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公开(公告)号：US20060193818A1
公开(公告)日：2006-08-31
申请号：US11312984
申请日：2005-12-20
CPC分类号： A61K31/13 , A61K8/41 , A61K8/97 , A61K31/522 , A61K36/06 , A61K36/42 , A61K36/77 , A61K36/82 , A61K45/06 , A61Q19/06 , A61Q19/08 , A61K2300/00
摘要： The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof for reducing the appearance discoloration or puffiness around the eye.
摘要翻译： 本发明的特征在于包含至少一种式I或式II化合物的组合物：其中R1，R2，R3，R4和R5独立地选自氢，C 1〜 C 6 -C 6烷基，C 1 -C 6羟基烷基或其化妆品可接受的盐及其用于减少外观变色或浮肿的用途 在眼睛周围。
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42.发明申请Method of screening compounds for potential efficacy for the treatment of signs of aging 审中-公开筛选化合物治疗老化迹象的潜在疗效的方法公开(公告)号：US20060193777A1
公开(公告)日：2006-08-31
申请号：US11066361
申请日：2005-02-25
申请人： Michael Southall , Eduardo Ruvolo , Binoy Bordoloi , Katharine Martin , Nikiforos Kollias , Elvin Lukenbach , Gloria Lukenbach
发明人： Michael Southall , Eduardo Ruvolo , Binoy Bordoloi , Katharine Martin , Nikiforos Kollias , Elvin Lukenbach , Gloria Lukenbach
CPC分类号： G01N33/5044 , A61K49/0006 , G01N33/5026
摘要： The present invention features a method of screening a compound for potential efficacy for the treatment of at least one sign of aging on the skin selected from the group consisting of enhancing the elasticity of said skin, enhancing the firmness of said skin, or reducing the appearance of wrinkles on the skin, said method comprising contacting one or more skin cells with said compound and measuring the ability of said compound to contract said one or more skin cells.
摘要翻译： 本发明的特征在于一种筛选化合物的方法，用于治疗选自以下的至少一种皮肤老化迹象的潜在功效：选自增强所述皮肤的弹性，增强所述皮肤的硬度或减少外观 所述方法包括使一种或多种皮肤细胞与所述化合物接触并测量所述化合物收缩所述一种或多种皮肤细胞的能力。
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公开(公告)号：US08221046B2
公开(公告)日：2012-07-17
申请号：US11223032
申请日：2005-09-09
申请人： Michael Southall , Katharine Martin , Phyllis Mitchell , Menas Kizoulis , Neena Tierney , Elvin R. Lukenbach , Binoy K. Bordoloi
发明人： Michael Southall , Katharine Martin , Phyllis Mitchell , Menas Kizoulis , Neena Tierney , Elvin R. Lukenbach , Binoy K. Bordoloi
CPC分类号： A61K31/132 , A61K8/41 , A61K31/133 , A61K36/28 , A61K36/48 , A61K45/06 , A61Q19/00 , A61Q19/06 , A61Q19/08 , A61K2300/00
摘要： The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof.
摘要翻译： 本发明的特征在于包含至少一种式I或式II化合物的组合物：其中R 1，R 2，R 3，R 4和R 5独立地选自氢，C 1 -C 6烷基，C 1 -C 6羟基烷基， 或其化妆品可接受的盐及其用途。
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公开(公告)号：US20120128605A1
公开(公告)日：2012-05-24
申请号：US13362338
申请日：2012-01-31
摘要： The present invention relates to a composition comprising a skin-lightening resorcinol and a skin darkening agent. The composition may be topically applied to the skin, such as to treat signs of aging.
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公开(公告)号：US20120064173A1
公开(公告)日：2012-03-15
申请号：US13291129
申请日：2011-11-08
摘要： The invention relates to methods and compositions for treating skin aging, said compositions comprising at least one tropoelastin promoter and at least one tropoelastin crosslinker.
摘要翻译： 本发明涉及用于治疗皮肤老化的方法和组合物，所述组合物包含至少一种原弹性蛋白启动子和至少一种托拉胶弹性蛋白交联剂。
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公开(公告)号：US20110236491A1
公开(公告)日：2011-09-29
申请号：US12842661
申请日：2010-07-23
申请人： Jeannette Chantalat , Jue-Chen Liu , May Shana'a , Michael Southall , Ying Sun
发明人： Jeannette Chantalat , Jue-Chen Liu , May Shana'a , Michael Southall , Ying Sun
CPC分类号： A61K45/06 , A61K8/0287 , A61K8/27 , A61K8/66 , A61K8/673 , A61K9/0014 , A61K33/30 , A61K33/34 , A61K33/38 , A61K38/44 , A61K38/443 , A61K41/0057 , A61K2800/412 , A61K2800/81 , A61N1/205 , A61Q19/08 , C12Y101/03004 , C12Y111/01006 , A61K2300/00
摘要： Compositions and methods for treating inflammation in mammalian tissue are provided using substantially continuously, in situ generated, anti-inflammatory effective amounts of hydrogen peroxide.
摘要翻译： 使用基本上连续，原位产生的抗炎有效量的过氧化氢提供用于治疗哺乳动物组织中的炎症的组合物和方法。
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公开(公告)号：US20100268335A1
公开(公告)日：2010-10-21
申请号：US12761601
申请日：2010-04-16
申请人： Chunlin Yang , Ying Sun , Frank R. Cichocki, JR. , Saumen N. Bar , James E. Hauschild , Uri Herzberg , Yufu Li , Xintian Ming , Wei Kong , Jeannette Chantalat , Michael Southall
发明人： Chunlin Yang , Ying Sun , Frank R. Cichocki, JR. , Saumen N. Bar , James E. Hauschild , Uri Herzberg , Yufu Li , Xintian Ming , Wei Kong , Jeannette Chantalat , Michael Southall
CPC分类号： A61L15/18 , A61B17/06066 , A61B17/06166 , A61B17/064 , A61B2017/00884 , A61B2017/00889 , A61L15/42 , A61L26/0004 , A61L26/0066 , A61L27/306 , A61L27/50 , A61L29/106 , A61L29/14 , A61L31/088 , A61L31/14 , A61L2300/404 , A61N1/205 , A61N1/303 , Y10T428/256 , Y10T428/2982
摘要： Implantable medical devices having galvanic particulates are disclosed. The particulates may be coated onto at least part of a surface of the medical device. In addition, the galvanic particulates may be contained in the material used to manufacture the antimicrobial medical devices, or may be embedded into the surface of the medical devices. The present invention also provides novel coating methods and processing methods. The devices may have advantageous characteristics and effects including anti-microbial, anti-inflammatory, and tissue regeneration promoting.
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公开(公告)号：US20070059259A1
公开(公告)日：2007-03-15
申请号：US11223665
申请日：2005-09-09
CPC分类号： A61K31/13 , A61K36/28 , A61K36/48 , A61K2300/00
摘要： The invention relates to a composition and a method for mitigating redness or inflammation of mammalian skin comprising administering to mammalian skin a composition consisting of an effective amount of alkanolamine, feverfew or soy or mixtures thereof, one or more optional benefit agents and one or more cosmetically acceptable carriers. More particularly, it relates to a composition for mitigating skin irritations such as retinol/retinoid irritation and their applications to mammalian skin.
摘要翻译： 本发明涉及减轻哺乳动物皮肤发红或炎症的组合物和方法，包括向哺乳动物皮肤施用由有效量的链烷醇胺，发烧或大豆或其混合物组成的组合物，一种或多种任选的有益剂和一种或多种化妆品 可接受的运营商。 更具体地说，本发明涉及一种用于缓解皮肤刺激（如视黄醇/类视黄醇刺激）及其在哺乳动物皮肤中的应用的组合物。
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49.发明申请公开(公告)号：US20060257335A1
公开(公告)日：2006-11-16
申请号：US11351862
申请日：2006-02-10
申请人： Michael Southall , Katharine Martin , Elvin Lukenbach , Binoy Bordoloi , Connie Lin , Richard Scarpa
发明人： Michael Southall , Katharine Martin , Elvin Lukenbach , Binoy Bordoloi , Connie Lin , Richard Scarpa
IPC分类号： A61K8/40
CPC分类号： A61K31/13 , A61K8/41 , A61K8/97 , A61K31/522 , A61K36/06 , A61K36/42 , A61K36/77 , A61K36/82 , A61K45/06 , A61Q19/06 , A61Q19/08 , A61K2300/00
摘要： The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof for darkening the skin.
摘要翻译： 本发明的特征在于包含至少一种式I或式II化合物的组合物：其中R1，R2，R3，R4和R5独立地选自氢，C 1〜 C 6 -C 6烷基，C 1 -C 6羟烷基或其化妆品可接受的盐，以及其用于使皮肤变黑的用途。
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公开(公告)号：US20060193814A1
公开(公告)日：2006-08-31
申请号：US11066362
申请日：2005-02-25
IPC分类号： A61K8/41
摘要： The present invention features a method of treating at least one sign of aging on the skin selected from the group consisting of enhancing the elasticity of said skin, enhancing the firmness of said skin, and reducing the appearance of wrinkles or cellulite on the skin, by administering to skin in need of such treatment a composition comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof.
摘要翻译： 本发明的特征在于一种治疗至少一种皮肤老化迹象的方法，所述衰老迹象选自由增强皮肤弹性，增强皮肤紧致度，减少皮肤上皱纹或脂肪团出现的组成， 向需要这种治疗的皮肤施用包含至少一种式I或式II化合物的组合物：其中R 1，R 2，R 3，R 4和R 5独立地选自氢，C 1 C 1 -C 6烷基，C 1 -C 6羟基烷基或其化妆品可接受的盐。
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