LIPOLYTIC ENZYME VARIANTS
    52.
    发明申请

    公开(公告)号:US20100003708A1

    公开(公告)日:2010-01-07

    申请号:US12443578

    申请日:2007-10-02

    IPC分类号: C12Q1/34 C12N9/14

    CPC分类号: C12N9/20 C07K2299/00

    摘要: Lipolytic enzyme variants with increased specificity for short-chain fatty acids can be designed on the basis of a three-dimensional model of a lipolytic enzyme such as C. antarctica lipase A with a substrate analogue such as a fatty acid. An amino acid residue is selected within 10 Å of the carbon atom corresponding to the desired chain-length specificity, and the selected residue is substituted with a larger residue, or an amino acid insertion is made adjacent to the selected residue.

    摘要翻译: 可以基于具有底物类似物如脂肪酸的南极洲脂肪酶A的脂肪分解酶的三维模型来设计对短链脂肪酸具有增加的特异性的脂肪分解酶变体。 在对应于所需链长度特异性的碳原子的10埃内选择氨基酸残基,并且所选择的残基被较大的残基取代,或者与选择的残基相邻地进行氨基酸插入。

    Lipase variants
    54.
    发明授权
    Lipase variants 失效
    脂肪酶变体

    公开(公告)号:US07157263B2

    公开(公告)日:2007-01-02

    申请号:US10250727

    申请日:2002-02-07

    IPC分类号: C12N9/20

    CPC分类号: C11D3/38627

    摘要: Attaching a peptide extension to the C-terminal amino acid of a lipase re-duces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.g. up to C8) such as dairy stains containing butter fat or tropical oils such as coconut oil or palm kernel oil.

    摘要翻译: 将肽延伸到脂肪酶的C末端氨基酸,导致形成气味的倾向。 这可能导致脂肪酶变体,当洗涤含有脂肪的织物污染的纺织品时,具有减少的气味产生,所述脂肪包括相对短链的脂肪酰基(例如高达C8),例如含有黄油脂肪的乳制品污渍或热带油如椰子油或棕榈仁油 。

    Lipolytic enzyme
    59.
    发明授权
    Lipolytic enzyme 失效
    脂解酶

    公开(公告)号:US5830736A

    公开(公告)日:1998-11-03

    申请号:US809426

    申请日:1997-04-04

    CPC分类号: C12N9/20 C11D3/38627

    摘要: The present invention relates to novel lipolytic enzymes. More specifically the invention provides novel lipolytic enzymes having the properties of a lipase native to the strain Fusarium culmorum CBS 513.94, or has immunochemical properties identical or partially identical to those of a lipase native to the strain Fusarium culmorum CBS 513.94.

    摘要翻译: PCT No.PCT / DK95 / 00425 Sec。 371日期1997年04月4日 102(e)日期1997年4月4日PCT提交1995年10月26日PCT公布。 第WO96 / 13579号公报 日期:1996年5月9日本发明涉及新型脂肪分解酶。 更具体地说,本发明提供了具有天然于大肠杆菌CBS 513.94菌株的脂肪酶性质的新型脂肪分解酶,或具有与大肠杆菌CBS 513.94菌株天然的脂肪酶相同或部分相同的免疫化学性质。