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公开(公告)号：US5540265A
公开(公告)日：1996-07-30
申请号：US81747
申请日：1993-06-23
CPC分类号： A61M1/1656 , A61M1/1666 , A61M1/167 , A61M39/26 , F16L37/32 , A61M2039/1005 , A61M2205/6045
摘要： The invention concerns a bag to accommodate solid or fluid concentrate which is used to prepare dialysis fluid using a dialysis machine. The bag consists of a bag body and at least one opening, whereby the opening is sealingly surrounded by a plug component (220). In the coupled state with a second plug component (210), the plug component (220) forms a flow connection with the interior of the bag. The plug component also has coupling means (276, 278) which are suitable to be connected with a second complementary plug component (210), which is disposed on the dialysis machine. By means of the plug connector, in the coupled state, a first flow path is formed from the dialysis machine to the interior of the bag and a second flow path is formed back from the interior of the bag to the dialysis machine.
摘要翻译： 本发明涉及用于容纳固体或液体浓缩物的袋子，其用于使用透析机制备透析液。 该袋由袋体和至少一个开口组成，由此开口被塞子部件（220）密封地包围。 在具有第二插头部件（210）的联接状态下，插头部件（220）与袋子的内部形成流动连接。 插塞部件还具有耦合装置（276,278），其适于与设置在透析机上的第二互补插塞部件（210）连接。 通过插头连接器，在联接状态下，从透析机到袋的内部形成第一流路，并且从袋的内部向透析机形成第二流路。
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公开(公告)号：US5480565A
公开(公告)日：1996-01-02
申请号：US134098
申请日：1993-10-08
CPC分类号： B01D65/022 , A61M1/1686 , A61M1/169 , B01D2321/16 , B01D2321/162
摘要： A method for reprocessing dialyzer cartridges used with kidney dialysis machines is provided. The method involves filling the blood and dialysate compartments of the dialyzer with an aqueous solution containing citric acid at a concentration of 1.0-5.0 wt. %, e.g., 1.5 wt. %, and then subjecting the dialyzer to an elevated temperature above 90.degree. C. and below 100.degree. C., e.g., 95.degree. C., for a period of at least 15 hours, e.g., 20 hours. Although citric acid is non-toxic and the temperature used is below the boiling point of water, the process has been found to produce a fully sterilized dialyzer. After reprocessing, the aqueous citric acid solution is preferably left in the dialyzer where it acts as a bacteriostatic agent during storage. Essentially no damage to the dialyzer and, in particular, to its semipermeable membrane results from either the reprocessing or storage procedures.
摘要翻译： 提供了一种用于肾脏透析机使用的再利用透析器盒的方法。 该方法包括用浓度为1.0-5.0wt。柠檬酸的水溶液填充透析器的血液和透析液室。 ％，例如1.5wt。 ％，然后使透析器在高于90℃和低于100℃，例如95℃的升高温度下进行至少15小时，例如20小时的时间。 虽然柠檬酸是无毒的，使用的温度低于水的沸点，但已发现该方法生产完全灭菌的透析器。 再处理后，优选将柠檬酸水溶液置于透析器中，在储存期间用作抑菌剂。 透析器基本上没有损害，特别是对其半透膜造成的后果是再次处理或储存。
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公开(公告)号：US5336194A
公开(公告)日：1994-08-09
申请号：US97673
申请日：1993-07-27
CPC分类号： A61M39/0208 , A61M5/165 , A61M2039/0211 , A61M2039/0241
摘要： Implantable infusion apparatus comprising a chamber sealed by a septum and having an outlet aperture leading therefrom, to which a catheter tube is connected. A wire anchored in the chamber base projects into the catheter lumen, forming a ring slot whose diameter is smaller than the average size of a punched out particle. The wire thus serves as a particle retention means.
摘要翻译： 植入式输注装置，其包括由隔膜密封并且具有从其导出的出口孔的腔室，导管管连接到该腔室。 锚固在腔室基部中的线突出到导管腔中，形成直径小于穿孔颗粒的平均尺寸的环槽。 因此，丝线用作颗粒保持装置。
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44.发明授权
公开(公告)号：US5230341A
公开(公告)日：1993-07-27
申请号：US660240
申请日：1991-02-25
CPC分类号： A61M1/16 , A61M1/361 , A61M1/3612
摘要： To determine in simple manner the change of the intravascular blood volume during filtration, in the extracorporeal blood circuit (2) of a blood purification apparatus at least one ultrasonic sensor (15) is arranged which is connected to an evaluating unit (18) which is configured in such a manner that at the start of the filtration a first ultrasonic signal is stored and during the filtration the change of the ultrasonic signals is determined. From the change of the ultrasonic signals the change of the hematocrit is determined and from this the change of the intravascular blood volume is deduced.
摘要翻译： 为了简单地确定过滤期间血管内血液体积的变化，在血液净化装置的至少一个超声波传感器（15）的体外血液回路（2）中布置有与评估单元（18）连接的评估单元 以这样的方式构造，使得在开始过滤时存储第一超声波信号，并且在过滤期间确定超声波信号的变化。 根据超声波信号的变化，确定血细胞比容的变化，从而推断出血管内血容量的变化。
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公开(公告)号：US5100554A
公开(公告)日：1992-03-31
申请号：US615450
申请日：1990-11-19
CPC分类号： A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1615 , A61M1/1617
摘要： This invention relates to a method for the in-vivo determination of hemodialysis parameters. To carry out hemodialysis with the greatest efficiency and safety, it is inter alia necessary to know the clearance of the dialyzer. To be able to determine the same in vivo, the invention provides a method in which the electrolyte transfer of the dialysis fluid is measured by means of a measuring device at two different predetermined dialysis fluid ion concentrations and the dialysance is determined on the basis thereof, which dialysance is numerically equal to the clearance.
摘要翻译： 本发明涉及血液透析参数的体内测定方法。 要以最大的效率和安全性进行血液透析，除其他外，还需要了解透析器的清除率。 为了能够在体内确定相同的方法，本发明提供了一种方法，其中通过两种不同预定透析流体离子浓度的测量装置测量透析液的电解质转移，并且基于此确定透析性， 哪种透析在数值上等于间隙。
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46.发明授权Device for inputting numerical or alphanumerical data, respectively into an apparatus 失效用于将数字或字母数字数据分别输入到装置中的装置
公开(公告)号：US4916440A
公开(公告)日：1990-04-10
申请号：US224094
申请日：1988-07-26
IPC分类号： G06F3/0362 , G06F3/038
CPC分类号： G06F3/038 , G06F3/0362 , G06F3/0383
摘要： The tapped voltage representing the displacement and duration of a potentiometer in a joystick-type actuating element is applied to an analog to digital converter and the converted digital value is fed to preset inputs of a presettable digital counter which is set at its counting inputs by a clock generator. The overflow output of the presettable counter is connected to a load input of the presettable counter and to an up/down counter which controls a display or the like via decoding and driver circuits. A subtracting circuit is provided to subtract a preselected value from the converted digital value in order to provide a dead zone for a preselected range of the potentiometer.
摘要翻译： 表示操纵杆式致动元件中的电位计的位移和持续时间的抽头电压被施加到模数转换器，并且转换的数字值被馈送到预设的数字计数器的预设输入端，该可预置数字计数器在其计数输入处被设置为 时钟发生器。 可预置计数器的溢出输出连接到可预设计数器的负载输入端，以及通过解码和驱动电路控制显示器等的上/下计数器。 提供减法电路以从转换的数字值中减去预选值，以便为电位器的预选范围提供死区。
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公开(公告)号：US4834888A
公开(公告)日：1989-05-30
申请号：US128131
申请日：1987-12-03
CPC分类号： A61M1/16 , A61M1/165 , A61M1/1672 , A61M2205/705 , A61M2205/7554 , A61M2205/7563
摘要： A hemodialysis apparatus includes a sterile filter whose outlet, which is usually closed, is connected to a line leading to a discharge outlet in wherein a bypass valve is employed which can be opened at predetermined intervals both during treatment and during flushing operations. The sterile filter has a primary chamber and a secondary chamber. When the bypass valve is opened during treatment, dialysis solution flows out of the primary chamber of the sterile filter and flushes the pyrogens and particles disposed on the membranes of the filter into the discharge. No sterilizating filtration of the dialysis solution takes place through the pores of the membrane because the flow resistance present in the adjoining dialyzer, in conjunction with a degree of clogging of the pores, prevents such a flow. A ventilation means may be provided whereby the bypass circuit of the sterile filter can be ventilated. The bypass circuit may also be employed for a pressure retaining test.
摘要翻译： 血液透析装置包括无菌过滤器，其通常封闭的出口连接到通向排出口的管线，其中使用旁通阀，其可以在处理期间和在冲洗操作期间以预定间隔打开。 无菌过滤器具有主室和次室。 当处理期间旁路阀打开时，透析溶液流出无菌过滤器的主室，并将设置在过滤器膜上的热原和颗粒冲洗到排放物中。 通过膜的孔没有发生透析溶液的消毒过滤，因为邻接的透析器中存在的流动阻力以及孔的堵塞程度阻止了这种流动。 可以提供通风装置，由此无菌过滤器的旁路回路可以通风。 旁路电路也可以用于压力保持测试。
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48.发明授权Measuring device for determination of the activity or of the concentration of ions in solutions 失效用于测定溶液中离子的活度或浓度的测量装置
公开(公告)号：US4797191A
公开(公告)日：1989-01-10
申请号：US732022
申请日：1985-05-08
申请人： Klaus Metzner , Detlef Westphal , Wolfgang Allendorfer , Reinhard Hahnel , Hans-Dietrich Polaschegg
发明人： Klaus Metzner , Detlef Westphal , Wolfgang Allendorfer , Reinhard Hahnel , Hans-Dietrich Polaschegg
IPC分类号： G01N27/416 , A61M1/14 , A61M1/16 , A61M1/36 , G01N27/28 , G01N27/403 , G01N33/48 , G01N35/00 , G01N27/26
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/165 , A61M1/361 , A61M1/3612 , Y10T436/255
摘要： Measuring device for determination of the activity or of the concentration of ions in solutions, which has an electrode block having several electrodes and with a flow channel, the flow channel being in connection at its one end with a sample vessel and is connected at its other end to a line, in which a pump is interposed, with calibrating solution containers.Between the pump and the outlet of the electrode block branches off a discharge line, in which a further pump is interposed. Preferably, both pumps are combined into a peristaltic pump, the lines being laid in the segments of the pump.According to a second embodiment, the electrode block is again in connection with the calibrating solution containers. The delivery of the sample is performed however on the same side through a septum. Advantageously, the other side of the electrode block opens out into a pressure equalization vessel, into which a withdrawal line opens in which in turn the above mentioned peristaltic pump is interposed.
摘要翻译： 用于测定溶液中活性或离子浓度的测量装置，其具有具有多个电极和流动通道的电极块，所述流动通道在其一端与样品容器连接并且在另一端连接 在其中插入泵的管路与校准溶液容器结合。 在电极块的泵和出口之间分支一个排出管，其中插入另一个泵。 优选地，两个泵组合成蠕动泵，线路被放置在泵的段中。 根据第二实施例，电极块再次与校准溶液容器连接。 然而，通过隔膜在同一侧进行样品的输送。 有利地，电极块的另一侧向外打开压力平衡容器，抽出管线打开，其中插入上述蠕动泵。
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49.发明授权Apparatus for the drawing off of untreated and treated dialyzing liquid and/or blood from a dialysis device 失效用于从透析装置抽出未经处理和处理的透析液体和/或血液的装置
公开(公告)号：US4662208A
公开(公告)日：1987-05-05
申请号：US732025
申请日：1985-05-08
申请人： Klaus Metzner , Detlef Westphal , Wolfgang Allendorfer , Reinhard Hahnel , Hans-Dietrich Polaschegg
发明人： Klaus Metzner , Detlef Westphal , Wolfgang Allendorfer , Reinhard Hahnel , Hans-Dietrich Polaschegg
IPC分类号： G01N27/416 , A61M1/14 , A61M1/16 , A61M1/36 , G01N27/28 , G01N27/403 , G01N33/48 , G01N35/00 , B01D13/00 , G01N33/49
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/165 , A61M1/361 , A61M1/3612 , Y10T436/255
摘要： An apparatus (1) for the drawing off of untreated and treated dialyzing liquid and/or blood from a dialysis device (1) has a dialyzer, from which a first line (22) goes off upstream and a second line (24) goes off downstream, which join into a third line (54). The third line (54) is connected to an analysis device (57). In each of the first and second lines is provided a pump (26, 28) and a shut-off element (56, 56'), between which an overflow (38, 40) per line is arranged. This on the one hand ensures that the liquid in the lines (22, 24) are kept constantly in motion, which prevents the formation of line blockages in the case of liquids tending to coagulate, and on the other hand considerably reduces the displacement time of the liquid to be investigated to the analysis device (57).
摘要翻译： 用于从透析装置（1）中抽出未处理和处理的透析液体和/或血液的装置（1）具有透析器，第一管线（22）从该透析器从上游流出，第二管线（24）从该透析器脱离 下游，加入第三行（54）。 第三线（54）连接到分析装置（57）。 在每个第一和第二管路中设置有泵（26,28）和截止元件（56,56'），每条线路之间布置有溢流（38,40）。 这一方面确保了管线（22,24）中的液体保持恒定运动，这防止在液体趋于凝结的情况下形成管线堵塞，另一方面大大减少了 待分析液体（57）。
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公开(公告)号：US4634430A
公开(公告)日：1987-01-06
申请号：US709167
申请日：1985-03-07
CPC分类号： A61M1/106 , F04B43/06 , F04B43/067 , Y10S128/12
摘要： Pump arrangement (10) for medical purposes, in particular blood or infusion pump, comprising a pump housing (12) having two pump chambers (16, 18), of which the work chamber (16) is subjected to the liquid to be pumped while the drive chamber (18) is connected via a connecting conduit to a pneumatic pump (14) of restricted pumping volume.This connecting conduit (50) comprises a valve (56) which is opened at the respective changeover point (top and bottom dead-center) of the pump (14) to set the entire pump arrangement (16) to atmospheric pressure.
摘要翻译： 用于医疗目的的泵装置（10），特别是血液或输注泵，包括具有两个泵室（16,18）的泵壳体（12），其中工作室（16）经受待泵送的液体，同时 驱动室（18）经由连接导管连接到限制抽吸量的气动泵（14）。 该连接管道（50）包括在泵（14）的相应切换点（上下死点）打开以将整个泵装置（16）设置为大气压力的阀（56）。
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