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公开(公告)号:US6110507A
公开(公告)日:2000-08-29
申请号:US200284
申请日:1998-11-24
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
摘要: The present invention provides a human 3-hydroxyisobutyryl-coenzyme A hydrolase (HIBCOH) and polynucleotides which identify and encode HIBCOH. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for the prevention and treatment of diseases associated with expression of HIBCOH, as well as diagnostic assays.
摘要翻译: 本发明提供了一种人3-羟基异丁酰辅酶A水解酶(HIBCOH)和识别和编码HIBCOH的多核苷酸。 本发明还提供表达载体,宿主细胞和抗体。 本发明还提供了用于预防和治疗与HIBCOH表达相关的疾病以及诊断测定法的方法。
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公开(公告)号:US6033893A
公开(公告)日:2000-03-07
申请号:US883526
申请日:1997-06-26
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
IPC分类号: C12N15/09 , A61K38/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/57 , C12N9/48 , C07H21/04 , C12N1/20 , C12N15/00
CPC分类号: C12N9/6472 , C07K16/40 , A61K38/00
摘要: The invention provides a new human cathepsin (LCAP) and polynucleotides which identify and encode LCAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of LCAP.
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公开(公告)号:US5981244A
公开(公告)日:1999-11-09
申请号:US215087
申请日:1998-12-18
申请人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
发明人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
CPC分类号: C12N9/0006 , A61K38/00
摘要: The invention provides a human aflatoxin B1 aldehyde reductase (AFB1-hAR) and polynucleotides which identify and encode AFB1-hAR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of AFB1-hAR.
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公开(公告)号:US5965394A
公开(公告)日:1999-10-12
申请号:US933227
申请日:1997-09-18
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
摘要: The invention provides a human importin alpha homolog (IMPAH) and polynucleotides which identify and encode IMPAH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of IMPAH.
摘要翻译: 本发明提供了人类进一步的α同源物(IMPAH)和识别和编码IMPAH的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与IMPAH表达相关的疾病的方法。
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公开(公告)号:US5958725A
公开(公告)日:1999-09-28
申请号:US865336
申请日:1997-05-29
IPC分类号: C12N15/09 , A61K38/00 , A61K39/00 , A61K39/395 , A61K45/00 , A61P35/00 , C07K14/82 , C07K16/32 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/02 , C12Q1/68 , C12N15/00
摘要: The invention provides a human DPl homolog (DPlh)) and polynucleotides which identify and encode DPlh. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of DPlh.
摘要翻译: 本发明提供人DP1同系物(DP1h))和鉴定和编码DP1h的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与DP1h表达相关的疾病的方法。
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公开(公告)号:US5948619A
公开(公告)日:1999-09-07
申请号:US904031
申请日:1997-07-31
申请人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Purvi Shah
发明人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Purvi Shah
IPC分类号: C07K14/475 , C12Q1/68 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号: C07K14/4756
摘要: The invention provides a human zygin-1 (ZY-1H) and polynucleotides which identify and encode ZY-1H. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ZY-1H.
摘要翻译: 本发明提供了人zygin-1(ZY-1H)和鉴定和编码ZY-1H的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与ZY-1H表达相关的疾病的方法。
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公开(公告)号:US06235477B1
公开(公告)日:2001-05-22
申请号:US09270270
申请日:1999-03-16
申请人: Olga Bandman , Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah
IPC分类号: C12Q168
CPC分类号: C07K14/4728 , A61K38/00 , Y02A50/387 , Y02A50/465
摘要: The invention provides two human reticulocalbin isoforms designated individually as RCN &ggr; and RCN &dgr; and collectively as RCN, and polynucleotides which identify and encode RCN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RCN.
摘要翻译: 本发明提供了两种单独指定为RCNγ和RCNδ并统称为RCN的人reticulocalbin同种型,以及识别和编码RCN的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与RCN表达相关的疾病的方法。
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公开(公告)号:US5928899A
公开(公告)日:1999-07-27
申请号:US165234
申请日:1998-10-01
申请人: Jennifer L. Hillman , Olga Bandman , Preeti Lal , Purvi Shah , Neil C. Corley
发明人: Jennifer L. Hillman , Olga Bandman , Preeti Lal , Purvi Shah , Neil C. Corley
IPC分类号: G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/566 , C12N15/63 , C12N15/70
CPC分类号: C07K14/4738 , A61K38/00
摘要: The invention provides three human cell division regulators (HCDR) and polynucleotides which identify and encode HCDR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of HCDR.
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公开(公告)号:US06194186B1
公开(公告)日:2001-02-27
申请号:US08977816
申请日:1997-11-25
申请人: Preeti Lal , Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Purvi Shah
发明人: Preeti Lal , Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Purvi Shah
IPC分类号: C12N912
CPC分类号: C12N9/1205 , A61K38/00 , C07K14/4703 , C12Q1/6883
摘要: The invention provides a human protein kinase (PK) and kinase inhibitors (PKI) and polynucleotides which identify and encode PK and PKI. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PK and PKI.
摘要翻译: 本发明提供了鉴定和编码PK和PKI的人蛋白激酶(PK)和激酶抑制剂(PKI)和多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供用于诊断,治疗或预防与PK和PKI的表达相关的障碍的方法。
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公开(公告)号:US6121019A
公开(公告)日:2000-09-19
申请号:US274570
申请日:1999-03-23
申请人: Jennifer L. Hillman , Olga Bandman , Preeti Lal , Purvi Shah , Neil C. Corley
发明人: Jennifer L. Hillman , Olga Bandman , Preeti Lal , Purvi Shah , Neil C. Corley
IPC分类号: G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/566 , C07K14/435
CPC分类号: C07K14/4738 , A61K38/00
摘要: The invention provides three human cell division regulators (HCDR) and polynucleotides which identify and encode HCDR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of HCDR.
摘要翻译: 本发明提供三种人细胞分裂调节因子(HCDR)和识别和编码HCDR的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了用于预防和治疗与HCDR表达相关的疾病的方法。
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