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53 条记录 (耗时 0.037 秒)

    Stent with reduced profile
    41.
    发明授权
    Stent with reduced profile 有权
    支架缩小

    公开(公告)号：US08790388B2

    公开(公告)日：2014-07-29

    申请号：US13410543

    申请日：2012-03-02

    申请人： Timothy J. Mickley

    发明人： Timothy J. Mickley

    IPC分类号： A61F2/06

    CPC分类号： A61F2/958 ,  A61F2002/9583 ,  A61F2250/0039 ,  A61M2025/1004

    摘要： Medical devices, systems, and techniques are described for reducing the profile of a stent. In one example, a stent having a reduced state and an expanded state includes a plurality of interconnected annular rings arranged about a longitudinal axis, each of the plurality of annular bands comprising a plurality of peaks and a plurality of troughs, wherein in the reduced state, at least one of the plurality of peaks of at least one of the plurality of rings is positioned a first distance from the longitudinal axis, another one of the plurality of peaks being positioned a second distance from the longitudinal axis, the first distance being less than the second distance, and wherein in the expanded state, the plurality of peaks of the stent being positioned at substantially the same distance from the longitudinal axis.

    摘要翻译： 描述了用于减小支架轮廓的医疗装置，系统和技术。 在一个示例中，具有减小状态和扩张状态的支架包括围绕纵向轴线布置的多个互连的环形圈，所述多个环形带中的每一个包括多个峰和多个槽，其中处于还原状态 所述多个环中的至少一个环中的至少一个的至少一个峰中的至少一个与所述纵向轴线定位成第一距离，所述多个峰中的另一个位于距所述纵向轴线的第二距离处，所述第一距离较小 并且其中在展开状态下，支架的多个峰位于与纵向轴线基本相同的距离处。

    STENT AND DELIVERY SYSTEM
    42.
    发明申请
    STENT AND DELIVERY SYSTEM 审中-公开
    STENT和交付系统

    公开(公告)号：US20120239128A1

    公开(公告)日：2012-09-20

    申请号：US13240678

    申请日：2011-09-22

    申请人： Brian Tischler ,  James F. Hemerick ,  Daniel Gregorich ,  Michael P. Meyer ,  Timothy J. Mickley ,  Jan Weber ,  Dennis A. Boismier

    发明人： Brian Tischler ,  James F. Hemerick ,  Daniel Gregorich ,  Michael P. Meyer ,  Timothy J. Mickley ,  Jan Weber ,  Dennis A. Boismier

    IPC分类号： A61F2/84 ,  A61F2/82

    CPC分类号： A61F2/91 ,  A61F2/844 ,  A61F2/958 ,  A61F2002/9583 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/006

    摘要： Techniques are disclosed that allow a stent to be folded within a balloon of a stent delivery system. In one example, a stent has first and second columns that extend from a proximal end to a distal end along a longitudinal axis. Each of the first columns extend substantially parallel to the longitudinal axis and comprise a plurality of elements that each have a substantially polygonal shape. Each of the second columns extend substantially parallel to the longitudinal axis and are between adjacent first columns. Each of the respective second columns include a plurality of first connectors that have a curvilinear shape and that extend in a substantially circumferential direction to connect adjacent first columns. The stent also has a plurality of second connectors, wherein at least one of the second connectors extends between a first element and a second element.

    摘要翻译： 公开了允许支架在支架输送系统的球囊内折叠的技术。 在一个示例中，支架具有沿着纵向轴线从近端延伸到远端的第一和第二柱。 每个第一列基本上平行于纵向轴线延伸并且包括多个元件，每个元件具有基本上多边形的形状。 每个第二列基本上平行于纵向轴线延伸并且在相邻的第一列之间。 每个相应的第二列包括多个第一连接器，其具有曲线形状并且沿大致圆周方向延伸以连接相邻的第一列。 支架还具有多个第二连接器，其中至少一个第二连接器在第一元件和第二元件之间延伸。

    Stent with Reduced Profile
    43.
    发明申请
    Stent with Reduced Profile 有权
    支架减少

    公开(公告)号：US20120226342A1

    公开(公告)日：2012-09-06

    申请号：US13410543

    申请日：2012-03-02

    申请人： Timothy J. Mickley

    发明人： Timothy J. Mickley

    IPC分类号： A61F2/84 ,  A61F2/82

    CPC分类号： A61F2/958 ,  A61F2002/9583 ,  A61F2250/0039 ,  A61M2025/1004

    摘要： Medical devices, systems, and techniques are described for reducing the profile of a stent. In one example, a stent having a reduced state and an expanded state includes a plurality of interconnected annular rings arranged about a longitudinal axis, each of the plurality of annular bands comprising a plurality of peaks and a plurality of troughs, wherein in the reduced state, at least one of the plurality of peaks of at least one of the plurality of rings is positioned a first distance from the longitudinal axis, another one of the plurality of peaks being positioned a second distance from the longitudinal axis, the first distance being less than the second distance, and wherein in the expanded state, the plurality of peaks of the stent being positioned at substantially the same distance from the longitudinal axis.

    摘要翻译： 描述了用于减小支架外形的医疗装置，系统和技术。 在一个示例中，具有减小状态和扩张状态的支架包括围绕纵向轴线布置的多个互连的环形圈，所述多个环形带中的每一个包括多个峰和多个槽，其中处于还原状态 所述多个环中的至少一个环中的至少一个的至少一个峰中的至少一个与所述纵向轴线定位成第一距离，所述多个峰中的另一个位于距所述纵向轴线的第二距离处，所述第一距离较小 并且其中在展开状态下，支架的多个峰位于与纵向轴线基本相同的距离处。

    Local delivery of therapeutic agent to heart valves
    44.
    发明授权
    Local delivery of therapeutic agent to heart valves 有权
    局部向心脏瓣膜递送治疗剂

    公开(公告)号：US08038709B2

    公开(公告)日：2011-10-18

    申请号：US12022413

    申请日：2008-01-30

    申请人： Maria Palasis ,  Timothy J. Mickley ,  Toby Freyman ,  Wendy Naimark

    发明人： Maria Palasis ,  Timothy J. Mickley ,  Toby Freyman ,  Wendy Naimark

    IPC分类号： A61F2/06 ,  A61M31/00

    CPC分类号： A61M31/002 ,  A61F2/24 ,  A61F2250/0067

    摘要： The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.

    摘要翻译： 本发明涉及使用这些医疗装置来治疗心脏瓣膜的可植入医疗装置和方法。 在一个实施例中，提供了包括身体的医疗装置。 身体可以具有其一部分，包括治疗剂，并且可被构造成在靠近心脏瓣膜的位置支撑装置。 根据本发明的实施例的方法还可以包括提供具有身体的医疗装置，其中至少一部分包括治疗剂。 这些方法还可以包括将医疗装置定位在靠近心脏瓣膜的下游表面的位置并固定装置。 然后释放的治疗剂可以被递送到心脏瓣膜。

    Repetitive Cell Bifurcation / Side Branch Ostia Support Stent
    45.
    发明申请
    Repetitive Cell Bifurcation / Side Branch Ostia Support Stent 审中-公开
    重复细胞分叉/侧支支气管支架

    公开(公告)号：US20110160840A1

    公开(公告)日：2011-06-30

    申请号：US12964175

    申请日：2010-12-09

    申请人： Michael P. Meyer ,  Alison Julson ,  Timothy J. Mickley

    发明人： Michael P. Meyer ,  Alison Julson ,  Timothy J. Mickley

    IPC分类号： A61F2/82

    CPC分类号： A61F2/856 ,  A61F2/91 ,  A61F2/915

    摘要： A stent comprises at least one closed pathway that defines a single cell. In some embodiments, the closed pathway includes a plurality of petals constructed and arranged to extend away from the tubular wall of the stent. In one embodiment, some of the petals of the closed pathway overlap other of the petals of the closed pathway when the stent is in a reduced state. In at least one embodiment, the stent comprises a plurality of closed pathways. In one embodiment, the closed pathways are arranged in bands that extend either along the length of the stent or about the circumference of the stent.

    摘要翻译： 支架包括限定单个电池的至少一个闭合通路。 在一些实施例中，封闭通路包括构造和布置为远离支架的管状壁延伸的多个花瓣。 在一个实施例中，当支架处于减小状态时，闭合通道的一些花瓣与闭合通路的其他花瓣重叠。 在至少一个实施例中，支架包括多个闭合通路。 在一个实施例中，闭合通道被布置成沿着支架的长度或者围绕支架的圆周延伸的带。

    Variable depth injection device and method
    47.
    发明授权
    Variable depth injection device and method 失效
    可变深度注射装置及方法

    公开(公告)号：US07678077B2

    公开(公告)日：2010-03-16

    申请号：US10781775

    申请日：2004-02-20

    申请人： Chad G. Harris ,  Matthew L. Hawk ,  Timothy J. Mickley

    发明人： Chad G. Harris ,  Matthew L. Hawk ,  Timothy J. Mickley

    IPC分类号： A61M5/00

    CPC分类号： A61M25/0606 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/0084 ,  A61M2025/0089

    摘要： An apparatus for the injection of therapeutic and other agents at a target site within a patient's body. A catheter including a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also including a second elongated shaft slidingly disposed in the first elongated shaft, the second elongated shaft having a distal end and a proximal and a lumen extending therebetween. The catheter further including a third elongated shaft disposed in and attached to the second elongate shaft, the third elongated shaft to move in a one-to-one relationship with the first elongated shaft and the second elongated shaft to maintain a predetermined needle deployment length as each are subjected to various bend configurations.

    摘要翻译： 用于在患者体内的靶位置注射治疗剂和其它药剂的装置。 一种导管，其包括具有远端和近端的第一细长轴和在其间延伸的内腔。 导管还包括滑动地设置在第一细长轴中的第二细长轴，第二细长轴具有远端和近端以及在其间延伸的内腔。 所述导管还包括设置在所述第二细长轴中并连接到所述第二细长轴的第三细长轴，所述第三细长轴与所述第一细长轴和所述第二细长轴以一对一关系移动，以将预定的针展开长度保持为 每个都经受各种弯曲构造。

    Infusion devices and method
    49.
    发明授权
    Infusion devices and method 有权
    输液装置及方法

    公开(公告)号：US06939322B2

    公开(公告)日：2005-09-06

    申请号：US10621378

    申请日：2003-07-18

    申请人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    发明人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    IPC分类号： A61J1/00 ,  A61J1/14 ,  A61M5/46 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M25/098 ,  A61M5/00

    CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

    摘要： Myocardial revascularization catheters and methods are provided herein. Catheters in accord with the present invention may include an outer shaft and an inner shaft where the inner shaft may be slidably and rotatably disposed in the outer shaft and the distal movement of the inner shaft may be arrested by the engagement of stops and catches located within the inner and outer shaft Methods in accord with the current invention may include providing a therapeutic, providing a radiopaque contrast media, injecting the therapeutic through a lumen into the myocardium of the heart, and injecting the radiopaque contrast media through a lumen into myocardium of the heart. In this example, the location of the injection the radiopaque material may be chosen to indicate the injection point of the injection of the therapeutic.

    摘要翻译： 本文提供了心肌血运重建导管和方法。 根据本发明的导管可以包括外轴和内轴，其中内轴可以可滑动地和可旋转地设置在外轴中，并且内轴的远端运动可以通过位于内部的止动件和卡扣的接合来阻止 根据本发明的内外轴方法可以包括提供治疗剂，提供不透射线的造影剂，通过内腔将治疗剂注射到心脏的心肌中，以及将不透射线的造影剂通过内腔注射到心脏的心肌中 心。 在该示例中，可以选择注射不透射线材料的位置以指示治疗剂的注射的注射点。

    Infusion devices and method
    50.
    发明授权
    Infusion devices and method 失效

    公开(公告)号：US06616626B2

    公开(公告)日：2003-09-09

    申请号：US09747157

    申请日：2000-12-21

    申请人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    发明人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    IPC分类号： A61M3100

    CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

    摘要： Devices and methods for performing improved percutaneous myocardial revascularization (PMR) procedures. One device includes a preassembled PMR drug delivery catheter and a drug neutralizing vial. The vial assembly allows prepping the PMR catheter by flushing drug through distal needle, and into a vial cavity where the drug is neutralized by a neutralizing agent. One set of devices includes needles having protrusions secured to the distal regions of drug delivery tubes. One needle has outward protruding barbs engaging the inner tube wall while another needle has outward threads which can screw into the tube inner wall. Radiopaque marker bands are also included in the present invention which are asymmetrically distributed on the catheter shaft, allowing a treating physician to determine under fluoroscopy whether the catheter distal region is pointed away or toward the treating physician, as well as determining whether the catheter distal region is rotated toward or away from the treating physician. PMR devices include catheters having dual injection needles, for both injecting a drug into the heart wall and a radiopaque contrast media to mark the already treated sites. One PMR injection device has multiple stops for allowing controlled, variable needle depth penetration with a single distal needle tip.