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120 条记录 (耗时 0.03 秒)

    Contact lenses
    41.
    发明授权
    Contact lenses 失效
    隐形眼镜

    公开(公告)号：US5106930A

    公开(公告)日：1992-04-21

    申请号：US383802

    申请日：1989-07-21

    申请人： Amitava Gupta

    发明人： Amitava Gupta

    IPC分类号： G02C7/04 ,  C08L27/12 ,  G02B1/04

    CPC分类号： G02B1/043

    摘要： A contact lens material which is lipophobic, easily machined and is oxygen permeable which comprises a copolymer comprising from 25% to 50% by weight of a polysiloxanylalkyl ester of acrylic or methacrylic acid, from 40% to 69% by weight of a fluorinated styrene, from 4% to 7% of a hydrophilic monomer, from 2% to 5% of a suitable cross-linking agent and from 0% to 2% of a UV absorber.

    Method of forming single-piece intraocular lens and core member and lens formed thereby
    42.
    发明授权
    Method of forming single-piece intraocular lens and core member and lens formed thereby 失效
    形成单片眼内透镜和由其形成的芯部件和透镜的方法

    公开(公告)号：US4813956A

    公开(公告)日：1989-03-21

    申请号：US34349

    申请日：1987-04-03

    申请人： Amitava Gupta

    发明人： Amitava Gupta

    IPC分类号： A61L27/00 ,  A61F2/16 ,  A61L27/16 ,  A61L27/50 ,  B29D11/02 ,  B29D11/00

    CPC分类号： B29D11/023 ,  A61F2/16 ,  A61L27/14 ,  A61L27/16 ,  A61L27/50 ,  A61L2430/16 ,  Y10S623/901

    摘要： A method of forming single-piece intraocular lenses comprising the steps of forming a thin sheet of colored polymethyl methacrylate, coring the sheet to form holes therein, filling the holes with a clear or differently colored PMMA material, polymerizing the colored and clear or differently colored PMMA material comprising the sheet and filled holes, cutting core members from the polymerized sheet each having an inner circular region of PMMA material and an outer region of colored PMMA material and machining a single-piece intraocular lens from a core member to have a central lens body of PMMA material and colored PMMA positioning loops extending from and integral with the central lens body.

    摘要翻译： 一种形成单件式眼内透镜的方法，包括以下步骤：形成着色的聚甲基丙烯酸甲酯薄片，使片材取芯，在其中形成孔，用透明或不同颜色的PMMA材料填充孔，聚合有色和透明或不同颜色的 包括片材和填充孔的PMMA材料，从聚合片材切割芯片，每个聚合片材均具有PMMA材料的内圆形区域和着色的PMMA材料的外部区域，并且从芯部件加工单件眼内透镜以具有中心透镜 PMMA材料的主体和从中心透镜主体延伸并与之成一体的彩色PMMA定位环。

    Hermetically sealed implantable ophthalmic devices and methods of making same
    43.
    发明授权
    Hermetically sealed implantable ophthalmic devices and methods of making same 有权
    密封可植入眼科装置及其制造方法

    公开(公告)号：US08992610B2

    公开(公告)日：2015-03-31

    申请号：US13812226

    申请日：2011-07-25

    申请人： Ronald D. Blum ,  Amitava Gupta ,  Jean-Noel Fehr ,  Jean-Christophe Roulet ,  Urban Schnell ,  Walter Doll ,  Roland Michaely

    发明人： Ronald D. Blum ,  Amitava Gupta ,  Jean-Noel Fehr ,  Jean-Christophe Roulet ,  Urban Schnell ,  Walter Doll ,  Roland Michaely

    IPC分类号： A61F2/16 ,  A61F2/14

    CPC分类号： A61F2/1624 ,  A61F2/14 ,  A61F2/1613 ,  A61F2002/482 ,  A61F2240/001 ,  A61F2250/0069 ,  G02F1/1341 ,  H01L23/15 ,  H01L23/5389 ,  H05K3/301 ,  H05K3/36 ,  Y10T29/49126

    摘要： Many modern implantable ophthalmic devices include electronic components, such as electro-active cells, that can leak harmful substances into the eye and/or surrounding tissue. In the implantable ophthalmic devices disclosed herein, electronic components are hermetically scaled within cavities formed by bonding together two or more glass wafers. Bonding the glass wafers together with laser fusion bonding, pressure bonding, or anodic bonding creates a seal that leaks at a rate of less than about 5×10−12 Pa m3 s−1 when subjected to a helium leak test. Hermetically sealed feedthroughs formed of conductive material running through channels in the wafers provide electrical connections to components inside the sealed cavities. In some cases, the conductive material has a coefficient of thermal expansion (CTE) that is roughly equal to (e.g., within 10% of) the CTE of the glass wafers to minimize leakage due to thermally induced expansion and contraction of the conductive material and the glass wafer.

    摘要翻译： 许多现代可植入眼科装置包括可将有害物质渗入眼睛和/或周围组织的电子部件，例如电活性细胞。 在本文公开的可植入眼科装置中，电子部件通过将两个或更多个玻璃晶片结合在一起形成的空腔内被气密地缩放。 通过激光熔接，压力粘合或阳极接合将玻璃晶片结合在一起形成密封，当进行氦气泄漏测试时，密封件以小于约5×10-12 Pa m3 s-1的速率泄漏。 由导电材料形成的密封馈通通过晶片中的通道提供电连接到密封空腔内的组件。 在一些情况下，导电材料的热膨胀系数（CTE）大致等于玻璃晶片的CTE的（例如，在10％以内），以最小化由于导致导电材料的热诱导的膨胀和收缩引起的泄漏， 玻璃晶片。

    Methods of filling a liquid-filled lens mechanism
    45.
    发明授权
    Methods of filling a liquid-filled lens mechanism 失效
    填充充满液体的透镜机构的方法

    公开(公告)号：US08567946B2

    公开(公告)日：2013-10-29

    申请号：US13341389

    申请日：2011-12-30

    申请人： Amitava Gupta ,  Karim Haroud ,  Urban Schnell

    发明人： Amitava Gupta ,  Karim Haroud ,  Urban Schnell

    IPC分类号： G02C7/02 ,  G02B3/12 ,  G02B3/14 ,  G02B1/06

    CPC分类号： G02C7/085 ,  G02B3/14

    摘要： Methods for filling an internal volume of a liquid filled lens mechanism with fluid are provided. In some embodiments, the methods include creating a vacuum within the internal volume, de-aerating the fluid, filling the vacuum in the internal volume with the de-aerated fluid, and sealing the internal volume. In some embodiments, the methods include elevating a temperature of the fluid prior to sealing the internal volume. In some embodiments, the internal volume is formed by a structure having at least one flexible component.

    摘要翻译： 提供了用流体填充液体填充的透镜机构的内部容积的方法。 在一些实施例中，所述方法包括在内部体积内产生真空，使流体脱气，用脱气流体填充内部体积的真空并密封内部体积。 在一些实施例中，所述方法包括在密封内部体积之前升高流体的温度。 在一些实施例中，内部体积由具有至少一个柔性部件的结构形成。

    METHOD AND APPARATUS FOR DETECTING ACCOMMODATION
    46.
    发明申请
    METHOD AND APPARATUS FOR DETECTING ACCOMMODATION 审中-公开
    检测住房的方法和装置

    公开(公告)号：US20130242256A1

    公开(公告)日：2013-09-19

    申请号：US13822569

    申请日：2011-09-12

    申请人： Jean-Noel Fehr ,  Urban Schnell ,  Walter Doll ,  Roland Michaely ,  Jean-Christophe Roulet ,  Amitava Gupta ,  Ronald Blum ,  Rudy Mazzocchi

    发明人： Jean-Noel Fehr ,  Urban Schnell ,  Walter Doll ,  Roland Michaely ,  Jean-Christophe Roulet ,  Amitava Gupta ,  Ronald Blum ,  Rudy Mazzocchi

    IPC分类号： A61B3/11

    CPC分类号： A61B3/11 ,  A61B3/09 ,  A61B3/112 ,  A61F2/1624 ,  A61F2250/0002 ,  G02C7/083

    摘要： A sensor system includes at least two sensors for distinguishing accommodative stimuli from changes in ambient lights levels and task-induced changes in the pupil diameter. When implanted, the first sensor is disposed completely within the pupil; even when fully constricted, the pupil does not occlude the first sensor, allowing the sensor to make precise measurements of ambient luminous flux levels. The pupil occludes part of the second sensor's active area(s) as the pupil dilates and constricts. As a result, the second sensor measures both ambient luminous flux and pupil diameter. A processor estimates the pupil diameter and determines whether it's changing in response to accommodative stimuli or other factors by comparing to predetermined values. The sensor system sends a signal to an optical component, which in turn can respond by changing optical power to focus for near vision upon detection of accommodative stimuli.

    摘要翻译： 传感器系统包括至少两个传感器，用于区分调节刺激与环境光照水平的变化以及瞳孔直径的任务引起的变化。 当植入时，第一传感器完全设置在瞳孔内; 即使完全收缩，瞳孔也不会闭塞第一个传感器，允许传感器对环境光通量水平进行精确测量。 当瞳孔扩大和收缩时，瞳孔封闭第二传感器的有效区域的一部分。 结果，第二传感器测量环境光通量和瞳孔直径。 处理器估计瞳孔直径并且通过与预定值进行比较来确定其是否响应于调节刺激或其他因素而改变。 传感器系统将信号发送到光学部件，光学部件又可以通过改变光焦度进行响应，以便在检测到适应刺激时进行近视。

    IMPLANTABLE OPHTHALMIC DEVICES WITH CIRCULARLY ASYMMETRIC OPTIC AND METHODS
    47.
    发明申请
    IMPLANTABLE OPHTHALMIC DEVICES WITH CIRCULARLY ASYMMETRIC OPTIC AND METHODS 审中-公开
    具有圆形非对称光学和方法的可植入眼科装置

    公开(公告)号：US20130211515A1

    公开(公告)日：2013-08-15

    申请号：US13805742

    申请日：2011-06-24

    申请人： Ronald D. Blum ,  Amitava Gupta ,  Julien Sauvet ,  Jean-Noel Fehr ,  Urban Schnell

    发明人： Ronald D. Blum ,  Amitava Gupta ,  Julien Sauvet ,  Jean-Noel Fehr ,  Urban Schnell

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1624 ,  A61F2/1637

    摘要： Astigmatism is an optical aberration that displaces the eye's vertical focal plane with respect to its horizontal focal plane. This displacement in focal planes, which may be caused by an irregularly shaped cornea and/or crystalline lens, causes images to appear blurry. Astigmatism can be corrected by implanting an optic, such as section of a spherical lens, whose projection onto a plane perpendicular to the optical axis is noncircular (e.g., rectangular or elliptical). Because the optic is noncircular, it provides more optical power along one axis than along another axis. As a result, it introduces an astigmatism that can be used to offset or compensate the eye's corneal and/or lenticular astigmatism when aligned properly with respect to the principal meridians of the cornea and/or crystalline lens.

    摘要翻译： 散光是相对于其水平焦平面移动眼睛的垂直焦平面的光学像差。 可能由不规则形状的角膜和/或晶状体引起的焦平面中的位移导致图像看起来模糊。 可以通过植入诸如球面透镜的部分的光学元件校正散光，其中投影在垂直于光轴的平面上是非圆形的（例如，矩形或椭圆形）。 因为光学元件是非圆形的，所以它沿着一个轴提供比另一个轴更多的光学功率。 结果，当相对于角膜和/或晶状体的主经脉正确对准时，其引入散光，其可用于抵消或补偿眼睛的角膜和/或透镜散光。

    Non-round fluid filled lens optic
    48.
    发明授权
    Non-round fluid filled lens optic 失效
    非圆形流体填充透镜光学元件

    公开(公告)号：US08414121B2

    公开(公告)日：2013-04-09

    申请号：US12848910

    申请日：2010-08-02

    申请人： Amitava Gupta ,  Urban Schnell ,  Karim Haroud ,  Hans Jaeger ,  Lisa Nibauer ,  Pascal Loser ,  William Egan

    发明人： Amitava Gupta ,  Urban Schnell ,  Karim Haroud ,  Hans Jaeger ,  Lisa Nibauer ,  Pascal Loser ,  William Egan

    IPC分类号： G02C7/02 ,  G02B3/12

    CPC分类号： G02B3/14 ,  G02C7/085

    摘要： An optical and mechanical design of a sealed, non-round fluid-filled lens capable of providing variation of optical power. The fluid lens includes at least three optical components: at least one mostly rigid optical disc, at least one mostly flexible optical membrane and a layer of a transparent fluid that is in communication via a fluid channel with a reservoir of excess fluid contained in a reservoir that can be accessed to augment the fluid volume inside the fluid lens to change the power of the fluid lens. The fluid lens is capable of providing correction of spherical and astigmatic errors, and utilizes contoured membranes to minimize image aberrations.

    摘要翻译： 密封的非圆形流体充满透镜的光学和机械设计，能够提供光功率的变化。 流体透镜包括至少三个光学部件：至少一个大致刚性的光盘，至少一个主要柔性的光学膜和透明流体层，该透明​​流体通过流体通道与容纳在储存器中的过量流体的储存器连通 可以访问以增加流体透镜内的流体体积以改变流体透镜的功率。 流体透镜能够提供球面和散光误差的校正，并且利用轮廓膜来最小化图像像差。

    Variable focus liquid filled lens apparatus
    50.
    发明授权
    Variable focus liquid filled lens apparatus 失效

    公开(公告)号：US08382280B2

    公开(公告)日：2013-02-26

    申请号：US12986589

    申请日：2011-01-07

    申请人： Amitava Gupta ,  Karim Haroud ,  Urban Schnell

    发明人： Amitava Gupta ,  Karim Haroud ,  Urban Schnell

    IPC分类号： G02C7/02

    CPC分类号： G02C7/085 ,  G02B1/11 ,  G02B1/14 ,  G02B3/02 ,  G02B3/14 ,  G02C2202/16

    摘要： A variable focus optical apparatus including a rigid, curved, transparent optical component; two transparent, distensible membranes attached to a periphery of the rigid optical component to define two cavities, a first cavity between the rigid optical component and a first membrane and a second cavity between the first membrane and a second membrane; and a variable amount of fluid filling each of the cavities, and a reservoir containing additional fluid and in fluid communication with the cavity, wherein the reservoir is configured to provide injection of fluid into the cavity or withdrawal of fluid out of the cavity in response to a force or an impulse.