve from a valve sheath so as to minimize or prevent jumping of the valve from the valve sheath.

    Replacement prosthetic heart valves
    44.
    发明授权
    Replacement prosthetic heart valves 有权

    公开(公告)号：US10226338B1

    公开(公告)日：2019-03-12

    申请号：US16197280

    申请日：2018-11-20

    Applicant: Edwards Lifesciences Corporation

    Inventor： Stanton J. Rowe ,  Larry L. Wood ,  Henry Bourang ,  George Bakis ,  Benjamin Spenser ,  Netanel Benichou ,  Assaf Bash ,  Yaron Keidar

    IPC: A61F2/24 ,  A61F2/90 ,  A61L27/36

    Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

    PROSTHETIC HEART VALVE AND DELIVERY APPARATUS
    48.
    发明申请
    PROSTHETIC HEART VALVE AND DELIVERY APPARATUS 审中-公开
    先天性心脏瓣膜和输送装置

    公开(公告)号：US20160287386A1

    公开(公告)日：2016-10-06

    申请号：US15181243

    申请日：2016-06-13

    Applicant: Edwards Lifesciences Corporation

    Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/0039

    Abstract: Embodiments of the present disclosure provide a prosthetic heart valve and a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. A delivery apparatus for delivering s self-expanding prosthetic valve can be configured to allow controlled and precise deployment of the valve from a valve sheath so as to minimize or prevent jumping of the valve from the valve sheath.

    Abstract translation: 本公开的实施例提供了一种假体心脏瓣膜和心脏瓣膜输送装置，用于经由人类脉管系统将假体心脏瓣膜输送到天然瓣膜部位。 输送装置特别适用于通过主动脉推进人工瓣膜（即逆行方法），以更换患病的天然主动脉瓣。 在一个实施例中，自膨胀阀包括可扩张支架，其被成形为在不具有接合周围组织的锚固件或保持装置的情况下将阀保持在主动脉环中以抵抗轴向。 用于输送自膨胀假体瓣膜的输送装置可以构造成允许阀从阀套被控制和精确地展开，以便最小化或防止阀从阀套跳跃。

    Prosthetic heart valve having improved commissure supports
    49.
    发明授权
    Prosthetic heart valve having improved commissure supports 有权
    具有改善的连合支撑的假心脏瓣膜

    公开(公告)号：US09168131B2

    公开(公告)日：2015-10-27

    申请号：US13708598

    申请日：2012-12-07

    Applicant: Edwards Lifesciences Corporation

    Inventor： Ziv Yohanan ,  Tamir S. Levi ,  Netanel Benichou ,  Michael Bukin ,  Nik Gurovich ,  Elena Sherman

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0039

    Abstract: A prosthetic heart valve according to the present disclosure comprises a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame in particular embodiments can have commissure attachment portions that are configured to support the commissures of the leaflets at locations spaced radially inwardly toward the longitudinal flow axis of the prosthetic valve relative to the frame portions circumscribing the moveable portions of the leaflets. When the leaflets open under pressure of blood flowing through the prosthetic valve, the moveable portions of the leaflets are retained at positions spaced inwardly from the inner surface of the frame to protect against abrasion of the leaflets.

    Abstract translation: 根据本公开的假体心脏瓣膜包括径向可折叠和可扩张的环形框架和包括安装在框架内的多个传单的小叶结构。 在特定实施例中的框架可以具有接合连接部分，其被构造成在相对于限定传单的可移动部分的框架部分的支撑下，支撑传播叶片在与假肢瓣膜的纵向流动轴线径向向内间隔的位置处的连接。 当小叶在血液流过人工瓣膜的压力下打开时，小叶的可移动部分被保持在与框架的内表面向内间隔开的位置处，以防止小叶的磨损。

    LEAFLET ATTACHMENT FRAME FOR PROSTHETIC VALVE
    50.
    发明公开
    LEAFLET ATTACHMENT FRAME FOR PROSTHETIC VALVE 审中-公开

    公开(公告)号：US20240225824A1

    公开(公告)日：2024-07-11

    申请号：US18433220

    申请日：2024-02-05

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Netanel Benichou

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2409 ,  A61F2210/0076 ,  A61F2220/0075 ,  A61F2230/0054

    Abstract: An implantable prosthetic valve includes a frame and a leaflet structure positioned within the frame. The frame has a plurality of angled struts arranged to form a plurality of circumferentially extending rows of closed cells, including an uppermost row of closed cells defining an outflow end of the frame. The leaflet structure includes a plurality of leaflets, each having two opposing commissure portions and a lower edge portion coupled to the frame. Each commissure portion is paired with an adjacent commissure portion of an adjacent leaflet to form a commissure of the leaflet structure. The frame has a plurality of commissure support portions supporting respective commissures. The commissure support portions are positioned axially along the frame entirely within the uppermost row of closed cells. The commissure support portions are circumferentially spaced apart from each other by a plurality of closed cells of the uppermost row of closed cells.

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