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公开(公告)号:US10316331B2
公开(公告)日:2019-06-11
申请号:US15486804
申请日:2017-04-13
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine Chay , Artem Evdokimov , Stanislaw Flasinski , Uma R. Kesanapalli , Megan N. Schroder , Rachael N. Slightom , Nengbing Tao , Andrew M. Wollacott
Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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公开(公告)号:US10155960B2
公开(公告)日:2018-12-18
申请号:US15247500
申请日:2016-08-25
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine A. Chay , Todd A. Ciche , Uma R. Kesanapalli , Jennifer L. Lutke
IPC: C12N15/82 , C07K14/195 , C12Q1/6895 , A01N37/46 , C07K14/32 , A01N63/02 , G01N33/53
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
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公开(公告)号:US20180291395A1
公开(公告)日:2018-10-11
申请号:US15944114
申请日:2018-04-03
Applicant: MONSANTO TECHNOLOGY LLC
Inventor: David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC: C12N15/82 , C07K14/415 , C07K14/47 , C07K14/32 , C07K14/245 , C07K14/27 , C07K14/26
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号:US09777289B2
公开(公告)日:2017-10-03
申请号:US14945069
申请日:2015-11-18
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine Chay , Artem Evdokimov , Megan N. Schroder , Rachael N. Slightom , Uma R. Kesanapalli , Nengbing Tao , Andrew M. Wollacott , Stanislaw Flasinski
IPC: A01H5/00 , C12N15/00 , C12N5/02 , C12N5/04 , A01N37/18 , C11B1/00 , C07K1/00 , C13B10/00 , C08B30/00 , A23L3/34 , C12N15/82 , C07K14/00 , C07K14/32
CPC classification number: C12N15/8286 , C07K14/001 , C07K14/32 , Y02A40/162
Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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公开(公告)号:US09732355B2
公开(公告)日:2017-08-15
申请号:US14945061
申请日:2015-11-18
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine Chay , Artem Evdokimov , Megan N. Schroder , Rachael N. Slightom , Uma R. Kesanapalli , Nengbing Tao , Andrew M. Wollacott , Stanislaw Flasinski
IPC: A01H5/00 , C12N15/00 , C12N5/02 , C12N5/04 , A01N37/18 , C11B1/00 , C07K1/00 , C13B10/00 , C08B30/00 , A23L3/34 , C12N15/82 , C07K14/00 , C07K14/32
CPC classification number: C12N15/8286 , C07K14/001 , C07K14/32 , Y02A40/162
Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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公开(公告)号:US20250002932A1
公开(公告)日:2025-01-02
申请号:US18830256
申请日:2024-09-10
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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公开(公告)号:US20240352480A1
公开(公告)日:2024-10-24
申请号:US18628578
申请日:2024-04-05
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC: C12N15/82 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32
CPC classification number: C12N15/8286 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32 , C07K2319/00
Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号:US20240287539A1
公开(公告)日:2024-08-29
申请号:US18426976
申请日:2024-01-30
Applicant: Monsanto Technology LLC
Inventor: Gregory J. Bean , David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S. Milligan , Yong Yin
IPC: C12N15/82 , A01N63/50 , C07K14/195
CPC classification number: C12N15/8286 , A01N63/50 , C07K14/195
Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
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公开(公告)号:US20230301308A1
公开(公告)日:2023-09-28
申请号:US18176410
申请日:2023-02-28
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S. Milligan , Christina M. Taylor , Monika R. VanGordon , Kimberly M. Wegener , Brian E. Weiner
CPC classification number: A01N63/50 , C12N15/8286 , C12Q1/6895 , C07K14/32 , A01P7/04 , G01N33/68 , C12Q2600/13
Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.
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公开(公告)号:US20230203527A1
公开(公告)日:2023-06-29
申请号:US18052819
申请日:2022-11-04
Applicant: Monsanto Technology LLC
Inventor: David J. Bowen , Catherine A. Chay , Todd A. Ciche , Uma R. Kesanapalli , Jennifer L. Lutke
IPC: C12N15/82 , C12Q1/6895 , A01N37/46 , A01N63/50
CPC classification number: C12N15/8286 , C12Q1/6895 , A01N37/46 , A01N63/50 , C12Q2600/13 , G01N33/5308
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
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