公开(公告)号：US07405822B2

公开(公告)日：2008-07-29

申请号：US11584020

申请日：2006-10-20

申请人： Zhiyong Li ,  Wei Wu ,  Shih-Yuan Wang

发明人： Zhiyong Li ,  Wei Wu ,  Shih-Yuan Wang

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01J3/44 ,  G01N21/658

摘要： Raman spectroscopy systems include an analyte, a radiation source configured to emit incident radiation having a wavelength, and a detector that is capable of detecting only radiation having wavelengths within a detectable range that includes at least one wavelength corresponding to hyper Raman scattered radiation scattered by the analyte. The wavelength of the incident radiation is outside the detectable range. In particular systems, all wavelengths of radiation that are scattered in the direction of the detector impinge on the detector. Raman spectroscopy methods include providing an analyte and irradiating the analyte with incident radiation having a wavelength, providing a detector capable of detecting only wavelengths of radiation within a detectable range that does not include the wavelength of the incident radiation, and detecting Raman scattered radiation scattered by the analyte. A continuous path free of radiation filters may be provided between the analyte and the detector.

摘要翻译： 拉曼光谱系统包括分析物，被配置为发射具有波长的入射辐射的辐射源，以及检测器，其能够仅检测波长在可检测范围内的辐射，所述波长包括对应于由所述波长散射的超拉曼散射辐射的至少一个波长 分析物。 入射辐射的波长在可检测范围之外。 在特定系统中，在检测器的方向上散射的所有辐射波长都照射在检测器上。 拉曼光谱方法包括提供分析物并用具有波长的入射辐射照射分析物，提供检测器，该检测器仅能够检测不包括入射辐射波长的可检测范围内的辐射波长，并且检测散射的拉曼散射辐射 分析物。 可以在分析物和检测器之间提供不含辐射过滤器的连续路径。

公开(公告)号：US07385691B2

公开(公告)日：2008-06-10

申请号：US11044676

申请日：2005-01-27

申请人： M. Saif Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Stanley Williams

发明人： M. Saif Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Stanley Williams

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01N21/658 ,  G01J3/44 ,  H01L31/02325 ,  H01L31/105

摘要： Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device for performing Raman spectroscopy comprises a substrate and a laser source disposed on the substrate. The laser source may be configured for emanating a laser radiation, which may irradiate an analyte disposed on a Raman enhancement structure. The Raman enhancement structure may be disposed on the substrate or apart from the substrate. The molecular analysis device also include a radiation receiver disposed on the substrate and configured for receiving a Raman scattered radiation, which may be generated by the irradiation of the analyte and Raman enhancement structure.

摘要翻译： 公开了用于增强拉曼光谱和超拉曼的装置，系统和方法。 用于执行拉曼光谱的分子分析装置包括设置在基板上的基板和激光源。 激光源可以被配置为发射激光辐射，其可照射设置在拉曼增强结构上的分析物。 拉曼增强结构可以设置在基板上或者离开基板。 分子分析装置还包括设置在基板上并被配置为用于接收可以通过分析物的照射和拉曼增强结构产生的拉曼散射辐射的辐射接收器。

公开(公告)号：US07307719B2

公开(公告)日：2007-12-11

申请号：US10941714

申请日：2004-09-14

申请人： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

IPC分类号： G01J3/44 ,  G01J3/45

CPC分类号： G01N21/658 ,  G01J3/26

摘要： Wavelength-tunable radiation amplifying structures for Raman spectroscopy are disclosed that include resonant cavities having Raman signal-enhancing structures disposed therein. Systems that include the amplifying structures and methods of performing spectroscopic analysis using the structures and systems are also disclosed.

摘要翻译： 公开了用于拉曼光谱的波长可调辐射放大结构，其包括其中布置有拉曼信号增强结构的谐振腔。 还公开了包括放大结构的系统和使用该结构和系统进行光谱分析的方法。

公开(公告)号：US20070122313A1

公开(公告)日：2007-05-31

申请号：US11291019

申请日：2005-11-30

申请人： Zhiyong Li ,  M. Islam ,  Shih-Yuan Wang

发明人： Zhiyong Li ,  M. Islam ,  Shih-Yuan Wang

IPC分类号： B01L3/00

CPC分类号： B81C1/00071 ,  B01L3/5027 ,  B01L2300/0896

摘要： A nanochannel apparatus and method of fabrication provide an array of nanochannels with distal open or exposed ends formed in situ through a permanent support. A nanofluidic system includes the nanochannel apparatus, a fluidic interface, and a component interfaced to the nanochannel apparatus. The method includes encasing an array of nanowires in a support, and forming the array of nanochannels in situ in locations of the nanowires, such that distal ends of the nanochannels are exposed.

摘要翻译： 纳米通道装置和制造方法提供具有通过永久支撑原位形成的远端开放或暴露端的纳米通道阵列。 纳米流体系统包括纳米通道装置，流体界面和与纳米通道装置相连接的部件。 该方法包括将纳米线阵列包围在支撑体中，并且在纳米线的位置上原位形成纳米通道阵列，使得纳米通道的远端被暴露。

公开(公告)号：US20060275778A1

公开(公告)日：2006-12-07

申请号：US11144586

申请日：2005-06-03

申请人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Philip Kuekes

发明人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Philip Kuekes

IPC分类号： C12Q1/68 ,  C12M1/34

CPC分类号： G01N33/48721 ,  B82Y5/00 ,  B82Y10/00 ,  G01N27/414

摘要： Devices and methods for detecting the constituent parts of biological polymers are disclosed. A molecular analysis device comprises a molecule sensor and a molecule guide. The molecule sensor comprises a single electron transistor including a first terminal, a second terminal, and a nanogap or at least one quantum dot positioned between the first terminal and the second terminal. A nitrogenous material disposed on the at least one quantum dot is configured for an interaction with an identifiable configuration of a molecule. The molecule sensor develops an electronic effect responsive to the interaction. The molecule guide is configured for guiding at least a portion of the molecule substantially near the molecule sensor to enable the interaction.

摘要翻译： 公开了用于检测生物聚合物的组成部分的装置和方法。 分子分析装置包括分子传感器和分子引导件。 分子传感器包括单电子晶体管，其包括位于第一端子和第二端子之间的第一端子，第二端子和纳米隙隙或至少一个量子点。 设置在至少一个量子点上的含氮材料被配置用于与分子的可识别构型的相互作用。 分子传感器产生响应于相互作用的电子效应。 分子引导件被配置用于基本上在分子传感器附近引导分子的至少一部分，以实现相互作用。

公开(公告)号：US20060244568A1

公开(公告)日：2006-11-02

申请号：US11117976

申请日：2005-04-29

申请人： William Tong ,  Geoffrey Lyon ,  Philip Kuekes ,  Zhiyong Li ,  S. Wang ,  R. Williams

发明人： William Tong ,  Geoffrey Lyon ,  Philip Kuekes ,  Zhiyong Li ,  S. Wang ,  R. Williams

IPC分类号： H04Q5/22

CPC分类号： G01D21/00 ,  H04Q9/00

摘要： An assembly for monitoring an environment includes a RFID tag and a sensing unit. The sensing unit is configured to be activated by a RF signal received by the RFID tag and to sense information regarding an environment.

摘要翻译： 用于监测环境的组件包括RFID标签和感测单元。 感测单元被配置为由RFID标签接收的RF信号激活并且感测关于环境的信息。

公开(公告)号：US20050164412A1

公开(公告)日：2005-07-28

申请号：US10995608

申请日：2004-11-22

申请人： Patricia Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

发明人： Patricia Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

IPC分类号： H01L21/28 ,  G11C13/02 ,  H01L21/285 ,  H01L27/28 ,  H01L29/06 ,  H01L21/00

CPC分类号： H01L27/28 ,  G11C13/02 ,  H01L2924/0002 ,  H01L2924/00

摘要： A method for tailoring at least portions of an exposed non-planar layered surface of a conductive layer formed on a substrate having a first surface roughness to provide the exposed surface with a second surface roughness. The method includes: forming the conductive layer on the substrate; and tailoring at least portions of the exposed surface of the conductive layer in a plasma to at least smooth the exposed surface of the conductive layer, whereby the second surface roughness is essentially the same as the first surface roughness.

摘要翻译： 一种用于调整形成在具有第一表面粗糙度的基底上的导电层的暴露的非平面层状表面的至少一部分以提供具有第二表面粗糙度的暴露表面的方法。 该方法包括：在基板上形成导电层; 以及在等离子体中定制导电层的暴露表面的至少部分，以至少平滑导电层的暴露表面，由此第二表面粗糙度基本上与第一表面粗糙度相同。

公开(公告)号：US20050056867A1

公开(公告)日：2005-03-17

申请号：US10665189

申请日：2003-09-16

申请人： Krzysztof Nauka ,  Zhiyong Li ,  Theodore Kamins

发明人： Krzysztof Nauka ,  Zhiyong Li ,  Theodore Kamins

IPC分类号： G01N27/00 ,  G01N27/12 ,  H01G9/20 ,  H01L29/768

CPC分类号： H01G9/2031 ,  G01N27/002 ,  Y02E10/542 ,  Y02P70/521

摘要： Surface photovoltage is used for molecule sensing. The sensing is performed by exposing a surface of a semiconductor to molecules, and sensing a change in surface photovoltage of the semiconductor. Chemical and biological sensors may be based on such sensing.

摘要翻译： 表面光电压用于分子感测。 通过将半导体的表面暴露于分子并感测半导体的表面光电压的变化来进行感测。 化学和生物传感器可以基于这种感测。

公开(公告)号：US06855647B2

公开(公告)日：2005-02-15

申请号：US10405294

申请日：2003-04-02

申请人： Patricia A. Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

发明人： Patricia A. Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

IPC分类号： H01L21/28 ,  G11C13/02 ,  H01L21/285 ,  H01L27/28 ,  H01L29/06 ,  H01L21/26

CPC分类号： H01L27/28 ,  G11C13/02 ,  H01L2924/0002 ,  H01L2924/00

摘要： A method is provided for fabricating molecular electronic devices comprising at least a bottom electrode and a molecular switch film on the bottom electrode. The method includes forming the bottom electrode by a process including: cleaning portions of the substrate where the bottom electrode is to be deposited; pre-sputtering the portions; depositing a conductive layer on at least the portions; and cleaning the top surface of the conductive layer. Advantageously, the conductive electrode properties include: low or controlled oxide formation (or possibly passivated), high melting point, high bulk modulus, and low diffusion. Smooth deposited film surfaces are compatible with Langmuir-Blodgett molecular film deposition. Tailored surfaces are further useful for SAM deposition. The metallic nature gives high conductivity connection to molecules. Barrier layers may be added to the device stack, i.e., Al2O3 over the conductive layer.

公开(公告)号：US20050026427A1

公开(公告)日：2005-02-03

申请号：US10930062

申请日：2004-08-30

申请人： Patricia Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

发明人： Patricia Beck ,  Douglas Ohlberg ,  Duncan Stewart ,  Zhiyong Li

IPC分类号： H01L21/28 ,  G11C13/02 ,  H01L21/285 ,  H01L27/28 ,  H01L29/06 ,  H01L21/00

CPC分类号： H01L27/28 ,  G11C13/02 ,  H01L2924/0002 ,  H01L2924/00

摘要： A method is provided for fabricating molecular electronic devices comprising at least a bottom electrode and a molecular switch film on the bottom electrode. The method includes forming the bottom electrode by a process including: cleaning portions of the substrate where the bottom electrode is to be deposited; pre-sputtering the portions; depositing a conductive layer on at least the portions; and cleaning the top surface of the conductive layer. Advantageously, the conductive electrode properties include: low or controlled oxide formation (or possibly passivated), high melting point, high bulk modulus, and low diffusion. Smooth deposited film surfaces are compatible with Langmuir-Blodgett molecular film deposition. Tailored surfaces are further useful for SAM deposition. The metallic nature gives high conductivity connection to molecules. Barrier layers may be added to the device stack, i.e., Al2O3 over the conductive layer.

摘要翻译： 提供了一种用于制造分子电子器件的方法，该分子电子器件至少包括底部电极和底部电极上的分子开关膜。 该方法包括通过以下工艺形成底部电极，该方法包括：清洗要沉积底部电极的衬底的部分; 预溅射部分; 在至少部分上沉积导电层; 并清洁导电层的顶表面。 有利地，导电电极的性质包括：低或受控的氧化物形成（或可能钝化），高熔点，高体积弹性模量和低扩散。 光滑的沉积膜表面与Langmuir-Blodgett分子膜沉积相容。 定制的表面对于SAM沉积是更有用的。 金属性质使分子具有高导电性。 阻挡层可以被添加到器件堆叠，即在导电层上的Al 2 O 3。