公开(公告)号：US5221755A

公开(公告)日：1993-06-22

申请号：US866519

申请日：1992-04-10

申请人： Akio Yamaguchi ,  Yoji Hori ,  Susumu Akutagawa

发明人： Akio Yamaguchi ,  Yoji Hori ,  Susumu Akutagawa

IPC分类号： C07B61/00 ,  C07D321/08 ,  C08G63/08 ,  C08G63/664 ,  C08G63/78

CPC分类号： C07D321/08

摘要： An optically active 7-substituted-1,4-dioxepan-5-one derivative represented by the general formula (I): ##STR1## wherein R represents an alkyl group having from 1 to 5 carbon atoms; and * means an asymmetric carbon atom, is disclosed. An optically active polymer represented by formula (II): ##STR2## wherein R and * are as defined above; and n is an integer of 25 or more, obtained by ring opening polymerization of the optically active 7-substituted-1,4-dioxepan-5-one derivative represented by formula (I) is also disclosed. A process for producing the optically active polymer represented by formula (II) is further disclosed, comprising subjecting an optically active 7-substituted-1,4-dioxepan-5-one derivative represented by formula (I) to ring opening polymerization in the presence of at least one catalyst selected from the group consisting of (i) an organotin compound, (ii) an organoaluminum compound and water, and (iii) an organozinc compound and water.

摘要翻译： 由通式（I）表示的光学活性的7-取代-1,4-二氧杂环庚烯-5-酮衍生物：其中R表示具有1至5个碳原子的烷基; 和*表示不对称碳原子。 由式（II）表示的光学活性聚合物：其中R和*如上所定义; 还公开了通过式（I）表示的光学活性7-取代-1,4-二氧杂环庚烷-5-酮衍生物的开环聚合得到的n为25以上的整数。 进一步公开了制备由式（II）表示的光学活性聚合物的方法，包括使式（I）表示的光学活性7-取代-1,4-二氧杂环庚烷-5-酮衍生物在存在下开环聚合 选自（i）有机锡化合物，（ii）有机铝化合物和水，和（iii）有机锌化合物和水的至少一种催化剂。

公开(公告)号：US09061959B2

公开(公告)日：2015-06-23

申请号：US13990872

申请日：2011-12-01

申请人： Hironori Maeda ,  Hisanori Itoh ,  Shinya Yamada ,  Yoji Hori

发明人： Hironori Maeda ,  Hisanori Itoh ,  Shinya Yamada ,  Yoji Hori

IPC分类号： C07C29/132 ,  C07B53/00 ,  C07C29/17 ,  C07C29/56 ,  B01J31/18 ,  B01J31/26 ,  B01J21/18 ,  B01J23/44

CPC分类号： C07C29/132 ,  B01J21/18 ,  B01J23/44 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/17 ,  C07C29/56 ,  C07C2601/14 ,  C07C35/12 ,  C07C35/17

摘要： An object of the present invention is to provide a method for manufacturing an optically active menthol having fewer steps, which generates less environmentally polluting waste because a catalytic reaction is involved in all of the steps, and is capable of saving a production cost. The present invention relates to a method for manufacturing an optically active menthol, including the following steps: A-1) asymmetrically hydrogenating at least one of geranial and neral to thereby obtain an optically active citronellal, B-1) conducting a ring-closure reaction of the optically active citronellal in the presence of an acid catalyst to thereby obtain an optically active isopulegol, and C-1) hydrogenating the optically active isopulegol to thereby obtain an optically active menthol.

摘要翻译： 本发明的目的是提供一种制造具有较少步骤的光学活性薄荷醇的方法，其由于在所有步骤中都涉及催化反应而产生较少环境污染的废物，并且能够节省生产成本。 本发明涉及一种光学活性薄荷醇的制造方法，其包括以下步骤：A-1）不对称地氢化至少一种香叶酸和盐酸，从而获得光学活性香茅醛B-1，进行闭环反应 的光学活性香茅醛在酸催化剂的存在下反应，从而得到光学活性的异胡列酮，和C-1）氢化光学活性异胡脑酮，从而得到光学活性的薄荷醇。

公开(公告)号：US20050059830A1

公开(公告)日：2005-03-17

申请号：US10899965

申请日：2004-07-26

申请人： Tomoya Sawaki ,  Hiroyuki Kenmochi ,  Yoji Hori

发明人： Tomoya Sawaki ,  Hiroyuki Kenmochi ,  Yoji Hori

IPC分类号： C07D307/93 ,  C07D307/00

CPC分类号： C07D307/00

摘要： An object of the present invention is to provide a novel monomer compound having a lactone structure which gives polymers having more excellent feature as resist material, etc. The present invention relates to a compound represented by the following formula [1]: wherein R1 and R2 are an alkyl group; R3 and R4 are each independently hydrogen atom or an alkyl group; R5 is hydrogen atom, acryloyl group or methacryloyl group; and X is a methylene group which may have an alkyl group or an ethylene group which may have an alkyl group. The present invention provides a compound having a lactone structure which gives a polymer having more excellent feature particularly as a resist material and also provides a hydroxy lactone being useful as a material, etc. therefor.

摘要翻译： 本发明的目的是提供一种具有内酯结构的新单体化合物，其具有作为抗蚀剂材料等具有更优异特征的聚合物。本发明涉及由下式[1]表示的化合物：其中R 1 且R 2为烷基; R 3和R 4各自独立地为氢原子或烷基; R 5是氢原子，丙烯酰基或甲基丙烯酰基; X为可以具有烷基的亚甲基或可具有烷基的亚乙基。 本发明提供了具有内酯结构的化合物，其特别是作为抗蚀剂材料得到具有更优异特征的聚合物，并且还提供可用作材料的羟基内酯等。

公开(公告)号：US06774269B2

公开(公告)日：2004-08-10

申请号：US10045157

申请日：2002-01-15

申请人： Takeshi Iwata ,  Yoshiki Okeda ,  Yoji Hori

发明人： Takeshi Iwata ,  Yoshiki Okeda ,  Yoji Hori

IPC分类号： C07C3508

CPC分类号： C07C29/56 ,  C07C2601/14 ,  C07C35/17

摘要： A process for producing l-isopulegol by simple operations with safety in high yield. A process for producing isopulegol, which comprises selectively cyclizing citronellal in the presence of a tris(2,6-diarylphenoxy)aluminum catalyst represented by the following general formula (3): wherein Al represents an aluminum atom, Ar1 and Ar2 each represent a substituted or unsubstituted aryl group or a heteroaryl group; and R1, R2 and R3 each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atom(s), an alkoxy group having 1 to 8 carbon atom(s), a substituted or unsubstituted aryl group, a dialkylamino group having 1 to 4 carbon atom(s), or a nitro group.

摘要翻译： 通过简单的操作以高产率安全地生产l-异头孢烯的方法。 一种生产异胡醇的方法，其包括在由以下通式（3）表示的三（2,6-二芳基苯氧基）铝催化剂存在下选择性环化香茅醛：其中Al表示铝原子，Ar 1和Ar 2， 2>各自表示取代或未取代的芳基或杂芳基; R 1，R 2和R 3各自表示氢原子，卤素原子，碳原子数为1〜8的烷基，碳原子数1〜8的烷氧基， 取代或未取代的芳基，碳原子数为1〜4的二烷基氨基或硝基。

公开(公告)号：US06489522B2

公开(公告)日：2002-12-03

申请号：US09827334

申请日：2001-04-06

申请人： Shinya Yamada ,  Yoshiki Okeda ,  Yoji Hori ,  Toshimitsu Hagiwara

发明人： Shinya Yamada ,  Yoshiki Okeda ,  Yoji Hori ,  Toshimitsu Hagiwara

IPC分类号： C07C3500

CPC分类号： C07C209/68 ,  C07B2200/07 ,  C07C29/141 ,  C07C33/025 ,  C07C45/42 ,  C07C47/21 ,  C07C211/21

摘要： Provided is citronellol, which has an elegant rosy fragrance and is extremely useful for fragrance impartation to aromatic articles. A mixture of an alkylamine and isoprene in a molar ratio of from 1:4 to 1:4.5 is subjected to telomerization at 80 to 100° C. for 2.5 to 3.5 hours in the presence of an alkyllithium catalyst and/or phenyllithium catalyst to obtain a nerylamine compound containing 2 to 10 wt % &agr;-nerylamine compound represented by general formula (4). From this nerylamine compound, citronellol containing 2 to 10 wt % optically active 3,7-dimethyl-7-octenol is produced through the reaction steps of asymmetric isomerization, hydrolysis, and hydrogenation.

摘要翻译： 提供香茅醇，其具有优雅的玫瑰香，并且对芳香物品的芳香赋予非常有用。 摩尔比为1:4〜1:4.5的烷基胺和异戊二烯的混合物在烷基锂催化剂和/或苯基锂催化剂存在下，在80〜100℃下进行2.5〜3.5小时的调聚，得到 含有通式（4）表示的2-10重量％α-椰子胺化合物的橙花胺化合物。由该橙花胺化合物，通过反应步骤产生含有2至10重量％光学活性的3,7-二甲基-7-辛烯醇的香茅醇 的不对称异构化，水解和氢化。

公开(公告)号：US06420027B2

公开(公告)日：2002-07-16

申请号：US09781160

申请日：2001-02-13

申请人： Yoshiharu Kimura ,  Yoji Hori

发明人： Yoshiharu Kimura ,  Yoji Hori

IPC分类号： D01F800

CPC分类号： D01F8/14 ,  Y10T428/2924 ,  Y10T428/2929 ,  Y10T428/2931

摘要： A biodegradable complex fiber which retains excellent biodegradability and hydrolyzability and has high strength and high melting temperature suitable for practical use and a method for producing the biodegradable complex fiber are provided. The biodegradable complex fiber comprises at least one polymer material selected from the group consisting of a polyglycolic acid, a poly(glycolic acid-co-lactic acid) and polylactic acid as a core component or as a shell component and a polymer material of poly(3-hydroxybutyric acid) groups or a polymer material of an aliphatic polyester consisting of a dibasic acid and a diol as a shell component or as a core component. The method comprises producing the biodegradable complex fiber by melt spinning.

摘要翻译： 提供了保持优异的生物降解性和水解性并且具有适用于实际应用的高强度和高熔融温度的可生物降解的复合纤维以及生产可生物降解的复合纤维的制造方法。 可生物降解的复合纤维包含至少一种选自聚乙醇酸，聚（乙醇酸 - 共乳酸）和聚乳酸作为核心组分或作为壳组分的聚合物材料和聚 3-羟基丁酸）基团或由二元酸和二醇作为壳组分或作为核心组分的脂肪族聚酯的聚合物材料。 该方法包括通过熔融纺丝生产可生物降解的复合纤维。

公开(公告)号：US6121343A

公开(公告)日：2000-09-19

申请号：US162506

申请日：1998-09-29

申请人： Hideyuki Hongo ,  Yoji Hori ,  Yasuo Fujiwara ,  Seiichi Abe ,  Minoru Hanada

发明人： Hideyuki Hongo ,  Yoji Hori ,  Yasuo Fujiwara ,  Seiichi Abe ,  Minoru Hanada

IPC分类号： A61K8/00 ,  A61K8/85 ,  A61K8/90 ,  A61K31/765 ,  A61Q13/00 ,  C08L67/04 ,  C08L101/16 ,  C11B9/00

CPC分类号： A61K8/85 ,  A61Q13/00 ,  A61K2800/56

摘要： A perfume-containing controlled release biodegradable resin composition which can release aroma of the included perfume gradually without changing its perfume tone and can be used in such applications as deodorants, etc. The resin composition includes a biodegradable resin which is a random or block copolymer polyester represented by the following formula (1): ##STR1## wherein R.sup.1 is a hydrocarbon radical having 1 to 15 carbon atoms, which is a divalent organic group that may be have a double bond or an oxygen atom but does not have a group represented by the formula ##STR2## wherein the symbol "*" is an asymmetric carbon atom. Each of m and n is 0 or an integer of 100 to 9,000, provided that m+n is within the range of 200 to 10,000. The molar ratio of the structural units [I] and [II] is 1-99:99-1 when m and n are not 0 and the number average molecular weight is 5,000 to 1,000,000, and a perfume such as a cyclic ether, a natural plant perfume, etc., is held in the biodegradable resin.

摘要翻译： 一种含香料的控释生物降解性树脂组合物，其可以逐渐释放所含香料的香味，而不改变其香料色调，并且可用于除臭剂等的应用中。树脂组合物包括可生物降解的树脂，其是无规或嵌段共聚物聚酯 由下式（1）表示：其中R 1是具有1至15个碳原子的烃基，其是可以具有双键或氧原子但不具有由下式表示的基团的二价有机基团：其中 符号“*”是不对称碳原子。 m和n分别为0或100〜9000的整数，条件是m + n在200〜10000的范围内。 当m和n不为0且数均分子量为5,000至1,000,000时，结构单元[I]和[II]的摩尔比为1-99:99-1，环状醚， 天然植物香料等保存在可生物降解的树脂中。

公开(公告)号：US5981782A

公开(公告)日：1999-11-09

申请号：US963619

申请日：1997-11-04

申请人： Yoshiki Okeda ,  Yoji Hori ,  Toshimitsu Hagiwara

发明人： Yoshiki Okeda ,  Yoji Hori ,  Toshimitsu Hagiwara

IPC分类号： C07D305/12 ,  B01J31/24 ,  C07B53/00 ,  C07B61/00 ,  C07D315/00 ,  C07F15/00

CPC分类号： B01J31/2452 ,  C07D315/00 ,  C07F15/0053 ,  B01J2231/645 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J31/2208 ,  B01J31/2295 ,  C07B2200/07

摘要： The present invention provides a catalyst which exhibits a high catalytic activity and allows asymmetric reaction in a high asymmetric yield to obtain a reaction product having a high optical purity. The present invention also provides a process for the preparation of an optically active 4-methyl-2-oxetanone having a high optical purity useful as starting material of polymer in a high yield in a short period in the presence of the foregoing catalyst. A novel ruthenium-iodo-optically active phosphine complex is provided, represented by the following general formula (1):Ru--I.sub.2 --(R.sup.1 -BINAP) (1)wherein R.sup.1 -BINAP represents an optically active tertiary phosphine represented by the following general formula (2): ##STR1## wherein R.sup.1 represents an aryl group which may have a substituent selected from the group consisting of a C.sub.1-4 lower alkyl group, a C.sub.1-4 lower alkoxy group, a C.sub.1-4 lower alkylamino group, and a halogen atom or a C.sub.3-8 cycloalkyl group.

摘要翻译： 本发明提供一种催化活性高的催化剂，能够以不对称产率进行不对称反应，得到光学纯度高的反应产物。 本发明还提供了在上述催化剂存在下，在短时间内以高收率制备具有高光学纯度的光学纯度高的光学活性4-甲基-2-氧杂环丁酮的方法。 提供了由以下通式（1）表示的新型钌 - 碘 - 光学活性膦配合物：Ru-I2-（R1-BINAP）（1）其中R1-BINAP表示由以下通式表示的光学活性叔膦 式（2）：其中R1表示可以具有选自C 1-4低级烷基，C 1-4低级烷氧基，C 1-4低级烷基氨基和卤素原子的取代基的芳基 或C 3-8环烷基。

公开(公告)号：US5840811A

公开(公告)日：1998-11-24

申请号：US786253

申请日：1997-01-22

申请人： Yoji Hori ,  Tohru Kobayashi ,  Hideyuki Hongo ,  Akio Yamaguchi ,  Yoko Takahashi ,  Takashi Imai ,  Toshimitsu Hagiwara

发明人： Yoji Hori ,  Tohru Kobayashi ,  Hideyuki Hongo ,  Akio Yamaguchi ,  Yoko Takahashi ,  Takashi Imai ,  Toshimitsu Hagiwara

IPC分类号： C08G63/06 ,  C08G63/08 ,  C08G63/82 ,  C08L101/16 ,  C08G63/85

CPC分类号： C08G63/823 ,  C08G63/08

摘要： An optically active block polyester copolymer formed of structural units represented by the following general formulas (I) and (II): ##STR1## wherein represents for an asymmetric carbon atom and m and n each represents a natural number in the range of from 300 to 5000 is obtained by subjecting an optically active butyrolactone and a species of lactone other than the optically active butyrolactone to sequential ringopening copolymerization in the presence of a catalyst. This optically active block polyester copolymer possesses a high molecular weight and a high melting point (not less than 130.degree. C.) and forms a biodegradable and hydrolyzable material of high strength capable of tolerating the impacts of actual use.

摘要翻译： 由以下通式（I）和（II）表示的结构单元形成的光学活性嵌段聚酯共聚物：式（I）公制碳原子，m和n各自表示300-5000的自然数 是通过使光学活性丁内酯和除光学活性丁内酯以外的其他种类的内酯在催化剂存在下进行顺序环环化共聚获得的。 该光学活性嵌段聚酯共聚物具有高分子量和高熔点（不低于130℃），并形成能够耐受实际影响的高强度的可生物降解和可水解的材料。

公开(公告)号：US5824751A

公开(公告)日：1998-10-20

申请号：US592518

申请日：1996-01-26

申请人： Yoji Hori ,  Yoko Takahashi ,  Hideyuki Hongo ,  Akio Yamaguchi ,  Toshimitsu Hagiwara

发明人： Yoji Hori ,  Yoko Takahashi ,  Hideyuki Hongo ,  Akio Yamaguchi ,  Toshimitsu Hagiwara

IPC分类号： C08G63/06 ,  C08G63/08 ,  C08G63/64

CPC分类号： C08G63/08 ,  C08G63/06 ,  C08G63/64

摘要： The biodegradable composition comprises at least poly(beta-hydroxybutyric acid) or a biodegradable copolymer thereof and a stereospecifically regular block copolymer having the structure units of formula (I): ##STR1## where R1 is a hydrocarbon group having 1 to 14 carbon atoms, optionally including double bonds, oxygen atoms or both of them; and m and n are respectively an integer ranging from 300 to 5,000, or having the structure units of formula (II): ##STR2## where R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are either a hydrogen atom or a methyl group; and m and n are respectively an integer ranging from 300 to 5,000.

摘要翻译： 可生物降解组合物至少包含聚（β-羟基丁酸）或其可生物降解的共聚物和具有式（I）结构单元的立体专一规则嵌段共聚物：其中R 1为具有1至14个碳原子的烃基 碳原子，任选地包括双键，氧原子或它们两者; m和n分别为300-5000的整数，或具有式（II）的结构单元：其中R 2，R 3，R 4和R 5为氢原子或甲基; m和n分别为300-5000的整数。