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公开(公告)号：US08420632B2
公开(公告)日：2013-04-16
申请号：US13381234
申请日：2010-06-28
申请人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlène Schuppli
发明人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlène Schuppli
IPC分类号： A61K31/551 , A61K31/4965 , A61K31/497 , C07D295/26 , C07D471/04 , C07D413/12 , C07D401/12 , C07D403/12
CPC分类号： C07D215/14 , A61K31/4965 , A61K31/497 , A61K31/551 , C07D209/10 , C07D209/12 , C07D209/20 , C07D209/24 , C07D209/26 , C07D213/30 , C07D213/55 , C07D213/56 , C07D213/68 , C07D261/20 , C07D295/15 , C07D295/26 , C07D471/04 , Y02A50/411
摘要： Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
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42.发明授权3-phenyl acrylic acid compound activators of type PPAR receptors and pharmaceutical/cosmetic compositions comprised thereof 失效类型PPAR受体的3-苯基丙烯酸化合物活化剂和由其组成的药物/化妆品组合物公开(公告)号：US08404836B2
公开(公告)日：2013-03-26
申请号：US12632257
申请日：2009-12-07
IPC分类号： C07D345/00 , C07D517/00
CPC分类号： C07C309/65 , A61K8/365 , A61K8/42 , A61K8/466 , A61Q5/02 , A61Q19/10 , C07C59/68 , C07C217/76 , C07C233/25 , C07C235/56 , C07C309/66 , C07C309/67 , C07C311/08 , C07C311/13
摘要： Novel 3-phenyl acrylic acid compounds have the following general formula (I): and are formulated into pharmaceutical compositions for administration in human or veterinary medicine (in dermatology, as well as in the field of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or into cosmetic compositions.
摘要翻译： 新型3-苯基丙烯酸化合物具有以下通式（I）：并配制成用于人或兽医药物（皮肤病学以及心血管疾病，免疫疾病和/或相关疾病）领域的药物组合物 与脂质代谢）或化妆品组合物。
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43.发明申请NOVEL BIAROMATIC COMPOUNDS THAT MODULATE PPARy TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF 失效调节PPARY型受体和包含其的化妆品/药物组合物的新型双组分化合物公开(公告)号：US20120121527A1
公开(公告)日：2012-05-17
申请号：US13353125
申请日：2012-01-18
IPC分类号： A61K31/381 , A61K8/49 , C07D307/52 , A61K31/341 , C07D213/53 , A61K31/44 , C07D239/24 , A61K31/505 , A61Q5/00 , A61Q19/00 , A61P17/00 , A61P3/04 , A61P3/10 , A61P29/00 , A61P35/00 , A61P37/00 , A61P9/10 , A61P9/12 , C07D333/22
CPC分类号： C07D333/24 , C07D213/55 , C07D213/75 , C07D239/26 , C07D239/42 , C07D307/54
摘要： Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/of diseases related to the metabolism of lipids), or, alternatively, in cosmetic compositions.
摘要翻译： 具有通式（I）的新型双芳族化合物及其包含的化妆品/药物组合物可用于人或兽医学（在皮肤病学领域以及心血管疾病，免疫疾病和/或与脂质代谢有关的疾病领域 ），或者在化妆品组合物中。
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公开(公告)号：US07294639B2
公开(公告)日：2007-11-13
申请号：US11505879
申请日：2006-08-18
IPC分类号： A61K31/44 , A61K31/38 , A61K31/215 , C07D211/70 , C07D333/08 , C07D307/02 , C07C229/00
CPC分类号： A61Q19/007 , A61K8/411 , A61K8/416 , A61K8/49 , A61K8/4913 , A61K8/4986 , A61K31/195 , A61K31/428 , A61K31/47 , A61K31/4965 , A61K31/5375 , A61K2800/70 , A61Q19/06 , A61Q19/08 , C07D277/34 , C07D417/12
摘要： Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPARγ receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.
摘要翻译： 新型药物/化妆品组合物含有至少一种PPARγ受体的双芳族配体活化剂，具有结构式（I）的双芳族配体：特别适用于调节和/或恢复皮肤脂质代谢，用于治疗广泛 各种皮肤病，以及用于预防和/或治疗老化和/或干性皮肤的症状。
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公开(公告)号：US20070043046A1
公开(公告)日：2007-02-22
申请号：US11505879
申请日：2006-08-18
IPC分类号： A61K31/5375 , A61K31/4965 , A61K31/47 , A61K31/428 , A61K31/195
CPC分类号： A61Q19/007 , A61K8/411 , A61K8/416 , A61K8/49 , A61K8/4913 , A61K8/4986 , A61K31/195 , A61K31/428 , A61K31/47 , A61K31/4965 , A61K31/5375 , A61K2800/70 , A61Q19/06 , A61Q19/08 , C07D277/34 , C07D417/12
摘要： Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPARγ receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.
摘要翻译： 新型药物/化妆品组合物含有至少一种PPARγ受体的双芳族配体活化剂，具有结构式（I）的双芳族配体：特别适用于调节和/或恢复皮肤脂质代谢，用于治疗广泛 各种皮肤病，以及用于预防和/或治疗老化和/或干性皮肤的症状。
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公开(公告)号：US20050137238A1
公开(公告)日：2005-06-23
申请号：US11042212
申请日：2005-01-26
IPC分类号： C07D277/34 , C07D417/12 , A61K31/426 , C07D277/36
CPC分类号： A61Q19/007 , A61K8/411 , A61K8/416 , A61K8/49 , A61K8/4913 , A61K8/4986 , A61K31/195 , A61K31/428 , A61K31/47 , A61K31/4965 , A61K31/5375 , A61K2800/70 , A61Q19/06 , A61Q19/08 , C07D277/34 , C07D417/12
摘要： Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPARγ receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.
摘要翻译： 新型药物/化妆品组合物含有至少一种PPARγ受体的双芳族配体活化剂，具有结构式（I）的双芳族配体：特别适用于调节和/或恢复皮肤脂质代谢，用于治疗广泛 各种皮肤病，以及用于预防和/或治疗老化和/或干性皮肤的症状。
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