Devices and methods for delivering medical agents
    41.
    发明授权
    Devices and methods for delivering medical agents 有权
    用于递送医疗药剂的装置和方法

    公开(公告)号:US07850656B2

    公开(公告)日:2010-12-14

    申请号:US11118125

    申请日:2005-04-29

    IPC分类号: A61M5/00

    摘要: Described are novel methods for delivering a medical agent to a plurality of locations within a patient tissue volume such as the interior space of a spinal disc, and also for removing material therefrom during medical agent delivery to enhance the delivery. Also described are medical delivery devices such as needle assemblies configured to facilitate the regional delivery of medical agents to patient tissue.

    摘要翻译: 描述了用于将医疗剂递送到患者组织体积(例如脊椎盘的内部空间)内的多个位置的新方法,并且还用于在医疗剂递送期间从其中移除材料以增强输送。 还描述了医疗输送装置,例如构造成便于将医疗药剂区域递送到患者组织的针组件。

    Method for treating facet pain
    44.
    发明申请
    Method for treating facet pain 有权
    治疗面疼痛的方法

    公开(公告)号:US20080177218A1

    公开(公告)日:2008-07-24

    申请号:US11589410

    申请日:2006-10-30

    IPC分类号: A61N1/30

    CPC分类号: A61B17/56 A61B2017/564

    摘要: A method for treating a facet pain in a subject by providing an effective amount of therapeutic agent in manner that by a biological repair effect on the facet is produced as compared to a temporary anti-inflammatory effect.

    摘要翻译: 与临时抗炎作用相比,产生通过以方面的生物修复作用提供有效量的治疗剂来治疗受试者的小平面疼痛的方法。

    Flowable composition that hardens on delivery to a target tissue site beneath the skin
    46.
    发明授权
    Flowable composition that hardens on delivery to a target tissue site beneath the skin 有权
    可流动的组合物在皮肤递送至目标组织部位时变硬

    公开(公告)号:US09161903B2

    公开(公告)日:2015-10-20

    申请号:US12262705

    申请日:2008-10-31

    摘要: Flowable compositions and methods are provided for delivering a therapeutic agent at or near a target tissue site beneath the skin of a patient, the flowable composition comprising (i) a solvent and (ii) an effective amount of the therapeutic agent, the flowable composition being capable of hardening to form a drug depot at a physiological temperature or as solvent contacts bodily fluid at or near the target tissue site, wherein the drug depot is capable of releasing the therapeutic agent over a period of at least one day and the target tissue site comprises at least one muscle, ligament, tendon, cartilage, spinal disc, spinal foraminal space near the spinal nerve root, facet or synovial joint, or spinal canal. In some embodiments, an implantable drug depot for delivering a therapeutic agent is provided, the implantable drug depot comprising (i) a chamber; and (ii) a flowable composition comprising an effective amount of a therapeutic agent disposed within the chamber of the drug depot, the flowable composition capable of hardening when the drug depot is delivered at or near the target tissue site.

    摘要翻译: 提供可流动的组合物和方法用于在患者皮肤下方的靶组织部位处或附近递送治疗剂,所述可流动组合物包含(i)溶剂和(ii)有效量的治疗剂,所述可流动组合物为 能够在生理温度下硬化形成药物贮库,或者作为溶剂与目标组织部位处或附近的体液接触,其中药物贮库能够在至少一天的时间内释放治疗剂,并且靶组织部位 包括至少一个肌肉,韧带,肌腱,软骨,脊椎盘,脊神经根附近的脊椎孔隙空间,小面或滑膜关节或椎管。 在一些实施方案中,提供了用于递送治疗剂的可植入药物贮库,所述可植入药物贮库包括(i)室; 和(ii)可流动组合物,其包含设置在所述药物贮库的所述室内的有效量的治疗剂,所述可流动组合物能够在所述药物贮库在所述靶组织部位处或附近递送时硬化。

    Dental implant with hinged stablizing arms
    47.
    发明授权
    Dental implant with hinged stablizing arms 有权
    具有铰链稳定臂的牙种植体

    公开(公告)号:US08678821B2

    公开(公告)日:2014-03-25

    申请号:US12857715

    申请日:2010-08-17

    IPC分类号: A61C8/00

    摘要: An implant includes a collar configured for disposal within tissue. The collar defines an axial bore. A shaft extends between a first end and a second end. The shaft is configured for disposal with the bore of the collar. A base defines an axial bore having an inner surface configured for engagement with the shaft such that the base is axially movable relative to the shaft. At least one arm extends between the collar and the base. The at least one arm is movable via axial movement of the base relative to the shaft between a first position and a second position such that the at least one arm is expanded in a configuration to engage tissue. Methods of use are also disclosed.

    摘要翻译: 植入物包括构造成在组织内处置的套环。 轴环限定轴向孔。 轴在第一端和第二端之间延伸。 轴被配置为与套环的孔一起处理。 基部限定轴向孔,其具有构造成用于与轴接合的内表面,使得基座相对于轴可轴向移动。 至少一个臂在套环和底座之间延伸。 所述至少一个臂可以通过所述基座相对于所述轴在第一位置和第二位置之间的轴向运动而移动,使得所述至少一个臂在构造中扩张以接合组织。 还公开了使用方法。

    Bone scoring device
    49.
    发明授权
    Bone scoring device 有权
    骨骼评分装置

    公开(公告)号:US08551098B2

    公开(公告)日:2013-10-08

    申请号:US12857741

    申请日:2010-08-17

    IPC分类号: A61B17/16

    CPC分类号: A61B17/1659

    摘要: A bone scoring device having a body, a scoring member configured to engage a bone surface and a first biasing member connected to and configured to rotate the scoring member is provided. The scoring member being axially movable between a first, non-rotatable position, such that the scoring member is engaged with the body and a second rotatable position such that the scoring member is released from engagement with the body and freely rotates. The scoring member having an abrasive surface to score the surface of the bone in which it is put in contact. A method for using the scoring device as well as a kit including the scoring device are also provided.

    摘要翻译: 本发明提供了一种具有身体的骨骼刻痕装置,被配置为接合骨表面的划痕部件和连接到并构造成旋转刻划部件的第一偏压部件。 所述刻痕构件可在第一不可旋转位置之间轴向移动,使得所述刻划构件与所述主体接合,并且所述第二可旋转位置使得所述刻划构件与所述主体脱离接合并自由旋转。 所述评分构件具有研磨表面以对与其接触的骨的表面进行计分。 还提供了使用评分装置的方法以及包括评分装置的工具箱。