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公开(公告)号：US20090148424A1
公开(公告)日：2009-06-11
申请号：US10594544
申请日：2004-03-31
CPC分类号： C12N5/067 , A01K2207/15 , A01K2227/106 , A01K2267/035 , A61K35/12 , A61M1/3689 , C12N2510/04 , C12N2800/30
摘要： The present invention provides a reversibly immortalized mammalian liver cell line, especially CYNK-1 (deposited with International Patent Organism Depository, National Institute of Advanced Industrial Science and Technology, address: AIST Tsukuba Central 6, 1-1, Higashi 1-Chome, Tsukuba-shi, Ibaraki-ken, 305-8566 Japan, deposited date: Mar. 10, 2004, accession number: FERM BP-08657) comprising an immortalizing gene interposed between a pair of site-specific recombination sequences and a suicide gene in the outside of the pair of site-specific recombination sequences, characterized in that the suicide gene can exhibit its function after excision of the pair of site-specific recombination sequences, or passage cell line thereof; a mammalian liver cell obtained by excising the immortalizing gene from the reversibly immortalized mammalian liver cell line or passage cell line thereof; and use of these cells. By utilizing the reversibly immortalized mammalian liver cell line of the present invention enables the obtainment of the number of the liver cells and utilization as materials for artificial liver reactors and cell preparations.
摘要翻译： 本发明提供了可逆地永生化的哺乳动物肝细胞系，特别是CYNK-1（保藏在国际专利生物保藏中心，国立先进工业科学和技术研究所，地址：筑波中心6-1-1，Higashi 1-Chome，Tsukuba -shi，Ibaraki-ken，305-8566日本，保藏日期：2004年3月10日，登录号：FERM BP-08657），其包含插入一对位点特异性重组序列之间的永生化基因和外部的自杀基因 的特异性重组序列，其特征在于，自杀基因可以在切除一对位点特异性重组序列或其通过细胞系后显示其功能; 通过从可逆永生化的哺乳动物肝细胞系或其通过细胞系切除永生化基因获得的哺乳动物肝细胞; 并使用这些细胞。 通过利用本发明的可逆永生化的哺乳动物肝细胞系，可以获得肝细胞的数量和用作人造肝反应器和细胞制剂的材料。
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52.发明授权公开(公告)号：US07209676B2
公开(公告)日：2007-04-24
申请号：US10865758
申请日：2004-06-14
CPC分类号： G03G21/1871 , G03G2221/166
摘要： An electrophotographic image forming apparatus to which a cartridge is detachably mountable for forming an image on a recording medium. The apparatus includes a main body electrical contact member having a main body electrical contact electrically connected to a cartridge electrical contact to supply electric power to an electric power supplied member of the cartridge when the cartridge is mounted on the apparatus main body. The main body electrical contact is movable relative to the apparatus main body. The apparatus also includes an electrical contact cover member having an exposed portion for exposing the main body electrical contact, and covering the main body electrical contact member, and attached to the main body electrical contact member so that the exposed portion is movable relative to the main body electrical contact member. The electrical contact cover member is moved so that the two contacts are electrically connected together in the exposed portion.
摘要翻译： 一种电子照相图像形成装置，其中盒可拆卸地安装用于在记录介质上形成图像。 该装置包括主体电接触构件，该主体电接触构件具有电气连接到盒电接触件的主体电接触件，以在盒安装在设备主体上时向电源供应构件提供电力。 主体电接触件可相对于设备主体移动。 该装置还包括具有用于暴露主体电气接触的暴露部分并且覆盖主体电接触构件并且附接到主体电接触构件的暴露部分的电接触盖构件，使得露出部分相对于主体电接触构件可移动 身体电气接触构件。 电接触盖构件被移动，使得两个触点在暴露部分中电连接在一起。
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公开(公告)号：US20060239967A1
公开(公告)日：2006-10-26
申请号：US10520901
申请日：2003-07-07
IPC分类号： A61K48/00 , C12N15/861 , C12N7/00
CPC分类号： A61K48/0058 , C12N9/1241
摘要： By using a virus having a gene sequence comprising a telomerase promoter and an E1 gene (preferably a sequence comprising E1A gene, IRES sequence and E1B gene) or by using an anticancer agent comprising the virus, the virus replicates in cancer cells to thereby produce an efficient anticancer effect.
摘要翻译： 通过使用具有包含端粒酶启动子和E1基因（优选为E1A基因，IRES序列和E1B基因的序列）的基因序列的病毒，或者通过使用包含该病毒的抗癌剂，将该病毒复制在癌细胞中， 有效的抗癌作用。
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54.发明申请公开(公告)号：US20060188285A1
公开(公告)日：2006-08-24
申请号：US11407153
申请日：2006-04-20
IPC分类号： G03G15/00
CPC分类号： G03G21/1871 , G03G2221/166
摘要： An electrophotographic image forming apparatus to which a cartridge is detachably mountable for forming an image on a recording medium, having a main body electrical contact member having a main body electrical contact electrically connected to a cartridge electrical contact of the cartridge in order to supply electric power to an electric power supplied member of the cartridge when the cartridge is mounted on the apparatus main body, the main body electrical contact being movable relative to the apparatus main body, and an electrical contact cover member having an exposed portion for exposing the main body electrical contact, and covering the main body electrical contact member, and attached to the main body electrical contact member so that the exposed portion is movable relative to the main body electrical contact member, wherein in operative association with the operation of mounting the cartridge on the apparatus main body, the electrical contact cover member is moved relative to the main body electrical contact member so that the cartridge electrical contact and the main body electrical contact are electrically connected together in the exposed portion.
摘要翻译： 一种电子照相图像形成装置，其中可拆卸地安装用于在记录介质上形成图像的盒，其具有主体电接触构件，该主体电接触构件具有电连接到盒的盒电触点的主体电触点，以便提供电力 当盒被安装在设备主体上时，主体电接触件可相对于设备主体移动，并且具有用于将主体电气暴露的暴露部分的电接触盖部件连接到盒的供电部件， 接触并覆盖主体电接触构件，并且附接到主体电接触构件，使得暴露部分可相对于主体电接触构件移动，其中与将盒安装在设备上的操作相关联 主体，电接触盖构件相对于其移动 主体电接触构件，使得盒电触头和主体电触头在暴露部分中电连接在一起。
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公开(公告)号：US07079268B1
公开(公告)日：2006-07-18
申请号：US09503478
申请日：2000-02-14
申请人： Noriaki Tanaka
发明人： Noriaki Tanaka
CPC分类号： G06F3/1208 , G06F3/126 , G06F3/1288 , H04L67/10 , H04L67/1097 , H04L69/329
摘要： Disclosed are a printing system and a method of controlling the same, in which a terminal device storing image information to be printed is specified by an order management unit (203) in accordance with print requests from a plurality of terminal devices. Depending upon whether the specified terminal device and a printer to perform printing are connected locally or via a network (204), the specified terminal device is instructed to transfer the image information to a printer to perform printing. As a result, printing can be performed efficiently by a plurality of printers in response to print requests from a plurality of terminal devices connected via a network.
摘要翻译： 公开了一种打印系统及其控制方法，其中存储要打印的图像信息的终端设备根据来自多个终端设备的打印请求由订单管理单元（203）指定。 根据指定的终端设备和执行打印的打印机是否在本地或经由网络（204）连接，指示指定的终端设备将图像信息传送到打印机以进行打印。 结果，响应于来自经由网络连接的多个终端装置的打印请求，可以通过多个打印机有效地执行打印。
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公开(公告)号：US07027763B2
公开(公告)日：2006-04-11
申请号：US10724634
申请日：2003-12-02
IPC分类号： G03G15/20
CPC分类号： G03G15/2025
摘要： The image heating apparatus for heating an image formed on a recording material includes a heater, a supporting member for supporting the heater, a flexible rotatable member rotated while contacting with the heater, and a backup member contacting with the rotatable member. The recording material passes between the rotatable member and the backup member, and upstream of the heater of the supporting member with respect to the direction of movement of the recording material, there are provided a protruding portion protruding more toward the backup member side than the surface of contact between the heater and the rotatable member, and a groove portion provided between the protruding portion and the heater and depressed more than the surface of contact of the heater with the rotatable member, and a lubricant is contained in the groove portion. Thereby, the driving torque of the rotatable member can be suppressed.
摘要翻译： 用于加热形成在记录材料上的图像的图像加热装置包括加热器，用于支撑加热器的支撑构件，与加热器接触的同时旋转的柔性可旋转构件以及与可旋转构件接触的支撑构件。 记录材料相对于记录材料的移动方向通过可旋转构件和支撑构件之间以及支撑构件的加热器的上游侧，设置有突出部分比表面更靠近支撑构件侧突出 所述加热器和所述可旋转构件之间的接触，以及设置在所述突出部分和所述加热器之间并且比所述加热器与所述可旋转构件的接触表面更多地凹陷的凹槽部分，并且所述凹槽部分中包含润滑剂。 由此，能够抑制旋转部件的驱动扭矩。
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公开(公告)号：US4799051A
公开(公告)日：1989-01-17
申请号：US58906
申请日：1987-06-05
申请人： Noriaki Tanaka
发明人： Noriaki Tanaka
CPC分类号： G09G5/10
摘要： In a display control apparatus wherein a picture signal of a character, a pattern or the like and a luminance signal for affording a luminance to the picture signal are synchronously derived, and a logic between the picture signal and the luminance signal is taken to control the luminance of the picture signal; a display control apparatus comprising pulse width adjusters by which, when one signal is true with the other signal being false, the true signal is put within an interval of the false signal and is held false for fixed times before and after a true signal interval thereof, and when both logics of the respective signals are true or false, true or false intervals of both the signals are adjusted so as to become equal.
摘要翻译： 在同步导出字符，图案等的图像信号和用于提供图像信号的亮度的亮度信号的显示控制装置中，并且采用图像信号和亮度信号之间的逻辑来控制 图像信号的亮度; 一种显示控制装置，包括脉冲宽度调节器，当一个信号为真，另一个信号为假时，真实信号置于假信号的间隔内，并在其真实信号间隔之前和之后的固定时间内保持为假 ，并且当各个信号的逻辑都为真或假时，两个信号的真或间隔被调整以变得相等。
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