Biodegradable polymer
    56.
    发明授权
    Biodegradable polymer 有权
    生物降解聚合物

    公开(公告)号:US07722894B2

    公开(公告)日:2010-05-25

    申请号:US10277562

    申请日:2002-10-21

    IPC分类号: A61F13/00

    CPC分类号: C08G63/12

    摘要: A biodegradable polymer comprising a condensation polymer of glycerol and a diacid. The polymer may be adapted for use as a tissue engineering construct. For example, it may be seeded with cells or molecules may be attached to it to modify the metabolism and proliferation of cells or to modify the degradation rate and/or mechanism of the polymer. The polymer may also be exploited in a variety of medical and non-medical applications.

    摘要翻译: 包含甘油和二酸的缩聚物的可生物降解的聚合物。 聚合物可适用于组织工程构造。 例如,可以用细胞接种细胞或分子可以连接到细胞上以修饰细胞的代谢和增殖或改变聚合物的降解速率和/或机制。 聚合物也可以用于各种医疗和非医疗应用。

    Nicotine Immunonanotherapeutics
    59.
    发明申请
    Nicotine Immunonanotherapeutics 有权
    尼古丁免疫治疗

    公开(公告)号:US20100092425A1

    公开(公告)日:2010-04-15

    申请号:US12428388

    申请日:2009-04-22

    CPC分类号: A61K39/00

    摘要: The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.

    摘要翻译: 本发明提供用于将纳米载体递送至免疫系统细胞的组合物和系统。 本发明提供能够刺激T细胞和/或B细胞中的免疫应答的纳米载体。 本发明提供包含具有多个尼古丁部分的免疫表面的纳米载体。 本发明提供包含本发明纳米载体的药物组合物。 本发明提供了设计,制造和使用本发明的纳米载体及其药物组合物的方法。 例如,本发明能够引发免疫应答的纳米载体和抗尼古丁抗体的产生。