公开(公告)号：US07098255B2

公开(公告)日：2006-08-29

申请号：US10881756

申请日：2004-06-30

申请人： Hiroshi Seyanagi ,  Kaoru Inoue ,  Kazuyuki Ogawa ,  Takashi Masui ,  Koichi Ono

发明人： Hiroshi Seyanagi ,  Kaoru Inoue ,  Kazuyuki Ogawa ,  Takashi Masui ,  Koichi Ono

IPC分类号： C08G18/28

CPC分类号： C08J9/30 ,  B24B37/24 ,  B24D3/28 ,  C08J9/0061 ,  C08J2375/04 ,  C08J2483/00

摘要： A process for producing a finely cellular polyurethane foam by mixing a first ingredient comprising an isocyanate compound and a second ingredient comprising a compound containing an active hydrogen group, characterized by comprising adding a nonionic silicone surfactant containing no hydroxyl group to at least one of the first ingredient and the second ingredient in an amount of 0.1 to 5 wt %, excluding 5 wt %, based on the total amount of the first ingredient and the second ingredient, subsequently agitating the surfactant containing ingredient together with an unreactive gas, which has no reactivity to isocyanate group or active hydrogen group, to disperse the unreactive gas as fine bubbles to prepare a bubble dispersion and then mixing the bubble dispersion with the remaining ingredient to cure the resultant mixture and forming finely cellular structure into the resultant polyurethane foam by the fine bubbles of the bubble dispersion.

摘要翻译： 一种通过混合包含异氰酸酯化合物的第一成分和包含含有活性氢基团的化合物的第二成分来生产细孔聚氨酯泡沫体的方法，其特征在于将不含羟基的非离子硅氧烷表面活性剂加入到第一 成分和第二成分的量为0.1至5重量％，不包括5重量％，基于第一成分和第二成分的总量，随后将表面活性剂含量与不起反应性的非反应性气体一起搅拌 异氰酸酯基或活性氢基团，将非活性气体分散为细小气泡以制备气泡分散体，然后将气泡分散体与剩余的组分混合，以使所得混合物固化，并通过微小气泡形成细小结构的聚氨酯泡沫体 的气泡分散。

公开(公告)号：US20060037699A1

公开(公告)日：2006-02-23

申请号：US10536621

申请日：2003-11-27

申请人： Masahiko Nakamori ,  Tetsuo Shimomura ,  Takatoshi Yamada ,  Kazuyuki Ogawa ,  Atsushi Kazuno ,  Kimihiro Watanabe

发明人： Masahiko Nakamori ,  Tetsuo Shimomura ,  Takatoshi Yamada ,  Kazuyuki Ogawa ,  Atsushi Kazuno ,  Kimihiro Watanabe

IPC分类号： C23F1/00

CPC分类号： B24B37/205 ,  B24B37/013

摘要： A polishing pad enabling a highly precise optical endpoint sensing during the polishing process and thus having excellent polishing characteristics (such as surface uniformity and in-plane uniformity) is disclosed. A polishing pad enabling to obtain the polishing profile of a large area of a wafer is also disclosed. A polishing pad of a first invention comprises a light-transmitting region having a transmittance of not less than 50% over the wavelength range of 400 to 700 nm. A polishing pad of a second invention comprises a light-transmitting region having a thickness of 0.5 to 4 mm and a transmittance of not less than 80% over the wavelength range of 600 to 700 nm. A polishing pad of a third invention comprises a light-transmitting region arranged between the central portion and the peripheral portion of the polishing pad and having a length (D) in the diametrical direction which is three times or more longer than the length (L) in the circumferential direction.

摘要翻译： 公开了一种抛光垫，其能够在抛光过程中进行高精度的光学终点感测，因此具有优异的抛光特性（例如表面均匀性和面内均匀性）。 还公开了能够获得大面积晶片的抛光轮廓的抛光垫。 第一发明的抛光垫包括在400〜700nm的波长范围内具有不小于50％透射率的透光区域。 第二发明的抛光垫包括在600至700nm的波长范围内具有0.5至4mm厚度的透光区域和不小于80％的透光率。 第三发明的抛光垫包括布置在抛光垫的中心部分和周边部分之间的透光区域，其沿直径方向的长度（D）比长度（L）长三倍或更长， 在圆周方向。

公开(公告)号：US06777455B2

公开(公告)日：2004-08-17

申请号：US10111738

申请日：2002-04-25

申请人： Hiroshi Seyanagi ,  Kaoru Inoue ,  Kazuyuki Ogawa ,  Takashi Masui ,  Koichi Ono

发明人： Hiroshi Seyanagi ,  Kaoru Inoue ,  Kazuyuki Ogawa ,  Takashi Masui ,  Koichi Ono

IPC分类号： C08J900

CPC分类号： C08J9/30 ,  B24B37/24 ,  B24D3/28 ,  C08J9/0061 ,  C08J2375/04 ,  C08J2483/00

摘要： A process for producing a finely cellular polyurethane foam by mixing a first ingredient comprising an isocyanate compound and a second ingredient comprising a compound containing an active hydrogen group, characterized by comprising adding a nonionic silicone surfactant containing no hydroxyl group to at least one of the first ingredient and the second ingredient in an amount of 0.1 to 5 wt %, excluding 5 wt %, based on the total amount of the first ingredient and the second ingredient, subsequently agitating the surfactant containing ingredient together with an unreactive gas, which has no reactivity to isocyanate group or active hydrogen group, to disperse the unreactive gas as fine bubbles to prepare a bubble dispersion and then mixing the bubble dispersion with the remaining ingredient to cure the resultant mixture and forming finely cellular structure into the resultant polyurethane foam by the fine bubbles of the bubble dispersion.

公开(公告)号：US5962319A

公开(公告)日：1999-10-05

申请号：US869793

申请日：1997-06-05

申请人： Kazuyuki Ogawa ,  Kazuya Tanaka ,  Kinya Nagata ,  Shoichi Takano

发明人： Kazuyuki Ogawa ,  Kazuya Tanaka ,  Kinya Nagata ,  Shoichi Takano

IPC分类号： C07K14/47 ,  C12N15/12 ,  C12N5/10

CPC分类号： C07K14/47

摘要： An element for specifying the condition and type of immune-related diseases on the basis of the knowledge about the polarization of distribution of Th1/Th2 subsets of helper T cells. The element for specifying or correcting the polarization of the Th1/Th2 subsets is implemented by use of a recombinant vector, a transformant, a human-Th1-specific protein, and an antibody which uses the human-Th1-specific protein as an antigen. A human-Th1-specific gene is prepared and specified by a subtraction technique and is incorporated into the recombinant vector. The transformant is formed by transforming the recombinant vector. The Th1-specific protein is encoded by the gene derived from the transformant.

摘要翻译： 根据关于辅助T细胞Th1 / Th2亚型分布极化的知识，指定免疫相关疾病的病情和类型的要素。 通过使用重组载体，转化体，人Th1特异性蛋白质和使用人Th1特异性蛋白质作为抗原的抗体来实现用于指定或校正Th1 / Th2子集的极化的元件。 制备人Th1特异性基因并通过减法技术规定并且并入重组载体中。 通过转化重组载体形成转化体。 Th1特异性蛋白质由转化体衍生的基因编码。

公开(公告)号：US5506892A

公开(公告)日：1996-04-09

申请号：US214429

申请日：1994-03-18

申请人： Takashi Kojima ,  Kazuyuki Ogawa

发明人： Takashi Kojima ,  Kazuyuki Ogawa

IPC分类号： H04M11/00 ,  H04N5/765 ,  H04N17/06 ,  H04Q9/00

CPC分类号： H04N5/765 ,  H04N17/06

摘要： In order to achieve check and adjustment of electronic apparatus such as a VTR from a remote location, a tone dialer in a service company converts commands and data into tone signals for checking and adjusting a VTR in a user's house, which tone signals are transmitted by a telephone over a telephone line and input to a telephone in the user's house. The tone signals received by the user's telephone are converted into the commands and data by a gateway and input to the VTR.

摘要翻译： 为了实现从远程位置的VTR等电子设备的检查和调整，服务公司中的音调拨号器将命令和数据转换为用于检查和调整用户住宅中的VTR的音频信号，这些音调信号由 电话通过电话线输入用户家中的电话。 由用户电话接收的音调信号由网关转换成命令和数据，并输入到VTR。

公开(公告)号：US08779020B2

公开(公告)日：2014-07-15

申请号：US13607125

申请日：2012-09-07

申请人： Atsushi Kazuno ,  Kazuyuki Ogawa ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Tetsuo Shimomura

发明人： Atsushi Kazuno ,  Kazuyuki Ogawa ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Tetsuo Shimomura

IPC分类号： C08G18/10

CPC分类号： B24B37/24 ,  B24D3/28 ,  B24D3/32 ,  C08G18/12 ,  C08G18/4238 ,  C08G18/4854 ,  C08G18/724 ,  C08G18/758 ,  C08G18/7621 ,  C08G2101/0025 ,  C08G2101/0066 ,  C08J9/30 ,  C08J2375/08 ,  C08G18/3814 ,  C08G18/48 ,  C08G18/3865

摘要： A polishing pad generates very few scratches on a surface of a polishing object, and is excellent in planarization property. The polishing pad has a high polishing rate and is excellent in planarization property. The polishing pad grooves become very little clogged with abrasive grains or polishing swarf during polishing and, even when continuously used for a long period of time, the polishing rate is scarcely reduced.

摘要翻译： 抛光垫在抛光对象的表面上产生很少的划痕，并且平坦化性能优异。 抛光垫具有高的抛光速率，并且平坦化性能优异。 抛光垫槽在抛光过程中变得很少被磨粒或抛​​光屑堵塞，并且即使长时间连续使用，抛光速率也几乎不降低。

公开(公告)号：US08304467B2

公开(公告)日：2012-11-06

申请号：US11914547

申请日：2006-05-10

申请人： Atsushi Kazuno ,  Kazuyuki Ogawa ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Tetsuo Shimomura

发明人： Atsushi Kazuno ,  Kazuyuki Ogawa ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Tetsuo Shimomura

IPC分类号： C08G18/28

CPC分类号： B24B37/24 ,  B24D3/28 ,  B24D3/32 ,  C08G18/12 ,  C08G18/4238 ,  C08G18/4854 ,  C08G18/724 ,  C08G18/758 ,  C08G18/7621 ,  C08G2101/0025 ,  C08G2101/0066 ,  C08J9/30 ,  C08J2375/08 ,  C08G18/3814 ,  C08G18/48 ,  C08G18/3865

摘要： A polishing pad generates very few scratches on a surface of a polishing object, and is excellent in planarization property. The polishing pad has a high polishing rate and is excellent in planarization property. The polishing pad grooves become very little clogged with abrasive grains or polishing swarf during polishing and, even when continuously used for a long period of time, the polishing rate is scarcely reduced.

摘要翻译： 抛光垫在抛光对象的表面上产生很少的划痕，并且平坦化性能优异。 抛光垫具有高的抛光速率，并且平坦化性能优异。 抛光垫槽在抛光过程中变得很少被磨粒或抛​​光屑堵塞，并且即使长时间连续使用，抛光速率几乎不降低。

公开(公告)号：US08288509B2

公开(公告)日：2012-10-16

申请号：US12386974

申请日：2009-04-24

申请人： Masaji Okada ,  Yasushi Takamori ,  Kazuyuki Ogawa ,  Kinya Nagata

发明人： Masaji Okada ,  Yasushi Takamori ,  Kazuyuki Ogawa ,  Kinya Nagata

IPC分类号： A61K39/00 ,  A61K39/38 ,  A61K38/00 ,  C07K16/00 ,  C07K17/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/00

CPC分类号： A61K38/20 ,  A61K38/164 ,  A61K38/1709 ,  A61K38/1729 ,  A61K38/204 ,  A61K38/208 ,  A61K39/04 ,  A61K2300/00

摘要： (Problems)To provide a therapeutic agent for infections comprising granulysin as an active ingredient which has little side effect and no cytotoxicity and to which bacteria can hardly acquire resistance, and a treatment method using the same.(Means for Solving Problems)The present invention provides a therapeutic agent for infections comprising as active ingredient: 15K granulysin, a combination of 15K granulysin and 15K granulysin in vivo expression vector, a combination of 15K granulysin and at least one interleukin selected from IL-6, IL-23 or IL-27, a combination of 15K granulysin in vivo expression vector and at least one interleukin selected from IL-6, IL-23 or IL-27, or a combination of 15K granulysin in vivo expression vector and HSP65DNA and IL-12DNA in vivo expression vector, which enhances killing effects on bacteria and has less side effect, and to which bacteria can hardly acquire resistance, and a treatment method using the same.

摘要翻译： （问题）为了提供包含颗粒溶素作为活性成分的感染治疗剂，其副作用小，无细胞毒性，细菌几乎不能获得抗性，以及使用该治疗剂的治疗方法。 （解决问题的手段）本发明提供一种感染治疗剂，其包含15K颗粒溶素，15K颗粒溶素和15K颗粒溶素在体内表达载体的组合，15K颗粒溶素与至少一种选自IL- 6，IL-23或IL-27，15K颗粒溶素在体内表达载体和选自IL-6，IL-23或IL-27中的至少一种白介素或15K颗粒溶素的体内表达载体和HSP65DNA的组合的组合 和IL-12DNA体内表达载体，其对细菌的杀伤作用增强，副作用较小，细菌几乎不能获得抗性，以及使用其的处理方法。

公开(公告)号：US20090274651A1

公开(公告)日：2009-11-05

申请号：US12386974

申请日：2009-04-24

申请人： Masaji Okada ,  Yasushi Takamori ,  Kazuyuki Ogawa ,  Kinya Nagata

发明人： Masaji Okada ,  Yasushi Takamori ,  Kazuyuki Ogawa ,  Kinya Nagata

IPC分类号： A61K38/20 ,  C07K14/47 ,  A61K38/16 ,  A61K31/711 ,  A61P31/06

CPC分类号： A61K38/20 ,  A61K38/164 ,  A61K38/1709 ,  A61K38/1729 ,  A61K38/204 ,  A61K38/208 ,  A61K39/04 ,  A61K2300/00

摘要： (Problems) To provide a therapeutic agent for infections comprising granulysin as an active ingredient which has little side effect and no cytotoxicity and to which bacteria can hardly acquire resistance, and a treatment method using the same. (Means for Solving Problems) The present invention provides a therapeutic agent for infections comprising as active ingredient: 15K granulysin, a combination of 15K granulysin and 15K granulysin in vivo expression vector, a combination of 15K granulysin and at least one interleukin selected from IL-6, IL-23 or IL-27, a combination of 15K granulysin in vivo expression vector and at least one interleukin selected from IL-6, IL-23 or IL-27, or a combination of 15K granulysin in vivo expression vector and HSP65DNA and IL-12DNA in vivo expression vector, which enhances killing effects on bacteria and has less side effect, and to which bacteria can hardly acquire resistance, and a treatment method using the same.

摘要翻译： （问题）为了提供包含颗粒溶素作为活性成分的感染治疗剂，其副作用小，无细胞毒性，细菌几乎不能获得抗性，以及使用该治疗剂的治疗方法。 （解决问题的手段）本发明提供一种感染治疗剂，其包含15K颗粒溶素，15K颗粒溶素和15K颗粒溶素在体内表达载体的组合，15K颗粒溶素与至少一种选自IL- 6，IL-23或IL-27，15K颗粒溶素在体内表达载体和选自IL-6，IL-23或IL-27中的至少一种白介素或15K颗粒溶素的体内表达载体和HSP65DNA的组合的组合 和IL-12DNA体内表达载体，其对细菌的杀伤作用增强，副作用较小，细菌几乎不能获得抗性，以及使用其的处理方法。

公开(公告)号：US07488236B2

公开(公告)日：2009-02-10

申请号：US11466909

申请日：2006-08-24

申请人： Tetsuo Shimomura ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Shigeru Komai ,  Koichi Ono ,  Kazuyuki Ogawa ,  Atsushi Kazuno ,  Tsuyoshi Kimura

发明人： Tetsuo Shimomura ,  Masahiko Nakamori ,  Takatoshi Yamada ,  Shigeru Komai ,  Koichi Ono ,  Kazuyuki Ogawa ,  Atsushi Kazuno ,  Tsuyoshi Kimura

IPC分类号： B24B7/22

CPC分类号： C08G18/00 ,  B24B37/24 ,  B24D3/30 ,  B24D18/00 ,  C08G18/10 ,  C08G18/12 ,  C08G18/4211 ,  C08G18/4236 ,  C08G18/4808 ,  C08G18/4854 ,  C08G18/61 ,  C08G18/664 ,  C08G18/6674 ,  C08G18/724 ,  C08G2101/00 ,  C08G2101/0066 ,  C08J9/0061 ,  C08J2205/052 ,  C08J2375/04 ,  C08J2483/00 ,  C08L83/00 ,  C09D175/08 ,  H01L21/30625 ,  Y10T428/249953 ,  Y10T428/249976 ,  C08G18/3814 ,  C08G18/3243 ,  C08G18/5096

摘要： The invention provides a polishing pad by which optical materials such as lenses, reflecting mirrors etc., or materials requiring a high degree of surface planarity, as in the polishing of silicone wafers, glass substrates or aluminum substrates for hard disks, or general metal polishing, can be flattened with stability and high polishing efficiency. The invention also provides a polishing pad for semiconductor wafers, which is superior in planarizing characteristic, is free from scratches and can be produced at low cost. There is provided a polishing pad which is free from dechucking error so that neither damage to wafers nor decrease in operating efficiency occurs. There is provided a polishing pad which is satisfactory in planarity, within wafer uniformity, and polishing rate and produces less change in polishing rate. There is provided a polishing pad which can make planarity improvement and scratch decrease compatible.

摘要翻译： 本发明提供了抛光垫，通过该抛光垫，诸如透镜，反射镜等的光学材料或需要高度表面平坦度的材料，如在硅树脂晶片，玻璃基板或用于硬盘的铝基板的抛光中，或通常的金属抛光 ，可平坦化，抛光效率高。 本发明还提供一种平面化特性优异的半导体晶片用抛光垫，无磨损，可以低成本地制造。 提供了没有脱扣误差的抛光垫，从而不会损坏晶片，也不会降低工作效率。 提供了平面性良好，晶片均匀性和抛光速度均匀且抛光速度变化小的抛光垫。 提供了可以使平面性改善和划痕减少兼容的抛光垫。