公开(公告)号：US20190298757A1

公开(公告)日：2019-10-03

申请号：US16302578

申请日：2017-05-05

申请人： UNIVERSITY OF COPENHAGEN ,  SJÆLLANDS UNIVERSITETSHOSPITAL

发明人： Daniel BAR-SHALOM ,  Peter VILMANN ,  Anette MÜLLERTZ ,  Jacob Kolstrup ZEDERKOF ,  Hanne HOLM ,  Jette JACOBSEN

IPC分类号： A61K31/765 ,  A61K47/36 ,  A61K9/10 ,  A61K31/7016 ,  A61K31/723 ,  A61K31/732 ,  A61K31/737 ,  A61K36/04 ,  A61K45/06 ,  A61P1/10 ,  A61K9/00 ,  A61K47/46

摘要： The present invention relates to a GI-cleansing composition comprising i) one or more gelling or swelling agents, ii) one or more laxative agents, iii) one of more taste-improving agents, and iv) water.

公开(公告)号：US20180332873A1

公开(公告)日：2018-11-22

申请号：US16043899

申请日：2018-07-24

申请人： Kent Precision Foods Group, Inc.

发明人： Douglas A. Stetzer

IPC分类号： A23L2/52 ,  A61K31/723 ,  A23L33/00 ,  A23L29/20 ,  A23L29/269 ,  C12G3/04 ,  C12G1/00 ,  C12C5/02 ,  A23B7/157 ,  A61K47/02

CPC分类号： A23L2/52 ,  A23B7/157 ,  A23L29/20 ,  A23L29/27 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/723 ,  A61K47/02 ,  C12C5/02 ,  C12G1/00 ,  C12G3/04 ,  C12G2200/21 ,  A23V2200/242 ,  A23V2250/5086 ,  A23V2200/10 ,  A23V2250/51086 ,  A23V2200/32

摘要： The invention provides a food and water thickener and a method for preparing the food and water thickener. The food thickener comprises pretreated mineral water, xanthan, food preservative, a first antimicrobial and chelating agent, and a sequestering agent, wherein the food thickener has a density of between 750 and 1250 grams per liter. The method for producing the thickener incorporates pretreatment of mineral water and xanthan, and specific heating steps. Also provided is method for producing thickened alcoholic beverages. The invention further provides a method for invoking a swallow response in dysphagic patients, the method comprising increasing the mass of food to between 750 mg per liter and 1500 mg per liter; and orally administering the food to dysphagic patients.

公开(公告)号：US09801926B2

公开(公告)日：2017-10-31

申请号：US14296759

申请日：2014-06-05

申请人： Sweet Relief, Inc.

发明人： Mark A. Lannes ,  Lisa C. Lannes ,  Joe D. Stubblefield

IPC分类号： A61K38/46 ,  A61K38/48 ,  A61K31/10 ,  A61K36/886 ,  A61K36/889 ,  A61K36/752 ,  A61K36/736 ,  A61K36/534 ,  A61K36/87 ,  A61K36/22 ,  A61K36/30 ,  A61K36/61 ,  A61K36/28 ,  A61K31/723

CPC分类号： A61K38/4873 ,  A61K31/10 ,  A61K31/723 ,  A61K36/22 ,  A61K36/28 ,  A61K36/30 ,  A61K36/534 ,  A61K36/61 ,  A61K36/736 ,  A61K36/752 ,  A61K36/87 ,  A61K36/886 ,  A61K36/889 ,  A61K2300/00

摘要： A method, product by process, and composition for aiding in pain relief. The user adds hot water to methylsulfonylmethane (MSM), then stirs the resulting mixture until the MSM is dissolved. The user then adds room temperature water, bromelain, aloe vera juice, and papain to the batch, and continues to stir. Coconut oil and palm kernel oil are stirred in, along with a sweet oil mixture. The sweet oil mixture is a mixture of natural, unconcentrated, oils such as lemon oil, sweet orange oil, arnica, sweet almond oil, peppermint oil, grape seed oil, comfrey oil, eucalyptus oil, grapefruit seed extract, and fragrance oils such as mango and kiwi. Finally, xanthan gum is stirred into the mixture, resulting in a batch of desired composition, which can be used topically for pain relief.

公开(公告)号：US20170232048A1

公开(公告)日：2017-08-17

申请号：US15436606

申请日：2017-02-17

申请人： RENUZORAL LLC

发明人： STEVEN J. EDWARDS

IPC分类号： A61K35/747 ,  A61K9/00 ,  A61K35/744 ,  A61K8/99 ,  A61K8/73 ,  A61K31/733 ,  A61K8/97 ,  A61K36/48 ,  A61K31/715 ,  A61K31/723 ,  A61K47/26 ,  A61K8/60 ,  A61K47/38 ,  A61K47/36 ,  A61K47/10 ,  A61K8/34 ,  A61K47/02 ,  A61K8/24 ,  A61K47/46 ,  A61K47/12 ,  A61K8/36 ,  A61Q11/00 ,  A61K8/02

CPC分类号： A61K35/747 ,  A61K8/0208 ,  A61K8/73 ,  A61K8/731 ,  A61K8/733 ,  A61K8/97 ,  A61K8/99 ,  A61K9/0056 ,  A61K31/715 ,  A61K31/723 ,  A61K31/733 ,  A61K35/744 ,  A61K36/48 ,  A61K2035/11 ,  A61K2800/92 ,  A61Q11/00 ,  A61K2300/00

摘要： Provided is a more effective dental synbiotic lozenge that is intra-orally adhesive. The lozenge contains adhesive prebiotics and excipients, and one or more species of probiotic organisms. While safely adhered to an intra-oral surface, the lozenge dissolves to provide a controlled time-release of the excipients, prebiotics, and probiotic organisms over a period of hours instead of minutes. The lozenge dissolves into a malleable biofilm that includes a natural biofilm formed by the prebiotics and a supplemental biofilm formed by the excipients. The lozenge can be used while sleeping, which can increase probiotic availability exponentially. The result is a lozenge that allows for a smaller, but more diverse, microbial payload that can grow over time such that a fewer number of organisms are needed from the start. In one embodiment, the lozenge contains adhesive prebiotics acacia and inulin, along with additional excipients microcrystalline cellulose, HPMC K15, and sodium alginate.

公开(公告)号：US09585836B2

公开(公告)日：2017-03-07

申请号：US13021996

申请日：2011-02-07

申请人： Peter Quagliano

发明人： Peter Quagliano

IPC分类号： A61K49/04 ,  A61K49/10 ,  A61K31/723 ,  A61K31/047 ,  A61K8/63 ,  A61K9/00

CPC分类号： A61K9/0095

摘要： The invention relates to liquid vehicles that can be used to create dilute solutions of water-soluble pharmaceutical or non-pharmaceutical oral contrast agents. The liquid vehicles are formulated to provide desired osmolalities, viscosities, pH, and taste masking capabilities to match the particular intentions of the user and to complement the inherent differences in the various oral contrast agents. The liquid vehicles comprise an aqueous medium, an osmotic agent to adjust osmolality, a buffering agent, a viscosity agent, and sweeteners and flavoring agents to improve palatability.

摘要翻译： 本发明涉及可用于产生水溶性药物或非药物口服造影剂的稀溶液的液体载体。 液体载体配制成提供所需的渗透压，粘度，pH和味道掩蔽能力以匹配使用者的特定意图并补充各种口服造影剂的固有差异。 液体载体包括水性介质，调节渗透压的渗透剂，缓冲剂，粘度剂，甜味剂和调味剂以改善适口性。

公开(公告)号：US09072767B2

公开(公告)日：2015-07-07

申请号：US13993712

申请日：2011-12-16

申请人： Jonathan Albert Margossian ,  Nicolas Pradeau ,  Yannick Fallourd

发明人： Jonathan Albert Margossian ,  Nicolas Pradeau ,  Yannick Fallourd

IPC分类号： A61K36/00 ,  A61K31/717 ,  A23L1/0524 ,  A23L1/0526 ,  A23L1/0534 ,  A23L1/054 ,  A23L1/29 ,  A23L1/308 ,  A61K31/723 ,  A61K31/732

CPC分类号： A61K31/732 ,  A23L29/231 ,  A23L29/238 ,  A23L29/262 ,  A23L29/27 ,  A23L33/21 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/717 ,  A61K31/723 ,  A23V2200/244 ,  A23V2250/50724 ,  A23V2250/5086

摘要： The invention relates to compositions intended for reducing, ideally for eliminating, regurgitation and/or gastro-oesophageal reflux phenomena affecting a subject. Anti-regurgitation and/or anti-reflux infant formulas and milks intended for feeding newborn babies, infants and young children are more particularly described.

摘要翻译： 本发明涉及旨在减少，理想地用于消除影响受试者的反流和/或胃食管反流现象的组合物。 更具体地描述了用于喂养新生婴儿，婴儿和幼儿的抗反流和/或抗反流婴儿配方奶和奶。

公开(公告)号：US09050357B2

公开(公告)日：2015-06-09

申请号：US12719549

申请日：2010-03-08

申请人： Zhi-Fa Yang ,  Todd Talashek ,  Wei Li

发明人： Zhi-Fa Yang ,  Todd Talashek ,  Wei Li

IPC分类号： A61K31/723 ,  A61K9/00 ,  A61K47/36

CPC分类号： A61K31/723 ,  A61K9/0095 ,  A61K47/36

摘要： Compositions are provided that are suitable for safe consumption by a patient with dysphagia. In one embodiment, the compositions include a modified xanthan gum in an amount suitable to provide a viscous, free-flowing solution having gel-like properties. The modified xanthan gum comprises a non-pyruvylated xanthan gum, a reduced-pyruvylated xanthan gum, or a combination thereof. The composition desirably has a viscosity of greater than about 2000 cP and is characterized as having a shape retention of greater than about 50%. Also provided are methods for their preparation and use.

摘要翻译： 提供适合于患有吞咽困难的患者安全消费的组合物。 在一个实施方案中，组合物包括适量提供具有凝胶状特性的粘性，自由流动的溶液的量的改性黄原胶。 改性黄原胶包含非丙酮酸化的黄原胶，还原丙酮酸化的黄原胶，或其组合。 组合物理想地具有大于约2000cP的粘度，并且其特征在于具有大于约50％的形状保持率。 还提供了它们的制备和使用的方法。

公开(公告)号：US08450295B2

公开(公告)日：2013-05-28

申请号：US12767185

申请日：2010-04-26

申请人： Koji Doi ,  Hiroshi Aki

发明人： Koji Doi ,  Hiroshi Aki

IPC分类号： A61K31/723 ,  A61K31/198 ,  A61K31/145

CPC分类号： A61K31/723 ,  A61K31/195 ,  A61K31/198 ,  A61K31/737 ,  A61K2300/00

摘要： The present invention provides an ophthalmic composition containing xanthan gum, or xanthan gum and an amino acid, which has a superior corneal epithelial disorder-treating effect and a superior corneal epithelial cell-protecting effect.

摘要翻译： 本发明提供了含有黄原胶或黄原胶和氨基酸的眼用组合物，其具有优异的角膜上皮病症治疗作用和优异的角膜上皮细胞保护作用。

公开(公告)号：US20120269845A2

公开(公告)日：2012-10-25

申请号：US12767185

申请日：2010-04-26

申请人： Koji DOI ,  Hiroshi AKI

发明人： Koji DOI ,  Hiroshi AKI

IPC分类号： A61K31/723 ,  A61P27/02

CPC分类号： A61K31/723 ,  A61K31/195 ,  A61K31/198 ,  A61K31/737 ,  A61K2300/00

摘要： The present invention provides an ophthalmic composition containing xanthan gum, or xanthan gum and an amino acid, which has a superior corneal epithelial disorder-treating effect and a superior corneal epithelial cell-protecting effect.

摘要翻译： 本发明提供了含有黄原胶或黄原胶和氨基酸的眼用组合物，其具有优异的角膜上皮病症治疗作用和优异的角膜上皮细胞保护作用。

公开(公告)号：US07422763B2

公开(公告)日：2008-09-09

申请号：US10157296

申请日：2002-05-29

申请人： Bryan W. Wolf ,  Bruce B. Blidner ,  Keith A. Garleb ,  Chron-Si Lai

发明人： Bryan W. Wolf ,  Bruce B. Blidner ,  Keith A. Garleb ,  Chron-Si Lai

IPC分类号： A61K31/723 ,  A61K31/731 ,  A61K31/732 ,  A61K31/734 ,  A61K31/736 ,  A23L1/0524

CPC分类号： A61K45/06 ,  A23L19/115 ,  A23L29/231 ,  A23L29/238 ,  A23L29/244 ,  A23L29/256 ,  A23L29/262 ,  A23L29/27 ,  A23L29/271 ,  A23L29/272 ,  A23L29/35 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/175 ,  A23L33/19 ,  A23L33/21 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/715 ,  A61K31/718 ,  A61K33/00 ,  A61K36/185 ,  A61K36/286 ,  A61K36/31 ,  A61K36/47 ,  A61K36/48 ,  A61K36/483 ,  A61K36/81 ,  A61K36/888 ,  A61K36/899 ,  Y10S514/866 ,  Y10S514/909 ,  Y10S514/911 ,  A61K2300/00 ,  A23V2250/5114 ,  A23V2250/5026 ,  A23V2250/506 ,  A23V2250/61 ,  A23V2250/5028 ,  A23V2250/51084 ,  A23V2250/16 ,  A23V2250/1578 ,  A23V2250/54252 ,  A23V2250/702 ,  A23V2250/54246 ,  A23V2250/0644 ,  A23V2250/0612 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2250/1882 ,  A23V2250/211 ,  A23V2250/5424 ,  A23V2250/606 ,  A23V2200/3202 ,  A23V2250/304 ,  A23V2250/264 ,  A23V2250/5118 ,  A23V2200/328 ,  A23V2200/332

摘要： The present invention relates generally to a method of blunting the postprandial glycemic response to a meal by feeding an acid controlled induced viscosity fiber system. The first component of the induced viscosity fiber system is anionic soluble fiber. The second component of the induced viscosity fiber system is water-insoluble, acid-soluble multivalent cations. The fiber system will typically be incorporated into a meal replacement nutritional.The present invention also refers to a method of delivering soluble fiber to diabetics and to persons needing to lose weight. Additionally, the invention refers to a method of promoting the feeling of fullness and satiety by feeding a nutritional product containing the induced viscosity fiber system.

摘要翻译： 本发明一般涉及通过喂食酸控制的诱导粘度纤维系统使餐后血糖反应平缓的方法。 诱导粘度纤维体系的第一个成分是阴离子可溶性纤维。 诱导粘度纤维体系的第二部分是水不溶性，酸溶性多价阳离子。 纤维系统通常将被并入膳食替代营养。 本发明还涉及将可溶性纤维递送到糖尿病患者和需要减肥的人的方法。 此外，本发明涉及通过喂养含有诱导粘度纤维系统的营养产品来促进丰满感和饱腹感的方法。