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公开(公告)号：US20150025004A1
公开(公告)日：2015-01-22
申请号：US14190237
申请日：2014-02-26
Applicant: Meso Scale Technologies, LLC
Inventor： Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2333/4706 , G01N2333/4727 , G01N2333/70578 , G01N2333/70596 , G01N2333/8146 , G01N2800/347 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Abstract translation: 本发明涉及诊断患者肾脏疾病的方法，以及监测肾脏疾病进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。
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公开(公告)号：US11967410B2
公开(公告)日：2024-04-23
申请号：US15902597
申请日：2018-02-22
Applicant: Meso Scale Technologies, LLC. , THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
Inventor： William F Blakely , Eli N. Glezer , John Kenten , Sudeep Kumar , Anu Mathew , Natalia I. Ossetrova , George Sigal
CPC classification number: G16H20/40 , G01N27/3273 , G01N33/6893 , G01N35/00 , G01T1/00 , G01T1/02 , G01N2333/70535 , G01N2333/70578 , G01N2800/40 , G01N2800/60
Abstract: Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
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公开(公告)号：US20220397579A1
公开(公告)日：2022-12-15
申请号：US17773896
申请日：2020-11-04
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Sunsanee Kanjananimmanont , Sudeep Kumar , Navaratnam Manjula , Simone Barbero , Martin Stengelin , George Sigal
IPC: G01N33/68 , G01N33/543
Abstract: The invention relates to methods and kits for quantitating radiation exposure in a subject exposed to radiation, at risk of exposure to radiation or suspected of having been exposed to radiation. In embodiments, the present disclosure provides multiplexed immunoassays for quantifying amounts of biomarkers for assessing radiation exposure in a sample. Also provided herein are kits for performing the multiplexed assays.
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公开(公告)号：US20220390469A1
公开(公告)日：2022-12-08
申请号：US17890782
申请日：2022-08-18
Applicant: Meso Scale Technologies, LLC.
Inventor： Jeffrey Debad , Eli N. Glezer , Sudeep Kumar
IPC: G01N33/68 , G01N33/574
Abstract: The present invention relates to methods of diagnosing an inflammatory disorder in a patient, as well as methods of monitoring the progression of an inflammatory disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US11320366B2
公开(公告)日：2022-05-03
申请号：US16219030
申请日：2018-12-13
Applicant: Meso Scale Technologies, LLC.
Inventor： Nicholas Anderson , Jeffery Debad , Eli N. Glezer , Sudeep Kumar , Noel Lawrence , Kenneth Page , George Sigal , Sharon West
IPC: B01L9/00 , G01N21/05 , G01N21/69 , G01N21/76 , B01L3/00 , G01N21/03 , G01F23/02 , G01F23/292 , G01N1/10 , B01L7/00
Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.
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Patent Agency Ranking
公开(公告)号：US20210060567A1
公开(公告)日：2021-03-04
申请号：US17032524
申请日：2020-09-25
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20200158731A1
公开(公告)日：2020-05-21
申请号：US16748026
申请日：2020-01-21
Applicant: Meso Scale Technologies, LLC.
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin
IPC: G01N33/574 , A61K39/395
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20200035333A1
公开(公告)日：2020-01-30
申请号：US16594301
申请日：2019-10-07
Applicant: Meso Scale Technologies, LLC.
Inventor： Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
IPC: G16C20/20 , G01N35/00 , G01N33/543 , B01L3/00 , G16H10/40
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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公开(公告)号：US20200011866A1
公开(公告)日：2020-01-09
申请号：US16555271
申请日：2019-08-29
Applicant: MESO SCALE TECHNOLOGIES, LLC , THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
Inventor： William F. Blakely , Eli N. Glezer , John Kenten , Sudeep Kumar , Anu Mathew , Natalia I. Ossetrova , George Sigal
IPC: G01N33/569 , G01N33/68 , G01N33/566
Abstract: The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
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公开(公告)号：US10446263B2
公开(公告)日：2019-10-15
申请号：US14862298
申请日：2015-09-23
Applicant: Meso Scale Technologies, LLC
Inventor： Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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