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公开(公告)号:US20240075046A1
公开(公告)日:2024-03-07
申请号:US18259458
申请日:2021-12-27
Inventor: David Meiri , Vered Cohen
IPC: A61K31/00 , A61K31/135 , A61P15/00 , A61P35/00
CPC classification number: A61K31/658 , A61K31/135 , A61P15/00 , A61P35/00
Abstract: The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating estrogen receptor-related diseases. The present invention further provides combination therapy comprising one or more cannabinoids and an estrogen receptor activation inhibitor and use thereof in sensitizing subjects that are resistance to treatment with the estrogen receptor activation inhibitor alone.
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公开(公告)号:US20230414639A1
公开(公告)日:2023-12-28
申请号:US18252715
申请日:2021-11-14
Inventor: David Meiri , Elazar Besser , Gil Moshe Lewitus , Paula Berman
CPC classification number: A61K31/658 , A61P17/06 , A61P35/00
Abstract: The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating NOTCH-related diseases.
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公开(公告)号:US11648260B2
公开(公告)日:2023-05-16
申请号:US17042441
申请日:2019-03-27
Inventor: Shulamit Levenberg , Shaowei Guo , Daniel Offen , Nisim Perets
IPC: C07H21/02 , C07H21/04 , A61K31/713 , A61K35/28 , A61K38/51 , C12N15/113 , A61K9/50 , C12N15/11 , A61K9/127
CPC classification number: A61K31/713 , A61K9/5068 , A61K35/28 , A61K38/51 , C12N15/111 , C12N15/113 , C12N15/1137 , A61K9/127 , C12N2310/14 , C12N2310/3515 , C12N2310/531 , C12N2320/32
Abstract: The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.
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公开(公告)号:US20230117378A1
公开(公告)日:2023-04-20
申请号:US18067702
申请日:2022-12-17
Inventor: Hossam HAICK , Muhammad KHATIB
IPC: H01L29/786 , H01L29/06 , H01L29/16 , H01L29/24 , H01L29/423 , H01L29/66
Abstract: A self-healing field-effect transistor (FET) device is disclosed in this application, the self-healing FET has a self-healing substrate, a self-healing dielectric layer, a gate electrode, at least one source electrode, at least one drain electrode, and at least one channel. The self-healing substrate and the self-healing dielectric layer have a disulfide-containing poly(urea-urethane) (PUU) polymer. The self-healing dielectric layer has a thickness of less than about 10 µm. The electrodes have electrically conductive elongated nanostructures. The at least one channel has semi-conducting elongated nanostructures.
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公开(公告)号:US11021854B2
公开(公告)日:2021-06-01
申请号:US16313173
申请日:2017-06-26
Inventor: Ben Gido , David Broday , Eran Friedler
Abstract: An atmospheric moisture harvesting system, in which water vapor is separated from the air using a liquid desiccant subsystem. The moisture charged liquid desiccant enters a desorber and condensation system, where the moisture is extracted. Cooling and condensation are performed on the extracted water vapor only, thereby saving the energy for cooling air containing the water vapor, as is done in direct cooling systems. The system thus operates as a single stage vapor separation system since the vapor concentration remains in the liquid desiccant which is circulated to the separation and condensation subsystems without air laden with the moisture. Low grade or solar heat can be used as the energy source for the vapor desorption. A heat exchanger utilizes unwanted heat from regenerated desiccant to heat up charged desiccant entering the regenerating stage. The system has substantial energy savings over prior art systems using direct cooling of air.
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公开(公告)号:US20200276045A1
公开(公告)日:2020-09-03
申请号:US16759758
申请日:2018-10-29
Inventor: MARIANA BENDAVIT
Abstract: A device for fixing in a stoma for collection of excrement, comprising a catheter, a balloon at the distal end of the device, and manual rotatable pump at the proximal end of the device. The pump has a lid that is rotatable in two directions, and the lid is attached to a paddle that moves through an annular air chamber. Rotation of the lid in one direction causes air to flow down a tube and inflate the balloon, allowing the device to be secured in place, while rotation of the lid in the opposite direction causes air to be drawn up the air tube and deflates the balloon. The device further comprises an anti-drop cup that unfolds toward the distal end of the device as the device is removed from the stoma and is adapted to collect any leakage from the stoma during removal of the device.
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公开(公告)号:US10527584B2
公开(公告)日:2020-01-07
申请号:US15818837
申请日:2017-11-21
Inventor: Moran Bercovici , Ortal Schwartz
IPC: G01N27/447 , B01L3/00
Abstract: A system comprising a protein and a channel. The channel has a domain that binds a membranal component. The channel is configured to carry a liquid sample to an isotachophoresis (ITP) apparatus. The liquid sample comprising or suspected of comprising a cell, a cell membrane or a fraction of a cell membrane. The ITP apparatus comprises a first zone and a second zone. The first zone is configured to contain a solution of high effective mobility leading electrolyte (LE) ion. The second zone is configured to contain a solution of low effective mobility trailing electrolyte (TE) ion. The first zone and the second zone are configured to be operably connected to at least one anode and at least one cathode.
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公开(公告)号:US20190189897A1
公开(公告)日:2019-06-20
申请号:US16323583
申请日:2017-08-10
Inventor: David ELATA
IPC: H01L41/09 , H01L41/047 , B81B3/00
CPC classification number: H01L41/096 , B81B3/0024 , H01L41/047 , H01L41/094 , H01L41/0993
Abstract: Single bulk unimorph piezoelectric elements, with interdigitated electrodes aligned obliquely relative to the direction perpendicular to the axis of the element, such that a torsional response is induced into the element. When such elements are used as a beam structure, with angularly oriented electrodes on both opposite surfaces of the beam, and with their orientations at mutually opposite angles, motion ranging from pure torsional rotation to pure bending can be obtained, depending on the comparative level and polarity of the voltages applied to each of the two electrode sets. If such elements are used as the spiral support arms of a central platform, a large displacement of the stage can be achieved. Due to the oblique orientation of the IDE's, the piezoelectric transduction induces torsional deformation in the spirals, and this torsion is converted by the spiral arms to a parallel out-of-plane platform motion.
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公开(公告)号:US20190152811A1
公开(公告)日:2019-05-23
申请号:US16316643
申请日:2017-07-10
Inventor: Hagai COHEN , Ilya LOIFERMAN , Matthew SUSS
IPC: C02F1/469 , H01M8/18 , H01M8/22 , C02F1/461 , H01M8/0202
Abstract: Provided is an electrode including conductive particles, which sediment under gravitational force and a liquid fluidizing medium flowing through the electrode, in which the conductive particles are suspended and optionally further including conductive particles, which do not sediment under gravitational force when the fluidizing medium flows in the electrode. Further provided are electrochemical devices and energy storage systems including the electrode.
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公开(公告)号:US10225533B2
公开(公告)日:2019-03-05
申请号:US14680461
申请日:2015-04-07
Inventor: Aaron Wetzler , Ron Kimmel
Abstract: A system comprising: a handheld mobile device comprising: a projector unit configured to project an image; a camera; and a prism configured to reflect the image projected by the projector such that the camera can capture the projected image.
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