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公开(公告)号:US20060128706A1
公开(公告)日:2006-06-15
申请号:US11127940
申请日:2005-05-12
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
IPC分类号: A61K31/53 , A61K31/506 , A61K31/501 , A61K31/4965 , A61K31/497 , A61K31/4439 , A61K31/4436 , A61K31/44 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号: C07D295/155 , C07D207/24 , C07D211/20 , C07D211/26 , C07D211/48 , C07D211/70 , C07D211/72 , C07D213/38 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/12 , C07D257/04 , C07D277/36 , C07D295/185 , C07D295/30 , C07D307/22 , C07D309/20 , C07D333/20 , C07D333/34 , C07D401/12 , C07D403/12 , C07D487/04
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
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公开(公告)号:US08614318B2
公开(公告)日:2013-12-24
申请号:US11491851
申请日:2006-07-24
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander R. Shoemaker , Michael J. Mitten
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander R. Shoemaker , Michael J. Mitten
IPC分类号: C07D211/06 , C07D413/02
CPC分类号: C07D233/06 , C07D205/04 , C07D207/06 , C07D207/08 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/20 , C07D207/24 , C07D207/50 , C07D211/14 , C07D211/20 , C07D211/26 , C07D211/34 , C07D211/38 , C07D211/42 , C07D211/46 , C07D211/48 , C07D211/58 , C07D211/62 , C07D211/70 , C07D211/72 , C07D213/36 , C07D213/38 , C07D213/42 , C07D213/70 , C07D213/74 , C07D213/81 , C07D213/82 , C07D215/12 , C07D231/12 , C07D231/56 , C07D233/61 , C07D233/64 , C07D235/08 , C07D239/06 , C07D239/38 , C07D241/04 , C07D249/18 , C07D257/04 , C07D261/20 , C07D263/12 , C07D263/22 , C07D263/58 , C07D265/30 , C07D267/10 , C07D273/01 , C07D277/36 , C07D277/74 , C07D295/155 , C07D295/185 , C07D295/30 , C07D307/14 , C07D307/22 , C07D307/81 , C07D309/14 , C07D309/20 , C07D317/66 , C07D333/20 , C07D333/34 , C07D335/02 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/10 , C07D413/04 , C07D471/08 , C07D487/04 , C07D487/08 , C07D491/04 , C07D491/08 , C07D498/08
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
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公开(公告)号:US20060258657A1
公开(公告)日:2006-11-16
申请号:US11202827
申请日:2005-08-12
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
IPC分类号: A61K31/53 , A61K31/506 , A61K31/497 , A61K31/501 , A61K31/4745 , C07D471/02
CPC分类号: C07D207/24 , C07D211/20 , C07D211/26 , C07D211/48 , C07D211/70 , C07D211/72 , C07D213/38 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/12 , C07D257/04 , C07D277/36 , C07D295/155 , C07D295/185 , C07D295/30 , C07D307/22 , C07D309/20 , C07D333/20 , C07D333/34 , C07D401/12 , C07D403/12 , C07D487/04
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
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公开(公告)号:US08173811B2
公开(公告)日:2012-05-08
申请号:US12800702
申请日:2010-05-19
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
IPC分类号: C07D235/02
CPC分类号: C07D295/155 , C07D207/24 , C07D211/20 , C07D211/26 , C07D211/48 , C07D211/70 , C07D211/72 , C07D213/38 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/12 , C07D257/04 , C07D277/36 , C07D295/185 , C07D295/30 , C07D307/22 , C07D309/20 , C07D333/20 , C07D333/34 , C07D401/12 , C07D403/12 , C07D487/04
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
摘要翻译: 公开了抑制抗凋亡蛋白家族成员的活性的化合物,含有化合物的组合物和该化合物用于制备用于治疗疾病的药物的用途,其中发生表达一种或多种抗凋亡蛋白家族成员。
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公开(公告)号:US20110256129A1
公开(公告)日:2011-10-20
申请号:US13093753
申请日:2011-04-25
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
IPC分类号: A61K31/635 , A61K39/395 , A61K31/7048 , A61P35/00 , A61K31/495 , A61K31/63 , A61K31/497 , A61K31/675 , A61K31/704
CPC分类号: C07D295/155 , C07C311/51 , C07D205/04 , C07D207/06 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/20 , C07D207/24 , C07D207/50 , C07D209/02 , C07D209/52 , C07D211/14 , C07D211/20 , C07D211/26 , C07D211/34 , C07D211/38 , C07D211/42 , C07D211/46 , C07D211/48 , C07D211/58 , C07D211/62 , C07D211/70 , C07D211/72 , C07D213/36 , C07D213/38 , C07D213/42 , C07D213/70 , C07D213/74 , C07D213/81 , C07D213/82 , C07D215/12 , C07D231/12 , C07D231/56 , C07D233/06 , C07D233/22 , C07D233/24 , C07D233/61 , C07D233/64 , C07D235/08 , C07D239/06 , C07D239/20 , C07D239/38 , C07D241/04 , C07D249/18 , C07D257/04 , C07D261/20 , C07D263/12 , C07D263/22 , C07D263/58 , C07D265/30 , C07D267/10 , C07D273/01 , C07D277/04 , C07D277/36 , C07D277/74 , C07D295/185 , C07D295/30 , C07D307/14 , C07D307/22 , C07D307/81 , C07D309/14 , C07D309/20 , C07D317/66 , C07D333/20 , C07D333/34 , C07D335/02 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/10 , C07D413/04 , C07D451/02 , C07D471/08 , C07D487/04 , C07D487/08 , C07D491/04 , C07D491/048 , C07D491/08 , C07D498/08
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
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公开(公告)号:US07973161B2
公开(公告)日:2011-07-05
申请号:US11600445
申请日:2006-11-16
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
IPC分类号: C07D241/02 , C07D403/02
CPC分类号: C07D295/155 , C07C311/51 , C07D205/04 , C07D207/06 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/20 , C07D207/24 , C07D207/50 , C07D209/02 , C07D209/52 , C07D211/14 , C07D211/20 , C07D211/26 , C07D211/34 , C07D211/38 , C07D211/42 , C07D211/46 , C07D211/48 , C07D211/58 , C07D211/62 , C07D211/70 , C07D211/72 , C07D213/36 , C07D213/38 , C07D213/42 , C07D213/70 , C07D213/74 , C07D213/81 , C07D213/82 , C07D215/12 , C07D231/12 , C07D231/56 , C07D233/06 , C07D233/22 , C07D233/24 , C07D233/61 , C07D233/64 , C07D235/08 , C07D239/06 , C07D239/20 , C07D239/38 , C07D241/04 , C07D249/18 , C07D257/04 , C07D261/20 , C07D263/12 , C07D263/22 , C07D263/58 , C07D265/30 , C07D267/10 , C07D273/01 , C07D277/04 , C07D277/36 , C07D277/74 , C07D295/185 , C07D295/30 , C07D307/14 , C07D307/22 , C07D307/81 , C07D309/14 , C07D309/20 , C07D317/66 , C07D333/20 , C07D333/34 , C07D335/02 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/10 , C07D413/04 , C07D451/02 , C07D471/08 , C07D487/04 , C07D487/08 , C07D491/04 , C07D491/048 , C07D491/08 , C07D498/08
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
摘要翻译: 公开了抑制抗凋亡蛋白家族成员的活性的化合物,含有化合物的组合物和化合物用于制备用于治疗疾病的药物的用途,其中发生表达一种或多种抗凋亡蛋白家族成员。
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公开(公告)号:US07767684B2
公开(公告)日:2010-08-03
申请号:US11127940
申请日:2005-05-12
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt
IPC分类号: A61K31/4965 , C07D241/04 , C07D295/00
CPC分类号: C07D295/155 , C07D207/24 , C07D211/20 , C07D211/26 , C07D211/48 , C07D211/70 , C07D211/72 , C07D213/38 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/12 , C07D257/04 , C07D277/36 , C07D295/185 , C07D295/30 , C07D307/22 , C07D309/20 , C07D333/20 , C07D333/34 , C07D401/12 , C07D403/12 , C07D487/04
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
摘要翻译: 公开了抑制抗凋亡蛋白家族成员的活性的化合物,含有该化合物的组合物和该化合物用于制备用于治疗疾病的药物的用途,其中发生表达一种或多种抗凋亡蛋白家族成员。
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公开(公告)号:US07642260B2
公开(公告)日:2010-01-05
申请号:US11202827
申请日:2005-08-12
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher L. Lynch , William McClellan , Cheol-Min Park , Andrew Petros , Xiaohong Song , Xilu Wang , Noah Tu , Michael Wendt , Alexander Shoemaker , Michael Mitten
IPC分类号: A61K31/496 , C07D241/04
CPC分类号: C07D207/24 , C07D211/20 , C07D211/26 , C07D211/48 , C07D211/70 , C07D211/72 , C07D213/38 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/12 , C07D257/04 , C07D277/36 , C07D295/155 , C07D295/185 , C07D295/30 , C07D307/22 , C07D309/20 , C07D333/20 , C07D333/34 , C07D401/12 , C07D403/12 , C07D487/04
摘要: Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
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公开(公告)号:US08577374B2
公开(公告)日:2013-11-05
申请号:US13379334
申请日:2010-06-08
申请人: Xiaojiang Han , Hong Ding , Gang Zhao
发明人: Xiaojiang Han , Hong Ding , Gang Zhao
IPC分类号: H04W36/00
CPC分类号: H04W36/0055 , H04W36/0072 , H04W72/04 , H04W92/20
摘要: A method and apparatus for handover between base stations are disclosed. The method includes: a first base station sending handover request messages to neighboring base stations (401); the neighboring base stations judging whether to accept the handover according to information in the handover request messages, and sending judgment results to the first base station through request response messages (402); the first base station determining one destination base station from the neighboring base stations which are able to accept the handover, and sending a confirmation handover message to the destination base station (403); the destination base station allocating resources for a user equipment after receiving the confirmation handover message, and sending the allocated resources to the first base station through a confirmation handover response message (404); and the first base station indicating that the user equipment hands over to the destination base station after receiving the confirmation handover response message (405).
摘要翻译: 公开了一种在基站之间切换的方法和装置。 该方法包括:向邻近基站(401)发送切换请求消息的第一基站; 相邻基站根据切换请求消息中的信息来判断是否接受切换,并通过请求响应消息将判断结果发送给第一基站(402); 所述第一基站从能够接受切换的相邻基站确定一个目的地基站,并向目的地基站(403)发送确认切换消息; 所述目的地基站在接收到所述确认切换消息之后为用户设备分配资源,并且通过确认切换响应消息将所分配的资源发送到所述第一基站; 并且第一基站指示用户设备在接收到确认切换响应消息之后切换到目的地基站(405)。
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公开(公告)号:US20130026774A1
公开(公告)日:2013-01-31
申请号:US13521503
申请日:2010-02-12
申请人: Hong Ding
发明人: Hong Ding
IPC分类号: B66C1/04
CPC分类号: B66C1/04 , H01F7/0257
摘要: The present invention provides a kind of permanent magnetic lifting device, which has: a housing, at the bottom of which is a clamping surface for clamping objects; fixed magnet(s), set in housing relatively fixed to housing; a turnable magnet, set in housing relatively turnable to fixed magnet. When turnable magnet is in the first position relative to fixed magnet, the magnetic force generated by fixed magnet and turnable magnet to clamping surface is zero magnetic force; when turnable magnet is in the third position relative to fixed magnet, the magnetic force generated by fixed magnet and turnable magnet to clamping surface is the maximum magnetic force. The permanent magnetic lifting device also has a positioning mechanism for second position. When the positioning mechanism for second position positions turnable magnet in the second position relative to fixed magnet, fixed magnet and turnable magnet generate trial clamping magnetic force to clamping surface for clamping objects on trial. The trial clamping magnetic force is higher than zero magnetic force and lower than maximum magnetic force. The permanent magnetic lifting device enables an operator to easily operate trial clamping, and also to know whether the ratio of the maximum clamping force that can be generated by the permanent magnetic lifting device under the specific condition to the weight of the workpiece equals or exceeds 2 times or 3 times or other specific values, and through operation of trial clamping, potential risk in safety can be thoroughly eliminated.
摘要翻译: 本发明提供一种永磁提升装置,其具有:壳体,其底部是夹紧物体的夹紧面; 固定磁体,设置在与壳体相对固定的壳体中; 固定在壳体内的可转动磁体可相对转动到固定磁体。 当可转动磁体相对于固定磁体位于第一位置时,由固定磁体和可转动磁体产生的夹紧磁力对零位磁力; 当可转动磁体相对于固定磁体位于第三位置时,由固定磁铁和可转动磁体产生的夹紧磁力对夹紧表面是最大的磁力。 永磁提升装置还具有用于第二位置的定位机构。 当第二位置的定位机构将可转动磁体相对于固定磁体位于第二位置时,固定磁铁和可转动磁体在试验中产生用于夹紧物体的夹紧表面的试验夹紧磁力。 试验夹紧磁力高于零磁力,低于最大磁力。 永磁提升装置使得操作者能够容易地操作试验夹紧,并且还知道在特定条件下由永磁提升装置产生的最大夹紧力与工件重量的比值是否等于或大于2 次或3次或其他具体值,通过试用夹持操作,可以彻底消除安全隐患。
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