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公开(公告)号：US20240108826A1
公开(公告)日：2024-04-04
申请号：US18558126
申请日：2022-04-29
发明人： Mark Milton-Edwards
IPC分类号： A61M15/00 , A61K31/573
CPC分类号： A61M15/0065 , A61K31/573 , A61M15/0026 , A61M2205/3334 , A61M2205/3553
摘要： Provided is a pharmaceutical composition comprising an oral corticosteroid for use in post-exacerbation treatment of a respiratory disease in a subject, which post-exacerbation treatment includes an initial dose of the oral corticosteroid. The post-exacerbation treatment being continued until fulfilment of an inhalation parameter criterion by one or more post-exacerbation inhalations performed by the subject with at least one inhaler and/or fulfilment of a rescue inhaler usage criterion relating to post-exacerbation usage of a rescue inhaler configured to deliver a rescue medicament to the subject, at which point the dose of the oral corticosteroid is changed from the initial dose. Further provided are systems and methods for determining whether the inhalation parameter criterion is fulfilled and for comparing a post-exacerbation value of an inhalation parameter to a baseline value of the inhalation parameter.
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公开(公告)号：USD1018554S1
公开(公告)日：2024-03-19
申请号：US29732574
申请日：2020-04-24
设计人： Xinyu Liu
摘要： The application file contains at least one drawing executed in color. Copies of this patent application publication with a color drawing will be provided by the Office upon request and payment of the necessary fee.
The sole FIGURE is a front view of a display screen with a graphical user interface, showing our new design.
The solid line perimeter shows the display screen and forms a part of the claimed design.-
公开(公告)号：US11865247B2
公开(公告)日：2024-01-09
申请号：US17847968
申请日：2022-06-23
发明人： Daniel Buck , Paul Prendergast , Declan Walsh
CPC分类号： A61M15/0066 , A61K9/0073 , A61K31/46 , A61K31/573 , A61M15/00 , A61M15/0013 , A61M15/0021 , A61M15/0025 , A61M15/0071 , A61M15/0091 , A61M15/08 , A61P11/00 , A61P11/06 , A61M2205/18
摘要： An inhaler housing (14) for an inhaler (10) for inhaling inhalable substances, the inhaler having: a body (14) and a dose counter (24) with a return spring (28), wherein a distinct guide surface (162) is provided for guiding the end of the return spring into a recess (152), the distinct guide surface being wider than an entrance mouth (160) of the recess, a dose counter chamber (22) being provided which is separated from a tubular interior space (182) of the inhaler by a barrier (180), the barrier including a stepped upper wall area (184) including at least three steps (186, 188, 190, 192) at different levels, the inhaler having a valve stem block (62) having an inner bore and a valve stem block having a seal (224) in the inner bore with a second diameter which is smaller than a first diameter of the inner bore, the inhaler having a canister (150) being adapted to move during operation between 1 and 4 mm, a drive being arranged to apply a firing force of between 15N and 60N of force to the canister at a position of the canister relative to a valve stem (54) at which the canister fires.
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公开(公告)号：US11793953B2
公开(公告)日：2023-10-24
申请号：US17957079
申请日：2022-09-30
发明人： Daniel Buck , Paul Prendergast , Declan Walsh
IPC分类号： A61M15/00 , A61P11/06 , A61P11/00 , A61K9/00 , A61K31/439 , A61K31/569 , A61K47/06 , A61M15/08 , B65D83/38 , B65D83/54
CPC分类号： A61M15/0066 , A61K9/007 , A61K31/439 , A61K31/569 , A61K47/06 , A61M15/009 , A61M15/0025 , A61M15/0071 , A61M15/0095 , A61M15/08 , A61P11/00 , A61P11/06 , A61M15/0026 , A61M15/0078 , A61M15/0091 , A61M2205/18 , A61M2205/276 , B65D83/386 , B65D83/54
摘要： A nasal inhaler for the inhalation of inhalable substances comprise: a canister having an interior reservoir containing pressurised inhalable substances including fluid; a metering valve including a metering chamber and a valve stem defining a communication path between the metering chamber and the interior reservoir, the communication path including an opening configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas located within the metering chamber is replaced with liquid from the interior reservoir.
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公开(公告)号：US11660408B2
公开(公告)日：2023-05-30
申请号：US16571587
申请日：2019-09-16
CPC分类号： A61M15/0065 , A61M15/008 , A61M15/009 , A61M15/0026 , A61M15/0071 , A61M15/0091 , A61M15/00 , A61M16/0858 , A61M2016/0027 , A61M2202/064 , A61M2205/3331 , A61M2205/3334 , A61M2205/3358 , A61M2205/3576 , A61M2205/3584 , A61M2205/50 , A61M2205/58 , A61M2205/583 , A61M2205/584 , A61M2205/587 , A61M2209/088
摘要： An inhaler includes a mouthpiece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.
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公开(公告)号：US20220276173A1
公开(公告)日：2022-09-01
申请号：US17745686
申请日：2022-05-16
IPC分类号： G01N21/65 , A61K9/00 , A61K31/138 , A61K31/567 , A61K45/06 , G01J3/44 , G01N21/85
摘要： The present invention generally relates to improved methods for the manufacture of inhalation powders. More particularly, aspects of the disclosure relate to methods for in-line monitoring of powder blending by Raman spectroscopy.
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公开(公告)号：US20220218920A1
公开(公告)日：2022-07-14
申请号：US17594801
申请日：2020-05-01
摘要： An electronic module for a medical device such as an inhaler is disclosed, the electronic module comprising a printed circuit board, and a damper configured to dampen energy transfer to and/or from a battery when a battery is connected to the electronic module and the electronic module is exposed to mechanical shock.
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公开(公告)号：US11366064B2
公开(公告)日：2022-06-21
申请号：US17380535
申请日：2021-07-20
IPC分类号： G01N21/65 , A61K9/00 , A61K31/138 , A61K31/567 , A61K45/06 , G01J3/44 , G01N21/85
摘要： The present invention generally relates to improved methods for the manufacture of inhalation powders. More particularly, aspects of the disclosure relate to methods for in-line monitoring of powder blending by Raman spectroscopy.
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公开(公告)号：US20220168515A1
公开(公告)日：2022-06-02
申请号：US17675450
申请日：2022-02-18
摘要： An inhalation monitoring system includes an inhaler having a medicament delivery apparatus configured to deliver medicament to a user during an inhalation of the user; inhalation monitoring apparatus, configured to, during the inhalation, gather data for determining a measure of the user's lung function and/or lung health; and a processor configured to receive the data from the inhalation monitoring apparatus and, using the data, determine a measure of the user's lung function and/or lung health.
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公开(公告)号：US11344685B2
公开(公告)日：2022-05-31
申请号：US15815758
申请日：2017-11-17
发明人： Enrique Calderon Oliveras , Carl L. Lewis , Symon D'Oyly Cotton , Steven D. Gardner , Robert O. Kivlin
摘要： A device for delivering medication to a user may include a main body, an electronics module, and a slider. The main body may include a mouthpiece, a medication reservoir, and a mouthpiece cover, where the mouthpiece cover may be hinged to the main body. The electronics module may include a communication circuit, a pressure sensor, and a switch. The slider may be configured to engage the switch when the mouthpiece cover moves from a closed position to an open position. The switch may be configured to switch the electronics module from an off state or a sleep state to an active state. The electronics module may be configured to never return to the off state after the mouthpiece cover is moved to expose the mouthpiece for the first time by the user.
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