Temperature-Controlled Incubator Having An Arcuate Closure Panel
    41.
    发明申请
    Temperature-Controlled Incubator Having An Arcuate Closure Panel 有权
    具有弧形闭合面板的温度控制孵化器

    公开(公告)号:US20090068074A1

    公开(公告)日:2009-03-12

    申请号:US11869300

    申请日:2007-10-09

    IPC分类号: B01J19/00

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品,在规定温度下规定时间孵育样品,进行分析物分离程序,以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment
    42.
    发明授权
    Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment 有权
    将流体引入包含在温度受控环境中的反应容器中的方法

    公开(公告)号:US08309358B2

    公开(公告)日:2012-11-13

    申请号:US11928219

    申请日:2007-10-30

    IPC分类号: G01N35/02

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站,在规定温度下培养样品规定的时间,进行分析物分离程序,并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Temperature-controlled incubator having rotatable door
    43.
    发明授权
    Temperature-controlled incubator having rotatable door 有权
    带温度控制的孵化器具有可旋转的门

    公开(公告)号:US08012419B2

    公开(公告)日:2011-09-06

    申请号:US11772453

    申请日:2007-07-02

    IPC分类号: C12M1/36

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站,在规定温度下培养样品规定的时间,进行分析物分离程序,并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Temperature-controlled incubator having a receptacle mixing mechanism
    44.
    发明授权
    Temperature-controlled incubator having a receptacle mixing mechanism 有权
    具有容器混合机构的温度控制培养箱

    公开(公告)号:US08337753B2

    公开(公告)日:2012-12-25

    申请号:US11875285

    申请日:2007-10-19

    IPC分类号: C12M1/36

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站,在规定温度下培养样品规定的时间,进行分析物分离程序,并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Method for agitating the contents of a reaction receptacle within a temperature-controlled environment
    45.
    发明授权
    Method for agitating the contents of a reaction receptacle within a temperature-controlled environment 有权
    在温度控制环境下搅拌反应容器的内容物的方法

    公开(公告)号:US08318500B2

    公开(公告)日:2012-11-27

    申请号:US11875306

    申请日:2007-10-19

    IPC分类号: G01N35/02

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站,在规定温度下培养样品规定的时间,进行分析物分离程序,并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Temperature-Controlled Incubator Having Rotatable Door
    46.
    发明申请
    Temperature-Controlled Incubator Having Rotatable Door 有权
    具有可旋转门的温度控制孵化器

    公开(公告)号:US20090130749A1

    公开(公告)日:2009-05-21

    申请号:US11772453

    申请日:2007-07-02

    IPC分类号: C12M1/00

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品,在规定温度下规定时间孵育样品,进行分析物分离程序,以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Incubator for use in an automated diagnostic analyzer
    47.
    发明授权
    Incubator for use in an automated diagnostic analyzer 有权
    用于自动诊断分析仪的孵化器

    公开(公告)号:US07267795B2

    公开(公告)日:2007-09-11

    申请号:US10073346

    申请日:2002-02-13

    IPC分类号: C12M1/36

    摘要: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译: 用于执行多个诊断测定的自动分析仪同时包括多个站或模块,其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品,在规定温度下规定时间孵育样品,预处理分析物分离程序以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置,用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置,以及 用于在温度受控的环境中容纳试剂容器的装置,并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行,用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前,将分离的分析物加入扩增试剂。

    Data cartridge library having a pivoting cartridge transport

    公开(公告)号:US06229666B1

    公开(公告)日:2001-05-08

    申请号:US09401954

    申请日:1999-09-23

    IPC分类号: G11B1568

    CPC分类号: G11B15/6835 G11B15/68

    摘要: A cartridge library comprises plural cells for accommodating therein a cartridge of information storage media and a tape drive which transduces information relative when a cartridge is loaded into the drive. A cartridge loader (also known as the cartridge transport assembly) is mounted to the drive assembly for picking a selected cartridge from one of the cells and for inserting the selected cartridge into a cartridge slot in the drive. The drive assembly is stationary but the cartridge loader is pivotal about the drive assembly, and particularly about a pivot axis which is parallel to a center line of the data cartridge when the data cartridge is inserted into the drive assembly. The drive assembly includes a toothed transport track engageable by the cartridge transport assembly for incremental pivotal motion of the cartridge transport assembly about the pivot axis. The library also has a wall connected to the library frame, the wall having a series of windows formed in predetermined relationship with the cells of the magazine. The windows are used to detect a status (e.g., presence, absence, misinsertion) of the data cartridge in the magazine. In addition, the series of windows are employed for detecting a position of the cartridge transport assembly about the pivot axis. The cartridge transport assembly comprises a carriage first section and a carriage second section which is translatable relative to the carriage first section. A pair of cartridge engagement arms are mounted to the carriage second section for selectively partially inserting the data cartridge into the drive assembly. The cartridge transport assembly further includes a secondary cartridge contact member (forming part of a “flipper assembly”) which operates in response to movement of the engagement arm to moves the selected cartridge from partial insertion to full insertion into the drive. Also, the secondary cartridge contact member serves as a stop surface when the cartridge is ejected from the drive.

    Tape cartridge magazine with structure to prevent improper loading of
cartridges
    49.
    发明授权
    Tape cartridge magazine with structure to prevent improper loading of cartridges 失效
    盒式磁带盒结构,防止墨盒不正确装入

    公开(公告)号:US6144521A

    公开(公告)日:2000-11-07

    申请号:US121966

    申请日:1998-07-24

    IPC分类号: G11B15/68 G11B17/30 G11B23/04

    摘要: An automated library which handles cartridges of information storage media includes a magazine (40) which comprises a cartridge engaging member (1428) which deflects to preclude insertion of the magazine into a magazine cavity (840) in the library frame (36) when the cartridge is improperly inserted into the magazine. The magazine defines a cell for the cartridge and comprises a magazine wall (1420) from which cell partitions (1410) extend. The cartridge engaging member (1428) is a cantilevered arm having a distal end extending in a direction into which the cartridge is insertable into the cell, and has a cartridge engaging profile whereby, when a cartridge (C) is properly inserted into the cell, the cantilevered arm does not extend beyond a reference plane but when the cartridge is not properly inserted the cantilevered arm deflects beyond a reference plane. The magazine wall has an arcuate shape, and has plural cell partitions for defining plural cells, with mouths of the plural cells being angularly arranged about an axis (100). The magazine wall has spaced apart ribs (1460) with a cartridge window (1664) formed between adjacent ribs. In addition, the magazine wall has at least one handle fin (1470) extending therefrom. A trough (848) is formed at a first edge of the magazine-receiving aperture of the library frame accommodates a semi-cylindrical protrusion (1476) on the magazine. Upon insertion the semi-cylindrical protrusion pivots in the trough. The library frame has a lock (860) proximate the second edge of the magazine-receiving aperture for locking the magazine into the magazine-receiving aperture.

    摘要翻译: 一种处理信息存储介质盒的自动库,包括一个盒子(40),该盒子包括一个盒接合件(1428),当盒子(3)的盒 被错误插入杂志。 盒子定义了盒的盒,并且包括盒壁(1420),盒壁(1410)从该盒壁延伸。 盒式接合构件(1428)是悬臂,悬臂具有沿着盒可插入电池的方向延伸的远端,并且具有盒接合轮廓,由此当盒(C)被适当地插入到电池中时, 悬臂不延伸超过参考平面,但是当盒未正确插入时,悬臂臂偏转超过参考平面。 杂志壁具有弓形形状,并且具有用于限定多个单元的多个单元分隔件,多个单元的口围绕轴线(100)成角度地布置。 杂物箱壁具有间隔开的肋(1460),其中相邻肋之间形成有盒窗口(1664)。 此外,刀库壁具有从其延伸的至少一个手柄翅片(1470)。 在库框架的料盒接收孔的第一边缘处形成槽(848),容纳在料盒上的半圆柱形突起(1476)。 在插入时,半圆柱形突起枢转在槽中。 书架框架具有邻近料盒接收孔的第二边缘的锁定件(860),用于将料盒锁定到料盒接收孔中。

    Reaction receptacle apparatus
    50.
    发明授权
    Reaction receptacle apparatus 有权
    反应容器装置

    公开(公告)号:US06517783B2

    公开(公告)日:2003-02-11

    申请号:US09802648

    申请日:2001-03-09

    IPC分类号: B01L300

    摘要: A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacles. Multiple receptacles are coupled to one another by a connecting rib structure that defines straight shoulders along opposite sides of the reaction receptacle apparatus, and the shoulders support the apparatus within reaction receptacle apparatus carrying structures. A contact-limiting element holding structure for holding contact-limiting elements, such as protective tips for tubular elements, is associated with each individual receptacle and holds a contact-limiting element in an operative orientation so as to be operatively engageable by the tubular element of the substance transfer device. A receptacle apparatus manipulating structure permits the reaction receptacle apparatus to be moved from one location to another by a robotic manipulating device, and an information panel presents a surface on which human and/or machine readable information may be placed.

    摘要翻译: 反应容器设备包括用于容纳化学或生物物质的一个或多个单独的容器。 一个或多个容器被布置成与用于将物质输送到单个容器中的物质转移装置的管状元件接合。 多个插座通过连接肋结构彼此联接,该连接肋结构沿着反应容器装置的相对侧限定了直的肩部,并且肩部将装置支撑在承载结构的反应容器装置内。 用于保持接触限制元件(例如管状元件的保护尖端)的接触限制元件保持结构与每个单独的接头相关联,并且将接触限制元件保持在可操作的方向上,以便可操作地通过管状元件的管状元件 物质转移装置。 容器设备操纵结构允许反应容器设备通过机器人操纵装置从一个位置移动到另一个位置,并且信息面板呈现可以放置人和/或机器可读信息的表面。