公开(公告)号：US07507395B2

公开(公告)日：2009-03-24

申请号：US10958670

申请日：2004-10-04

申请人： Zhenjun Diwu ,  Jesse J. Twu ,  Guoliang Yi ,  Luke D. Lavis ,  Yen-Wen Chen ,  Kelly J. Cassutt

发明人： Zhenjun Diwu ,  Jesse J. Twu ,  Guoliang Yi ,  Luke D. Lavis ,  Yen-Wen Chen ,  Kelly J. Cassutt

IPC分类号： A61K49/00 ,  C12Q1/44 ,  C07D311/82 ,  C07D407/00

CPC分类号： C07D493/10 ,  C07D311/82 ,  G01N1/30 ,  G01N33/84 ,  G01N2001/302 ,  G01N2800/04

摘要： Systems, including compositions and methods, for measuring pH, particularly in cells, organelles, and other samples. The compositions include pH-sensitive fluorescent and fluorogenic 2′,7′-dialkylfluorescein derivatives and associated nonfluorescent precursor compounds. The compositions may permit ratiometric measurement in the excitation spectrum and the emission spectrum. The methods include adding a precursor compound to a sample cell, incubating the sample cell to release the free indicator, illuminating the sample cell, and detecting the fluorescence response of the free indicator.

摘要翻译： 用于测量pH的系统，包括组合物和方法，特别是在细胞，细胞器和其它样品中。 组合物包括pH敏感的荧光和荧光2'，7'-二烷基荧光素衍生物和相关的非荧光前体化合物。 组合物可以允许在激发光谱和发射光谱中进行比例测量。 所述方法包括向样品池中加入前体化合物，孵育样品池以释放游离指示物，照射样品池，以及检测游离指示剂的荧光响应。

公开(公告)号：US07464463B2

公开(公告)日：2008-12-16

申请号：US11219557

申请日：2005-09-02

申请人： Jao-Ching Lin ,  Pei-Pei Ding ,  Hsiu-Wei Yang ,  Wen-Hwa Yu ,  Yen-Wen Chen

发明人： Jao-Ching Lin ,  Pei-Pei Ding ,  Hsiu-Wei Yang ,  Wen-Hwa Yu ,  Yen-Wen Chen

IPC分类号： B23P6/00

CPC分类号： H01L23/427 ,  B23P15/26 ,  B23P2700/10 ,  F28D15/0233 ,  F28D15/0283 ,  F28D15/046 ,  H01L21/4882 ,  H01L2924/0002 ,  Y10T29/49353 ,  H01L2924/00

摘要： A method for making a heat dissipating device includes the steps of: mounting an elastically deformable member on a container body in such a manner that the elastically deformable member covers a periphery of an opening in the container body and that the elastically deformable member cooperates with the container body to define a cavity in fluid communication with an inner space in the container body through the opening; vacuuming the inner space in such a manner that air in the inner space is drawn through the opening and the cavity to the outside of the container body; filling the inner space with a predetermined amount of a working fluid through the opening and the cavity; and forming a sealing mechanism that functions to isolate the inner space from the opening.

摘要翻译： 一种制造散热装置的方法包括以下步骤：将可弹性变形的部件安装在容器本体上，使得可弹性变形的部件覆盖容器主体中的开口的周边，并且可弹性变形的部件与 容器体以限定通过开口与容器主体中的内部空间流体连通的空腔; 以使得内部空间中的空气通过开口和空腔被抽吸到容器主体的外部的方式抽吸内部空间; 通过所述开口和所述空腔用预定量的工作流体填充所述内部空间; 以及形成用于将内部空间与开口隔离的密封机构。

公开(公告)号：US20080067534A1

公开(公告)日：2008-03-20

申请号：US11878193

申请日：2007-07-23

申请人： Min-Hsun Hsieh ,  Ta-Cheng Hsu ,  ML Tsai ,  Chih-Chiang Lu ,  Chien-Yuan Wang ,  Yen-Wen Chen ,  Ya-Ju Lee

发明人： Min-Hsun Hsieh ,  Ta-Cheng Hsu ,  ML Tsai ,  Chih-Chiang Lu ,  Chien-Yuan Wang ,  Yen-Wen Chen ,  Ya-Ju Lee

IPC分类号： H01L33/00

CPC分类号： H01L33/50 ,  H01L33/486 ,  H01L33/507 ,  H01L33/54 ,  H01L33/60 ,  H01L33/62 ,  H01L33/64 ,  H01L33/641 ,  H01L2224/48091 ,  H01L2224/49107 ,  H01L2924/01322 ,  H01L2924/00014

摘要： This disclosure relates to a light-emitting apparatus comprising a submount, a chip carrier formed on the submount, a light-emitting chip formed on the chip carrier, a reflecting cup formed on the submount and enclosing the light-emitting chip and the chip carrier, and a transparent encapsulating material for encapsulating the light-emitting chip.

摘要翻译： 本公开涉及一种发光装置，其包括基座，形成在基座上的芯片载体，形成在芯片载体上的发光芯片，形成在基座上并包围发光芯片和芯片载体的反射杯 以及用于封装发光芯片的透明封装材料。

公开(公告)号：US20060289881A1

公开(公告)日：2006-12-28

申请号：US11308981

申请日：2006-06-02

申请人： Yen-Wen Chen ,  Wen-Huang Liu ,  Wei-Chih Peng

发明人： Yen-Wen Chen ,  Wen-Huang Liu ,  Wei-Chih Peng

IPC分类号： H01L33/00

CPC分类号： H01L33/38 ,  H01L33/20

摘要： A semiconductor light emitting device including a substrate, a semiconductor light emitting stack, a first electrode, a first transparent oxide conductive layer and a second electrode is provided. The semiconductor light emitting stack is disposed on the substrate and has a first surface region and a second surface region. The first electrode is disposed on the first surface region. The first transparent oxide conductive layer is disposed on the second surface region. The second electrode is disposed on the first transparent oxide conductive layer. The area of the light emitting device is larger than 2.5×105 μm2, and the distance between the first electrode and the second electrode is between 150 μm and 250 μm essentially, and the area of the first electrode and the second electrode is 15%˜25% of that of the light emitting layer.

摘要翻译： 提供了包括基板，半导体发光堆叠，第一电极，第一透明氧化物导电层和第二电极的半导体发光器件。 半导体发光堆叠设置在基板上并具有第一表面区域和第二表面区域。 第一电极设置在第一表面区域上。 第一透明氧化物导电层设置在第二表面区域上。 第二电极设置在第一透明氧化物导电层上。 发光器件的面积大于2.5×10 5 m 2，并且第一电极和第二电极之间的距离基本上在150μm和250μm之间， 并且第一电极和第二电极的面积为发光层的面积的15％〜25％。

公开(公告)号：US20050136503A1

公开(公告)日：2005-06-23

申请号：US10958670

申请日：2004-10-04

申请人： Zhenjun Diwu ,  Jesse Twu ,  Guoliang Yi ,  Luke Lavis ,  Yen-Wen Chen ,  Kelly Cassutt

发明人： Zhenjun Diwu ,  Jesse Twu ,  Guoliang Yi ,  Luke Lavis ,  Yen-Wen Chen ,  Kelly Cassutt

IPC分类号： C07D311/82 ,  C07D493/10 ,  G01N1/30 ,  G01N33/84 ,  C12Q1/34 ,  G01N33/48

CPC分类号： C07D493/10 ,  C07D311/82 ,  G01N1/30 ,  G01N33/84 ,  G01N2001/302 ,  G01N2800/04

摘要： Systems, including compositions and methods, for measuring pH, particularly in cells, organelles, and other samples. The compositions include pH-sensitive fluorescent and fluorogenic 2′,7′-dialkylfluorescein derivatives and associated nonfluorescent precursor compounds. The compositions may permit ratiometric measurement in the excitation spectrum and the emission spectrum. The methods include adding a precursor compound to a sample cell, incubating the sample cell to release the free indicator, illuminating the sample cell, and detecting the fluorescence response of the free indicator.

摘要翻译： 用于测量pH的系统，包括组合物和方法，特别是在细胞，细胞器和其它样品中。 组合物包括pH敏感的荧光和荧光2'，7'-二烷基荧光素衍生物和相关的非荧光前体化合物。 组合物可以允许在激发光谱和发射光谱中进行比例测量。 所述方法包括向样品池中加入前体化合物，孵育样品池以释放游离指示物，照射样品池，以及检测游离指示剂的荧光响应。

公开(公告)号：US06557416B2

公开(公告)日：2003-05-06

申请号：US09801777

申请日：2001-03-09

申请人： I-Nan Chang ,  Chung Chih Lo ,  Wu Chin Chen ,  Yen-Wen Chen

发明人： I-Nan Chang ,  Chung Chih Lo ,  Wu Chin Chen ,  Yen-Wen Chen

IPC分类号： G01N3348

CPC分类号： G01N29/036 ,  G01N29/348 ,  G01N29/36 ,  G01N2291/02466 ,  G01N2291/101

摘要： A high resolution biosensing system for detecting and identifying a biochemical material to be tested by using proportional relationship between frequency variation of oscillation and mass of the biochemical material to be tested comprises a biosensor; an oscillatorfor generating oscillation based on the sensed result; a phase-lock loop circuit receiving the oscillation of the oscillator and generating pulse signals;an ultra-high frequency counter for counting the pulse signals; and a microprocessor for storing and displaying output from the ultra-high frequency counter and for controlling the oscillator. The phase-lock loop circuit generates the pulse signals of a frequency, which is n times the frequency of the oscillator and with a constant phase difference therebetween to trigger the ultra-high frequency counter. Accordingly, the resolution can be raised up to n times.

摘要翻译： 用于通过使用振荡频率变化与所测试的生化材料的质量之间的比例关系来检测和识别待测试的生化材料的高分辨率生物传感系统包括生物传感器; 基于感测结果产生振荡的振荡器; 接收振荡器的振荡并产生脉冲信号的锁相环电路;用于对脉冲信号进行计数的超高频计数器; 以及用于存储和显示来自超高频计数器的输出并用于控制振荡器的微处理器。 锁相环电路产生频率的n倍的脉冲信号，其频率为振荡器频率的n倍，并且在其之间具有恒定的相位差以触发超高频​​计数器。 因此，分辨率可以提高到n倍。