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公开(公告)号：US20150133635A1
公开(公告)日：2015-05-14
申请号：US14480004
申请日：2014-09-08
Applicant: IDEMITSU KOSAN CO., LTD. , NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Kazutoshi SAWADA , Kazuya Yoshida , Takeshi Matsui
IPC: C07K14/245 , C07K14/28
CPC classification number: C07K14/245 , A61K39/00 , A61K39/0258 , A61K2039/517 , C07K14/25 , C07K14/28 , C07K2319/00 , C07K2319/55 , C12N15/8258 , Y02A50/474
Abstract: A bacterial toxin protein such as a Shiga toxin protein is efficiently produced using plant cells. The plant cells are transformed using a DNA construct containing DNA encoding a hybrid protein in which the bacterial toxin proteins such as the Shiga toxin proteins are tandemly linked through a peptide having the following characteristics (A) and (B) to produce the bacterial toxin protein in the plant cells: (A) a number of amino acids is 12 to 30; and (B) a content of proline is 20 to 35%.
Abstract translation: 使用植物细胞有效地产生细菌毒素蛋白如志贺毒素蛋白质。 使用含有编码杂合蛋白的DNA的DNA构建体转化植物细胞，其中细菌毒素蛋白如志贺毒素蛋白通过具有以下特征（A）和（B）的肽串联连接以产生细菌毒素蛋白 在植物细胞中：（A）一些氨基酸为12〜30; （B）脯氨酸含量为20〜35％。
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公开(公告)号：US12180491B2
公开(公告)日：2024-12-31
申请号：US16980266
申请日：2019-03-14
Applicant: MEDICAGO INC. , NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY , MITSUBISHI TANABE PHARMA CORPORATION
Inventor： Pierre-Oliver Lavoie , Marc-Andre D'Aoust , Ko Kato , Shotaro Yamasaki
Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbMT78 (SEQ ID NO:1); nbATL75 (SEQ ID NO:2); nbDJ46 (SEQ ID NO:3); nbCHP79 (SEQ ID NO:4); nbEN42 (SEQ ID NO:5); atHSP69 (SEQ ID NO:6); atGRP62 (SEQ ID NO:7); atPK65 (SEQ ID NO:8); atRP46 (SEQ ID NO:9); nb30S72 (SEQ ID NO:10); nbGT61 (SEQ ID NO:11); nbPV55 (SEQ ID NO:12); nbPPI43 (SEQ ID NO:13); nbPM64 (SEQ ID NO:14); and nbH2A86 (SEQ ID NO:15). Methods for using the isolated expression enhancer are also provided.
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公开(公告)号：US12168707B2
公开(公告)日：2024-12-17
申请号：US17269608
申请日：2019-08-27
Applicant: NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY , DAIKIN INDUSTRIES, LTD.
Inventor： Tsuyoshi Ando , Kayo Terada , Nobuo Murase , Shota Shibutani , Yoshito Tanaka , Takuma Kawabe , Ikuo Yamamoto
IPC: C08F265/02 , C08F255/02 , C08F265/06 , C09K3/18 , D01F11/08
Abstract: A water- and oil-repellent agent for fibers containing a bottle brush polymer having a structure represented by the following formula (1), wherein R1 is H or CH3; R2 is a divalent organic group; R3 is a polymer chain having a structure represented by the following formula (2) (wherein R4 is H or CH3; R5 is a C16-C40 monovalent hydrocarbon group; and n is an integer of 10 to 1000); and m is an integer of 10 to 5000:
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公开(公告)号：US11276194B2
公开(公告)日：2022-03-15
申请号：US17042481
申请日：2019-03-28
Inventor： Keita Tomochika , Takuya Kiyokawa , Tsukasa Ogasawara , Jun Takamatsu , Ming Ding
IPC: G06T7/70
Abstract: Provided are a method and a device that can efficiently generate a training dataset. Object information is associated with a visual marker, a training dataset generation jig that is configured from a base part and a marker is used, said base part being provided with an area that serves as a guide for positioning a target object and said marker being fixed on the base part, the target object is positioned using the area as a guide and in this condition an image group of the entire object including the marker is acquired, the object information that was associated with the visual marker is acquired from the acquired image group, a reconfigured image group is generated from this image group by performing a concealment process on a region corresponding to the visual marker or the training dataset generation jig, a bounding box is set in the reconfigured image group on the basis of the acquired object information, information relating to the bounding box, the object information, and estimated target object position information and posture information are associated with a captured image, and a training dataset for performing object recognition and position/posture estimation for the target object is generated.
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公开(公告)号：US11123324B2
公开(公告)日：2021-09-21
申请号：US16326127
申请日：2017-08-17
Inventor： Reiko Shinkura , Kota Yamamoto
IPC: A61K31/365 , A61K31/407 , A61P37/08 , A61K45/00 , A61P11/06 , A61P27/02 , A61P43/00 , A61P17/00 , A61P37/02 , A61P17/04 , A61P11/02 , A61K39/39 , A61P1/04
Abstract: The present invention provides a pharmaceutical composition to be used for the treatment or prophylaxis of allergic diseases. More specifically, the present invention provides a pharmaceutical composition to be used for the treatment or prophylaxis of allergic diseases, which contains a substance that induces selective IgA class switching in B cells. As a substance that induces selective IgA class switching in B cells, a PKC activator can be used. In addition, a composition containing a substance that induces selective IgA class switching in B cells can also be useful as a mucosal adjuvant.
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Patent Agency Ranking
公开(公告)号：US11119451B2
公开(公告)日：2021-09-14
申请号：US16537526
申请日：2019-08-10
Applicant: Yokogawa Electric Corporation , NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Takamitsu Matsubara , Yunduan Cui , Lingwei Zhu , Hiroaki Kanokogi , Morihiro Fujisaki , Go Takami , Yota Furukawa
Abstract: Provided is an apparatus including a plurality of agents that each set some devices among a plurality of devices provided in a facility to be target devices, wherein each of the plurality of agents includes a state acquiring section that acquires state data indicating a state of the facility; a control condition acquiring section that acquires control condition data indicating a control condition of each target device; and a learning processing section that uses learning data including the state data and the control condition data to perform learning processing of a model that outputs recommended control condition data indicating a control condition recommended for each target device in response to input of the state data.
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公开(公告)号：US20210246462A1
公开(公告)日：2021-08-12
申请号：US16980266
申请日：2019-03-14
Applicant: MEDICAGO INC. , NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY , MITSUBISHI TANABE PHARMA CORPORATION
Inventor： Pierre-Oliver LAVOIE , Marc-Andre D'AOUST , Ko KATO , Shotaro YAMASAKI
Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbMT78 (SEQ ID NO:1); nbATL75 (SEQ ID NO:2); nbDJ46 (SEQ ID NO:3); nbCHP79 (SEQ ID NO:4); nbEN42 (SEQ ID NO:5); atHSP69 (SEQ ID NO:6); atGRP62 (SEQ ID NO:7); atPK65 (SEQ ID NO:8); atRP46 (SEQ ID NO:9); nb30S72 (SEQ ID NO:10); nbGT61 (SEQ ID NO:11); nbPV55 (SEQ ID NO:12); nbPPI43 (SEQ ID NO:13); nbPM64 (SEQ ID NO:14); and nbH2A86 (SEQ ID NO:15). Methods for using the isolated expression enhancer are also provided.
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公开(公告)号：US20190277739A1
公开(公告)日：2019-09-12
申请号：US16319329
申请日：2017-07-21
Inventor： Takahito AOTO , Yasuhiro MUKAIGAWA
Abstract: To provide a method whereby viscoelasticity of an object can be measured nondestructively and in non-contact fashion in a short time. By this method, elastic waves and light are radiated to an object and the viscoelasticity of an object is measured nondestructively and in non-contact fashion using a shadow change based on a change in the direction of a line normal to the surface of the object. Specifically, the present invention has an elastic wave transmission step for pressurizing or exciting the object by elastic waves and causing a minute displacement of the object surface shape, a photoirradiation step for radiating light to the minutely displaced object surface, an image acquisition step for acquiring a shadow change based on a change in the direction of a line normal to the object surface, and a viscoelasticity estimation step for processing an image of the acquired shadow change and calculating a viscoelasticity.
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公开(公告)号：US20190193741A1
公开(公告)日：2019-06-27
申请号：US16227465
申请日：2018-12-20
Applicant: DENSO CORPORATION , NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Kentaro HITOMI , Kazuhito TAKENAKA , Masataka MORI , Kazushi IKEDA , Takatomi KUBO , Hiroaki SASAKI
IPC: B60W40/06 , G06K9/00 , H04W4/46 , G08G1/0967
CPC classification number: B60W40/06 , G06K9/00791 , G08G1/096791 , H04W4/46
Abstract: In an apparatus for detecting an anomaly of an evaluation target condition of a road, a storage stores a reference data set correlating to a predetermined attribute and being comprised of reference data samples. An anomaly level calculator obtains, from target vehicles, an evaluation data set correlating to the predetermined attribute and being comprised of evaluation data samples. The evaluation data samples are collected from the respective target vehicles as target driving data items at the predetermined attribute under the evaluation target condition of the road. The target driving data item for each of the target vehicles represents at least one driving operation of the corresponding one of the target vehicles. The anomaly level calculator compares the reference data set with the evaluation data set to thereby calculate an anomaly level of the evaluation target condition of the road.
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公开(公告)号：US09611461B2
公开(公告)日：2017-04-04
申请号：US14777880
申请日：2014-03-14
Inventor： Iwao Ohtsu , Takeshi Nakatani , Ai Tamakoshi , Sayo Takahashi , Hiroshi Takagi
CPC classification number: C12N9/1085 , C12N15/70 , C12P13/12 , C12Y205/01047
Abstract: L-cysteine can be produced inexpensively and efficiently by using a bacterium belonging to the family Enterobacteriaceae modified to reduce activity of O-acetylserine sulfhydrylase B thereof, the bacterium being modified so that the C terminal region of its thiosulfate-binding protein is deleted, and the bacterium having an increased ability to produce L-cysteine in the presence of a sulfate.
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