公开(公告)号：US20100125139A1

公开(公告)日：2010-05-20

申请号：US12619884

申请日：2009-11-17

申请人： Donald BANKSTON ,  Dhanaphalan Nagarathnam ,  Davoud Asgari ,  Jianxing Shao ,  Xiao-Gao Liu ,  Uday Khire ,  Chunguang Wang ,  Barry Hart ,  Stephen Boyer ,  Olaf Weber ,  Mark Lynch

发明人： Donald BANKSTON ,  Dhanaphalan Nagarathnam ,  Davoud Asgari ,  Jianxing Shao ,  Xiao-Gao Liu ,  Uday Khire ,  Chunguang Wang ,  Barry Hart ,  Stephen Boyer ,  Olaf Weber ,  Mark Lynch

IPC分类号： C07D403/12 ,  C07D239/91 ,  C07D405/14 ,  C07D239/93

CPC分类号： C07D307/79 ,  C07D239/86 ,  C07D239/91 ,  C07D239/93 ,  C07D403/12 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14

摘要： A process for the preparation of various quinazoline compounds which are useful as Rho-Kinase inhibitors, and thus having utility in the treatment of hypertension and other indications.

摘要翻译： 用于制备可用作Rho-激酶抑制剂的各种喹唑啉化合物的方法，因此可用于治疗高血压和其他适应症。

公开(公告)号：US07648986B2

公开(公告)日：2010-01-19

申请号：US11733045

申请日：2007-04-09

申请人： Dhanapalan Nagarathnam ,  Uday Khire ,  Davoud Asgari ,  Jianxing Shao ,  Xiao-Gao Liu ,  Chunguang Wang ,  Barry Hart ,  Olaf Weber ,  Mark Lynch ,  Lei Zhang ,  Lei Wang

发明人： Dhanapalan Nagarathnam ,  Uday Khire ,  Davoud Asgari ,  Jianxing Shao ,  Xiao-Gao Liu ,  Chunguang Wang ,  Barry Hart ,  Olaf Weber ,  Mark Lynch ,  Lei Zhang ,  Lei Wang

IPC分类号： C07D495/04 ,  C07D251/16 ,  C07D413/10 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/53 ,  A61K31/497 ,  A61K31/496 ,  A61K31/498 ,  A61P9/12 ,  A61P9/10 ,  A61P35/04 ,  A61P11/06 ,  C07D401/12 ,  C07D401/14

CPC分类号： C07D471/04 ,  C07D491/04 ,  C07D495/04

摘要： Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.

摘要翻译： 公开了其化合物及其衍生物的合成及其作为Rho-激酶抑制剂的用途。 本发明的这些化合物可用于抑制肿瘤生长，治疗勃起功能障碍，以及治疗由Rho-激酶（例如冠心病）介导的其它适应症。

公开(公告)号：US20060118768A1

公开(公告)日：2006-06-08

申请号：US11293681

申请日：2005-12-02

申请人： Gao Liu ,  Stephen Johnson ,  John Kerr ,  Andrew Minor ,  Samuel Mao

发明人： Gao Liu ,  Stephen Johnson ,  John Kerr ,  Andrew Minor ,  Samuel Mao

IPC分类号： H01B1/00 ,  H01L51/46 ,  H01L51/54

CPC分类号： H01L51/0049 ,  B82Y10/00 ,  H01L51/0067 ,  H01L51/5012 ,  Y02E10/549 ,  Y10S428/917

摘要： A thin film device and compound having an anode, a cathode, and at least one light emitting layer between the anode and cathode, the at least one light emitting layer having at least one carbon nanotube and a conductive polymer.

摘要翻译： 一种在阳极和阴极之间具有阳极，阴极和至少一个发光层的薄膜器件和化合物，所述至少一个发光层具有至少一个碳纳米管和导电聚合物。

公开(公告)号：US20060024296A1

公开(公告)日：2006-02-02

申请号：US10982357

申请日：2004-11-05

申请人： Marna Williams ,  J. Tso ,  Nicholas Landolfi ,  David Powers ,  Robert DuBridge ,  Debbie Law ,  Gao Liu

发明人： Marna Williams ,  J. Tso ,  Nicholas Landolfi ,  David Powers ,  Robert DuBridge ,  Debbie Law ,  Gao Liu

IPC分类号： A61K39/395 ,  C07K16/44

CPC分类号： C07K16/2803 ,  A61K2039/505 ,  C07K14/70503 ,  C07K16/2806 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/00 ,  C07K2319/30

摘要： The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.

公开(公告)号：US10833320B2

公开(公告)日：2020-11-10

申请号：US16043051

申请日：2018-07-23

申请人： Gao Liu ,  Guo Ai ,  Hui Zhao

发明人： Gao Liu ,  Guo Ai ,  Hui Zhao

IPC分类号： H01M4/36 ,  H01M10/052 ,  H01M4/58 ,  H01M4/66 ,  H01M4/62 ,  H01M4/136 ,  H01M4/60 ,  H01M2/16 ,  H01M4/02

摘要： The present invention provides for a composition of matter comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for an electrode comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for a lithium sulfur (Li—S) battery comprising: an electrode comprising poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous.

公开(公告)号：US10340508B2

公开(公告)日：2019-07-02

申请号：US14741383

申请日：2015-06-16

申请人： Gao Liu ,  Hui Zhao

发明人： Gao Liu ,  Hui Zhao

IPC分类号： H01M4/36 ,  H01B1/12 ,  H01M4/38 ,  H01M4/66 ,  H01M4/04 ,  H01M4/62 ,  H01M10/0525 ,  H01B1/22 ,  H01M4/13 ,  H01M4/48 ,  H01M4/02

摘要： The invention demonstrates that only 2% functional conductive polymer binder without any conductive additives was successfully used with a micron-size silicon monoxide (SiO) anode material, demonstrating stable and high gravimetric capacity (>1000 mAh/g) for ˜500 cycles and more than 90% capacity retention. Prelithiation of this anode using stabilized lithium metal powder (SLMP®) improves the first cycle Coulombic efficiency of a SiO/NMC full cell from ˜48% to ˜90%. This combination enables good capacity retention of more than 80% after 100 cycles at C/3 in a lithium-ion full cell. We also demonstrate the important connection between porosity and the loading of silicon electrodes. By employing a highly porous silicon electrode, a high areal capacity (3.3 mAh/cm2) is obtained. This method works well to achieve high loading of other high-capacity alloy anodes, the state-of-art graphite anode, as well as a high loading of positive electrodes for LIBs.

公开(公告)号：US10170765B2

公开(公告)日：2019-01-01

申请号：US14863486

申请日：2015-09-24

申请人： Gao Liu ,  Vincent S. Battaglia ,  Sang-Jae Park

发明人： Gao Liu ,  Vincent S. Battaglia ,  Sang-Jae Park

IPC分类号： H01B1/22 ,  C08F212/00 ,  H01M4/00 ,  H01M4/62 ,  H01B1/12 ,  H01B1/24 ,  C08F212/32 ,  B82Y30/00 ,  C08J5/00 ,  C08G61/02 ,  C08K3/08 ,  H01M4/134 ,  H01M4/1395 ,  H01M4/38 ,  C09D5/24 ,  C09D133/10 ,  C09D133/14 ,  H01M4/04 ,  H01M10/0525 ,  H01M4/36 ,  H01M4/587

摘要： A family of carboxylic acid groups containing fluorene/fluorenon copolymers is disclosed as binders of silicon particles in the fabrication of negative electrodes for use with lithium ion batteries. Triethyleneoxide side chains provide improved adhesion to materials such as, graphite, silicon, silicon alloy, tin, tin alloy. These binders enable the use of silicon as an electrode material as they significantly improve the cycle-ability of silicon by preventing electrode degradation over time. In particular, these polymers, which become conductive on first charge, bind to the silicon particles of the electrode, are flexible so as to better accommodate the expansion and contraction of the electrode during charge/discharge, and being conductive promote the flow battery current.

公开(公告)号：US10079387B2

公开(公告)日：2018-09-18

申请号：US14632907

申请日：2015-02-26

申请人： Gao Liu ,  Hui Zhao

发明人： Gao Liu ,  Hui Zhao

IPC分类号： C07C235/74 ,  H01M4/62 ,  H01M4/04 ,  H01M4/134 ,  H01M4/1395 ,  H01M4/38 ,  H01M4/66 ,  C07C235/78 ,  H01M4/02 ,  H01M10/0525

CPC分类号： H01M4/622 ,  C07C235/74 ,  C07C235/78 ,  H01M4/0404 ,  H01M4/134 ,  H01M4/1395 ,  H01M4/386 ,  H01M4/387 ,  H01M4/661 ,  H01M10/0525 ,  H01M2004/027 ,  Y02E60/122

摘要： A Poly(1-pyrenemethyl methacrylate-co-dopamine methacrylamide) PPyDMA polymer binder has been designed and fabricated, and has demonstrated an excellent performance for silicon (Si), graphite and a metal alloy anode materials. The PPyDMA polymer binder demonstrates the great potential of a catechol moiety for use in a lithium-ion battery.

公开(公告)号：US20180034041A1

公开(公告)日：2018-02-01

申请号：US15644364

申请日：2017-07-07

申请人： Gao Liu

发明人： Gao Liu

IPC分类号： H01M4/134 ,  H01M4/66 ,  H01M4/04 ,  H01M4/1395 ,  H01M4/38 ,  H01M4/60 ,  H01M10/0525 ,  H01B1/12 ,  H01M4/62 ,  H01M4/36

CPC分类号： H01M4/134 ,  H01B1/12 ,  H01M4/0416 ,  H01M4/1395 ,  H01M4/366 ,  H01M4/386 ,  H01M4/602 ,  H01M4/623 ,  H01M4/661 ,  H01M10/0525 ,  H01M2220/20 ,  Y02T10/7011

摘要： Embodiments of the present invention disclose a composition of matter comprising a silicon (Si) nanoparticle coated with a conductive polymer. Another embodiment discloses a method for preparing a composition of matter comprising a plurality of silicon (Si) nanoparticles coated with a conductive polymer comprising providing Si nanoparticles, providing a conductive polymer, preparing a Si nanoparticle, conductive polymer, and solvent slurry, spraying the slurry into a liquid medium that is a non-solvent of the conductive polymer, and precipitating the silicon (Si) nanoparticles coated with the conductive polymer. Another embodiment discloses an anode comprising a current collector, and a composition of matter comprising a silicon (Si) nanoparticle coated with a conductive polymer.

公开(公告)号：US20170294683A1

公开(公告)日：2017-10-12

申请号：US15632153

申请日：2017-06-23

申请人： Gao Liu ,  Hui Zhao ,  Sang-Jae Park

发明人： Gao Liu ,  Hui Zhao ,  Sang-Jae Park

IPC分类号： H01M10/0569 ,  H01M4/38 ,  H01M4/58 ,  H01M10/0525 ,  H01M10/0568

CPC分类号： H01M10/0569 ,  H01M4/382 ,  H01M4/386 ,  H01M4/5825 ,  H01M4/587 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0568 ,  H01M2220/20 ,  H01M2300/0037 ,  Y02E60/122 ,  Y02T10/7011

摘要： A homologous series of cyclic carbonate or propylene carbonate (PC) analogue solvents with increasing length of linear alkyl substitutes were synthesized and used as co-solvents with PC for graphite based lithium ion half cells. A graphite anode reaches a capacity around 310 mAh/g in PC and its analogue co-solvents with 99.95% Coulombic efficiency. Cyclic carbonate co-solvents with longer alkyl chains are able to prevent exfoliation of graphite when used as co-solvents with PC. The cyclic carbonate co-solvents of PC compete for solvation of Li ion with PC solvent, delaying PC co-intercalation. Reduction products of PC on graphite surfaces via single-electron path form a stable Solid Electrolyte Interphase (SEI), which allows the reversible cycling of graphite.