摘要:
A data gathering and processing system capable of efficiently gathering data and easily putting gathered data to secondary use in various applications. The data gathering and processing system includes an XML file generation unit that generates a structured document with data describing the layout of a data entry screen that includes input data, an item extraction unit that extracts, as a search item, at least a tag name from the structured document with data, an XML database that stores, in association with at least a portion of the structured document with data, the search item extracted by the item extraction unit from the structured document with data, a search criteria setting unit that receives a search item and a search criteria from a searcher, and a search execution unit that searches the XML database based on the search criteria, and presents input data obtained as a search result or a data entry screen that includes the input data.
摘要:
A protein having amino acid sequence in SEQ ID NO: 1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID NO: 1 of the Sequence Listing with a methionine at the N-terminus, introducing the plasmid into E. coli for transformation, solubilizing inclusion bodies obtained by culturing the transformant, purifying the monomer protein from the solubilized solution, refolding the monomer protein into a dimer protein and purifying the same. The homodimer protein described above is useful as a pharmaceutical composition for treating cartilage and bone diseases.
摘要翻译:衍生自人MP52的序列表的SEQ ID NO:1中具有氨基酸序列的蛋白质及其二聚体蛋白质。 可以通过在N末端构建含有序列表的SEQ ID NO:1的DNA编码氨基酸序列的质粒与甲硫氨酸在N末端引入,将质粒导入大肠杆菌进行转化,从而增溶包涵体 通过培养转化体获得,从溶解的溶液中纯化单体蛋白质,将单体蛋白重折叠成二聚体蛋白质并进行纯化。 上述同型二聚体蛋白质可用作治疗软骨和骨疾病的药物组合物。
摘要:
An image forming apparatus includes a photoconductor, a cleaning blade for cleaning the photoconductor, and a blade holder holding the cleaning blade and having a first bent portion for increasing its rigidity. In the apparatus, blade holder has at least one of a protrusion and a second bent portion.
摘要:
An object of the present invention is to provide an image forming apparatus containing an electrophotographic photoconductor, a charging unit, an exposing unit, a developing unit, a transfer unit and a cleaning unit, wherein the electrophotographic photoconductor contains a support and at least a photosensitive layer disposed on the support, wherein the photosensitive layer contains a charge generating material and a compound expressed by the following Structural Formula (1), and wherein, in the Structural Formula (1), “R1” and “R2” may be identical to each other or different, and represent any one of hydrogen atom, alkyl group which may be substituted, cycloalkyl group which may be substituted and aralkyl group which may be substituted. “R3”, “R4”, “R5”, “R6”, “R7”, “R8”, “R9”, “R10”, “R11”, “R12”, “R13” and “R14” may be identical to each other or different, and represent any one of hydrogen atom, halogen atom, cyano group, nitro group, amino group, hydroxyl group, alkyl group which may be substituted, cycloalkyl group which may be substituted and aralkyl group which may be substituted. “n” is a number of replication and represents an integer of 0 to 100.
摘要:
This invention provides for a protein of the TGF-β superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as monomers, display higher bone morphogenetic activity than the wild-type protein dimers. Also provided is a method for producing and isolating these monomers by plasmid driven expression in various host systems including E. coli. In addition, the invention discloses the use of an agent containing purified monomers in preventing and treating diseases and problems affecting bone and/or cartilage.
摘要:
A method of storing a photoreceptor or a process cartridge including the photoreceptor, wherein the photoreceptor or the process cartridge is stored in an environment having a temperature not higher than 23° C. for not less than an year after produced.
摘要:
An endless belt including an endless body having opposite side edges and an interior surface, and a pair of spaced apart parallel guides bonded to the interior surface of the endless body at positions adjacent to the side edges thereof and extending longitudinally along the side edges, wherein each of the guides is made of an elastic material and has inside and/or outside surfaces having specific roughness.
摘要:
A thiol methacrylate or acrylate compound represented by the formula (1) or (2): ##STR1## wherein R.sup.1 is H or CH.sub.3 and X is selected from: ##STR2## wherein R.sup.1 is H or CH.sub.3 and m is an integer of 1 to 4. The thiol methacrylate or acrylate compound gives a resin having a high refractive index, a large Abbe number, and a good hardness and heat resistance, and giving little or no smell at processing.
摘要:
A repeatedly usable electrophotographic photoconductor comprising (a) an electroconductive support, (b) an undercoat layer containing therein at least one salt selected from the group consisting of carboxylates, amino carboxylates, phosphates, polyphosphates, phosphites, phosphate derivatives, borates, sulfates and sulfites, and (c) a photoconductive layer, which layers are successively overlaid on the electroconductive support.
摘要:
A 3-benzazocine compound of the formula: ##SPC1##Wherein R.sub.1, R.sub.3, R.sub.4, R.sub.5 and R.sub.8 are each hydrogen or lower alkyl, R.sub.2 is hydrogen, lower alkyl or phenyl and R.sub.6 and R.sub.7 are each lower alkyl, and its pharmaceutically acceptable acid addition salts, which are useful as analgesics and can be produced by reacting a tetrahydropyridine compound of the formula: ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are each as defined above or its salt with a Lewis acid.