公开(公告)号：US10857538B2

公开(公告)日：2020-12-08

申请号：US15780814

申请日：2016-12-05

Applicant: TTP Plc

Inventor： Piers Sebastian Harding ,  Gary Stephen Howard ,  Gary Keith Jepps

IPC: B01L7/00 ,  C12N15/10 ,  G01N35/10 ,  G01N35/00 ,  G01N35/04 ,  B01L3/00 ,  B01L3/02

Abstract: A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable head comprising a pipette tip, the head being configured, in use, to be moved between a position in which the pipette tip is in sealed engagement with the fixed section of pipette component and a position in which pipette tip is positioned adjacent to another of said plural segments. With the present invention a disposable sample preparation cartridge and corresponding analytical reader can be provided in a very cost effective and simple manner whilst still ensuring high quality sample preparation for analysis.

公开(公告)号：US12228586B2

公开(公告)日：2025-02-18

申请号：US18379263

申请日：2023-10-12

Applicant: TTP Plc

Inventor： Richard Janse Van Rensburg ,  Benjamin James Metcalf

IPC: G01N35/10

Abstract: There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises: a fluid flow channel for receiving, in use, the flow of fluid; a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid; a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.

公开(公告)号：US20240390610A1

公开(公告)日：2024-11-28

申请号：US18793175

申请日：2024-08-02

Applicant: TTP PLC

Inventor： David Cottenden ,  Jianye Wang ,  Duncan Young ,  Desmond Cheung ,  Simon Waddelow ,  Iain McDerment ,  Rob Selby ,  Catherine Wyman ,  Rob May ,  Chris Groombridge

IPC: A61M15/00

Abstract: A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of the opened compartment.

公开(公告)号：US20240260958A1

公开(公告)日：2024-08-08

申请号：US18570143

申请日：2022-06-15

Applicant: TTP Plc.

Inventor： Adrian Woodward

IPC: A61B17/04 ,  A61B17/06 ,  A61B17/062

CPC classification number: A61B17/0469 ,  A61B17/06061 ,  A61B17/0625

Abstract: A suturing tool for an endoscope or a laparoscope, the tool comprising: a symmetric suturing needle comprising a point at each end of the needle; and a pair of jaws for suturing a target object between the jaws, each jaw comprising a needle holder for holding the suturing needle, the pair of jaws being configured to move between an open jaw position and a closed jaw position, wherein each needle holder comprises a moveable locking element configured to move between a closed lock position in which the suturing needle is held by the needle holder and an open lock position at which the suturing needle is released by the needle holder, and each needle holder further comprises a resilient control mechanism configured to switch the locking element between the closed lock position and the open lock position.

公开(公告)号：US12017243B2

公开(公告)日：2024-06-25

申请号：US17298975

申请日：2019-12-03

Applicant: TTP plc

Inventor： Alon Greenenko ,  Robert Gordon Maurice Selby ,  David Pooley

IPC: B05B17/00 ,  B05B17/06

CPC classification number: B05B17/0646 ,  B05B17/0653

Abstract: A liquid droplet production apparatus comprising a perforate membrane and an actuator. The actuator is configured to vibrate the perforate membrane such that a liquid in contact with the perforate membrane during use is caused to pass through at least one aperture of the perforate membrane and to be ejected as liquid droplets from the perforate membrane. The perforate membrane includes one or more stiffening structures for increasing the stiffness of the perforate membrane, the one or more stiffening structures each being defined by a local transverse deformation of the perforate membrane. A removable cartridge, a perforate membrane, an actuator assembly for use in such a liquid droplet delivery apparatus, and a method of manufacturing a perforate membrane for such a liquid droplet apparatus.

公开(公告)号：US11986848B2

公开(公告)日：2024-05-21

申请号：US16966168

申请日：2019-01-31

Applicant: TTP Plc

Inventor： Wayne Bowen ,  David Pooley

IPC: B05B17/06 ,  B01J19/00 ,  B01L3/02 ,  B41J2/14 ,  H10N30/20

CPC classification number: B05B17/0615 ,  B01J19/0046 ,  B01L3/0241 ,  B41J2/14008 ,  H10N30/20 ,  B01L2400/0436

Abstract: An acoustic droplet ejection apparatus comprises an acoustic actuator and a fluid well having abase and at least one side wall. The actuator is arranged to couple acoustic energy into the fluid well through the side wall.

公开(公告)号：US20240077587A1

公开(公告)日：2024-03-07

申请号：US18039885

申请日：2021-12-03

Applicant: TTP Plc.

Inventor： Tom JELLICOE ,  Alex CONEY ,  Neil GRIFFIN

IPC: G01S7/481

CPC classification number: G01S7/4816

Abstract: A receiver for a lidar system. The receiver comprises a monolithic block of optically transmissive material, the block shaped to define a planar light receiving surface, a first reflective surface and a second reflective surface positioned adjacent to the light receiving surface. The surfaces are positioned such that light from a distant on-axis source passing through the light receiving surface passes through the block to the first reflective surface and is reflected thereby towards the second reflective surface and in turn reflected thereby to pass through a receiving aperture formed in the first reflective surface and to come to a focus at or after the receiving aperture.

公开(公告)号：US20230212651A1

公开(公告)日：2023-07-06

申请号：US17629864

申请日：2020-07-24

Applicant: TTP PLC

Inventor： Rebecca Louise Howard ,  Kathrin Herbst ,  Giles Hugo William Sanders

IPC: C12Q1/6816 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6816 ,  C12Q1/6806 ,  C12Q1/686

Abstract: There is provided a method of detecting the presence of a nucleic acid target sequence in which two oligonucleotides are used to forma three-way junction with the target sequence to allow detection of the target sequence. Alternatively, three oligonucleotides can be used to form a four-way junction with the target sequence to allow detection of the target sequence.

公开(公告)号：US20220239506A1

公开(公告)日：2022-07-28

申请号：US17620421

申请日：2020-06-18

Applicant: TTP Plc.

Inventor： Timothy John PALMER ,  Michael BECK

IPC: H04L9/32 ,  H03K19/17768 ,  H03K19/003

Abstract: A physically unclonable function (PUF) comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least of portion of each of the conductors and further defines at least one cavity, where the cavity is structured to provide the device with an environmentally dependent characteristic. Circuitry applies an electrical challenge signal to at least one of the conductors and receives an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.

公开(公告)号：US20220119749A1

公开(公告)日：2022-04-21

申请号：US17568054

申请日：2022-01-04

Applicant: TTP Plc

Inventor： Edwin STONE ,  Peter CROSSLEY

IPC: C12M1/00 ,  C12M1/26 ,  C12M1/34

Abstract: A consumable container for filling with a fluid in a bioprocessing process. The container comprises one or more sealable, removable portions, such that one or more samples of the fluid may be taken by sealing and removing one or more of said portions.